Revista Portuguesa de Pneumologia (English Edition)最新文献

{"title":"Atypical pyoderma gangrenosum simulating pectoral abscess managed using negative pressure wound therapy","authors":"J. Soro-García, E.M. García-Fontán, R. Carrasco-Rodríguez, M. Blanco-Ramos, M.A. Cañizares-Carretero","doi":"10.1016/j.rppnen.2017.05.007","DOIUrl":"10.1016/j.rppnen.2017.05.007","url":null,"abstract":"","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2017.05.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35143654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic yield of transbronchial lung cryobiopsy in interstitial lung diseases","authors":"R. Marçôa , R. Linhas , D. Apolinário , S. Campainha , A. Oliveira , C. Nogueira , A. Loureiro , J. Almeida , F. Costa , X. Wen , S. Neves","doi":"10.1016/j.rppnen.2017.07.002","DOIUrl":"10.1016/j.rppnen.2017.07.002","url":null,"abstract":"","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2017.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35421207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of sarcoidosis in the Oporto region (Portugal)","authors":"A.V. Cardoso ,&nbsp;P.C. Mota ,&nbsp;N. Melo ,&nbsp;S. Guimarães ,&nbsp;C. Souto Moura ,&nbsp;J.M. Jesus ,&nbsp;R. Cunha ,&nbsp;A. Morais","doi":"10.1016/j.rppnen.2017.05.004","DOIUrl":"10.1016/j.rppnen.2017.05.004","url":null,"abstract":"<div><h3>Background</h3><p>Sarcoidosis is a systemic granulomatous disease of unknown etiology. Epidemiological studies of different populations are essential because clinical presentation, organ involvement, disease severity, and prognosis vary significantly according to region and population. The aim of this study was to assess epidemiological and clinical characteristics, staging factors, and clinical course in patients with sarcoidosis from a tertiary hospital in Oporto, Portugal.</p></div><div><h3>Methods</h3><p>A retrospective analysis of patients with sarcoidosis and at least 2 years of follow-up evaluated at the Centro Hospitalar de São João between 2000 and 2014.</p></div><div><h3>Results</h3><p>We identified 409 patients with sarcoidosis (females, 58.9%; mean age at diagnosis, 38.9<!--> <!-->±<!--> <!-->13.4 years; smokers, 14.4%]. All the patients were diagnosed according to the ERS/ATS/WASOG consensus statement and 64.1% had evidence of noncaseating epithelioid cell granulomas in biopsy specimens. Bronchoalveolar lavage was performed as part of the diagnostic work-up in 289 patients and 90.2% had lymphocytosis (CD4/CD8 ratio ≥<!--> <!-->3.5 in 60.9% of cases). Exertion dyspnea, cough, and constitutional symptoms were the most common presenting symptoms; 10.1% of patients were asymptomatic, 22.8% had Löfgren syndrome, and 50.5% had extrathoracic involvement. Radiographic stages of disease according to the Scadding criteria were as follows: stage 0 (5.2%), stage I (33.7%), stage II (47.0%), stage III (8.4%), and stage IV (5.7%). Impaired respiratory function was observed in 45.6% patients and was mostly mild. Systemic treatment was administered in 58.6% of cases. Overall, 45.3% of patients experienced disease resolution.</p></div><div><h3>Conclusion</h3><p>The epidemiological and clinical characteristics of this cohort of patients with sarcoidosis from the Oporto region in northern Portugal revealed epidemiological and clinical characteristics that were generally similar to those described in other Western Europe populations and in the US ACCESS study. However, we found a higher proportion of patients who progressed to chronic forms.</p></div>","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2017.05.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35099805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary tuberculosis: Resistance pattern to first line anti-tuberculosis drugs in the Coimbra District, 2000–2011","authors":"R. Eufrásio ,&nbsp;M. Alcobia ,&nbsp;L. Correia","doi":"10.1016/j.rppnen.2016.04.001","DOIUrl":"10.1016/j.rppnen.2016.04.001","url":null,"abstract":"","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2016.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34510943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of bariatric surgery in obstructive sleep apnea in obese patients","authors":"I.M. Guerreiro ,&nbsp;M. Branco ,&nbsp;S. Moreira ,&nbsp;J. Valença","doi":"10.1016/j.rppnen.2016.01.008","DOIUrl":"10.1016/j.rppnen.2016.01.008","url":null,"abstract":"","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2016.01.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41513707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allergic bronchopulmonary aspergillosis treated successfully with omalizumab","authors":"R. Aguiar ,&nbsp;N.P. Fernandes ,&nbsp;A. Lopes ,&nbsp;C. Lopes","doi":"10.1016/j.rppnen.2017.05.006","DOIUrl":"10.1016/j.rppnen.2017.05.006","url":null,"abstract":"","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2017.05.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35166856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The frequency of lung cancer in patients with pulmonary hamartomas: An evaluation of clinical, radiological, and pathological features and follow-up data of 96 patients with pulmonary hamartomas","authors":"G.H. Ekinci ,&nbsp;O. Hacıömeroğlu ,&nbsp;A. Ersev ,&nbsp;L. Alpay ,&nbsp;H. Özgen ,&nbsp;A. Yılmaz","doi":"10.1016/j.rppnen.2017.04.008","DOIUrl":"10.1016/j.rppnen.2017.04.008","url":null,"abstract":"<div><h3>Purpose</h3><p>To investigate the frequency of lung cancer in patients with pulmonary hamartomas and to evaluate clinical, radiological, and pathological characteristics of pulmonary hamartomas.</p></div><div><h3>Basic procedures</h3><p>We reviewed pathology records of pulmonary hamartomas diagnosed between 2003 and 2014. Medical records and the hospital electronic database were also reviewed for each patient to obtain clinical, radiological, and pathological characteristics of pulmonary hamartomas and accompanying malignancies.</p></div><div><h3>Main findings</h3><p>Ninety-six patients with pulmonary hamartomas were identified. There were 26 females (27%) and 70 males (73%), with a mean age of 56.2 years (range 22–87 years). Malignancies were detected in 23 patients (24%), which developed previously in five patients (1 synchronous, 4 metachronous lesions), and concomitantly in 18 patients (with origin from the lung in 17 patients and from the pleura in 1 patient).</p></div><div><h3>Principal conclusions</h3><p>Our results show that patients with pulmonary hamartomas may have coexisting lung malignancies.</p></div>","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2017.04.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35058193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does omalizumab impair glucose homeostasis in a patient with severe persistent asthma and type 2 diabetes mellitus?","authors":"S. Hamada ,&nbsp;A. Kuroe ,&nbsp;M. Tsukino","doi":"10.1016/j.rppnen.2017.05.002","DOIUrl":"10.1016/j.rppnen.2017.05.002","url":null,"abstract":"","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2017.05.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35078676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of exposure to biomass burning on pulmonary inflammatory markers and pulmonary function in individuals with COPD","authors":"D. Ramos ,&nbsp;M. Proença ,&nbsp;M.R. Leite ,&nbsp;A.D. Ferreira ,&nbsp;I.B. Trevisan ,&nbsp;G.F.S. Brígida ,&nbsp;G.Y. Tacao ,&nbsp;E.M.C. Ramos","doi":"10.1016/j.rppnen.2017.04.003","DOIUrl":"10.1016/j.rppnen.2017.04.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Pulmonary rehabilitation (PR) has many benefits for individuals with COPD. However, it is not clear whether PR could prevent the hazards of air pollution exposure. This study aimed to analyze the effects of biomass burning exposure on pulmonary inflammatory markers and pulmonary function in individuals with COPD, participants and non-participants of PR.</p></div><div><h3>Methods</h3><p>35 subjects were divided into three groups: individuals with COPD who received PR (G1, <em>n</em> <!-->=<!--> <!-->15), those who did not (G2, <em>n</em> <!-->=<!--> <!-->10), and a control group composed of healthy individuals without COPD (CG, <em>n</em> <!-->=<!--> <!-->10). Measurements of lung function and concentrations of IL-6, IL-10, and TNF-α in exhaled breath condensate samples were collected. The assessment and concentrations of particulate matter (PM₁₀), nitrogen dioxide (NO₂), ozone (O₃), temperature (T), and relative air humidity (RAH) were recorded in biomass burning and non-burning periods.</p></div><div><h3>Results</h3><p>There was a significant increase in the concentrations of air pollutants in the biomass burning period. In this period, an increase in IL-6 (G1p<!--> <!-->=<!--> <!-->0.041, G2 <em>p</em> <!-->=<!--> <!-->.012), and a reduction in the FEV₁/FVC ratio (G1p<!--> <!-->=<!--> <!-->0.021, G2 <em>p</em> <!-->=<!--> <!-->.007) were observed in individuals with COPD. In G1, the increase in IL-6 concentrations correlated positively with O₃ (<em>r</em> <!-->=<!--> <!-->0.693; <em>p</em> <!-->=<!--> <!-->.006), and negatively with RAH (<em>r</em> <!-->=<!--> <!-->−0.773; <em>p</em> <!-->=<!--> <!-->.003) in the burning period.</p></div><div><h3>Conclusions</h3><p>Individuals with COPD exposed to biomass burning demonstrated increased pulmonary inflammation and a reduction in the FEV₁/FVC ratio, regardless of their engagement in PR.</p></div>","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2017.04.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35099804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are we ready to get in the eye of the storm?","authors":"A. Morais (Editor-in-Chief)","doi":"10.1016/j.rppnen.2017.08.004","DOIUrl":"10.1016/j.rppnen.2017.08.004","url":null,"abstract":"","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2017.08.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35415635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}