NMC case report journal最新文献

Spontaneous Regression of Rathke's Cleft Cysts: A Report of Three Cases.

NMC case report journal Pub Date : 2025-03-07 eCollection Date: 2025-01-01 DOI: 10.2176/jns-nmc.2024-0238

Yumi Kondo, Yasuo Sasagawa, Sho Tamai, Mitsutoshi Nakada

{"title":"Spontaneous Regression of Rathke's Cleft Cysts: A Report of Three Cases.","authors":"Yumi Kondo, Yasuo Sasagawa, Sho Tamai, Mitsutoshi Nakada","doi":"10.2176/jns-nmc.2024-0238","DOIUrl":"10.2176/jns-nmc.2024-0238","url":null,"abstract":"Herein, we present 3 cases of Rathke's cleft cysts that shrank spontaneously within a short period. In addition, we present a literature review, discussing the characteristics and of action mechanisms of rapid Rathke's cleft cyst regression. Case 1 was that in a 17-year-old boy diagnosed with an Rathke's cleft cyst on the basis of magnetic resonance imaging. The Rathke's cleft cysts had expanded to compress the optical chiasm. Therefore, surgical intervention was planned. However, without any medical treatment, magnetic resonance imaging performed 3 months later revealed a spontaneous reduction in size, and surgery was canceled. Case 2 was in a 10-year-old boy who presented with a severe headache. Surgery was planned for a sellar cystic lesion; however, magnetic resonance imaging performed 2 months later revealed spontaneous shrinkage without any treatment. The patient's symptoms disappeared, and the surgery was canceled. Case 3 was in a 25-year-old man who presented with a headache. Magnetic resonance imaging at presentation revealed a cystic lesion in the sella turcica, but repeat magnetic resonance imaging 4 months later revealed spontaneous shrinkage. Fifty-nine cases of spontaneously shrinking Rathke's cleft cysts, initially characterized by severe headache (54.2%), have been reported; of these, 57% of cases were in patients younger than 39 years. Furthermore, 64% of patients showed evidence of cyst reduction on magnetic resonance imaging within 6 months. Type 1-weighted magnetic resonance imaging scans showed isointensity or high signal intensity in 91% of cases. In conclusion, spontaneous shrinkage of Rathke's cleft cysts can occur within a few months. Type 1-weighted images are characterized by high signal intensity, and episodic headaches may indicate shrinkage. The possibility of short-term regression of Rathke's cleft cyst should be considered before scheduled surgery.","PeriodicalId":101331,"journal":{"name":"NMC case report journal","volume":"12 ","pages":"79-84"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11947417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Case of Giant Congenital/Infant-type Hemispheric Glioma Harboring Concomitant ALK and EGFR Alteration.

NMC case report journal Pub Date : 2025-03-07 eCollection Date: 2025-01-01 DOI: 10.2176/jns-nmc.2023-0286

Derya Karatas, Saygi Uygur, Irmak Tekeli Barut, Hamide Sayar, Ahmet Dagtekin, Emel Avci

{"title":"A Rare Case of Giant Congenital/Infant-type Hemispheric Glioma Harboring Concomitant ALK and EGFR Alteration.","authors":"Derya Karatas, Saygi Uygur, Irmak Tekeli Barut, Hamide Sayar, Ahmet Dagtekin, Emel Avci","doi":"10.2176/jns-nmc.2023-0286","DOIUrl":"10.2176/jns-nmc.2023-0286","url":null,"abstract":"Infant-type hemispheric glioma is a subtype of pediatric high-grade glioma that is seen among those under the age of 3-5 years and congenital infant-type hemispheric gliomas are another subtype which is seen among those under 6 months of age. The molecular features and overall survival of infant-type hemispheric gliomas are distinct from those of pediatric and adult high-grade gliomas. The present study reports a fraternal twin case of a giant hemispheric infant-type hemispheric glioma diagnosed at the age of 2 months and treated with gross total resection. Even though the Ki-67 proliferative index of the tumor was 70%, she has been surviving for 4 years. After molecular analysis, the first case of infant-type hemispheric glioma that had concurrent echinoderm microtubule-associated protein-like 4::anaplastic lymphoma kinase gene fusion and an A269V point mutation on exon 7 in epidermal growth factor receptor gene was identified. Among echinoderm microtubule-associated protein-like 4::anaplastic lymphoma kinase gene fusion cases, the present study presents a rare twin case of giant infant-type hemispheric glioma that has a long recurrence-free survival without radiation or targeted therapy. In contrast, the neurocognitive test results of this case at the age of 4 years corresponded to 12-15 months of age.","PeriodicalId":101331,"journal":{"name":"NMC case report journal","volume":"12 ","pages":"73-78"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11947719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined Transcranial and Endonasal Approach for Clipping of a Partially Thrombosed Giant Aneurysm of the Lower Basilar Artery.

NMC case report journal Pub Date : 2025-03-07 eCollection Date: 2025-01-01 DOI: 10.2176/jns-nmc.2024-0240

Ryohei Saito, Takeshi Mikami, Yukinori Akiyama, Katsuya Komatsu, Yasuhiro Takahashi, Ayumu Yamaoka, Sho Matsunaga, Nobuhiro Mikuni

{"title":"Combined Transcranial and Endonasal Approach for Clipping of a Partially Thrombosed Giant Aneurysm of the Lower Basilar Artery.","authors":"Ryohei Saito, Takeshi Mikami, Yukinori Akiyama, Katsuya Komatsu, Yasuhiro Takahashi, Ayumu Yamaoka, Sho Matsunaga, Nobuhiro Mikuni","doi":"10.2176/jns-nmc.2024-0240","DOIUrl":"10.2176/jns-nmc.2024-0240","url":null,"abstract":"The conventional transcranial approach for treating lower basilar artery aneurysms is challenging because the deep and narrow surgical field limits surgical maneuvering for clipping. We report a case of a 77-year-old female who presented with right hemiparesis caused by a partially thrombosed giant aneurysm in her lower basilar artery. We performed neck clipping and thrombus debulking using a combined transcranial and endonasal approach. This approach enabled us to secure the parent artery from the endonasal side, which is difficult to achieve with the transcranial approach alone. It also allowed for early thrombus removal, thereby widening the surgical field on the transcranial side. Additionally it compensated for the transcranial blind spot by observing the clip tip from the endonasal side. After surgery, the patient required 3 months of rehabilitation for residual right hemiparesis before being discharged. Follow-up imaging revealed a reduction in the size of the partially thrombosed aneurysm. To our knowledge, this is the first report of a combined transcranial and endonasal approach for the treatment of a basilar artery aneurysm. For lower basilar artery aneurysms, this combined approach may offer advantages in achieving safe parent artery control, thrombus debulking, and neck clipping.","PeriodicalId":101331,"journal":{"name":"NMC case report journal","volume":"12 ","pages":"59-64"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11947416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Verbal Memory Localized in Non-language-dominant Hemisphere: Atypical Lateralization Revealed by Material-specific Memory Evaluation Using Super-selective Wada Test.

NMC case report journal Pub Date : 2025-03-07 eCollection Date: 2025-01-01 DOI: 10.2176/jns-nmc.2024-0217

Hana Kikuchi, Shin-Ichiro Osawa, Kazuo Kakinuma, Shoko Ota, Kazuto Katsuse, Kazushi Ukishiro, Kazutaka Jin, Hidenori Endo, Nobukazu Nakasato, Kyoko Suzuki

{"title":"Verbal Memory Localized in Non-language-dominant Hemisphere: Atypical Lateralization Revealed by Material-specific Memory Evaluation Using Super-selective Wada Test.","authors":"Hana Kikuchi, Shin-Ichiro Osawa, Kazuo Kakinuma, Shoko Ota, Kazuto Katsuse, Kazushi Ukishiro, Kazutaka Jin, Hidenori Endo, Nobukazu Nakasato, Kyoko Suzuki","doi":"10.2176/jns-nmc.2024-0217","DOIUrl":"10.2176/jns-nmc.2024-0217","url":null,"abstract":"Hippocampectomy is effective for drug-resistant mesial temporal lobe epilepsy with hippocampal sclerosis. However, multiple studies have reported high risks associated with hippocampectomy in patients with mesial temporal lobe epilepsy without hippocampal sclerosis on magnetic resonance imaging and in those with preserved memory function. Verbal memory and language functions are believed to coexist in the same hemisphere. We present a case of left mesial temporal lobe epilepsy with atypical memory function lateralization revealed by super-selective infusion of propofol to the intracranial artery (super-selective Wada test). A 24-year-old right-handed man with drug-resistant focal impaired awareness seizures was diagnosed with left mesial temporal lobe epilepsy without hippocampal sclerosis, but he showed preserved verbal intelligence quotient and memory, suggesting a high risk of severe memory decline after hippocampectomy. We performed super-selective Wada test to the posterior cerebral artery to assess the lateralization of verbal and visual memory separately, and to the middle cerebral artery to assess language function. The results revealed right-sided dominance for both verbal and visual memory, although the language was left-dominant. Hippocampectomy was performed and resulted in freedom from seizures. Memory assessments 1 year postoperatively showed no decline in all subtests. In patients with drug-resistant epilepsy exhibiting atypical neuropsychological profiles, the memory-dominant, and language-dominant hemispheres may not align; detailed evaluations of function lateralization are necessary for tailored treatment.","PeriodicalId":101331,"journal":{"name":"NMC case report journal","volume":"12 ","pages":"65-71"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11947419/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Symptomatic Improvement after Surgical Transposition of an Extremely Medialized Carotid Artery Causing Swallowing Discomfort: A Case Report.

NMC case report journal Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.2176/jns-nmc.2024-0158

Nobuto Hirai, Ryuichiro Kajikawa, Yusuke Nishikawa, Motoki Nakamura, Eisaku Terada, Shuhei Kawabata, Takashi Tsuzuki

{"title":"Symptomatic Improvement after Surgical Transposition of an Extremely Medialized Carotid Artery Causing Swallowing Discomfort: A Case Report.","authors":"Nobuto Hirai, Ryuichiro Kajikawa, Yusuke Nishikawa, Motoki Nakamura, Eisaku Terada, Shuhei Kawabata, Takashi Tsuzuki","doi":"10.2176/jns-nmc.2024-0158","DOIUrl":"10.2176/jns-nmc.2024-0158","url":null,"abstract":"An aberrant course of the carotid artery can cause dysphagia by displacing the pharynx, but no definitive treatment strategy has been established for this condition. We report a case in which swallowing discomfort was improved by surgical transposition of a carotid artery following a highly medial course. A 79-year-old man presented with worsening swallowing discomfort over the preceding year. Computed tomography angiography of the head and neck showed tortuous right common and internal carotid arteries running through the retropharyngeal space. Videoendoscopic and videofluorographic examinations revealed intact swallowing function and the carotid artery compressing the right pharyngeal wall. Since the cause of swallowing discomfort was suspected to be the tortuous courses of the right common and internal carotid arteries, we performed surgery to change the course of the carotid artery. The surgical procedure moved the common and internal carotid arteries from the retropharyngeal space. The carotid artery was retracted anterolaterally with the carotid sheath, which was fixed to the sternocleidomastoid muscle to maintain the corrected course. Symptoms showed immediate improvement postoperatively. Our strategy appears effective as a method of treating swallowing discomfort due to tortuosity of the carotid arteries.","PeriodicalId":101331,"journal":{"name":"NMC case report journal","volume":"12 ","pages":"27-31"},"PeriodicalIF":0.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful Endoscopic Resection of a Chronic Expanding Hematoma Following Gamma Knife Surgery for Cerebral Arteriovenous Malformation: A Case Report.

NMC case report journal Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.2176/jns-nmc.2024-0216

Shogo Wakita, Kentaro Horiguchi, Shigeki Nakano, Yoshinori Higuchi

{"title":"Successful Endoscopic Resection of a Chronic Expanding Hematoma Following Gamma Knife Surgery for Cerebral Arteriovenous Malformation: A Case Report.","authors":"Shogo Wakita, Kentaro Horiguchi, Shigeki Nakano, Yoshinori Higuchi","doi":"10.2176/jns-nmc.2024-0216","DOIUrl":"10.2176/jns-nmc.2024-0216","url":null,"abstract":"Gamma knife surgery is useful for treating cerebral arteriovenous malformations. However, some radiation-induced long-term complications have been reported. One of these is a chronic expanding hematoma. We present a case of chronic expanding hematoma, successfully treated with endoscopic resection. The patient, a woman in her 30s, experienced a cerebral hemorrhage 17 years ago associated with an arteriovenous malformation in the corpus callosum. The lesion was completely embolized with n-butyl-2-cyanoacrylate embolization twice, followed 2 years later by gamma knife surgery. The patient presented to the emergency room with headache and left hemiplegia. A computed tomography scan showed hemorrhagic changes consistent with the cystic lesion and worsening edematous changes around it. An endoscopic tumor resection (interhemispheric approach) was performed, and most of the lesion was removed. Pathology did not detect any neoplastic lesions, and a diagnosis of chronic expanding hematoma was performed based on the presence of abnormal vascular neoplasia. The postoperative course was uneventful, and the headache promptly resolved. The pathophysiology of chronic expanding hematoma involves slow and progressive hematoma expansion due to repeated local hemorrhage, causing intense cerebral edema around the lesion. Surgical removal is effective, and edematous changes and neurological symptoms can be quickly relieved after surgery. Endoscopic surgery is particularly effective for deep lesions owing to its ability to manipulate within a narrow surgical field. In this case, the lesion was removed with minimal invasiveness and no complications, leading to early symptom relief and resolution of the surrounding brain edema changes.","PeriodicalId":101331,"journal":{"name":"NMC case report journal","volume":"12 ","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Primary Spinal Intramedullary Mixed Germ Cell Tumor: A Case Report and Literature Review. 原发性脊髓髓内混合生殖细胞瘤：病例报告与文献综述

NMC case report journal Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.2176/jns-nmc.2024-0202

Shunsuke Nakamura, Hiroya Shimauchi-Ohtaki, Fumiaki Honda, Yuta Goto, Satoshi Nakata, Keishi Horiguchi, Ran Tomomasa, Junko Hirato, Hideaki Yokoo, Soichi Oya

{"title":"A Primary Spinal Intramedullary Mixed Germ Cell Tumor: A Case Report and Literature Review.","authors":"Shunsuke Nakamura, Hiroya Shimauchi-Ohtaki, Fumiaki Honda, Yuta Goto, Satoshi Nakata, Keishi Horiguchi, Ran Tomomasa, Junko Hirato, Hideaki Yokoo, Soichi Oya","doi":"10.2176/jns-nmc.2024-0202","DOIUrl":"10.2176/jns-nmc.2024-0202","url":null,"abstract":"Central nervous system germ cell tumors are rare and account for 2% to 3% of all central nervous system tumors in Japan. Here, we report an extremely rare case of a primary spinal intramedullary mixed germ cell tumor. A 33-year-old man presented with a chief report of dysuria and numbness in the right lower extremity. Magnetic resonance imaging revealed a mass lesion on the left side of the intramedullary spinal cord at the Th10-11 vertebral body level with hyperintensity on T2-weighted images, isointensity on T1-weighted images, and uniform contrast in gadolinium. Cerebrospinal fluid examination revealed a few atypical cells. Although tumor removal using the posterior median sulcus approach was attempted, only a biopsy was performed because intraoperative rapid pathology suggested a possible diagnosis of germinoma. Permanent pathology revealed a mixed germ cell tumor (mainly comprising a germinoma with a yolk sac tumor). Postoperatively, cerebrospinal irradiation and 8 courses of the carboplatin and etoposide regimen were administered. No recurrence or new lesions were observed on magnetic resonance imaging at 94 months postoperatively. Our extensive literature search found only 4 cases of a mixed germ cell tumor of primary intramedullary origin in the spinal cord. Most spinal germ cell tumors described in the literature are either germinomas or mature teratomas; however, mixed germ cell tumors can also occur, albeit infrequently. Although additional cases need to be accumulated, our case suggests that yolk sac elements in spinal mixed germ cell tumors might not be directly associated with poor life expectancy.","PeriodicalId":101331,"journal":{"name":"NMC case report journal","volume":"12 ","pages":"53-58"},"PeriodicalIF":0.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Intracranial Mesenchymal Tumor, FET::CREB Fusion-positive, Diagnosed by Genomic Profiling with FoundationOne CDx.

NMC case report journal Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.2176/jns-nmc.2024-0103

Kousuke Sono, Toshiyuki Enomoto, Hiromasa Kobayashi, Koichiro Takemoto, Takashi Morishita, Mikiko Aoki, Makoto Hamasaki, Hiroshi Abe

{"title":"A Case of Intracranial Mesenchymal Tumor, FET::CREB Fusion-positive, Diagnosed by Genomic Profiling with FoundationOne CDx.","authors":"Kousuke Sono, Toshiyuki Enomoto, Hiromasa Kobayashi, Koichiro Takemoto, Takashi Morishita, Mikiko Aoki, Makoto Hamasaki, Hiroshi Abe","doi":"10.2176/jns-nmc.2024-0103","DOIUrl":"10.2176/jns-nmc.2024-0103","url":null,"abstract":"Intracranial mesenchymal tumor FET::cyclic adenosine monophosphate response element-binding fusion-positive is a soft tissue tumor with an extremely rare intracranial occurrence. Histological diagnosis is sometimes difficult, requiring confirmation of characteristic fusion genes. The patient was a 45-year-old male who presented with a chief complaint of pain and an abnormal sensation in the right trigeminal nerve area, in whom a neoplastic lesion in Meckel's cave was noted. The preoperative diagnoses included meningioma and schwannoma. The tumor was extirpated as much as possible, and the tumor tissue showed a high proliferative potential with rhabdoid features, raising the suspicion of a rhabdoid meningioma. However, immunostaining was positive for desmin and cluster of differentiation 99, suggesting the possibility of angiomatoid fibrous histiocytoma. For diagnosis, Ewing sarcoma breakpoint region1 gene-cyclic adenosine monophosphate response element-binding 1 fusion and Ewing sarcoma breakpoint region1 gene-activating transcription factor 1 fusion were examined at our institution, but were undetectable and did not lead to a diagnosis. Genomic profiling with FoundationOne CDx (Foundation Medicine, Cambridge, MA, USA) confirmed Ewing sarcoma breakpoint region1 gene-cyclic adenosine monophosphate response element modulator fusion and a diagnosis of intracranial mesenchymal tumor FET::cyclic adenosine monophosphate response element-binding fusion-positive was made. Diagnosis of intracranial mesenchymal tumor FET::cyclic adenosine monophosphate response element-binding fusion-positive requires both histological examination and confirmation of the fusion gene. Genomic profiling using the FoundationOne CDx is also useful when the fusion gene cannot be sufficiently confirmed at an individual's institution.","PeriodicalId":101331,"journal":{"name":"NMC case report journal","volume":"12 ","pages":"33-39"},"PeriodicalIF":0.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gauze Packing and Removal: Two-staged Operations for Hemostasis of Traumatic Sinus Injury.

NMC case report journal Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.2176/jns-nmc.2024-0100

Hidekazu Nakata, Nao Shimooka, Takahiro Uno, Hanako Sasaki, Shiromaru Ishida, Makoto Dehara, Yasushi Hagihara

引用次数: 0

Pathogenesis of Spinal Subdural Hematoma Based on Histopathological Findings: A Case Report.

NMC case report journal Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.2176/jns-nmc.2024-0214

Yoshiki Fujikawa, Takahiro Fujishiro, Hideki Tanabe, Toshihiro Takami, Masahiko Wanibuchi

{"title":"Pathogenesis of Spinal Subdural Hematoma Based on Histopathological Findings: A Case Report.","authors":"Yoshiki Fujikawa, Takahiro Fujishiro, Hideki Tanabe, Toshihiro Takami, Masahiko Wanibuchi","doi":"10.2176/jns-nmc.2024-0214","DOIUrl":"10.2176/jns-nmc.2024-0214","url":null,"abstract":"Spinal subdural hematoma is a rare condition whereas intracranial chronic subdural hematoma is well-recognized and documented in clinical settings. Despite various theories that have been proposed, the exact pathogenesis of spinal subdural hematoma remains to be elucidated. Herein, we report a rare case of spinal subdural hematoma with a co-existing intracranial chronic subdural hematoma and deduce its etiology using histopathological findings. A 76-year-old Japanese man with slight hemiparesis due to intracranial chronic subdural hematoma underwent burr hole surgery with successful drainage of the hematoma. The patient could not walk unassisted after the surgery. Spinal magnetic resonance imaging was performed, revealing a subdural hematoma extending from the T11 to S2 levels. The patient subsequently underwent the evacuation of spinal subdural hematoma 12 days after initial surgery. Intraoperatively, we identified a dark liquefied hematoma with capsule formation. Histological examination of the resected capsule revealed loose fibrovascular tissues comprising capillaries, collagen fibers, a small number of macrophages, and hemosiderin deposits. These findings were very similar to the pathology of intracranial chronic subdural hematoma so the pathogenesis of spinal subdural hematoma in this case was considered identical to that of subacute or chronic subdural hematoma. The patient was transferred to a rehabilitation hospital, and 4 months after the lumbar surgery, no recurrence was observed in the magnetic resonance imaging examination. Subacute or chronic spinal subdural hematoma may result from various pathogeneses that clinicians should consider for correct diagnosis and appropriate management. Our case provides important insights into the pathogenesis of subacute or chronic spinal subdural hematoma.","PeriodicalId":101331,"journal":{"name":"NMC case report journal","volume":"12 ","pages":"41-46"},"PeriodicalIF":0.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0