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Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics最新文献

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Thyroid function tests and their alterations by drugs 甲状腺功能测试及其药物改变
Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics Pub Date : 1976-01-01 DOI: 10.1016/S0362-5486(76)80026-X
Inder J. Chopra, David H. Solomon
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引用次数: 5
Clinical use of thyrotropin-releasing hormone 促甲状腺激素释放激素的临床应用
Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics Pub Date : 1976-01-01 DOI: 10.1016/S0362-5486(76)80025-8
Clark T. Sawin, Jerome M. Hershman
{"title":"Clinical use of thyrotropin-releasing hormone","authors":"Clark T. Sawin, Jerome M. Hershman","doi":"10.1016/S0362-5486(76)80025-8","DOIUrl":"10.1016/S0362-5486(76)80025-8","url":null,"abstract":"","PeriodicalId":101017,"journal":{"name":"Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics","volume":"1 3","pages":"Pages 351-366"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0362-5486(76)80025-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82215063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Acute and subacute thyroiditis 急性和亚急性甲状腺炎
Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics Pub Date : 1976-01-01 DOI: 10.1016/S0362-5486(76)80013-1
R. Volpe
{"title":"Acute and subacute thyroiditis","authors":"R. Volpe","doi":"10.1016/S0362-5486(76)80013-1","DOIUrl":"https://doi.org/10.1016/S0362-5486(76)80013-1","url":null,"abstract":"","PeriodicalId":101017,"journal":{"name":"Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics","volume":"116 1","pages":"171-181"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75999337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Treatment of hyperthyroidism in children and adolescents 儿童和青少年甲状腺机能亢进的治疗
Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics Pub Date : 1976-01-01 DOI: 10.1016/S0362-5486(76)80010-6
H. Verdain Barnes
{"title":"Treatment of hyperthyroidism in children and adolescents","authors":"H. Verdain Barnes","doi":"10.1016/S0362-5486(76)80010-6","DOIUrl":"https://doi.org/10.1016/S0362-5486(76)80010-6","url":null,"abstract":"<div><p>The therapy of thyrotoxicosis in children and adolescents requires careful selection of a primary mode of therapy and secondary therapy if the hypermetabolic manifestations compromise the patient's function at home or in school. The three principle modes of primary therapy, thioamide blockade, subtotal thyroidectomy and radioiodine, are critically reviewed as to advantages, disadvantages, and results. Secondary symptomatic therapy is discussed with an emphasis on the usefulness of beta adrenergic blockade. The application of each potential mode of therapy is discussed. The etiology, natural history, and therapy of neonatal thyrotoxicosis is reviewed. The author concludes that for the majority of patients in this age group with toxic diffuse goiter, definitive thioamide therapy carries the least potential for major complications. An effective approach for utilizing methimazole is outlined.</p></div>","PeriodicalId":101017,"journal":{"name":"Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics","volume":"1 1","pages":"Pages 129-147"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0362-5486(76)80010-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91684317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Treatment of hyperthyroidism in children and adolescents 儿童和青少年甲状腺机能亢进的治疗
Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics Pub Date : 1976-01-01 DOI: 10.1016/S0362-5486(76)80010-6
H. Barnes
{"title":"Treatment of hyperthyroidism in children and adolescents","authors":"H. Barnes","doi":"10.1016/S0362-5486(76)80010-6","DOIUrl":"https://doi.org/10.1016/S0362-5486(76)80010-6","url":null,"abstract":"","PeriodicalId":101017,"journal":{"name":"Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics","volume":"57 1","pages":"129-147"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80616444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Iodine-induced goiter; effects of high iodine intake on thyroid function Iodine-induced甲状腺肿;高碘摄入对甲状腺功能的影响
Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics Pub Date : 1976-01-01 DOI: 10.1016/S0362-5486(76)80005-2
Shigenobu Nagataki
{"title":"Iodine-induced goiter; effects of high iodine intake on thyroid function","authors":"Shigenobu Nagataki","doi":"10.1016/S0362-5486(76)80005-2","DOIUrl":"10.1016/S0362-5486(76)80005-2","url":null,"abstract":"","PeriodicalId":101017,"journal":{"name":"Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics","volume":"1 1","pages":"Pages 45-56"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0362-5486(76)80005-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90072470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Myxedema coma
Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics Pub Date : 1976-01-01 DOI: 10.1016/S0362-5486(76)80012-X
John T. Nicoloff
{"title":"Myxedema coma","authors":"John T. Nicoloff","doi":"10.1016/S0362-5486(76)80012-X","DOIUrl":"https://doi.org/10.1016/S0362-5486(76)80012-X","url":null,"abstract":"","PeriodicalId":101017,"journal":{"name":"Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics","volume":"1 1","pages":"Pages 161-169"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0362-5486(76)80012-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91684318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative clinical pharmacology of thyroid hormones 甲状腺激素的比较临床药理学
Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics Pub Date : 1976-01-01 DOI: 10.1016/S0362-5486(76)80024-6
Herbert A. Selenkow , Leslie I. Rose
{"title":"Comparative clinical pharmacology of thyroid hormones","authors":"Herbert A. Selenkow ,&nbsp;Leslie I. Rose","doi":"10.1016/S0362-5486(76)80024-6","DOIUrl":"10.1016/S0362-5486(76)80024-6","url":null,"abstract":"","PeriodicalId":101017,"journal":{"name":"Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics","volume":"1 3","pages":"Pages 331-349"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0362-5486(76)80024-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84668254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Hyperthyroidism. Causes, etiology of Graves’ disease, clinical features, general aspects of treatment 甲状腺机能亢进。格雷夫斯病的病因、病因学、临床特点、治疗的一般方面
Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics Pub Date : 1976-01-01 DOI: 10.1016/S0362-5486(76)80027-1
David Lewis Geffner, Jerome M. Hershman
{"title":"Hyperthyroidism. Causes, etiology of Graves’ disease, clinical features, general aspects of treatment","authors":"David Lewis Geffner,&nbsp;Jerome M. Hershman","doi":"10.1016/S0362-5486(76)80027-1","DOIUrl":"10.1016/S0362-5486(76)80027-1","url":null,"abstract":"<div><p>The etiology of Graves’ disease remains unknown. The leading current theory considers it to be an hereditary autoimmune disorder of both humoral and cell-mediated immunity with production of abnormal thyroid stimulators. Uncommon causes of hyperthyroidism include autonomous thyroid nodules, administration of iodine to patients with nodular goiter, subacute thyroiditis, trophoblastic tumors producing molar thyrotropin, large differentiated thyroid carcinomas, struma ovarii, pituitary tumors producing thyrotropin, and taking excessive amounts of thyroid medication.</p><p>The clinical features of hyperthyroidism are described. Subtotal thyroidectomy is effective treatment, but has the disadvantage of significant complications which include hypothyroidism, rare mortality, hypoparathyroidism, paralysis of vocal cords and altered voice, recurrence of hyperthyroidism, rare thyroid crisis and morbidity from the wound.</p></div>","PeriodicalId":101017,"journal":{"name":"Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics","volume":"1 3","pages":"Pages 401-422"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0362-5486(76)80027-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79990283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The treatment of thyrotoxicosis by radioiodine 放射性碘治疗甲状腺毒症
Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics Pub Date : 1976-01-01 DOI: 10.1016/S0362-5486(76)80008-8
G. M. Wilson
{"title":"The treatment of thyrotoxicosis by radioiodine","authors":"G. M. Wilson","doi":"10.1016/S0362-5486(76)80008-8","DOIUrl":"https://doi.org/10.1016/S0362-5486(76)80008-8","url":null,"abstract":"","PeriodicalId":101017,"journal":{"name":"Pharmacology & Therapeutics. Part C: Clinical Pharmacology and Therapeutics","volume":"1 1","pages":"101-118"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76571849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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