{"title":"Cross-leg flap, alternative surgery for post traumatic soft tissue defect of ankle and foot","authors":"Fadlurrahman Manaf , Azmi Farhadi","doi":"10.1016/j.sycrs.2024.100074","DOIUrl":"10.1016/j.sycrs.2024.100074","url":null,"abstract":"<div><h3>Background</h3><div>Soft tissue defects that afflict the ankle and foot are mostly the result of trauma. Large wounds with soft tissue defects, especially in the ankle and foot, are a reconstructive challenge due to the lack of availability of local tissues and recipient vessels.</div></div><div><h3>Case Presentation</h3><div>We report a female with a crush injury of the right foot and a Lisfranc injury due to a motor vehicle accident. The patient had a soft tissue defect 20 × 10 cm2 with bone and tendon exposed. The patient had a fasciocutaneous flap from the posteromedial of the distal contralateral leg for soft tissue reconstruction. Both legs were stabilized with a cast. The cross-leg flap was separated from the donor site three weeks later, and K-Wire was removed. Flap evaluation was good, and the patient resumed normal gait and activity without any stiffness of joints related to the flap or cast.</div></div><div><h3>Discussion</h3><div>Reconstruction of soft tissue defects in the ankle and foot is a challenge for surgeons due to the paucity of local and regional tissues and associated vessel injuries. Cross-leg flap can be suitable alternative option. In this case, we use medially based fasciocutaneous perforator cross-leg flap, based on the posterior tibial artery perforators. Cross-leg flaps are less technically demanding, and the probability of reexploration is lower than in free flaps. The cross-leg flap has the disadvantage of prolonged immobilization and uncomfortable resting positions.</div></div><div><h3>Conclusion</h3><div>Cross-leg flap can be alternative solution for covering large soft tissue defects in ankle and foot with its advantages and disadvantages.</div></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"3 ","pages":"Article 100074"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Halil Ibrahim BULUT , Erhan OKAY , Tolga ONAY , Enes KANAY , Korhan OZKAN
{"title":"Innovative approaches to cage reconstructions in orthopedic limb surgery: Advances and insights with two cases","authors":"Halil Ibrahim BULUT , Erhan OKAY , Tolga ONAY , Enes KANAY , Korhan OZKAN","doi":"10.1016/j.sycrs.2024.100073","DOIUrl":"10.1016/j.sycrs.2024.100073","url":null,"abstract":"<div><h3>Background</h3><div>Limb tumors, though rare, pose significant challenges to surgical management due to their impact on limb function and quality of life. Effective treatment requires precise tumor resection alongside advanced reconstructive techniques to restore limb function, particularly in cases of compromised bone healing. Titanium cages, traditionally used in spinal surgeries, have recently gained attention for their potential in limb reconstruction within orthopedic oncology, offering a novel approach to managing complex bone defects.</div></div><div><h3>Case Presentation</h3><div>This retrospective case series presents two patients treated with titanium cages for limb reconstruction following tumor resection.</div><div>Case 1: A 53-year-old female with a solitary plasmacytoma of the femur experienced a pathological fracture and nonunion after initial treatment. A titanium cage was employed to bridge the resected bone segment, leading to successful callus formation at the six-month follow-up and restored limb function.</div><div>Case 2: A 31-year-old female with a giant cell tumor and hemangioma of the foot underwent en bloc resection followed by reconstruction using a vertebral cage and iliac corticospongious graft. Six months postoperatively, the patient had resumed full weight-bearing with no complications.</div></div><div><h3>Conclusion</h3><div>Titanium cages offer a promising solution for limb reconstruction in patients with tumors, particularly for large bone defects where traditional methods may be inadequate. This case series demonstrates successful outcomes in limb preservation and functional recovery using titanium cages. Their use in the adult population shows potential for broader application in orthopedic oncology, warranting further clinical investigation.</div></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"3 ","pages":"Article 100073"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giovanni De Nobili, Severino Cericola, Vincenzo Casolino, Simone Di Russo, Erika Peca, Rossana Percario, Roberta Dimalio, Gauro D'Urbano, Paolo Panaccio
{"title":"Compartment syndrome following self-injection of hydrocarbon: A case series","authors":"Giovanni De Nobili, Severino Cericola, Vincenzo Casolino, Simone Di Russo, Erika Peca, Rossana Percario, Roberta Dimalio, Gauro D'Urbano, Paolo Panaccio","doi":"10.1016/j.sycrs.2024.100069","DOIUrl":"10.1016/j.sycrs.2024.100069","url":null,"abstract":"<div><h3>Background</h3><p>Hydrocarbon products are generally used by drug addict patients in attempt to emulate drug effects or as a means of self-harm. These substances can be assumed through inhalation or by intravenous or intramuscular injection. When hydrocarbons are injected intramuscularly into the limbs, they can cause the compartment syndrome, necessitating surgical intervention.</p></div><div><h3>Cases series</h3><p>We describe a series of three cases in which compartment syndrome developed following hydrocarbon intramuscular injection of hydrocarbons and was successfully treated with urgent fasciotomy. The cases involve three young men who injected gasoline or diesel fuel in their arms and legs. In each case, urgent fasciotomy was necessary to evacuate the intramuscular collection that was rapidly expanding. The three patients were then discharged from our Surgical Department with no complications and were followed up in outpatient visits.</p></div><div><h3>Conclusion</h3><p>Intramuscular hydrocarbon injection can mainly lead to compartment syndrome and tissue necrosis. In the three cases we have reported, urgent fasciotomy successfully prevented ischemic damage to the limbs and facilitated the drainage of toxic substances, thereby preventing patient’s systemic poisoning and septic lethal consequences.</p></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"3 ","pages":"Article 100069"},"PeriodicalIF":0.0,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950103224000690/pdfft?md5=52d51200834ccef7afe4f6be25574608&pid=1-s2.0-S2950103224000690-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mesut Engin , Abdulkerim Özkan , Ufuk Aydın , Yusuf Ata
{"title":"Surgical aortic root replacement in a patient with midaortic syndrome","authors":"Mesut Engin , Abdulkerim Özkan , Ufuk Aydın , Yusuf Ata","doi":"10.1016/j.sycrs.2024.100064","DOIUrl":"10.1016/j.sycrs.2024.100064","url":null,"abstract":"<div><h3>Background</h3><p>Midaortic syndrome is a rare condition characterized by the narrowing of the abdominal aorta. In this article, we present a 32-year-old male patient who was incidentally diagnosed with midaortic syndrome, and whose severe aortic regurgitation and ascending aortic dilatation were successfully treated with the Bentall procedure.</p></div><div><h3>Case report</h3><p>A 32‐year‐old, male patient was admitted to the emergency department with the complaint of chest pain and dyspnea for 3 months. His medical history was notable for diabetes, hypertension (12 years), and hyperthyroidism. Coronary angiography was normal. Ascending aortic dilatation and interrupted abdominal aorta were revealed with computed tomographic angiography (CTA). The Bentall procedure was performed with median sternotomy.</p></div><div><h3>Conclusion</h3><p>Our case is the first patient in the literature who had Midaortic Syndrome and underwent the Bentall procedure. Additionally, our patient had extremely poor left ventricular functions (LVEF = 20 %). One of the important problems that could occur in this patient was the need for an intra-aortic balloon pump (IABP) for CPB weaning.</p></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"3 ","pages":"Article 100064"},"PeriodicalIF":0.0,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950103224000641/pdfft?md5=bcb88e9577d8c27eacce3c2d4f7f9681&pid=1-s2.0-S2950103224000641-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hesameddin Eghlimi , Amirhassan Rabbani , Hamidreza Movahedi , Tala Tabrizi , Iman Bhia
{"title":"A 24-kilogram retroperitoneal liposarcoma surgical management: A case report","authors":"Hesameddin Eghlimi , Amirhassan Rabbani , Hamidreza Movahedi , Tala Tabrizi , Iman Bhia","doi":"10.1016/j.sycrs.2024.100066","DOIUrl":"10.1016/j.sycrs.2024.100066","url":null,"abstract":"<div><p>Sarcomas are diverse malignant tumors originating from soft tissues (STS) or bones, with STS being more prevalent. Liposarcoma is the most common type of STS, typically arising in the extremities and retroperitoneum. This case report discusses the management of a rare, giant retroperitoneal liposarcoma (RL) in a 47-year-old man presented with significant abdominal enlargement, post-pharyngeal discharge, and urinary dribbling. Medical history included an inguinal hernia and smoking. Diagnosis through imaging (sonography, CT, MRI) and biopsy confirmed a well-differentiated liposarcoma encasing the left kidney and compressing abdominal organs. The tumor measured 53 × 47 x 20 cm and weighed 24 kg. Surgical management included complete tumor excision, left nephrectomy, iliac artery repair, colectomy, and lymph node dissection. The management of RL is challenging due to its size and proximity to vital organs. Complete surgical resection is crucial for recurrence-free survival. Preoperative radiotherapy can aid in achieving negative margins by defining target volumes and reducing irradiation of adjacent tissues. Chemotherapy is reserved for high-grade tumors with metastatic potential. This report highlights the complexities of managing giant RL, underscoring the importance of thorough surgical planning, multidisciplinary collaboration, and assessing potential adjunct therapies to improve patient prognosis.</p></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"3 ","pages":"Article 100066"},"PeriodicalIF":0.0,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950103224000665/pdfft?md5=6db48f451d8804285712baddc3e63bc2&pid=1-s2.0-S2950103224000665-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Nouri , M. Bouziane , Y. Ghaddou , A. Bensaad , A. Fadil , K. Sair , Y. Mahdi , B. El Khannoussi
{"title":"Laparoscopic excision in patient with retroperitoneal schwannoma: A case report","authors":"A. Nouri , M. Bouziane , Y. Ghaddou , A. Bensaad , A. Fadil , K. Sair , Y. Mahdi , B. El Khannoussi","doi":"10.1016/j.sycrs.2024.100065","DOIUrl":"10.1016/j.sycrs.2024.100065","url":null,"abstract":"<div><p>Schwannomas are rare benign tumours that develop on the cranial or spinal nerves. They are often asymptomatic and discovered by chance following pelvic pain. MRI provides a positive diagnosis of the tumour, showing T1 hyposignal, T2 hypersignal, and heterogeneous contrast enhancement. An angioscanner and a uroscanner in the preoperative phase are useful to assess the relationship with neighbouring structures.</p><p>The ideal treatment for schwannomas is complete excision with negative margins, even if it requires the sacrifice of neighbouring organs, given the risk of malignancy and the possibility of recurrence.</p><p>We present a case of a retroperitoneal schwannoma located at the L5-S1 space, diagnosed by MRI following pelvic pain. The treatment involved a laparoscopic transabdominal excision, with a normal postoperative follow-up.</p><p>The aim of this case report is to aid different medical teams in the management of schwannomas and to highlight the advantages of the laparoscopic anterior approach for retroperitoneal tumours compared with laparotomy.</p></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"3 ","pages":"Article 100065"},"PeriodicalIF":0.0,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950103224000653/pdfft?md5=f1a5b1b8bc646f04fbc019abb7c35e71&pid=1-s2.0-S2950103224000653-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rare presentation of pilomatrixoma as a fungating breast mass: Case report and literature review","authors":"Samantha B. Esposito , Claudia B. Perez","doi":"10.1016/j.sycrs.2024.100067","DOIUrl":"10.1016/j.sycrs.2024.100067","url":null,"abstract":"<div><p>Pilomatrixomas are rare tumors arising from the cellular matrix of hair follicles and typically manifest as subcutaneous nodules. This case report highlights a rarer presentation in a 68-year-old female who presented with a protruding, painful left breast mass. After an initial biopsy revealed a benign pilar cyst with keratin material, the tumor exhibited progressive growth, resulting in skin fistulas and calcified material exuding from the skin. Final surgical pathology confirmed a benign pilomatrixoma. This case underscores the importance of timely diagnosis and surgical treatment of this rare tumor to prevent tumor growth, skin erosion, and secondary infection.</p></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"3 ","pages":"Article 100067"},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950103224000677/pdfft?md5=5d95df33bae5a5e72c9b821498a2471b&pid=1-s2.0-S2950103224000677-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142148434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William Markey , Jian Blundell , Cameron Law , Ross Warner
{"title":"Beyond mere appendicitis: A case report on an unforeseen diagnosis of appendiceal schwannoma","authors":"William Markey , Jian Blundell , Cameron Law , Ross Warner","doi":"10.1016/j.sycrs.2024.100068","DOIUrl":"10.1016/j.sycrs.2024.100068","url":null,"abstract":"<div><h3>Introduction</h3><p>Appendiceal schwannomas are a rare diagnosis, with little evidence to guide management and follow-up. There are currently no case reports focusing on follow-up for appendiceal schwannomas after complete surgical resection.</p></div><div><h3>Presentation of case</h3><p>A 64-year-old female presented to the emergency department, febrile, with migratory right iliac fossa pain and focal peritonism, consistent with acute appendicitis. The diagnosis was supported by a computed tomography scan and she underwent a laparoscopic appendicectomy. Histopathology was reported as acute appendicitis associated with a schwannoma at the appendiceal base. The patient underwent a colonoscopy six weeks after her initial surgery with no abnormal findings. Following multidisciplinary team discussion it was decided that no further follow up was required.</p></div><div><h3>Discussion</h3><p>There are only 15 case reports of appendiceal schwannomas in the literature. As a result, the management and follow up in this case was guided from evidence reported in studies of other schwannomas elsewhere in the gastrointestinal tract, standard management of benign appendiceal lesions and MDT discussion. One retrospective single-centre cohort study of histopathology records collected over a 20 year period showed that in 44 patients with GI schwannomas, there was no malignant transformation or recurrence during a mean follow up period of 5.0 ± 4.31 years (Singh et al., 2022). Based on this study there is a very low risk of malignant transformation associated with these lesions.</p></div><div><h3>Conclusion</h3><p>Based on limited published data resection remains the mainstay of management of appendiceal schwannomas. Colonoscopy is recommended to exclude any underlying lesion or synchronous pathology.</p></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"3 ","pages":"Article 100068"},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950103224000689/pdfft?md5=bdb8e8bd4e9f8d8a71e2cfeaf8df1592&pid=1-s2.0-S2950103224000689-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Siddique Khan , Abdal Qureshi , Umar Ali Nazir , Mahad Younas , Lubna Avesi
{"title":"A rare case of hepatic endometriosis and its malignant transformation","authors":"Muhammad Siddique Khan , Abdal Qureshi , Umar Ali Nazir , Mahad Younas , Lubna Avesi","doi":"10.1016/j.sycrs.2024.100060","DOIUrl":"10.1016/j.sycrs.2024.100060","url":null,"abstract":"<div><p>Hepatic endometriosis is a very rare condition that is characterized by the presence of endometrial-like tissue within the hepatic parenchyma. Preoperative diagnosis is often difficult through cross-sectional imaging. Histopathologic evaluation remains the gold standard for diagnosis. Until now only a handful of cases have been reported in medical literature. We report a case of hepatic endometriosis in a 24-year-old, unmarried girl with a history of recurrent hepatic cysts in the right lobe of the liver after two previous surgeries. She underwent a right hepatectomy. The diagnosis was confirmed through histopathology assessment.</p></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"3 ","pages":"Article 100060"},"PeriodicalIF":0.0,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950103224000604/pdfft?md5=aab44bf547ab5f03e35141c3d41240c1&pid=1-s2.0-S2950103224000604-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Halil Ibrahim Bulut , Enes Kanay , Fikret Berkan Anarat , Ayse Nur Toksoz Yildirim , Korhan Ozkan
{"title":"Synchronous multifocal osteosarcoma: Report of 4 cases and literature review","authors":"Halil Ibrahim Bulut , Enes Kanay , Fikret Berkan Anarat , Ayse Nur Toksoz Yildirim , Korhan Ozkan","doi":"10.1016/j.sycrs.2024.100062","DOIUrl":"10.1016/j.sycrs.2024.100062","url":null,"abstract":"<div><h3>Background</h3><p>Multifocal osteosarcoma (MFOS) is rare, accounting for approximately 1.5 % of osteosarcomas, and can be synchronous (lesions within six months) or metachronous (lesions after six months). The etiology and optimal treatment for MFOS remain controversial. This report presents four patients with synchronous MFOS and reviews the literature.</p></div><div><h3>Case presentation</h3><p><em>Case 1:</em> A 24-year-old female with low back pain was found to have multiple lytic bone lesions with increased FDG uptake in the vertebral column and pelvic bones. Biopsy confirmed osteoblastoma-like osteosarcoma. After chemotherapy, she is alive after 5 months.</p><p>Case 2: A 6-year-old girl with right knee pain had a distal femur mass and a calcified inguinal lesion. Biopsies revealed osteoblastic osteosarcoma with metastatic lymph node involvement. Following chemotherapy and surgeries, she experienced recurrence and required further surgery. She is alive after 21 months.</p><p><em>Case 3:</em> A 4-year-old boy with a walking disability had a sclerotic bone lesion in the distal femur and additional lesions in the pelvis and acetabulum. Biopsy confirmed osteoblastic osteosarcoma. Despite treatment, he developed metastases and died 7 months after diagnosis.</p><p><em>Case 4</em>: A 9-year-old girl with right knee swelling had a sclerotic lytic lesion in the distal femur and an acetabular lesion. Biopsies confirmed chondroblastic osteosarcoma. After chemotherapy and surgery, she experienced recurrence and underwent pelvic resection. She died 24 months after diagnosis.</p></div><div><h3>Conclusion</h3><p>Synchronous MFOS is a highly aggressive osteosarcoma variant with a poor prognosis. Aggressive, individualized treatment may improve outcomes, particularly in metachronous cases. Further research is needed to enhance understanding and management of this rare condition.</p></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"3 ","pages":"Article 100062"},"PeriodicalIF":0.0,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950103224000628/pdfft?md5=de41dcb15a6458f9eeeaf760e8b38535&pid=1-s2.0-S2950103224000628-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}