D. Berardi, R. Keller, Michele Magnani, S. Palazzi, I. Tarricone
{"title":"Assessment protocol of autistic and psychotic dimensions for community mental health centers engaging with child and adolescent psychiatry [Protocollo di assessment delle dimensioni autistica e psicotica per i Centri di Salute Mentale che si interfacciano con la Neuropsichiatria Infantile]","authors":"D. Berardi, R. Keller, Michele Magnani, S. Palazzi, I. Tarricone","doi":"10.1016/J.QUIP.2012.01.007","DOIUrl":"https://doi.org/10.1016/J.QUIP.2012.01.007","url":null,"abstract":"","PeriodicalId":101052,"journal":{"name":"Quaderni Italiani di Psichiatria","volume":"7 1","pages":"7-9"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75178360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucia Godini , Giovanni Castellini , Carolina Lo Sauro , Valdo Ricca , Carlo Faravelli
{"title":"La night eating syndrome","authors":"Lucia Godini , Giovanni Castellini , Carolina Lo Sauro , Valdo Ricca , Carlo Faravelli","doi":"10.1016/j.quip.2011.06.005","DOIUrl":"10.1016/j.quip.2011.06.005","url":null,"abstract":"<div><h3>Introduction</h3><p>The night eating syndrome (NES) is a disorder that has been the object of interest in the scientific community only in recent years. For this reason, there are no universally accepted diagnostic criteria for this syndrome, and data in the literature on NES are often discordant. We conducted a critical review of the literature, which focused on the epidemiologic, psychopathological, and clinical features of NES, in order to provide a systematic analysis of the most relevant data in the field.</p></div><div><h3>Materials and methods</h3><p>We carried out a search of the PubMed and MedLine electronic archives and scientific books for studies and reviews regarding NES published since 1990.</p></div><div><h3>Results and discussion</h3><p>The reported prevalence of NES varies widely in both community and clinical samples. The core symptoms of NES are evening hyperphagia, morning anorexia, nocturnal eating, and insomnia. The syndrome is also frequently associated with important medical and psychiatric comorbidities. Thus far, there is a dearth of reliable data regarding therapeutic strategies for NES, although the results of some studies suggest that pharmacological (sertraline and topiramate) or psychotherapeutic (cognitive behavior therapy) interventions might be useful.</p></div>","PeriodicalId":101052,"journal":{"name":"Quaderni Italiani di Psichiatria","volume":"30 3","pages":"Pages 115-128"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.quip.2011.06.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79987986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"La depressione maggiore resistente: update delle strategie di trattamento farmacologico","authors":"Cesario Bellantuono","doi":"10.1016/j.quip.2011.08.001","DOIUrl":"10.1016/j.quip.2011.08.001","url":null,"abstract":"<div><h3>Introduction</h3><p>A significant number of depressed patients has a treatment-resistant depression (TRD). Many clinical trials, as well as the STAR-D study, have shown that in major depression the initial response to treatment with an effective antidepressant drug is often unsatisfactory.</p></div><div><h3>Material and methods</h3><p>The aim of this review is to provide an updated overview of the psychopharmacological options available for the management of TRD.</p></div><div><h3>Results</h3><p>A number of therapeutic strategies such as switch, combination and augmentation has been assessed in TRD. The most widely used involves a combination between a second generation antipsychotic (SGA) and a serotoninergic antidepressant (SSRI-SNRI).</p></div><div><h3>Conclusions</h3><p>SGA augmentation is a safe and effective option for the treatment of resistant depression. Thus far quetiapine is the only drug that has been approved for this purpose in Italy.</p></div>","PeriodicalId":101052,"journal":{"name":"Quaderni Italiani di Psichiatria","volume":"30 3","pages":"Pages 106-114"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.quip.2011.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76409452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"La compromissione del funzionamento sociale precedente l’esordio psicotico","authors":"Elisa Mori, Domenico Berardi","doi":"10.1016/j.quip.2011.06.006","DOIUrl":"10.1016/j.quip.2011.06.006","url":null,"abstract":"<div><h3>Introduction</h3><p>Treatment of schizophrenia is frequently associated with poor social outcomes, even when it improves positive symptoms. This observation suggests that the social deficits might be an independent psychopathological area that was present before the onset of psychosis. We conducted a short review of the literature to analyze published data on the premorbid social functioning of patients with psychosis.</p></div><div><h3>Materials and methods</h3><p>We conducted a short review of published reports (English only) of case-control trials that examined premorbid social functioning in patients with psychosis. The literature search was conducted electronically and involved the PubMed, EmBase, and PsychINFO databases (1988-2009). Search terms included [social adjustment] or [premorbid social adjustment] or [social development] and [schizophrenia] or [early psychosis], alone or in combination. The references cited in each single article were manually searched to complete the review.</p></div><div><h3>Results</h3><p>The literature search identified 23 studies that documented impairments in the premorbid social functioning of patients with psychosis. These deficits involved different areas of social performance, but they did not appear to be distinctive of schizophrenia. In fact, some studies with controls suffering from other psychiatric diseases failed to find significant differences between the premorbid social functioning of these patients and those with schizophrenia.</p></div><div><h3>Conclusions</h3><p>Further research should analyze premorbid social functioning in patients with schizophrenia to provide a more detailed description of its characteristic aspects.</p></div>","PeriodicalId":101052,"journal":{"name":"Quaderni Italiani di Psichiatria","volume":"30 3","pages":"Pages 97-105"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.quip.2011.06.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74078605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevenire si può, anzi si deve. Il caso della depressione in gravidanza e nel post-partum","authors":"Claudio Mencacci","doi":"10.1016/j.quip.2011.10.001","DOIUrl":"10.1016/j.quip.2011.10.001","url":null,"abstract":"","PeriodicalId":101052,"journal":{"name":"Quaderni Italiani di Psichiatria","volume":"30 3","pages":"Pages 95-96"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.quip.2011.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80091156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gli antipsicotici di seconda generazione nella prevenzione delle recidive in corso di disturbo bipolare: focus su aripiprazolo e quetiapina","authors":"Angelo Cerù","doi":"10.1016/j.quip.2011.09.001","DOIUrl":"10.1016/j.quip.2011.09.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Mood stabilization is an important goal in the treatment of bipolar disorder. In addition to well-established mood stabilizers (lithium, certain anticonvulsants), atypical antipsychotic drugs, including aripiprazole and quetiapine, have also been assessed for this purpose.</p></div><div><h3>Materials and methods</h3><p>This article reviews two studies on atypical antipsychotic monotherapy for mood stabilization: one that examined aripiprazole, the other quetiapine. Both studies had designs similar to those used to obtain regulatory approval of these drugs for long-term treatment of bipolar disorder.</p></div><div><h3>Results</h3><p>Aripiprazole prevented manic relapses but not the depressive ones, whereas quetiapine was able to prevent both types of recurrence. The safety profiles of the two drugs were compatible with previously reported data.</p></div><div><h3>Discussion</h3><p>Compared with aripiprazole, quetiapine seems to be more effective for the prevention of acute recurrences in patients with bipolar disorder.</p></div>","PeriodicalId":101052,"journal":{"name":"Quaderni Italiani di Psichiatria","volume":"30 3","pages":"Pages 129-136"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.quip.2011.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74326393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"La risposta subottimale al trattamento antidepressivo: definizione e implicazioni cliniche","authors":"Bernardo Carpiniello","doi":"10.1016/j.quip.2011.06.001","DOIUrl":"10.1016/j.quip.2011.06.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Insufficient responses to antidepressant drugs can be an important problem, with negative clinical and psychosocial consequences.</p></div><div><h3>Materials and methods</h3><p>On the basis of an extensive analysis of the existing literature, the authors provide a possible operational definition of suboptimal treatment response and review the available data on the frequency of this phenomenon and its implications.</p></div><div><h3>Results</h3><p>A suboptimal response to antidepressant therapy is defined as a partial response or one that includes residual sub-threshold symptoms. These responses are associated with an increased risk for recurrence/relapses, shorter times to recurrence/relapse, higher risks of disease chronicity and suicidal tendencies, reduced functioning, and increases in the costs of care. Suboptimal responses are observed in approximately 70% of all patients after the first cycle of treatment, but with repeated attempts at treatment, this rate drops to approximately one third of cases.</p></div><div><h3>Conclusions</h3><p>Given their frequency and negative consequences, suboptimal responses to antidepressant therapy can be a challenge for clinicians, and complex strategies (e.g., augmentation, add-on, or switching) are often needed to overcome the limitations of the treatment.</p></div>","PeriodicalId":101052,"journal":{"name":"Quaderni Italiani di Psichiatria","volume":"30 2","pages":"Pages 58-64"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.quip.2011.06.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83938123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}