PathogenesisPub Date : 2015-01-01DOI: 10.1016/j.pathog.2015.05.003
Paul D. Barrett , Hannah E. Barrett
{"title":"An audit into use of minimum dataset reporting of skin cancers in the North of England Cancer Network","authors":"Paul D. Barrett , Hannah E. Barrett","doi":"10.1016/j.pathog.2015.05.003","DOIUrl":"https://doi.org/10.1016/j.pathog.2015.05.003","url":null,"abstract":"","PeriodicalId":101002,"journal":{"name":"Pathogenesis","volume":"2 1","pages":"5-8"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.pathog.2015.05.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72256747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathogenesisPub Date : 2015-01-01DOI: 10.1016/j.pathog.2015.05.004
Jessica S. Black , Manuel Salto-Tellez , Ken I. Mills , Mark A. Catherwood
{"title":"The impact of next generation sequencing technologies on haematological research – A review","authors":"Jessica S. Black , Manuel Salto-Tellez , Ken I. Mills , Mark A. Catherwood","doi":"10.1016/j.pathog.2015.05.004","DOIUrl":"https://doi.org/10.1016/j.pathog.2015.05.004","url":null,"abstract":"","PeriodicalId":101002,"journal":{"name":"Pathogenesis","volume":"2 1","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.pathog.2015.05.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72256748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathogenesisPub Date : 2015-01-01DOI: 10.1016/j.pathog.2015.05.001
Ian A. Cree
{"title":"Liquid biopsy for cancer patients: Principles and practice","authors":"Ian A. Cree","doi":"10.1016/j.pathog.2015.05.001","DOIUrl":"10.1016/j.pathog.2015.05.001","url":null,"abstract":"<div><p>Liquid biopsy has the potential to provide information about cancers without invasive biopsy, using circulating biomarkers. These include proteins, RNA and DNA. They can be used in detection, diagnosis, monitoring and detection of recurrence. While protein-based tumour markers have been used in routine pathology for many years, the ability to detect mutations in circulating DNA is relatively new, and poised to enter clinical practice. A number of issues remain, and it is important that such markers are fully validated before they enter clinical practice. Evidence of clinical utility and cost effectiveness are major hurdles, but it is likely that the use of liquid biopsy in defined settings could benefit cancer patients substantially.</p></div>","PeriodicalId":101002,"journal":{"name":"Pathogenesis","volume":"2 1","pages":"Pages 1-4"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.pathog.2015.05.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83367721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathogenesisPub Date : 2014-01-01DOI: 10.1016/j.pathog.2014.07.001
I.S. Farrell , K. Brelsford , W. Salman , C.J. Smart
{"title":"Low-grade fibromyxoid sarcoma of the transverse colon: A case report","authors":"I.S. Farrell , K. Brelsford , W. Salman , C.J. Smart","doi":"10.1016/j.pathog.2014.07.001","DOIUrl":"10.1016/j.pathog.2014.07.001","url":null,"abstract":"<div><p>A 52 year old lady presented with non-specific abdominal symptoms and menorrhagia. Ultrasound scan revealed an incidental finding of a large soft tissue mass. This was further characterised with a CT scan which revealed a 15 cm × 10 cm × 7 cm multilobulated mass. This was removed via a subtotal colectomy. Initial histology was reported as a most likely diagnosis of gastro-intestinal stromal tumour (GIST) but further characterisation revealed this to be a low-grade fibromyxoid sarcoma.</p><p>This is only the second reported case of low-grade fibromyxoid sarcoma of the colon and would potentially have been missed had not the sample been sent for second opinion at a regional specialist centre.</p></div>","PeriodicalId":101002,"journal":{"name":"Pathogenesis","volume":"1 1","pages":"Pages 1-3"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.pathog.2014.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80528526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}