Journal of Pediatric Surgery Open最新文献

{"title":"Editorial Board Page","authors":"","doi":"10.1016/S2949-7116(24)00049-2","DOIUrl":"10.1016/S2949-7116(24)00049-2","url":null,"abstract":"","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"7 ","pages":"Article 100164"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000492/pdfft?md5=23bc44533f72d7ff8393a6e7a7e13ac2&pid=1-s2.0-S2949711624000492-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pilot study: Significance of I-FABP2 in the diagnosis of acute abdominal episodes in children","authors":"Szymon Gryboś ,&nbsp;Viera Karaffová ,&nbsp;Milan Kuchta ,&nbsp;Peter Krcho","doi":"10.1016/j.yjpso.2024.100146","DOIUrl":"10.1016/j.yjpso.2024.100146","url":null,"abstract":"<div><h3>Background</h3><p>Pediatric abdominal conditions, including necrotizing gastrointestinal diseases, pose significant diagnostic challenges due to clinic symptoms and limited diagnostic tools. Intestinal fatty acid binding protein 2 (I-FABP2) has emerged as a potential biomarker for intestinal damage, but its efficacy in diagnosing pediatric intestinal necrosis remains under explored.</p></div><div><h3>Methods</h3><p>A prospective study was conducted on 55 pediatric patients presenting with abdominal pain and suspected intestinal necrosis or intestinal perforation. Clinical, laboratory, and radiological data were collected, and intraoperative assessment of bowel necrosis was performed. Gene expression of I-FABP2 in peripheral blood was measured using Real-Time RT-PCR, and correlations with surgery and laboratory parameters were analyzed.</p></div><div><h3>Results</h3><p>Intraoperative assessment revealed a moderate sensitivity (61.1%) and specificity (73.7%) of I-FABP2 in identifying bowel necrosis. Positive predictive value (PPV) was high (81.5%), indicating a high likelihood of the condition when I-FABP2 is positive. However, the negative predictive value (NPV) was limited (50%), suggesting challenges in confidently excluding necrosis based on negative I-FABP2 results. Correlations were observed between I-FABP2 expression and elevated levels of C-reactive protein (CRP), interleukin-6 (IL-6), and white blood cell count (WBC), indicating its association with inflammatory processes.</p></div><div><h3>Conclusions</h3><p>While I-FABP2 shows promise as a biomarker for pediatric intestinal necrosis, its diagnostic utility may be enhanced when considered alongside other clinical parameters. Further research and validation studies are warranted to refine its clinical application and improve diagnostic accuracy in pediatric gastrointestinal conditions.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"8 ","pages":"Article 100146"},"PeriodicalIF":0.0,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000315/pdfft?md5=21a1c6f80de62c71255bfa1aade16414&pid=1-s2.0-S2949711624000315-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142058488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistochemistry study of PHOX2B expression in Hirschsprung's disease allied disorders","authors":"Huan Wang,&nbsp;Xiulei Sun,&nbsp;Likun Yu,&nbsp;Yiyuan Xu","doi":"10.1016/j.yjpso.2024.100148","DOIUrl":"10.1016/j.yjpso.2024.100148","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to investigate the significance of PHOX2B expression in Hirschsprung's disease allied disorders (HAD).</p></div><div><h3>Methods</h3><p>Eight specimens of HAD were surgically resected and collected at Beijing Children's Hospital Affiliated to Capital Medical University Heilongjiang Hospital in recent years. Additionally, three specimens from patients with immature ganglion development in the intestinal wall and six control specimens from normal colons were also collected. PHOX2B, S-100, and CR antibodies were used for immunohistochemical staining to observe their expression at the mucosal, submucosal, and intrinsic muscular layer ganglia.</p></div><div><h3>Results</h3><p>In the control group,the nuclei of the submucosal and myenteric ganglion cells showed strong or weak PHOX2B staining pattern,the mature ganglion cells showed weak PHOX2B staining,and the immature ganglion cells showed strong staining;S-100 only stained nerve fibers but not ganglion cells; CR stained nerve fibers in the mucosal layer and submucosal layer and also stained ganglion cells. These three antibodies showed different expression patterns in poorly developed enteric ganglia and immature enteric ganglion cells.</p></div><div><h3>Conclusion</h3><p>PHOX2B is only expressed in the nucleus of ganglion cells, has discriminatory significance in identifying mature and immature ganglion cells, and is an essential marker for diagnosing HAD.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"7 ","pages":"Article 100148"},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000339/pdfft?md5=10649e1203efdabd43cc634633648df5&pid=1-s2.0-S2949711624000339-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141401420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-reduction observation and recurrence of pediatric intussusception in New Zealand: A national multicenter retrospective study","authors":"Brodie M. Elliott ,&nbsp;Jonathan M. Wells ,&nbsp;Shona Naera ,&nbsp;Andrew Weston ,&nbsp;Jacqueline Copland ,&nbsp;Shirin Gosavi ,&nbsp;Kristine Jung ,&nbsp;Udaya Samarakkody ,&nbsp;Georges K. Tinawi ,&nbsp;Samuel Haysom ,&nbsp;Rieke L. Meister ,&nbsp;Christopher I. Cassady ,&nbsp;Stephen Evans","doi":"10.1016/j.yjpso.2024.100155","DOIUrl":"https://doi.org/10.1016/j.yjpso.2024.100155","url":null,"abstract":"<div><h3>Background</h3><p>Intussusception is the most common cause of preschool intestinal obstruction. International data suggest that following uncomplicated enema reduction, 4-hour observation with prompt return to oral diet is safe. We aimed to investigate the rate and timing of intussusception recurrence across Aotearoa New Zealand, compared to the cost of routine post-reduction observation.</p></div><div><h3>Methods</h3><p>We performed a national 15-year retrospective, multicenter cohort study of all children treated for intussusception between 01 Jan 2007 and 01 Jan 2022 across AoNZ. A robust clinical dataset was collected using a REDCap proforma. We also investigated the financial and time costs of current in-hospital observation practices.</p></div><div><h3>Results</h3><p>During this period, primary enema reduction without general anesthetic was successful in 339 cases, requiring a median of 2 attempts (1–8). The median age was 0.8 years; 70.8% were male, and 17.1% were Māori. The median length of hospital stay was 25.9 h, primarily comprised of post-reduction observation (21.6 h). Intussusception recurrence within 30 days occurred in 29 children (8.5%) at a median time of 24.7 h post-reduction. Of the 19 cases recurring before discharge, 12 (3.5%) recurred between 4 and 24 h. The median observation period for those with successful primary enema reduction was 21.6 h; if reduced to 4 h, savings of NZD 883,632 (USD 529,825) and 7342 ward hours were possible.</p></div><div><h3>Conclusions</h3><p>Nationally, the intussusception recurrence rate after uncomplicated enema reduction was 8.5%, but only 3.5% occurred between the 4–24 hour period post-reduction. Expediting discharge by avoiding routine overnight observation appears safe and economically viable.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"7 ","pages":"Article 100155"},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000406/pdfft?md5=c60ac96156584f54e099bc3c49f4db4d&pid=1-s2.0-S2949711624000406-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141323365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vacuum assisted closure therapy in children with complicated abdominal wounds, with or without viscero-cutaneous fistulae","authors":"","doi":"10.1016/j.yjpso.2024.100153","DOIUrl":"10.1016/j.yjpso.2024.100153","url":null,"abstract":"<div><h3>Background</h3><p>Management of complicated abdominal wounds is challenging in children. Vacuum-assisted closure proved to be beneficial. We aimed to report the outcome of VAC over 5 years’ practice in complicated abdominal wounds with or without viscero-cutaneous fistulae.</p></div><div><h3>Methods</h3><p>Retrospective review of children managed by VAC over 5 years, from January 2017 to December 2022. Included patients had complicated abdominal wounds. Customized VAC devices with continuous negative pressure were used for all patients. The applied pressure was tailored according to the patient's age and the wound condition.</p></div><div><h3>Results</h3><p>Nineteen patients were included, their ages ranged from 3 months to 15 years. Peritonitis was the main pathology in 12 patients, abdominal wall infection in 4, and a combination of both in 3. VAC was applied over closed wounds in 10 patients and over open wounds in 9; 6 of them had cutaneous fistulae. The median duration of VAC application over closed wounds was 7.5 days, while it was 10 days in open wounds. VAC promoted healing in closed and narrow-gapped wounds, while it was successfully used as a bridging therapy in 4 patients with wide-gapped wounds. Patients with viscero-cutaneous fistulae were successfully managed without further surgical intervention. VAC was complicated by fascial dehiscence with evisceration and incisional hernia in two patients.</p></div><div><h3>Conclusion</h3><p>VAC could be beneficial to complicated abdominal wounds in pediatric age. It was helpful in managing small viscero-cutaneous fistulae.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"8 ","pages":"Article 100153"},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000388/pdfft?md5=00eb53d8a7f51a71ae6910fd05bd3d26&pid=1-s2.0-S2949711624000388-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141407159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attending physicians and trainees' perspective of patient safety culture in operating room: A mixed methods study","authors":"Nutan B. Hebballi ,&nbsp;Molly P. Kilcullen ,&nbsp;Maryam Broussard ,&nbsp;Madelene J. Ottosen ,&nbsp;Eric J. Thomas ,&nbsp;Eduardo Salas ,&nbsp;KuoJen Tsao","doi":"10.1016/j.yjpso.2024.100152","DOIUrl":"https://doi.org/10.1016/j.yjpso.2024.100152","url":null,"abstract":"<div><h3>Background</h3><p>Regulatory quantitative assessments are routinely undertaken to understand the patient safety culture within an organization. However, adjunctive qualitative approaches to explore low-scoring areas of safety culture in the operating room (OR) are lacking and may provide additional insight. Thus, we explored OR patient safety culture perceptions of pediatric surgical providers, specifically among attending physicians and trainees.</p></div><div><h3>Methods</h3><p>A cross-sectional survey was pilot-tested by pediatric surgical attending physicians and surgical trainees from one academic hospital OR. The “Safer Culture” survey was developed using validated survey measures of concepts from the Safer Culture framework and modified by cognitive interviews with subject-matter experts. The survey was electronically administered, and the results were analyzed descriptively, and percent positive scores were computed. Semi-structured interviews with a purposive sample of participants were then conducted and thematically analyzed.</p></div><div><h3>Results</h3><p>Of the 144 participants, 67 completed the survey (response rate: 46.5 %). <em>Safety competence</em> (&gt;95 %) and <em>individual commitment &amp; prioritization of safety</em> (&gt;90 %) were rated highest by attending physicians and trainees. Trainees rated <em>policies &amp; resources for safety</em> and <em>cohesion</em> the lowest (&lt;60 %). Attending physicians and trainees rated <em>just culture</em> the lowest (&lt;56 %). Interview data revealed three overarching themes explain the lowest ratings: 1) feedback and fear influence incident reporting, 2) lack of accountability and learning affect just culture, and 3) individual and group preparedness impact safe surgical care.</p></div><div><h3>Conclusions</h3><p>Safer Culture survey identified low-performing issues affecting OR safety culture by pediatric surgical providers. Their perceptions specified areas to focus initiatives to improve OR safety culture.</p></div><div><h3>Levels of evidence</h3><p>Level III.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"7 ","pages":"Article 100152"},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000376/pdfft?md5=ecbe8f4567cbbdf6cbc5c319c2deabde&pid=1-s2.0-S2949711624000376-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141315023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-Wilms renal tumors: Twenty years experience in a referral center","authors":"Cristina Garcés-Visier ,&nbsp;Przemyslaw Maruszewski ,&nbsp;Ana Lourdes Luis-Huertas ,&nbsp;Pedro Borrrego-Jimenez ,&nbsp;Daniel Azorín ,&nbsp;Alberto Martín-Vega ,&nbsp;Manuel Espinoza-Vega ,&nbsp;Blanca Herrero-Velasco ,&nbsp;Jose Lorenzo Alonso-Calderón","doi":"10.1016/j.yjpso.2024.100151","DOIUrl":"10.1016/j.yjpso.2024.100151","url":null,"abstract":"<div><h3>Background</h3><p>Non-Wilms Renal Tumors (NWRT) constitute less than 10% of all renal tumors diagnosed in childhood. We studied our experience in the diagnosis and management of these tumors to compare our results with the current literature.</p></div><div><h3>Study design</h3><p>This is a retrospective observational study which includes all patients aged 0-18 years with histopathological diagnosis of NWRT treated in our center during the period 2000-2022.</p></div><div><h3>Results</h3><p>We identified 10 patients with diagnosis of: cystic nephroma(3), congenital mesoblastic nephroma(1), renal cell carcinoma(2), clear cell sarcoma of the kidney (2), renal Ewing's sarcoma(1) and malignant rhabdoid tumor of the kidney(1). Sixty percent (60%) were female. The median age at diagnosis was 3.25 years (IQR 1.5-10). Median age at diagnosis excluding CN was 6 years old (IQR 2.62-10.75). Molecular alterations were detected in 60% of the cases. Hematuria (40%) and palpable abdominal mass (40%) were the most frequent presenting symptoms. In total, 62.5% patients were misdiagnosed during the preoperative period as Wilms' tumor (WT), based on imaging data. <del>A</del> Radical nephroureterectomy was performed in all cases and staging lymphadenectomy in 70%. We recorded a major complication in one patient, who suffered a contralateral lower renal pole infarction due to section of a polar vessel during surgery. This patient had no preoperative vascular study. The recurrence-free survival rate was 90% with a median follow-up of 6.4 years (IQR 2-13.9).</p></div><div><h3>Discussion</h3><p>Radiological imaging has fundamental importance in the diagnosis of renal tumors, especially to identify children who might benefit from initial surgical treatment or the indication of biopsy for preoperative histopathological confirmation before initiating cytotoxic treatment. However, there are no pathognomonic imaging findings that clearly differentiate between WT and other renal tumors, nor among the heterogeneous group of NWRT[<span><span>3</span></span>]. In our series, 62.5% of patients were misdiagnosed as WT based on imaging features.</p><p>We found different molecular alterations in 60% of our patients (Table 1). None of them predispose to the development of bilateral tumors nor correlates with predisposing syndromes of metachronous tumors.</p><p>Apart from its retrospective design, this study is limited by small number of cases and a long study period.</p></div><div><h3>Conclusions</h3><p>Correct differential diagnosis of NWRT is necessary for an adequate therapeutic approach. The molecular-genetic profile is an important step in the diagnosis of NWRT that allows for the use of targeted therapies in refractory patients. Detailed anatomical study by vascular mapping minimizes the risk of iatrogenic damage during tumor resection.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"8 ","pages":"Article 100151"},"PeriodicalIF":0.0,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000364/pdfft?md5=83215d0377f5c8331eba5eab9dcffb06&pid=1-s2.0-S2949711624000364-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141959401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The surgical management of peripheral IV extravasation injuries in infants and children","authors":"Genevieve Kierulf ,&nbsp;Nicole Becher ,&nbsp;Adam Goldsmith ,&nbsp;Young Mee Choi ,&nbsp;Steven Moulton","doi":"10.1016/j.yjpso.2024.100150","DOIUrl":"https://doi.org/10.1016/j.yjpso.2024.100150","url":null,"abstract":"<div><h3>Introduction</h3><p>Peripheral IV extravasation (PIVE) injuries are a common cause of skin injury in infants and children. Although most PIVE injuries are minor and self-limited, severe PIVE injuries associated with calcium deposition and/or full-thickness skin injury will require surgical management.</p></div><div><h3>Methods</h3><p>This is a retrospective review of children with PIVE injures who required surgical management at our institution from 2012 to 2022. Data collected included demographics, substance infiltrated, immediate management, surgical history, and long-term outcomes. Immediate management for those at imminent risk for skin loss or circulation impairment involved treatment with hyaluronidase to minimize tissue damage, followed by removal of the IV catheter. PIVEs involving calcium containing infiltrates were observed for 2–4 weeks to allow the calcium to precipitate, before undertaking surgical debridement of calcium deposits.</p></div><div><h3>Results</h3><p>There were 11 PIVE injuries requiring surgery during the 10-year study period, of which 7 (63.6 %) were infants (&lt; 30 days old). Surgery was delayed 2–4 weeks for those whose infiltrate contained calcium, to allow for precipitation and coalescence of the calcium in the soft tissue. Nine patients required debridement with skin grafting. One patient underwent debridement with wound closure, and one underwent needle decompression alone. Eight patients (72.7 %) received follow-up from OT/PT services, and most (75 %) achieved optimal functional outcomes including full range of motion and age-appropriate motor skills.</p></div><div><h3>Conclusions</h3><p>Most IV infiltrate injuries self-resolve with no sequelae. Those injuries caused by calcium containing fluids or caustic medications can result in significant tissue destruction requiring operative intervention.</p></div><div><h3>Level of Evidence</h3><p>Treatment Study, Level IV</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"7 ","pages":"Article 100150"},"PeriodicalIF":0.0,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000352/pdfft?md5=6ed25579ffdc74b160a2487300f865e0&pid=1-s2.0-S2949711624000352-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141244505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rebooting the anal sphincter: A retrospective cohort of children with intractable constipation receiving intrasphincteric botox injections","authors":"Luke Uden ,&nbsp;Mansha Jiwane ,&nbsp;Jyoti R Sharma ,&nbsp;Ajay Sharma ,&nbsp;Daisy Evans ,&nbsp;Britta S von Ungern-Sternberg ,&nbsp;Parshotam Gera","doi":"10.1016/j.yjpso.2024.100147","DOIUrl":"10.1016/j.yjpso.2024.100147","url":null,"abstract":"<div><h3>Background</h3><p>Chronic childhood constipation is a common problem that severely impacts quality of life. Recently, the efficacy of intrasphincteric botulinum toxin (botox) injection in breaking the cycle of constipation has been demonstrated. The current study aims to investigate response rate to treatment, symptom and examination finding associations, and identify associations between patient characteristics and outcome.</p></div><div><h3>Methods</h3><p>Parental consent was given for the review of medical records. This retrospective cohort included paediatric patients, under 16 years old, presenting to Perth Paediatrics, in Western Australia, from August 2017 to June 2022, who received botox injections (10 IU/kg, at 3, 6, and 9 o'clock) for intractable constipation. Patients required a negative diagnosis of Hirschsprung's disease for inclusion. A successful outcome was defined by a reduction in related symptoms and dosage of aperients at a post-operative consultation at least two weeks following injection, compared to those prior.</p></div><div><h3>Results</h3><p>Of 81 patients, 83 % experienced an overall improvement in symptoms following their first injection. 47 % noted a reduced laxative requirement, with no patients reporting any adverse effects. Twelve patients received a second injection, of which 58 % reported a successful outcome afterward. Across all variables, the majority of patients experienced a positive response. In this retrospective cohort, there were no associations demonstrated between comorbidities, age, sex, symptomatology, or examination findings, and positive response.</p></div><div><h3>Conclusions</h3><p>These results suggest that, in managing intractable constipation in children, intrasphincteric botox injection may be beneficial in reducing symptoms, with no reported adverse events in this cohort.</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"7 ","pages":"Article 100147"},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000327/pdfft?md5=440447d85d6ed24c8bbd2002b557a537&pid=1-s2.0-S2949711624000327-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141037147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a tool to assess patient and caregiver satisfaction for minor pediatric surgical procedures","authors":"Karan Gandhi ,&nbsp;Jacob Davidson ,&nbsp;Camille Duggal ,&nbsp;Vanessa Fantillo ,&nbsp;Julie E. Strychowsky","doi":"10.1016/j.yjpso.2024.100145","DOIUrl":"10.1016/j.yjpso.2024.100145","url":null,"abstract":"<div><h3>Introduction</h3><p>Patient satisfaction questionnaires offer valuable perspectives on patient experiences and the quality of healthcare received. Despite their importance, a gold standard for measuring patient satisfaction in pediatric surgery remains elusive. This study introduces a patient satisfaction questionnaire designed to fill the gap in evaluating patient experiences specifically in pediatric surgical settings, aiming to create a standardized measure for assessing patient satisfaction.</p></div><div><h3>Methods</h3><p>The think-aloud method was used with patient advisors and an expert panel of hospital stakeholders to refine a novel patient and caregiver satisfaction tool. Through an iterative process, data was gathered, analyzed and the survey progressively revised. The final survey was then pilot tested.</p></div><div><h3>Results</h3><p>Three patient advisors and seven hospital stakeholders participated in the study. The think-aloud method was used to establish cognitive, content, and face validity. There were five distinct satisfaction domains established. Pilot testing included 30 participants and was used to establish construct validity and test-retest reliability.</p></div><div><h3>Conclusions</h3><p>This study addresses the existing gap in measuring patient satisfaction in pediatric surgery settings. The think-aloud method was used to ensure cognitive, content, and face validity ensuring multiple domains are addressed. Pilot testing of the tool showed feasibility in both the operating room and minor procedure room setting while also demonstrating test re-test validity. These results indicate that this questionnaire holds promise for use in a variety of pediatric surgical settings. Further research is necessary to confirm these findings in larger, more diverse populations and to assess its impact on improving patient care and experiences.</p></div><div><h3>Type of Study</h3><p>Survey Development and Validation Study.</p></div><div><h3>Level of Evidence</h3><p>III</p></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"7 ","pages":"Article 100145"},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949711624000303/pdfft?md5=7eaa504cc593bfe3d07aed1f41c7b11e&pid=1-s2.0-S2949711624000303-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141031138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}