Reviews in Gynaecological and Perinatal Practice最新文献_第4页

Editorial Board and Aims and Scope 编辑委员会和目标和范围

Reviews in Gynaecological and Perinatal Practice Pub Date : 2006-06-01 DOI: 10.1016/S1871-2320(06)00010-1

引用次数: 0

Reviews in Gynaecological and Perinatal Practice Pub Date : 2006-06-01 DOI: 10.1016/j.rigp.2005.09.008

Neil Johnson

{"title":"Management of dysmenorrhoea","authors":"Neil Johnson","doi":"10.1016/j.rigp.2005.09.008","DOIUrl":"10.1016/j.rigp.2005.09.008","url":null,"abstract":"<div>Accurate diagnosis is important to ensure optimal management of dysmenorrhoea—for women whose dysmenorrhoea does not respond to first line treatments, diagnostic laparoscopy is often useful. Randomised trials have confirmed the effectiveness of a wide and varied array of treatments: conservative approaches including aerobic exercise, topical heat, relaxation therapy, high frequency transcutaneous electrical nerve stimulation (TENS) and timely diagnostic ultrasound; drug treatments including paracetamol and non-steroidal anti-inflammatory drugs, hormonal drug treatments for endometriosis, progestogen drug treatment for unexplained chronic pelvic pain; alternative and newer drug treatments including Vitamin B1, Vitamin E, magnesium, fish oil, toki-shakuyaku-san; surgical treatments including laparoscopic excision and laparoscopic ablation for endometriosis, laparoscopic ovarian cystectomy for endometriomas, the levonorgestrel intrauterine system as a post-operative adjunct for endometriosis, and laparoscopic uterine nerve ablation for primary dysmenorrhoea. The future research agenda has been defined by gaps in randomised trial evidence where data are insufficient or conflicting.</div>","PeriodicalId":101088,"journal":{"name":"Reviews in Gynaecological and Perinatal Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rigp.2005.09.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76271922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Prophylactic oophorectomy for ovarian cancer 预防性卵巢切除术治疗卵巢癌

Reviews in Gynaecological and Perinatal Practice Pub Date : 2006-06-01 DOI: 10.1016/j.rigp.2005.09.006

Christina S. Chu, George Coukos

引用次数: 2

Placental cell turnover in health and disease 胎盘细胞在健康和疾病中的更新

Reviews in Gynaecological and Perinatal Practice Pub Date : 2006-06-01 DOI: 10.1016/j.rigapp.2005.12.003

Alexander Heazell , Lynda Harris , Karen Forbes , Ian Crocker

{"title":"Placental cell turnover in health and disease","authors":"Alexander Heazell , Lynda Harris , Karen Forbes , Ian Crocker","doi":"10.1016/j.rigapp.2005.12.003","DOIUrl":"10.1016/j.rigapp.2005.12.003","url":null,"abstract":"<div>Pre-eclampsia (PE) and intra-uterine growth restriction (IUGR) cause significant maternal and perinatal morbidity and mortality. Placental dysfunction is central to the development of both conditions. Although the pathophysiology of these conditions is unknown, there is common placental pathology with an increase in apoptotic cell death seen within the trophoblast. In addition, in pre-eclampsia, apoptotic fragments of syncytiotrophoblast have been detected in the maternal circulation. Both hypoxia and reactive oxygen species have been proposed as potential mediators of the insults to the placenta in pre-eclampsia and IUGR resulting in apoptosis. Cell proliferation and apoptosis are tightly regulated by oncoproteins. The increased apoptosis observed within trophoblast is associated with an alteration in oncoprotein expression within placental tissue. Further investigation of these oncoproteins capable of detecting or responding to cell damage may improve understanding of the pathophysiology of pre-eclampsia and IUGR.</div>","PeriodicalId":101088,"journal":{"name":"Reviews in Gynaecological and Perinatal Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rigapp.2005.12.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80491214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

The role of the placenta in the developmental origins of health and disease—Implications for practice 胎盘在健康和疾病的发育起源中的作用-对实践的影响

Reviews in Gynaecological and Perinatal Practice Pub Date : 2006-06-01 DOI: 10.1016/j.rigapp.2005.12.001

Rohan M. Lewis , Kirsten R. Poore , Keith M. Godfrey

{"title":"The role of the placenta in the developmental origins of health and disease—Implications for practice","authors":"Rohan M. Lewis , Kirsten R. Poore , Keith M. Godfrey","doi":"10.1016/j.rigapp.2005.12.001","DOIUrl":"10.1016/j.rigapp.2005.12.001","url":null,"abstract":"<div>The placenta is actively involved in transporting nutrients to the fetus, it has both direct and indirect effects on fetal cardiovascular function and has endocrine influences on the mother and fetus. As such, a properly functioning placenta is crucial for normal fetal development and plays a central role in mediating effects of the maternal environment on the fetus. An altered external environment or abnormal placental function can induce developmental changes in the fetus and may have important consequences for the risk of cardiovascular and metabolic disease in adult life.The developmental origins hypothesis proposes that the early environment, from the periconceptional period until early childhood, can predispose an individual to adult cardiovascular and metabolic disease. This hypothesis is supported by epidemiological studies and by work in animals. These effects do not just act in low birth weight babies but have been shown to occur within the normal range of birth weight. It is thought that fetal adaptations to an impaired intra-uterine environment may enhance survival in early life but have deleterious effects in later life.Experimental studies suggest that maternal diet and body composition can alter placental structure and function, and we have recently demonstrated associations between a woman's nutritional state before pregnancy and placental function at term. To elucidate these relationships, further work is needed to define markers of placental function and to characterize their relation to rates of fetal growth.Understanding how the placenta mediates maternal influences will be crucial in determining the mechanisms underlying developmental programming. This will allow the design of targeted public health interventions, both before and during pregnancy, to enhance placental function and thereby improve the health of the offspring throughout life.</div>","PeriodicalId":101088,"journal":{"name":"Reviews in Gynaecological and Perinatal Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rigapp.2005.12.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79646942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16