The Journal of Trace Elements in Experimental Medicine最新文献

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Iron
The Journal of Trace Elements in Experimental Medicine Pub Date : 2001-05-01 DOI: 10.1002/jtra.1014
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引用次数: 0
Copper
The Journal of Trace Elements in Experimental Medicine Pub Date : 2001-05-01 DOI: 10.1002/jtra.1024
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引用次数: 0
Essentiality and toxicity of trace elements: Principles and methods for assessment of risk from human exposure to essential trace elements 微量元素的重要性和毒性:人体接触微量元素风险评估的原则和方法
The Journal of Trace Elements in Experimental Medicine Pub Date : 2001-05-01 DOI: 10.1002/jtra.1038
G. Nordberg, B. Sandström, G. Becking, R.A. Goyer
{"title":"Essentiality and toxicity of trace elements: Principles and methods for assessment of risk from human exposure to essential trace elements","authors":"G. Nordberg,&nbsp;B. Sandström,&nbsp;G. Becking,&nbsp;R.A. Goyer","doi":"10.1002/jtra.1038","DOIUrl":"10.1002/jtra.1038","url":null,"abstract":"<p>Recommendations aimed at protecting the public from toxicity of essential elements have been developed separately from those recommendations aimed at protection from deficiency. Because of the uncertainties involved in evaluations, these recommendations have sometimes been in conflict, emphasizing the need for a new approach including a balanced consideration of nutritional as well as toxicological data.</p><p>In developing these new principles of evaluation, some basic concepts based on interindividual variability in sensitivity to deficiency and toxicity must be considered. Such variation translates into one interval of (low) daily intakes, at which there is risk of developing deficiency, and another interval of (high) dietary intakes, at which toxicity may occur. In most instances there is a third set of intakes in between, which represents the acceptable range of oral intakes (AROI) in which no adverse effects occur. It must be noted, however, that such a range cannot be found that protects all persons from adverse effects. Those persons with genetically determined sensitivity may require higher intakes to avoid deficiency, or lower intakes to avoid toxicity than those defined by AROI. AROI is defined as protecting 95% of an unselected human population from even minimal adverse effects of deficiency or toxicity. J. Trace Elem. Exp. Med. 13:141–153, 2000.</p>","PeriodicalId":101243,"journal":{"name":"The Journal of Trace Elements in Experimental Medicine","volume":"14 2","pages":"261-273"},"PeriodicalIF":0.0,"publicationDate":"2001-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/jtra.1038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89140735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Iron: Seminal publications of the twentieth century—Haemochromatosis 铁:20世纪的开创性出版物-血色素沉着病
The Journal of Trace Elements in Experimental Medicine Pub Date : 2001-05-01 DOI: 10.1002/jtra.1016
Marcel E. Conrad
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引用次数: 0
Zinc
The Journal of Trace Elements in Experimental Medicine Pub Date : 2001-05-01 DOI: 10.1002/jtra.1019
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引用次数: 0
Importance of the report “Syndrome of iron deficiency anemia, hepatosplenomegaly, hypogonadism, dwarfism and geophagia” 《缺铁性贫血、肝脾肿大、性腺功能减退、侏儒症、食土症综合征》报告的重要性
The Journal of Trace Elements in Experimental Medicine Pub Date : 2001-05-01 DOI: 10.1002/jtra.1021
Harold H. Sandstead
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引用次数: 3
Commentary: Selenium 评论:硒
The Journal of Trace Elements in Experimental Medicine Pub Date : 2001-05-01 DOI: 10.1002/jtra.1032
Philip Whanger
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引用次数: 1
Iodine
The Journal of Trace Elements in Experimental Medicine Pub Date : 2001-05-01 DOI: 10.1002/jtra.1035
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引用次数: 0
Commentary: Selenium 评论:硒
The Journal of Trace Elements in Experimental Medicine Pub Date : 2001-05-01 DOI: 10.1002/jtra.1034
Raymond F. Burk
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引用次数: 2
A special issue on landmark articles 关于里程碑文章的特刊
The Journal of Trace Elements in Experimental Medicine Pub Date : 2001-05-01 DOI: 10.1002/jtra.1013
Ananda S. Prasad MD, PhD, Monica Nordberg PhD, Patricia Ann Krause
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引用次数: 0
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