Anuj Kumar , Sarbani Ghosh Laskar , Katherine Wakeham , Kamal Akbarov , Jai Prakash Agarwal
{"title":"Personal view: Understanding and addressing gaps between randomized controlled trials and real-world evidence in oncology","authors":"Anuj Kumar , Sarbani Ghosh Laskar , Katherine Wakeham , Kamal Akbarov , Jai Prakash Agarwal","doi":"10.1016/j.rcro.2025.100289","DOIUrl":"10.1016/j.rcro.2025.100289","url":null,"abstract":"","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100289"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nidhi Kishore Agrawal, Sapna Abdul Rahim, Alpna Jain
{"title":"Primary unilateral breast angiosarcoma in adolescence","authors":"Nidhi Kishore Agrawal, Sapna Abdul Rahim, Alpna Jain","doi":"10.1016/j.rcro.2025.100288","DOIUrl":"10.1016/j.rcro.2025.100288","url":null,"abstract":"<div><div>Primary breast angiosarcoma is a rare soft tissue malignancy of vascular origin, particularly in young patients. Here, we present the case of an 18-year-old autistic female with Addison's disease who developed a rapidly enlarging unilateral breast mass initially diagnosed as an abscess. Despite treatment, the lesion progressed to chest wall and lymph node metastases within three months. This case emphasizes the importance of including malignancy in the differential diagnosis of atypical breast presentations, even in young patients, and highlights the diagnostic and therapeutic challenges associated with this aggressive tumour.</div></div>","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100288"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The ability of artificial intelligence to correctly identify acute haemorrhage in A&E patients on a non-contrast CT head: a review of false positives in Brainomix in a single centre","authors":"Aisha Hameed, Lois Aikins, Garryck Tan","doi":"10.1016/j.rcro.2025.100238","DOIUrl":"10.1016/j.rcro.2025.100238","url":null,"abstract":"","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100238"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143336596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Technology-enhanced learning with PGVLE: standardising neuroradiology training through the NODE initiative","authors":"Nitin Menon , Adam Thomas , Usman Ahmed","doi":"10.1016/j.rcro.2025.100258","DOIUrl":"10.1016/j.rcro.2025.100258","url":null,"abstract":"","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100258"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143297854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ernest Montana , Constantinus F. Buckens , Geraldine Dean , Susan Cheng-Shelmerdine , Stavroula Kyriaza , Gareth Davies
{"title":"Large language models are well suited for data-mining free-text radiology referrals from multiple sources: Let chat-GPT do the heavy lifting for you","authors":"Ernest Montana , Constantinus F. Buckens , Geraldine Dean , Susan Cheng-Shelmerdine , Stavroula Kyriaza , Gareth Davies","doi":"10.1016/j.rcro.2024.100201","DOIUrl":"10.1016/j.rcro.2024.100201","url":null,"abstract":"","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100201"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143179328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In the tutelage of ChatGPT: Assessing AI's capability to simplify radiology physics, a bilingual approach","authors":"Shardul Tyagi , Namrita Sachdev","doi":"10.1016/j.rcro.2024.100203","DOIUrl":"10.1016/j.rcro.2024.100203","url":null,"abstract":"","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100203"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143180138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiogenomic AI model predicts immune status in IDH wildtype glioblastoma: PRECISE-GBM study","authors":"Prajwal Ghimire, Marc Modat, Thomas Booth","doi":"10.1016/j.rcro.2024.100234","DOIUrl":"10.1016/j.rcro.2024.100234","url":null,"abstract":"","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100234"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143181482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Grace Kusumawidjaja , Syazana Mohamed Rashid , Thamizhisai Swaminathan , Zubin Master , Sze Huey Tan , Kevin Lee Min Chua , Fang Yue Yong , Kheng-Wei Yeoh
{"title":"Analysis of modern versus conventional radiotherapy techniques for gastric mucosa-associated lymphoid tissue (MALT) lymphoma","authors":"Grace Kusumawidjaja , Syazana Mohamed Rashid , Thamizhisai Swaminathan , Zubin Master , Sze Huey Tan , Kevin Lee Min Chua , Fang Yue Yong , Kheng-Wei Yeoh","doi":"10.1016/j.rcro.2025.100346","DOIUrl":"10.1016/j.rcro.2025.100346","url":null,"abstract":"<div><h3>Background and purpose</h3><div>Localized MALT (gMALT) lymphoma patients are primarily treated with radiotherapy (RT). Considering the different resource capabilities of departments globally, the incremental benefits with modern techniques has not yet been determined. Here we report dosimetric differences of current RT techniques.</div></div><div><h3>Materials and methods</h3><div>Twelve stage IE gMALT patients treated with RT between January 2011 and December 2016 were analyzed. RT planning were recreated for conventional (parallel-opposed, 3D-conformal-RT [3D], 3D-field-in-field [3DFIF]) and modern techniques (volumetric-modulated-arc-therapy [VMAT], intensity-modulated-RT, helical tomotherapy). Prior to treatment, patients fasted for 4 h. RT prescription dose was 30Gy in 20 fractions. Planning target volume (PTV) was defined as entire stomach with 1–2 cm isometric expansion. OARs (heart, kidneys, liver and cord) constraints were determined according to QUANTEC. Dosimetric data were summarized and compared.</div></div><div><h3>Results</h3><div>Median age was 65.5y (range, 50–78). At the median follow-up of 70.5 m all patients are alive with no disease relapse post-RT nor any grade ≥3 treatment side effects. Compared to conventional RT, modern RT techniques were similar in providing excellent dose distribution and all OARs sparing. Specific to PTV coverage, VMAT was superior compared to 3DFIF (p < 0.001) and 3D (p ≤ 0.008). However, PTV coverage improvement was not clinically relevant. In OAR sparing, VMAT had better heart-sparing effect than 3DFIF (p < 0.01) or 3D (P < 0.01). Specific to kidneys, all 3 techniques fulfilled constraints. All techniques fulfilled cord and liver constraints.</div></div><div><h3>Conclusion</h3><div>While modern RT techniques offer significant advantages, conventional techniques were sufficient to achieve good target volume coverage and reduce dose to the OARs in most patients. Some individuals, such as those with challenging anatomy, may be good candidates for modern approaches. The insights gained from this study can be used to optimize 3D or 3D field-in-field (3DFIF) plans for these patients. With recent data showing good outcomes with lower RT doses, it also would be important to investigate the utility of advanced techniques globally.</div></div>","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100346"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144084370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deep learning for Radiotherapy Autosegmentation Workflow (DRAW): System engineering and preliminary experience with an autosegmentation solution built using open-source software","authors":"Santam Chakraborty , Indranil Mallick , Sandip Dutta , Jayanta Mukhopadhyay , Surajit Kundu , Sougata Maity , Oindrila Roychowdhury , Moses Arunsingh , Tapesh Bhattacharyya , Sanjoy Chatterjee , Rimpa Basu Achari","doi":"10.1016/j.rcro.2024.100210","DOIUrl":"10.1016/j.rcro.2024.100210","url":null,"abstract":"","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100210"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143175925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Smart reporting: ChatGPT vs radiologists in MSK knee MRI analysis","authors":"Vikash Rustagi , Sakina Naqvi","doi":"10.1016/j.rcro.2025.100247","DOIUrl":"10.1016/j.rcro.2025.100247","url":null,"abstract":"","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100247"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143319091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}