中国现代神经疾病杂志最新文献

{"title":"Risk factors analysis of ischemic cerebrovascular disease combined with restless legs syndrome","authors":"Xuerui Li, Weiliang Zhang, Yu-jing Huang, Yong-bin Song, Heng Xue, Li Yan, Yi-la Ma, Rouziaji Mutipaer, Jiang-tao Xu","doi":"10.3969/cjcnn.v17i10.1676","DOIUrl":"https://doi.org/10.3969/cjcnn.v17i10.1676","url":null,"abstract":"Objective To explore the risk factors for restless legs syndromes (RLS) in patients with ischemic cerebrovascular disease (ICVD).  Methods There were 370 patients with ICVD, 45 cases were combined with RLS (RLS group) and 325 cases were not combined with RLS (non-RLS group). The general clinical data [sex, age, body mass index (BMI), education, nationality, occupation, lifestyle, physical exercise, medical history, history of gestation and age of menopause in female] were recorded, and related chemical examinations [white cell count (WBC), hemoglobin (Hb), serum creatinine (Cr), blood urea nitrogen (BUN), fasting blood glucose, serum lipid, plasma homocysteine (Hcy), serum iron] were performed.  Results Compared with non-RLS group, BMI of patients in RLS group was higher ( t = 2.457, P = 0.014), Hb ( t = 2.819, P = 0.005) and serum iron ( t = 2.168, P = 0.024) were lower. Multivariate forward Logistic regression analysis showed that low Hb ( OR = 1.049, 95%CI: 1.017-1.082; P = 0.002) and serum iron ( OR = 1.121, 95% CI: 1.002-1.254; P = 0.047) were the risk factors for ICVD combined with RLS patients.  Conclusions RLS is common among patients with ICVD, and they have low Hb and serum iron levels. DOI: 10.3969/j.issn.1672-6731.2017.10.008","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"748-753"},"PeriodicalIF":0.0,"publicationDate":"2017-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43763430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress of restless legs syndrome in China: Chinese scholars' reports published abroad","authors":"Chunyan Liu, Yan Ding, Y. Hou, Li Wang, Zhaoyang Huang, S. Zhan, Rong Wang, Yuping Wang","doi":"10.3969/CJCNN.V17I9.1654","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I9.1654","url":null,"abstract":"In recent years, Chinese scholars have made some progress in the field of restless legs syndrome (RLS), including epidemiological investigation of prevalence of RLS in some areas of China, the pathogenesis, comorbidities research, drug therapy and non ? drug therapy of RLS, such as repetitive transcranial magnetic stimulation (rTMS), acupuncture and moxibustion treatment, etc. This has laid a solid foundation for understanding and treating the disease in a better way, and also makes some contributions to RLS research for our country. DOI: 10.3969/j.issn.1672-6731.2017.09.003","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"639-643"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43358053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress of narcolepsy","authors":"F. Xiao, Jun Zhang, F. Han","doi":"10.3969/cjcnn.v17i9.1655","DOIUrl":"https://doi.org/10.3969/cjcnn.v17i9.1655","url":null,"abstract":"The discovery of hypothalamus Hypocretin (Hcrt)/Orexin system and its relationship with narcolepsy is one of the major advances in sleep medicine. Hcrt/Orexin is a significant neurotransmitter in the circadian cycle of arousal. Basic research about Hcrt/Orexin system has been applied in clinical practice and the measurement of Hcrt/Orexin in the cerebrospinal fluid (CSF) is the golden criteria and classification basis for diagnosis of narcolepsy. Breakthrough advance has been made in genetic immunology of hypothalamus Hcrt/Orexin neuronal apoptosis of narcolepsy patients. Medications aimed at Hcrt/Orexin receptors are considered to be a novel target in the treatment of sleep disorders. DOI: 10.3969/j.issn.1672-6731.2017.09.004","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"644-647"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41846981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comorbidity of narcolepsy and schizophrenia: one case report","authors":"Yan Ding, Nam Yin, S. Zhan, Zhaoyang Huang, Ning Li, Y. Hou, Li Wang","doi":"10.3969/cjcnn.v17i9.1660","DOIUrl":"https://doi.org/10.3969/cjcnn.v17i9.1660","url":null,"abstract":"","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"671-673"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42895021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One stage surgical treatment for scoliosis associated with intraspinal abnormalities","authors":"Kai Wang, Hao Wu, F. Jian","doi":"10.3969/cjcnn.v17i9.1662","DOIUrl":"https://doi.org/10.3969/cjcnn.v17i9.1662","url":null,"abstract":"Objective To evaluate the effectiveness and safety of one stage surgical treatment for scoliosis and coexisting intraspinal abnormalities.  Methods The data of 6 patients who underwent one stage surgical treatment for scoliosis and coexisting intraspinal abnormalities from October 2016 to January 2017 were retrospectively analyzed. Treatment for intraspinal abnormalities, posterior correction, osteotomy and internal fixation were performed simultaneously. The clinical and radiologic presentations, operative details, complications and postoperative outcomes were evaluated.  Results The success rate was 100%. The operating time was (470.83 ± 136.20) min and intraoperative bleeding amount was 1350 (625, 2150) ml. Total fusion segments were 11.00 ± 2.76. Both Cobb angle of scoliosis [postoperation (19.60 ± 5.94)° vs. preoperation (59.40 ± 14.31)°, P = 0.007] and kyphosis [postoperation (25.80 ± 10.87)° vs. preoperation (62.40 ± 21.04)°, P = 0.005] were improved after operation. Tethered cords were released and epidermoid cyst, ganglioglioma and lipoma were excised. Syringomyelia was left untreated. No neurological functional defect or worsening was found. Muscle strength of all patients was improved. Muscular tone of 4 patients and difficulty in urination of 5 patients were also improved. The mean hospital stay was (8.83 ± 3.31) d. No severe complications, such as infection, cerebrospinal fluid (CSF) leakage, failed internal fixation, fractured pedicle screws or rods occurred after operation. None of the patients died, or experienced deterioration of neurological function, delayed infection, pseudoarthrosis, or loss correction during the (7.50 ± 1.22) months follow - up. Conclusions The one stage surgical treatment for scoliosis and intraspinal abnormalities seems to be a safe and effective approach. Neurological functional defect can be improved after operation. Osteotomy can improve correction result. DOI: 10.3969/j.issn.1672-6731.2017.09.011","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"680-684"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45575925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress of endovascular therapy for acute ischemic stroke","authors":"Yu-yi Lin, Jing Tan, Xin Lu","doi":"10.3969/cjcnn.v17i9.1664","DOIUrl":"https://doi.org/10.3969/cjcnn.v17i9.1664","url":null,"abstract":"Acute ischemic stroke which has the high mobidity, disability rate and mortality is one of the most serious diseases threatening mankind. Endovascular therapy is difinite. Slection of patient, therapeutic time window and device is closely associated with the prognosis. This paper reviews the issues mentioned above. DOI: 10.3969/j.issn.1672-6731.2017.09.013","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"690-696"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47531340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on insomnia and sleep quality in adolescents and their correlation analysis","authors":"Xian Luo, Wei-xia Li, Bin Zhang","doi":"10.3969/CJCNN.V17I9.1658","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I9.1658","url":null,"abstract":"Objective To investigate the correlation between insomnia and sleep quality in adolescents. Methods According to Insomnia Severity Index (ISI) Chinese Version, 3342 students technician training in school were divided into non insomnia group (N = 2345) and insomnia group (N = 997). Sleep and emotional state were assessed by ISI Chinese Version, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Self?Rating Anxiety Scale (SAS) and Beck Depression Inventory (BDI). The social demographic data were collected simultaneously.  Results The number of insomnia, daytime sleepiness, anxiety and depression in the population was 997 (29.83%), 568 (17.00%), 243 (7.27%) and 1287 (38.51%), respectively. The comparison of social demographic data between 2 groups showed that the proportion of female ( P = 0.000), poor physical condition ( P = 0.000), non?only child ( P = 0.006), high learning pressure ( P = 0.000) and smoking ( P = 0.027) in insomnia group were significantly higher than those in non insomnia group. The total scores of ISI Chinese Version ( P = 0.000), ESS ( P = 0.000), SAS ( P = 0.000) and BDI ( P = 0.000) in insomnia group were significantly higher than those in non insomnia group. Pearson correlation analysis showed that ISI Chinese Version and PSQI scores were positively correlated with ESS score ( r = 0.361, P = 0.000; r = 0.064, P = 0.000), SAS score ( r = 0.326, P = 0.000; r = 0.069, P = 0.000) and BDI score ( r = 0.529, P = 0.000; r = 0.067, P = 0.000), and ISI Chinese Version had higher correlation ( r = 0.300-0.600) with the above scores than PSQI ( r < 0.100). Further partial correlation analysis showed that ISI Chinese Version score was negatively correlated with PSQI score ( r = ? 0.056, P = 0.001). Conclusions Higher proportion of female, worse physical condition, more non?only child, greater learning pressure and higher smoking rate were observed in insomnia group. Daytime sleepiness, anxiety and depression in insomnia group were more serious than those in non insomnia group, but PSQI score can not distinguish the above differences. Compared with PSQI, ISI Chinese Version is more closely related to daytime sleepiness, anxiety and depression, and might be more suitable for assessing insomnia in adolescents. DOI: 10.3969/j.issn.1672-6731.2017.09.007","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"660-664"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46803864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ambulatory video-EEG-EMG monitoring and analysis during cataplexy in narcolepsy","authors":"Bei Huang, Kun Chen, Zongwen Wang, Zhong-xin Zhao, Huijuan Wu","doi":"10.3969/CJCNN.V17I9.1657","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I9.1657","url":null,"abstract":"Objective To comprehensively analyze the clinical and electroneurophysiological characteristics during the process of cataplexy by dynamic video?EEG?EMG monitoring.  Methods Six narcolepsy type 1 patients with typical cataplexy were enrolled and 2 of them were diagnosed as status cataplecticus. All patients underwent polysomnography (PSG) and daytime Multiple Sleep Latency Test (MSLT) to clarify the diagnosis. Cataplexy was triggered by emotional stimulus and recorded under dynamic video-EEG-EMG monitoring. EEG characteristics during cataplexy were further compared and analyzed. Objective To comprehensively analyze the clinical and electroneurophysiological characteristics during the process of cataplexy by dynamic video-EEG-EMG monitoring. Methods Six narcolepsy type 1 patients with typical cataplexy were enrolled and 2 of them were diagnosed as status cataplecticus. All patients underwent polysomnography (PSG) and daytime Multiple Sleep Latency Test (MSLT) to clarify the diagnosis. Cataplexy was triggered by emotional stimulus and recorded under dynamic video-EEG-EMG monitoring. EEG characteristics during cataplexy were further compared and analyzed.  Results Fourteen cataplectic attacks in 6 patients were recorded. According to the clinical and video- EMG characteristics, cataplectic attack was divided into 4 stages, including triggering phase (CA1), resisting phase (CA2), atonic phase (CA3) and recovering phase (CA4). EEG frequency and amplitude varied from one stage to another and hypersynchronous paroxysmal theta (HSPT) was observed in early resisting phase (CA2), which was supposed to be a distinctive EEG characteristic during the onset of cataplexy.  Conclusions Generalized cataplectic  ttack contain 4 stages, which indicate a complicated and dynamic process in clinical and electroneurophysiology. Moreover, it's highly possible that HSPT during resisting phase (CA2) is critical in the mechanism of cataplexy. DOI: 10.3969/j.issn.1672-6731.2017.09.006","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"654-659"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46789359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of sleep - related rhythmic movement disorder in adult with literature review","authors":"Y. Hou, Zhaoyang Huang, Yuping Wang, S. Zhan","doi":"10.3969/CJCNN.V17I9.1659","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I9.1659","url":null,"abstract":"Sleep - related rhythmic movement disorder (RMD) is characterized by repetitive,stereotyped and rhythmic motor behaviors (not tremors) that occur predominantly during drowsiness or sleep and involve large muscle groups. The onset of RMD is typically in early childhood, rarely continue into adolescence and adulthood. This paper retrospectively analyzed the diagnosis and treatment in a case of adult-onset RMD. A 76 -year-old male mainly presented rhythmic forehead banging during sleep. The number of forehead banging ranged from dozens to tens of seconds, pause seconds after the second attack, lasting 1 to 2 h and can not be recalled after waking up. Polysomnography (PSG) showed sleep efficiency decreased, awakening time prolonged, times of wakefulness increased, sleep structure disordered, non-rapid eye movement (NREM) 1 and 2 sleep increased, rapid eye movement (REM) sleep decreased, sleep latency of REM prolonged. Apnea hypopnea index (AHI) was 8.40. Several abnormal behavior attacks were observed, each attack lasting 3 to 18 s, 0.60 to 1.20 Hz, total time lasting 6 min. The diagnosis was RMD, clonazepam 0.50 mg/night and pramipexole 0.0625 mg/night were given and the result of 33 months follow-up showed effective. By literature review, we know the clinical features, diagnosis and treatment of RMD. We also analyze the reasons of misdiagnosis for reducing diagnostic errors and mistreatments. DOI: 10.3969/j.issn.1672-6731.2017.09.008","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"665-670"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44074626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The imaging characteristics and nasal endoscopic repair surgery for delayed postoperative cerebrospinal fluid rhinorrhea in patients with pituitary tumor","authors":"X. Zhai, Jin-ling Zhang, Gang Liu","doi":"10.3969/CJCNN.V17I9.1663","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I9.1663","url":null,"abstract":"Objective To investigate the imaging characteristics and nasal endoscopic repair surgery for delayed postoperative cerebrospinal fluid (CSF) rhinorrhea in patients with pituitary tumor.  Methods From June 2009 to November 2014 there were 23 cases with delayed CSF rhinorrhea in our hospital, which occurred one year to 5 years after the operation for pituitary tumor. Pituitary hormone assay, head MRI, cisternal CT and nasal endoscopic examination were performed in all patients. After definite diagnosis the patients underwent nasal endoscopic repair surgery of CSF rhinorrhea. During the operation, large leakage orifices were packed with muscle, and then patched with xenogenic acellular dermal matrix, while the small ones were directly patched with xenogenic acellular dermal matrix after tumor resection, and the sphenoid sinus was packed with gelatin sponge and iodoform gauze.  Results Patients were hospitalized for 3 to 5 weeks. Among them, 20 patients were successfully recured after one nasal endoscopic repair surgery, 2 underwent the second surgery, and one underwent the third surgery. Patients were followed up for 3 months to 5 years with no CSF rhinorrhea reoccurred.  Conclusions Delayed postoperative CSF rhinorrhea in patients with pituitary tumor were likely due to residual tumor growth and postoperative radiotherapy. Pituitary tumor often occur in sella, thus nasal endoscopic resection and repair surgery is feasible in treatment. The surgery is safe and the success rate is high. DOI: 10.3969/j.issn.1672-6731.2017.09.012","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"685-689"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45001309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}