Risk factors analysis of ischemic cerebrovascular disease combined with restless legs syndrome

Q4 Medicine

中国现代神经疾病杂志 Pub Date : 2017-10-25 DOI:10.3969/cjcnn.v17i10.1676

Xuerui Li, Weiliang Zhang, Yu-jing Huang, Yong-bin Song, Heng Xue, Li Yan, Yi-la Ma, Rouziaji Mutipaer, Jiang-tao Xu

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Abstract

Objective To explore the risk factors for restless legs syndromes (RLS) in patients with ischemic cerebrovascular disease (ICVD). Methods There were 370 patients with ICVD, 45 cases were combined with RLS (RLS group) and 325 cases were not combined with RLS (non-RLS group). The general clinical data [sex, age, body mass index (BMI), education, nationality, occupation, lifestyle, physical exercise, medical history, history of gestation and age of menopause in female] were recorded, and related chemical examinations [white cell count (WBC), hemoglobin (Hb), serum creatinine (Cr), blood urea nitrogen (BUN), fasting blood glucose, serum lipid, plasma homocysteine (Hcy), serum iron] were performed. Results Compared with non-RLS group, BMI of patients in RLS group was higher ( t = 2.457, P = 0.014), Hb ( t = 2.819, P = 0.005) and serum iron ( t = 2.168, P = 0.024) were lower. Multivariate forward Logistic regression analysis showed that low Hb ( OR = 1.049, 95%CI: 1.017-1.082; P = 0.002) and serum iron ( OR = 1.121, 95% CI: 1.002-1.254; P = 0.047) were the risk factors for ICVD combined with RLS patients. Conclusions RLS is common among patients with ICVD, and they have low Hb and serum iron levels. DOI: 10.3969/j.issn.1672-6731.2017.10.008

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缺血性脑血管病合并不宁腿综合征的危险因素分析

目的探讨缺血性脑血管病(ICVD)患者不宁腿综合征(RLS)的危险因素。方法370例ICVD患者，合并RLS组45例，非合并RLS组325例。记录一般临床资料[女性性别、年龄、体重指数(BMI)、文化程度、民族、职业、生活方式、体育锻炼、病史、妊娠史、绝经年龄]，并进行相关化学检查[白细胞计数(WBC)、血红蛋白(Hb)、血清肌酐(Cr)、尿素氮(BUN)、空腹血糖、血脂、血浆同型半胱氨酸(Hcy)、血清铁]。结果与非RLS组比较，RLS组患者BMI增高(t = 2.457, P = 0.014)， Hb降低(t = 2.819, P = 0.005)，血清铁降低(t = 2.168, P = 0.024)。多元正向Logistic回归分析显示，低Hb (OR = 1.049, 95%CI: 1.017-1.082;P = 0.002)和血清铁(OR = 1.121, 95% CI: 1.002-1.254;P = 0.047)为ICVD合并RLS患者的危险因素。结论RLS在ICVD患者中较为常见，且患者Hb和血清铁水平均较低。DOI: 10.3969 / j.issn.1672-6731.2017.10.008

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