Zeszyty Naukowe WCO, Letters in Oncology Science最新文献_第3页

Czy następuje zmiana struktury technik radioterapii na korzyść technik bardziej zaawansowanych?

Zeszyty Naukowe WCO, Letters in Oncology Science Pub Date : 2014-07-01 DOI: 10.1016/j.onko.2014.09.004

Katarzyna Paczkowska

引用次数: 0

Analiza wyników weryfikacji geometrycznej obrazów megawoltowych u pacjentek napromienianych w obszarze lewego gruczołu piersiowego

Zeszyty Naukowe WCO, Letters in Oncology Science Pub Date : 2014-07-01 DOI: 10.1016/j.onko.2014.09.003

Daria Wróbel , Agnieszka Skrobała , Tomasz Piotrowski

{"title":"Analiza wyników weryfikacji geometrycznej obrazów megawoltowych u pacjentek napromienianych w obszarze lewego gruczołu piersiowego","authors":"Daria Wróbel , Agnieszka Skrobała , Tomasz Piotrowski","doi":"10.1016/j.onko.2014.09.003","DOIUrl":"10.1016/j.onko.2014.09.003","url":null,"abstract":"<div><h3>Aim</h3><p>The aim of this study was to analyze the influence of the size of the clinical target volume (CTV) on the displacement obtained from the patients irradiated because of the left breast cancer using the geometric verification with the megavoltage images.</p></div><div><h3>Material and method</h3><p>Examined group of 100 patients was treated with the three-dimensional conformal radiotherapy. The analysis was performed on the 396 megavoltage images. The examined group of patients was divided into two subgroups according to the breast's CTV volume. The first subgroup (I) was the patient with the CTV≤700 cm<sup>3</sup> and the second (II) one CTV>700 cm<sup>3</sup>. The displacements were obtained in the three directions: anterior-posterior (AP), crania-caudal (CC) and left-right (LR). The systematic (Σ), random (σ) errors and safety margins (SM) were calculated.</p></div><div><h3>Results</h3><p>The range of the Σ error was 0,20–0,34cm for the (I) and 0,26–0,42cm for the (II). The maximum value of the σ error was 0,46–0,26cm, respectively. The lowest value of the SM was in the AP and the largest one in the CC direction. The SM ranges were 0,65–1,00cm for CTV≤700 cm<sup>3</sup> and 0,88–1,37cm for CTV>700 cm<sup>3</sup>. SM for the whole group of the breast patient was in the range 0,80–1,24cm.</p></div><div><h3>Conclusions</h3><p>The set-up of the breast patient with the smaller volume of the CTV≤700 cm<sup>3</sup> is much accurate and connected with smaller values of the geometric displacements. Safety margin used during the treatment planning should be selected individually depending on the size of the breast volume – CTV.</p></div>","PeriodicalId":101295,"journal":{"name":"Zeszyty Naukowe WCO, Letters in Oncology Science","volume":"11 3","pages":"Pages 53-60"},"PeriodicalIF":0.0,"publicationDate":"2014-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.onko.2014.09.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84824979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stereotaktyczna radioterapia niedrobnokomórkowego raka płuca we wczesnym stadium zaawansowania – czy napromienianie może zastąpić chirurgię?

Zeszyty Naukowe WCO, Letters in Oncology Science Pub Date : 2014-04-01 DOI: 10.1016/j.onko.2014.06.003

Piotr Janiga

引用次数: 2

Rola hormonoterapii w skojarzeniu z leczeniem miejscowym u chorych z rakiem prostaty o wysokim ryzyku progresji

Zeszyty Naukowe WCO, Letters in Oncology Science Pub Date : 2014-04-01 DOI: 10.1016/j.onko.2014.06.001

Tomasz Milecki, Andrzej Antczak, Zbigniew Kwias, Michał Hrab

{"title":"Rola hormonoterapii w skojarzeniu z leczeniem miejscowym u chorych z rakiem prostaty o wysokim ryzyku progresji","authors":"Tomasz Milecki, Andrzej Antczak, Zbigniew Kwias, Michał Hrab","doi":"10.1016/j.onko.2014.06.001","DOIUrl":"10.1016/j.onko.2014.06.001","url":null,"abstract":"<div><p>In the last decades, prostate cancer (PC) has become one of the most common cancer in Europe and in the United States. Hormonal therapy (HT) is the current mainstay for systemic treatment of patients with metastatic disease but lower disease patients are treated with local methods such as: radiation therapy (RT) or radical prostatectomy. However the efficacy of treatment for high-risk of disease progresion patients supported by RT and radical prostatectomy is not satisfactory. Experimental studies based on animal models showed that the idea of addition of HT to RT might improve the results of combined treatment. Outcomes from randomised trials indicated that combined treatment (HT plus RT) leads to significantly better overall and disease–specific survival results than RT alone. Nowadays the combination of long-term HT with RT is considered the treatment of choice for high-risk patients. For patients treated with radical prostatectomy the role of adjuvant HT is still controversial because there are a low number of trials which confirm the efficacy of this treatment modality.</p><p>In this review we summarize the available evidence from randomized III phase trials concerning the use of HT in both the RT and radical prostatectomy scenarios and also the most common side effects of HT.</p></div>","PeriodicalId":101295,"journal":{"name":"Zeszyty Naukowe WCO, Letters in Oncology Science","volume":"11 2","pages":"Pages 21-26"},"PeriodicalIF":0.0,"publicationDate":"2014-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.onko.2014.06.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91549063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Jakość życia pacjentów po leczeniu onkologicznym

Zeszyty Naukowe WCO, Letters in Oncology Science Pub Date : 2014-04-01 DOI: 10.1016/j.onko.2014.06.002

Grzegorz Pałucki

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Potencjalna przydatność wykrywania krążących komórek raka stercza w pilotażowej grupie chorych z zaawansowanym rakiem stercza

Zeszyty Naukowe WCO, Letters in Oncology Science Pub Date : 2014-01-01 DOI: 10.1016/j.onko.2014.03.003

Karolina Zaleska

引用次数: 1

Znaczenie terapii hormonalnej u pacjentów z przerzutowym opornym na kastrację rakiem stercza

Zeszyty Naukowe WCO, Letters in Oncology Science Pub Date : 2014-01-01 DOI: 10.1016/j.onko.2014.03.001

Tomasz Milecki, Andrzej Antczak

{"title":"Znaczenie terapii hormonalnej u pacjentów z przerzutowym opornym na kastrację rakiem stercza","authors":"Tomasz Milecki, Andrzej Antczak","doi":"10.1016/j.onko.2014.03.001","DOIUrl":"10.1016/j.onko.2014.03.001","url":null,"abstract":"<div><p>Metastatic prostate cancer, which shows progression despite castration testosterone levels, was previously defined as hormone-refractory. This definition has been recently changed to the one presently used-castrate-resistant prostate cancer. Numerous fundamental studies have provided the evidence that the development of hormone-refractory prostate cancer is constantly dependent on the concentration of androgens. The aim of the metastatic castrate-resistant prostate cancer treatment is currently to obtain the lowest possible androgen concentration. The effectiveness of such management has been proven by the results of clinical studies on the latest hormonal and chemotherapeutic medications. In the last two decades, new effective chemotherapeutics have become available on the market: abiraterone, enzalutamide, docetaxel, cabazitaxel, zoledronic acid, denosumab and alpharadin. They significantly contribute to extending patients’ survival and to improving their quality of life. Therefore, the question arises whether using LHRH analogues is still a necessary element of the therapy. A detailed analysis of study regimens involving the above-mentioned medications and of available publications support the view that LHRH analogues are the basic strategies in the treatment of patients with metastatic castrate-resistant prostate cancer. All clinical trials evaluating new therapies still followed the principle of obtaining castration testosterone levels as a result of using LHRH analogues simultaneously with the new medications.</p></div>","PeriodicalId":101295,"journal":{"name":"Zeszyty Naukowe WCO, Letters in Oncology Science","volume":"11 1","pages":"Pages 1-6"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.onko.2014.03.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73890645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rola adjuwantowego usuwania układu chłonnego szyi po radiochemioterapii w zaawansowanym raku płaskonabłonkowym głowy i szyi – przegląd literatury

Zeszyty Naukowe WCO, Letters in Oncology Science Pub Date : 2014-01-01 DOI: 10.1016/j.onko.2014.03.002

Anna Adamska, Anna Rucińska

{"title":"Rola adjuwantowego usuwania układu chłonnego szyi po radiochemioterapii w zaawansowanym raku płaskonabłonkowym głowy i szyi – przegląd literatury","authors":"Anna Adamska, Anna Rucińska","doi":"10.1016/j.onko.2014.03.002","DOIUrl":"10.1016/j.onko.2014.03.002","url":null,"abstract":"<div><p>Chemoradiation (CT-RT) is currently a recognised standard of treatment for advanced squamous cell carcinoma of the head and neck. An adjuvant neck node dissection remains a controversial issue. Some authors suggest that surgery should be proposed for all patients with advanced N-stage at diagnosis regardless of the response to organ-preservation protocol which is CT-RT. Others recommend that the decision on surgery should be based on the clinical assessment of the response to radical CT-RT. Both strategies are characterised by a comparable regional control and progression free survival rates. They differ, however, in the quantity and quality of induced complications, and generate different costs. Therefore, an intensive search for (clinical or radiological) predictors to treatment response is needed to identify a specific group of patients who would benefit from adding neck dissection and without exposing complete responders to unnecessary complications. In this respect, the use of PET-CT scanning has gained some interest in selecting patients appropriate for lymphatic surgery. This method, however, has been found to have some faults and limitations.</p></div>","PeriodicalId":101295,"journal":{"name":"Zeszyty Naukowe WCO, Letters in Oncology Science","volume":"11 1","pages":"Pages 7-14"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.onko.2014.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88603711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Nr 38] Psychoonkologia – rys historyczny

Zeszyty Naukowe WCO, Letters in Oncology Science Pub Date : 2013-11-01 DOI: 10.1016/j.onko.2013.09.039

Teresa Świrydowicz

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[Nr 112] Rekonstrukcja górnego odcinka przewodu pokarmowego u chorej po operacji całkowitego usunięcia krtani z częścią szyjną przełyku – opis przypadku

Zeszyty Naukowe WCO, Letters in Oncology Science Pub Date : 2013-11-01 DOI: 10.1016/J.ONKO.2013.09.113

Jakub Pazdrowski, P. Golusiński, W. Golusiński

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