Surgical Oncology Insight最新文献

{"title":"Commentary on “Supporting the PACT Act: Top cancers diagnosed in young veterans who deployed to Iraq and Afghanistan”","authors":"Erin M. Bayley, Haley Moss, Akiko Chiba, Sarah Colonna, Karen M. Goldstein, Megan Shepherd-Banigan, Anna Jo Smith, Michael J. Kelley, Leah L. Zullig","doi":"10.1016/j.soi.2026.100215","DOIUrl":"10.1016/j.soi.2026.100215","url":null,"abstract":"","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100215"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146037954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between area deprivation index (ADI) and initial treatment among patients with desmoid tumors","authors":"Alexandra G. Lopez-Aguiar ,&nbsp;Menglin Xu ,&nbsp;Han Gil Kim ,&nbsp;David Liebner ,&nbsp;Valerie P. Grignol ,&nbsp;Gabriel Tinoco","doi":"10.1016/j.soi.2026.100216","DOIUrl":"10.1016/j.soi.2026.100216","url":null,"abstract":"<div><h3>Introduction</h3><div>Desmoid fibromatosis is a locally aggressive, non-metastasizing soft tissue tumor associated with substantial morbidity. Management has shifted away from routine surgical resection toward surveillance and systemic therapies. Socioeconomic disadvantage may influence treatment selection even among patients evaluated at tertiary referral centers. This study evaluated the association between neighborhood-level socioeconomic disadvantage, measured by the area deprivation index (ADI), and initial treatment strategy among patients with desmoid tumors.</div></div><div><h3>Methods</h3><div>Adults evaluated for desmoid fibromatosis at The Ohio State University between January 1, 2010, and January 1, 2021, were included in this retrospective cohort. Residential addresses were mapped to national ADI scores using the Neighborhood Atlas, and initial management was categorized as surgery, systemic therapy, or radiation. Associations between ADI and treatment selection were examined using prespecified univariate regression analyses.</div></div><div><h3>Results</h3><div>Among 151 patients, initial treatment included surgery (72 %), systemic therapy (24 %), or radiation (4 %). Patients residing in higher-ADI neighborhoods had significantly higher ADI scores when treated with systemic therapy compared with surgery (mean ADI 65 vs 50, P = 0.013), and higher ADI was associated with selection of systemic therapy rather than upfront surgery.</div></div><div><h3>Conclusion</h3><div>In this single-institution cohort, higher neighborhood socioeconomic disadvantage was associated with selection of non-surgical initial management for desmoid fibromatosis. These findings reflect treatment patterns during a transitional era in desmoid care and suggest that socioeconomic factors may influence management decisions even among patients accessing specialized care. Further multi-institutional studies in contemporary cohorts are needed to clarify how socioeconomic disadvantage affects treatment selection and outcomes.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100216"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Omission of sentinel lymph node biopsy in elderly patients with HR+ /HER2 − breast cancer: A population-based analysis from Taiwan","authors":"Chi-Cheng Huang ,&nbsp;Hsiu-Ying Ku ,&nbsp;Jun-Ping Shiau ,&nbsp;Fang-Ming Chen ,&nbsp;Ming-Feng Hou ,&nbsp;Tsang-Wu Liu ,&nbsp;Ling-Ming Tseng ,&nbsp;Hui-Ju Ch’ang","doi":"10.1016/j.soi.2026.100229","DOIUrl":"10.1016/j.soi.2026.100229","url":null,"abstract":"<div><div>The study evaluated whether omission of sentinel lymph node biopsy (SLNB) affects survival outcomes in elderly patients (≥70 years) with hormone receptor (HR)-positive and human epidermal growth factor receptor 2 (HER2)-negative, node-negative breast cancer. We hypothesized that omission of SLNB does not compromise cancer-specific survival in this population. We utilized data from the Taiwan Cancer Registry (TCR). From 2011–2020, we identified 5743 eligible HR+ /HER2-, cN0 breast cancer cases in patients aged ≥70 years. A total of 28.6 % (n = 1642) underwent surgery without a SLNB. Of those with a positive SLNB result (n = 805), 27 % (n = 218) were treated without further axillary lymph node dissection (ALND). In the multivariate analysis for patients aged ≥80 years, performing a SLNB did not significantly impact either cancer-specific survival (CSS) or overall survival (OS). Taking hormone therapy only as the baseline risk, the adjusted hazard ratio (aHR) for SLNB use versus no use was 1.03 for CSS and 1.18 for OS. Propensity score-matched CSS also supported the safe omission of SLNB for patients aged ≥80 years. For SLNB-negative cases, no significant difference in survival was found among the treatment combinations (endocrine alone and combinations of endocrine with surgery, radiotherapy, or chemotherapy). For SLNB-positive patients, the combination of hormone, chemo-, and radiotherapy was required to achieve CSS comparable to SLNB-negative patients. Omitting SLNB for patients aged 80 or older with clinically node-negative breast cancer is safe, confirming the potential for de-escalation of axillary surgery in this population.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100229"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between the primary colorectal tumor budding score and the histological growth pattern of peritoneal metastases: A pilot study","authors":"Mendhi Bouatrous ,&nbsp;Charif Khaled ,&nbsp;Pieter Demetter ,&nbsp;Peter Vermeulen ,&nbsp;Francesco Sclafani ,&nbsp;Alexandre El Kazzi ,&nbsp;Michel Moreau ,&nbsp;Gabriel Liberale","doi":"10.1016/j.soi.2026.100236","DOIUrl":"10.1016/j.soi.2026.100236","url":null,"abstract":"<div><h3>Background</h3><div>Tumor budding (TB) has recently emerged as a prognostic marker for primary colorectal cancer (CRC), and histological growth pattern (HGP) is a prognostic marker for colorectal liver metastases (LM) and peritoneal metastases (PM). The main objective of this study was to evaluate potential correlations between the TB score of a primary CRC and the HGP of PM from that CRC.</div></div><div><h3>Methods</h3><div>Monocentric, retrospective study including patients who underwent surgery for primary CRC with synchronous or metachronous PM requiring complete cytoreductive surgery (CRS). TB score and HGP were assessed from pathology slides and categorized as low, intermediate, and high TB score for the primary tumor (PT), and as dominant (&gt;50 %) pushing or infiltrating HGP for PM.</div></div><div><h3>Results</h3><div>Twenty-four patients were included in the study, 14 women and 10 men, with a median age of 67 years. Twelve patients (50.0 %) had low TB score (0–4 buds), 10 patients (41.7 %) had lymph node involvement (pN+), and 8 patients (33.3 %) had synchronous PM. Nine patients (37.5 %) had a dominant pushing HGP and 15 patients (62.5 %) a dominant infiltrating profile. There were no significant associations between the TB score of the primary CRC and the HGP of the PM.</div></div><div><h3>Conclusions</h3><div>No significant correlation was found between the TB score of the PT and the HGP of the PM. Consequently, this work suggests that patients with a high TB CRC do not have an increased likelihood of having PM with an infiltrative profile, despite both being poor prognostic factors.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100236"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elevated core body temperature during hyperthermic intraperitoneal chemotherapy does not impact postoperative outcomes","authors":"Judy Li ,&nbsp;Ryan Wang ,&nbsp;Joshua A. Leinwand ,&nbsp;Noah A. Cohen ,&nbsp;Umut Sarpel","doi":"10.1016/j.soi.2025.100200","DOIUrl":"10.1016/j.soi.2025.100200","url":null,"abstract":"<div><h3>Background</h3><div>Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is an important treatment modality in the management of peritoneal surface malignancies. The effect of elevated core body temperature (CBT) during HIPEC on clinical outcomes is unclear.</div></div><div><h3>Methods</h3><div>A retrospective review of patients who underwent HIPEC at a tertiary care institution between 2006 and 2019 with complete perfusion and anesthesia records was conducted. The cohort was stratified into two groups according to mean CBT recorded during HIPEC. Elevated CBT was defined as core temperature ≥ 38 °C. A supplemental analysis was performed with a higher threshold of 39.5 °C.</div></div><div><h3>Results</h3><div>147 patients were identified, with 100 (68 %) having elevated CBTs during HIPEC. Baseline characteristics were similar. The majority had peritoneal disease of colorectal and appendiceal origin. Peritoneal cancer index (PCI) scores and operative characteristics were similar between groups. HIPEC parameters such as perfusion flow rates, and inflow and outflow temperatures were comparable. Average CBT in both groups did not exceed 40 °. Postoperative course, 30-day complication rates and disease-free (median 7 months in normal CBT vs 18 months in elevated CBT, P = 0.116) and overall survival (median 50 months in normal CBT vs 76 months in elevated CBT, P = 0.569) were similar.</div></div><div><h3>Conclusion</h3><div>Despite inflow temperatures of 43 °C, average CBT did not exceed 40 °C, demonstrating that HIPEC does not cause equivalent systemic hyperthermia. Patients experiencing elevated CBT during HIPEC have similar postoperative morbidity, mortality, and oncologic outcomes compared to those with normal CBT, suggesting that patients may be more tolerant of hyperthermia than previously reported.</div></div><div><h3>Synopsis</h3><div>Research about hyperthermic intraperitoneal chemotherapy (HIPEC) has focused previously on chemotherapy agents and perfusion parameters, but there is a lack of data investigating the effect of core body temperatures (CBT) on clinical outcomes. The majority of patients have an elevated CBT during HIPEC, but on average do not exceed 40 °C. These patients have similar postoperative and oncologic outcomes, suggesting that patients are more tolerant of elevated CBTs than previously reported.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100200"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145694611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic anatomical left hepatectomy with enbloc caudate resection for intrahepatic cholangiocarcinoma","authors":"Bhavya Bansal ,&nbsp;Parisa Yazdankhan Kenary ,&nbsp;Sharona Ross ,&nbsp;Iswanto Sucandy","doi":"10.1016/j.soi.2025.100207","DOIUrl":"10.1016/j.soi.2025.100207","url":null,"abstract":"<div><h3>Introduction</h3><div>Minimally invasive robotic technique is gaining popularity due to its technical advantages when compared with conventional laparoscopy. Major hepatic lobectomy, however, remains a technically demanding procedure and requires extensive training to ensure safety and efficacy, especially when undertaken using minimally invasive approach.<span><span>1</span></span>, <span><span>2</span></span>, <span><span>3</span></span>, <span><span>4</span></span> With focus on robotic surgery techniques, in this video we describe our standardized technical approach of robotic anatomical left hepatectomy with enbloc caudate lobe resection.</div></div><div><h3>Methods</h3><div>A 78-year-old man presented with a caudate lobe cholangiocarcinoma infiltrating the caudate lobe and dorsal aspect of segment 4 with a very close proximity to the base of umbilical fissure. No evidence of extrahepatic metastasis is seen. Left anatomical hepatic lobectomy enbloc with caudate resection is needed to oncologically remove the tumor, in addition to radical portal abdominal lymphadenectomy. Technical operative steps are shown in the multimedia video.</div></div><div><h3>Results</h3><div>Total operative time was 270 min, with an estimated blood loss of 100 mL. The patient had an uneventful postoperative recovery and he was discharged on postoperative day 6. Pathologic evaluation revealed a 6.7 cm moderately differentiated cholangiocarcinoma with negative margins.</div></div><div><h3>Conclusion</h3><div>This case highlights the safety, feasibility, and technical steps of robotic anatomical left hepatic lobectomy with enbloc caudate resection.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100207"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to ‘Collateral vessel formation affects long-term patency of artificial vessels: Insights from 60 cases of superior vena cava reconstruction combined with thymic tumor resection’ [Surg Oncol Insight 2 (2) (2025) 100151]","authors":"Yongqiang Ao ,&nbsp;Jiahao Jiang ,&nbsp;Shuai Wang ,&nbsp;Jian Gao ,&nbsp;Yuansheng Zheng ,&nbsp;Lijie Tan ,&nbsp;Junzhen Liu ,&nbsp;Jianyong Ding","doi":"10.1016/j.soi.2026.100232","DOIUrl":"10.1016/j.soi.2026.100232","url":null,"abstract":"","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100232"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of MRI-fluoroscopic guided microwave ablation of small subdiaphragmatic and pericardial liver tumors","authors":"Daniel Markus Düx ,&nbsp;Bennet Hensen ,&nbsp;Julian Glandorf ,&nbsp;Simon Schröer ,&nbsp;Othmar Belker ,&nbsp;Dominik Horstmann ,&nbsp;Moritz Gutt ,&nbsp;Kristina Imeen Ringe ,&nbsp;Frank Wacker ,&nbsp;Marcel Gutberlet","doi":"10.1016/j.soi.2025.100206","DOIUrl":"10.1016/j.soi.2025.100206","url":null,"abstract":"<div><h3>Purpose</h3><div>Evaluating safety and efficacy of magnetic resonance-guided microwave ablation (MRgMWA) for small subdiaphragmatic and pericardial hepatic malignancies (HM).</div></div><div><h3>Methods</h3><div>This single-center study retrospectively reviewed MRgMWA for lesions ≤ 2 cm within 1 cm of the diaphragm from 02/2017–05/2025. Complications were classified according to “Cardiovascular and Interventional Radiological Society of Europe” guidelines. Technical efficacy, local tumor progression (LTP), local tumor recurrence (LTR), non-target progression (NTP), and time to progression were assessed. Data is presented as mean ± standard deviation.</div></div><div><h3>Results</h3><div>Twenty-three patients (64.8 ± 10.2 years; 15 males, 8 females) with 25 HM (17 hepatocellular carcinoma, 1 cholangiocarcinoma, 7 metastases) were treated. Lesion size was 13.1 ± 4.4 mm, with proximity to diaphragm of 3.1 ± 3.2 mm. Total procedure duration was 2 h 14 min ± 51 min. The complication rate was 33.3 %, including pain (N = 3), fever (N = 2), hematoma (N = 1), bilioma (N = 1), and reactive cholecystitis (N = 1). All complications resolved - two with pain medication and one with antibiotics. Technical efficacy was 100 %. No tumor recurrence was observed at ablation sites (LTP and LTR = 0 %) at 32.5 ± 29.0 months, but one seeding metastasis occurred. NTP occurred in 14 patients (60.9 %) at 13.6 ± 10.8 months. Three patients died 7, 32 and 48 months post-ablation. One patient underwent liver transplantation post-ablation.</div></div><div><h3>Conclusions</h3><div>MRgMWA for small subdiaphragmatic and pericardial HM may be safe and effective, demonstrating no LTR at 32.5 ± 29.0 months follow-up.</div></div><div><h3>Synopsis</h3><div>This study highlights the potential of MR-guided microwave ablation as minimally-invasive treatment option for small subdiaphragmatic (N = 20) or pericardial (N = 5) liver tumors. Complications seem relatively low compared to existing studies with excellent local tumor control.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100206"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145840592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Society of surgical oncology medical student & trainee primer for non-HPB GI oncology","authors":"Hideo Takahashi ,&nbsp;Micah J. Brainerd ,&nbsp;Natalie Bath ,&nbsp;Brian K. Sparkman ,&nbsp;Kelly L. Koch ,&nbsp;Ricardo J. Bello ,&nbsp;Raja R. Narayan ,&nbsp;Marissa K. Boyle ,&nbsp;Julia M. Selfridge ,&nbsp;Christopher P. Childers ,&nbsp;on behalf of the Fellows and Young Attendings Committee of the Society of Surgical Oncology (SSO)","doi":"10.1016/j.soi.2025.100201","DOIUrl":"10.1016/j.soi.2025.100201","url":null,"abstract":"<div><div>The goal of this primer is to educate the future generation of surgeons and prepare trainees for their clinical rotations in the operating room and with patient care. This primer will introduce medical students and trainees to the diagnosis and management of benign and malignant non-hepatopancreatobiliary (HPB) gastrointestinal (GI) oncology for their surgical oncology rotations.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100201"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145694619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Society of surgical oncology medical student & trainee primer for skin, soft tissue, and endocrine surgical oncology","authors":"Danielle Graham ,&nbsp;Andrew Francis ,&nbsp;Micah Brainerd ,&nbsp;Ian Garbarine ,&nbsp;Nicole Rademacher ,&nbsp;Kelly L. Koch ,&nbsp;Julia M. Selfridge ,&nbsp;Christopher P. Childers ,&nbsp;Marissa K. Boyle ,&nbsp;Brian K. Sparkman ,&nbsp;Natalie M. Bath ,&nbsp;on behalf of the Fellows and Young Attendings Committee of the Society of Surgical Oncology (SSO)","doi":"10.1016/j.soi.2025.100203","DOIUrl":"10.1016/j.soi.2025.100203","url":null,"abstract":"<div><div>The goal of this primer is to educate the future generation of surgeons and prepare trainees for their clinical rotations in the operating room and in the clinic. This primer will introduce medical students and trainees to the diagnosis and management of skin, soft tissue, and endocrines cancers for their surgical oncology rotations.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100203"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}