Surgical Oncology Insight最新文献

{"title":"Evaluating handgrip strength as a predictor of postoperative outcomes in pancreatic resection","authors":"Erin Kim ,&nbsp;Catherine Evans ,&nbsp;Sahil Tolia ,&nbsp;Andrew Vastardis ,&nbsp;David Gandham ,&nbsp;Mario Pallazola ,&nbsp;Benjamin D. Ferguson","doi":"10.1016/j.soi.2026.100235","DOIUrl":"10.1016/j.soi.2026.100235","url":null,"abstract":"<div><h3>Introduction</h3><div>Handgrip strength (HGS) is an inexpensive bedside test that serves as a proxy for muscle mass and nutritional reserve, factors relevant to preoperative risk stratification. While HGS has been linked to postoperative outcomes in other surgical populations, its role in pancreatic resection remains unclear. We evaluated associations between preoperative HGS, length of stay (LOS), and clinically relevant postoperative pancreatic fistula (CR-POPF).</div></div><div><h3>Methods</h3><div>Patients undergoing pancreatic resection at a single academic center (August 2023–July 2024) were prospectively enrolled. Preoperative HGS was measured with a Jamar dynamometer, and maximum dominant-hand values were categorized into age- and sex-adjusted quartiles. LOS, defined as cumulative inpatient days within 90 days, was compared across quartiles using the Kruskal–Wallis test. In pancreatoduodenectomy patients, multivariable logistic regression assessed the relationship between HGS quartile and CR-POPF, defined by International Study Group on Pancreatic Surgery (ISGPS) criteria (Grades B–C), adjusting for age, sex, and body mass index (BMI).</div></div><div><h3>Results</h3><div>The cohort included 83 patients (median age, 64 years; 49% female). LOS differed significantly across HGS quartiles (χ²=11.23; P = .01). Among 50 pancreatoduodenectomy patients, higher HGS quartiles were associated with modestly increased odds of CR-POPF, though this did not reach statistical significance (odds ratio, 1.22; P = .56).</div></div><div><h3>Conclusion</h3><div>HGS may complement existing anatomic predictors to improve preoperative risk stratification in pancreatic surgery.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100235"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency and clarity of surgical goals for tumor resection in advanced soft tissue sarcoma","authors":"Julia H. Song ,&nbsp;Mark Fairweather ,&nbsp;Jiping Wang ,&nbsp;Sophia McKinley ,&nbsp;Chandrajit P. Raut ,&nbsp;Jennifer W. Mack ,&nbsp;Elizabeth J. Lilley","doi":"10.1016/j.soi.2026.100233","DOIUrl":"10.1016/j.soi.2026.100233","url":null,"abstract":"<div><div>Surgery for advanced soft tissue sarcoma patients is often non-curative but may offer palliative benefits. Clearly stating how surgery may help patients live longer and/or improve their quality of life is essential to support informed decision-making. However, the frequency of documentation of surgical goals in medical records is unknown. We conducted a retrospective cohort study among patients ≥ 18 years old who underwent tumor resection for any site of soft tissue sarcoma from March 2024 to February 2025 at two academic medical centers. Advanced soft tissue sarcoma was defined as recurrent or metastatic disease. Preoperative notes were abstracted and categorized based on patient-centered surgical goals, which included prolonging life, relieving symptoms, preserving function, and diagnosing disease. Among 291 patients, 103 (35.5%) had advanced disease, only 31 of whom (30.1%) had a documented patient-centered surgical goal. Records for an additional 27 (26.2%) referenced cancer control without a clear patient-centered benefit, and 45 (43.7%) had no goal documented. These findings suggest the need to improve documentation of surgical goals for advanced sarcoma.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100233"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Society of surgical oncology medical student & trainee primer for hepatopancreatobiliary surgical oncology","authors":"Lily V. Saadat ,&nbsp;Bridget Kelly ,&nbsp;Micah J. Brainerd ,&nbsp;Marissa K. Boyle ,&nbsp;Brian K. Sparkman ,&nbsp;Kelly L. Koch ,&nbsp;Julia M. Selfridge ,&nbsp;Christopher P. Childers ,&nbsp;Robin Schmitz ,&nbsp;on behalf of the Fellows and Young Attendings Committee of the Society of Surgical Oncology (SSO)","doi":"10.1016/j.soi.2025.100202","DOIUrl":"10.1016/j.soi.2025.100202","url":null,"abstract":"<div><div>The goal of this primer is to educate the future generation of surgeons and prepare trainees for their clinical rotations in the operating room and with patient care. This primer will introduce medical students and trainees to the diagnosis and management of benign and malignant hepatopancreatobiliary (HPB) oncology for their surgical oncology rotations.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100202"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145694612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative carcinoid crisis in NET operations – Eluding Dogma with current understanding","authors":"Lucas W. Meuchel ,&nbsp;Rodney F. Pommier","doi":"10.1016/j.soi.2025.100198","DOIUrl":"10.1016/j.soi.2025.100198","url":null,"abstract":"","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100198"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145646073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Size of thyroid cancers does not correlate well with pre-operative thyroid nodule size on ultrasound","authors":"Adam Awe ,&nbsp;Chris B. Agala ,&nbsp;Anne Worth ,&nbsp;Ellie R. Lee ,&nbsp;Susan Maygarden ,&nbsp;Jen Jen Yeh","doi":"10.1016/j.soi.2025.100204","DOIUrl":"10.1016/j.soi.2025.100204","url":null,"abstract":"<div><h3>Introduction</h3><div>Pre-operative thyroid ultrasound (TUS) helps risk-stratify patients with thyroid nodules. We evaluated the association between TUS size, pathologic papillary thyroid cancer (PTC) size, and extent of surgery pursued.</div></div><div><h3>Methods</h3><div>A single-institution retrospective analysis was performed on patients &gt; 18 years of age with a pre-operative TUS from 2017 to 2022. Size comparisons were assessed using intra-class correlation (ICC).</div></div><div><h3>Results</h3><div>In total, 252 patients with 261 nodules were included. Two-hundred and twenty-one (84.7 %) nodules were PTC. The average maximum diameter of nodules was 0.77 cm (+/- 0.14 cm) on TUS and 1.40 cm (+/- 1.84 cm) on pathology for PTC &lt; 1 cm (p-value 0.31); ICC 0.0. The average maximum diameter of nodules was 2.03 cm (+/- 0.78 cm) on TUS and 1.67 cm (+/- 1.13 cm) on pathology for PTC 1 – 4 cm (p = 0.001); ICC 0.30 (95 % CI 0.15 – 0.46). The average maximum diameter of nodules was 5.29 cm (+/- 1.21 cm) on TUS and 3.58 cm (+/- 2.36 cm) on pathology for PTC &gt; 4 cm (p &lt; 0.001); ICC 0.05 (95 % CI - 0.40 – 0.51). Fifteen patients (45.5 %) with a TUS nodule &gt; 4 cm and pathological PTC less than or equal to 4 cm underwent a total thyroidectomy.</div></div><div><h3>Conclusions</h3><div>Pre-operative TUS of PTC &gt; 1 cm overestimated the pathologic size of PTC. Nearly half of patients with a TUS nodule &gt; 4 cm with pathologic PTC less than or equal to 4 cm underwent a total thyroidectomy. The size of nodules on pre-operative TUS should not dictate extent of thyroid resection alone.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100204"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Military insurance and melanoma outcomes in the national cancer database","authors":"R. Connor Chick ,&nbsp;Taylor P. Williams ,&nbsp;Robert W. Krell ,&nbsp;Hayley Dunlop ,&nbsp;Andrew Peachman ,&nbsp;Carlo M. Contreras ,&nbsp;Erin E. Burke ,&nbsp;Ryan Heslin ,&nbsp;Alex C. Kim ,&nbsp;Joal D. Beane","doi":"10.1016/j.soi.2026.100230","DOIUrl":"10.1016/j.soi.2026.100230","url":null,"abstract":"<div><h3>Introduction</h3><div>Melanoma is one of the most common cancers among military servicemembers and veterans. These individuals are increasingly required to seek cancer care in civilian settings. The aim of this study is to examine treatment patterns and outcomes among MB with melanoma and explore the influence of demographic or treatment differences on outcomes.</div></div><div><h3>Methods</h3><div>Using the National Cancer Database, patients age &lt; 65 with stage I-IV cutaneous melanoma with private (PI) or Other Government insurance (i.e. MB), no prior malignancies, and Charlson-Deyo score &lt; 3 were included. Overall survival (OS) was evaluated using Kaplan-Meier estimates and multivariate Cox proportional hazards models. Propensity score matching (PSM) was performed and survival analyses were repeated.</div></div><div><h3>Results</h3><div>Of 110,246 patients meeting inclusion criteria, 2009 were MB. MB were more likely than PI to be male, live in lower income areas, present at later stages, have fragmented care, travel further, and have a treatment delay &gt; 33 days (all p &lt; 0.001). MB was an independent predictor of stage III/IV at diagnosis (OR 1.38, p &lt; 0.001). 5-year OS was worse for MB compared with PI (85.9 % vs. 90.3 %, p &lt; 0.001). After adjusting for demographic and treatment variables, MB remained an independent predictor of reduced OS (HR 1.39, p &lt; 0.001). There was no difference in OS between MB and PI in the PSM analysis.</div></div><div><h3>Conclusions</h3><div>MB with cutaneous melanoma have significantly worse OS compared with PI. MB have more advanced stage presentation, care fragmentation, distance traveled, and treatment delay. Despite universal insurance coverage, MB with melanoma face additional challenges when treated outside federal facilities.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100230"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging the communication gap in foregut cancer: A qualitative exploration of patient and caregiver perspectives","authors":"Ioannis Liapis ,&nbsp;Jaspinder S. Sanghera ,&nbsp;Katie West ,&nbsp;Rida Ahmad ,&nbsp;Ahmed Abdalla ,&nbsp;Larry Hearld ,&nbsp;Martin J. Heslin ,&nbsp;Smita Bhatia ,&nbsp;Krista Mehari ,&nbsp;Annabelle L. Fonseca","doi":"10.1016/j.soi.2026.100238","DOIUrl":"10.1016/j.soi.2026.100238","url":null,"abstract":"<div><h3>Background</h3><div>Effective communication between patients, caregivers and the healthcare team is essential in foregut cancer care, where treatment often involves complex, high-risk decisions. Despite its importance, patient and caregiver perspectives on communication remain underexplored, particularly in underserved populations. This study aims to identify barriers and facilitators to communication from the perspectives of patients with foregut cancer and their caregivers.</div></div><div><h3>Study design</h3><div>This qualitative study involved semi-structured interviews at a safety-net and tertiary care center in the Southeastern United States. Interviews were recorded, transcribed, and qualitatively analyzed using inductive thematic and content analysis with NVivo 14 software. Intercoder agreement exceeded 90%. The study adhered to consolidated criteria for reporting qualitative research (COREQ).</div></div><div><h3>Results</h3><div>Forty-five individuals (30 patients, 15 caregivers) participated. Four key communication barriers were identified: (1) information overload and lack of clarity, (2) lack of clear expectation setting regarding prognosis and treatment impact, (3) lack of acknowledgement of patient or caregiver concerns, and (4) perceived inconsistencies in communication among providers. Five facilitators were described: (1) clear explanations using accessible language, (2) written or visual materials, (3) feeling heard, (4) opportunities to voice personal goals and concerns, and (5) presentation of treatment options and alternatives.</div></div><div><h3>Conclusion</h3><div>Patients with foregut cancer and their caregivers face significant communication challenges that may impact trust, decision-making and satisfaction. Clear, empathetic and consistent communication that integrates patient goals and clarifies expectations is crucial to enhance quality of care and support shared decision-making. Insights gained will inform strategies to enhance communication and improve patient-centered care.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100238"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic anatomical right hepatectomy for metastatic clear cell carcinoma. Standardized approach using robotic platform","authors":"Bhavya Bansal ,&nbsp;Ahmed Younos ,&nbsp;Sharona Ross ,&nbsp;Iswanto Sucandy","doi":"10.1016/j.soi.2025.100205","DOIUrl":"10.1016/j.soi.2025.100205","url":null,"abstract":"<div><h3>Introduction</h3><div>Minimally invasive robotic technique is gaining popularity due to its technical advantages when compared with conventional laparoscopy. Minimally invasive major hepatic lobectomy, especially for the right side, however, remains a technically demanding procedure and requires extensive training to ensure safety and efficacy.<span><span>1</span></span>, <span><span>2</span></span>, <span><span>3</span></span>, <span><span>4</span></span> Herein, we describe our standardized technical approach for anatomical right hepatectomy using robotic platform.</div></div><div><h3>Methods</h3><div>An 81-year-old woman presented with a single 9 cm urothelial carcinoma liver metastasis to the right hepatic lobe. PET scan shows a large-sized hypermetabolic tumor with no evidence of other lesion or extrahepatic disease. After confirmation of tumor resectability, a right anatomical hepatic lobectomy is needed to gain oncological clearance. Hepatic inflow control was obtained by ligation of right hepatic artery and portal vein. Detailed technical operative steps are shown in the multimedia video attached to this paper.</div></div><div><h3>Results</h3><div>Total operative time was 240 min, with an estimated blood loss of 75 mL. The patient had an uneventful postoperative recovery and she was discharged on postoperative day 4. Pathologic evaluation revealed a 9.0 cm metastatic urothelial carcinoma with negative resection margins. Currently, she is two years from the operation without any evidence of disease recurrence.</div></div><div><h3>Conclusion</h3><div>This video highlights safe and effective practical steps in performing robotic anatomical right hepatic lobectomy.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100205"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145749875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional differences in surgical strategies for peritoneal metastases based on various perspectives on oligometastases","authors":"Toshiyuki Kitai,&nbsp;Kenya Yamanaka,&nbsp;Ben Sasaki,&nbsp;Akie Tani,&nbsp;Yusuke Mishima,&nbsp;Takahito Omine,&nbsp;Makoto Kurimoto,&nbsp;Yuki Mochida,&nbsp;Masaki Tani,&nbsp;Kosuke Toda,&nbsp;Takefumi Yazawa,&nbsp;Hidenori Ohe,&nbsp;Masahiro Yamada","doi":"10.1016/j.soi.2026.100231","DOIUrl":"10.1016/j.soi.2026.100231","url":null,"abstract":"<div><div>Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) has become a treatment option for peritoneal metastases (PM); however, it is not performed as widely in Asian countries, including Japan, as in Western countries. This regional disparity may be due to various perspectives on oligometastatic disease (OMD). In this review, we searched literature on surgical management for PM to investigate differential perspectives on OMD in each region. Gastric cancer: Two surgical strategies are employed: intraperitoneal chemotherapy (IPC) + gastrectomy in Asian countries and CRS/HIPEC in Western countries. The former requires the negative conversion of cytology and the disappearance of PM as indication criteria for surgery. The latter requires no progression. The IPC+gastrectomy strategy is based on induced OMD, and the CRS/HIPEC is on genuine OMD. Colorectal cancer: Japanese study groups recommend R0 resection for PM adjacent to the primary tumor or limited PM to the distant peritoneum. On the other hand, Western study groups recommend complete CRS for PM with a peritoneal cancer index ≤17. Historical investigations revealed that the strategy for R0 resection was based on the contiguous theory and that for CRS on the spectrum theory. Ovarian cancer: Surgical strategies do not differ markedly. However, the optimal surgery rate is markedly lower in randomized controlled trial from Japan than in others. Indications for radical surgery are more restrictive, and the roles of perioperative chemotherapy are more strongly emphasized in Japan than in Western countries because Japanese study groups are less likely to regard PM as OMD than Western study groups.</div></div><div><h3>Synopsis</h3><div>There are regional differences in the surgical management of peritoneal metastases between Japan and Western countries because Japanese study groups are less likely to regard PM as OMD than Western study groups.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100231"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival outcomes after standard breast conserving surgery versus oncoplastic breast conserving surgery in breast cancer patients: A multicenter real-world evidence cohort study","authors":"Anne Dominique Nascimento Lima ,&nbsp;Eduardo Camargo Millen ,&nbsp;Francisco Pimentel Cavalcante ,&nbsp;Felipe Pereira Zerwes ,&nbsp;Andre Mattar ,&nbsp;Marcelo Antonini ,&nbsp;Maria Beatriz Paula Leite Kraft ,&nbsp;Alan Felipe Oliveira de Alencar ,&nbsp;Amanda de Queiroz Germano ,&nbsp;Daniele Pitanga Torres ,&nbsp;Eduarda Goulart Carneiro ,&nbsp;Carlos Frederico Freitas de Lima ,&nbsp;Natalia Polidorio Machado ,&nbsp;Renato Zocchio Torresan ,&nbsp;Fabrício Palermo Brenelli ,&nbsp;Martina Lichtenfels ,&nbsp;Isabele Small ,&nbsp;José Bines ,&nbsp;Antonio Luiz Frasson","doi":"10.1016/j.soi.2026.100239","DOIUrl":"10.1016/j.soi.2026.100239","url":null,"abstract":"<div><h3>Background</h3><div>Standard breast-conserving surgery (S-BCS) followed by radiotherapy is the preferred locoregional treatment for early-stage breast cancer but may result in unfavorable cosmetic outcomes, particularly in patients with small breasts. Oncoplastic breast-conserving surgery (O-BCS), allows wider resections while preserving breast shape. Although esthetic benefits are well established, data comparing long-term oncologic outcomes remain limited.</div></div><div><h3>Objective</h3><div>To compare oncologic outcomes between O-BCS and S-BCS in a multicenter real-world cohort.</div></div><div><h3>Methods</h3><div>This multicenter retrospective cohort study included women aged ≥ 18 years with stage 0–III breast cancer who underwent BCS followed by adjuvant radiotherapy between 2016 and 2022 at six institutions in Brazil. Survival outcomes were estimated using Kaplan–Meier methods and compared using multivariable Cox proportional hazards models adjusted for clinical stage.</div></div><div><h3>Results</h3><div>A total of 685 patients were included, of whom 550 (80.3%) underwent S-BCS and 135 (19.7%) O-BCS. Patients treated with O-BCS more frequently presented with advanced disease (≥IIB: 24.8% vs. 10.8%; <em>p</em> &lt; 0.001). No statistically significant differences in survival outcomes were observed. At 60 months, LRRFS was 90.0% for S-BCS and 96.3% for O-BCS (HR 0.35; <em>p</em> = 0.085), RFS was 89.7% and 96.1%(HR 0.36; <em>p</em> = 0.091), BCSS was 97.3% and 98% (HR 0.26; <em>p</em> = 0.198), and OS 96% and 97.3% (HR 0.53; <em>p</em> = 0.31) respectively.</div></div><div><h3>Conclusion</h3><div>In this multicenter real-world cohort, O_BCS achieved oncologic outcomes comparable to S-BCS despite being used in patients with more advanced disease, supporting its use as a breast-conserving strategy in appropriately selected patients.</div></div>","PeriodicalId":101191,"journal":{"name":"Surgical Oncology Insight","volume":"3 1","pages":"Article 100239"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}