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Seasonal trends and risk factors in prosthetic joint infections: A retrospective analysis 假体关节感染的季节性趋势和危险因素:回顾性分析
Journal of Orthopaedic Reports Pub Date : 2025-03-27 DOI: 10.1016/j.jorep.2025.100656
Mars Yixing Zhao , Evan Parchomchuk , Thomas Goldade , Mikayla Rudniski , Nathan Oster , Mason Beaulieu , Michaela Nickol , Johannes M. van der Merwe
{"title":"Seasonal trends and risk factors in prosthetic joint infections: A retrospective analysis","authors":"Mars Yixing Zhao ,&nbsp;Evan Parchomchuk ,&nbsp;Thomas Goldade ,&nbsp;Mikayla Rudniski ,&nbsp;Nathan Oster ,&nbsp;Mason Beaulieu ,&nbsp;Michaela Nickol ,&nbsp;Johannes M. van der Merwe","doi":"10.1016/j.jorep.2025.100656","DOIUrl":"10.1016/j.jorep.2025.100656","url":null,"abstract":"<div><h3>Purpose</h3><div>Prior studies on the seasonal influence have yielded mixed results, with European studies linking warmer seasons to increased PJI rates, while North American data are less conclusive. We tried to determine if different seasons effect the incidence of acute and chronic PJIs. In addition we aimed to investigate if there was a correlation between PJI and age, BMI, surgeon, operating times, operating rooms, Diabetes, RA, end stage renal disease, congestive heart failure, alcohol or drug abuse, Charlson comorbidity index, surgical assist and ASA score.</div></div><div><h3>Methods</h3><div>A single-center retrospective review was conducted on patients with PJIs at a tertiary center from April 2012 to May 2024. A total of 114 cases of PJI were analyzed and data collection included demographic, comorbidity, and surgical details such as season of surgery, body mass index (BMI), age, surgeon, assistant, operating room nurses, comorbidities, anesthesia type, and postoperative anticoagulation.</div></div><div><h3>Results</h3><div>Among 114 patients with PJIs, acute PJIs were more common in winter (28 %) and summer (26 %), though findings were not statistically significant (p = 0.596). Late PJIs had higher prevalence in winter and fall (31 %) (p = 0.596). THA patients were more likely to experience acute PJI, whereas late PJI was more common in TKA patients (p = 0.002). We did find a “somewhat strong” association between the individual surgeons and the occurrence of PJI's (Cramer's V = 0.498). The majority of patients in the acute PJI had an ASA score of≥2, while the majority of patients in the late PJI group had an ASA score of 2 (p = 0.031).</div></div><div><h3>Conclusion</h3><div>Acute prosthetic joint infections (PJI) were found to occur more frequently in winter and summer, while late PJIs occurred more often in fall and winter, though the differences were not statistically significant. Acute PJIs were more common in total hip arthroplasties (THAs) and associated with an ASA score ≥2, while late PJIs were primarily seen in total knee arthroplasties (TKAs) with an ASA score of 2. No correlation was identified between PJIs and factors such as BMI, age, operating conditions, or comorbidities like diabetes, COPD, or rheumatoid arthritis.</div></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 2","pages":"Article 100656"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tibial tubercle osteotomy for the exposure of complex primary and revision Total Knee Arthroplasty- our 21 years of experience 胫骨结节截骨术暴露复杂的初级和翻修全膝关节置换术-我们21年的经验
Journal of Orthopaedic Reports Pub Date : 2025-03-27 DOI: 10.1016/j.jorep.2025.100631
Ameya Katariya, P. Suryanarayan, Vijay Bose, P.S. Ashok Kumar, Kalaivanan Kanniyan, Shantanu Patil
{"title":"Tibial tubercle osteotomy for the exposure of complex primary and revision Total Knee Arthroplasty- our 21 years of experience","authors":"Ameya Katariya,&nbsp;P. Suryanarayan,&nbsp;Vijay Bose,&nbsp;P.S. Ashok Kumar,&nbsp;Kalaivanan Kanniyan,&nbsp;Shantanu Patil","doi":"10.1016/j.jorep.2025.100631","DOIUrl":"10.1016/j.jorep.2025.100631","url":null,"abstract":"<div><h3>Background</h3><div>Adequate exposure is often challenging in complex primary and revision Total Knee Arthroplasty (TKA). A quadriceps snip in addition to a standard approach is the most widely used approach in such cases. Tibial tubercle osteotomy (TTO) becomes an attractive option where a quadriceps snip is inadequate and a more extensile approach is required. However, due to multiple reported complications and lack of clear consensus regarding surgical technique, there is reluctance to the use of this approach.</div></div><div><h3>Methods</h3><div>We retrospectively analysed 30 cases of TTO operated between January 2002 to January 2023, by two surgeons but with the same surgical technique and rehabilitation protocol. Study included 9 cases of complex primary and 21 cases of revision TKAs. Mean age was 57 years (29–77 years) with a mean follow up of 14 years (3–21 years). Rehabilitation was individualised according to wound status and function. At follow ups knee range of motion, extensor lag, mobility status, gait, status of the wound, osteotomy union rate and proximal migration was recorded.</div></div><div><h3>Results</h3><div>Arc of motion improved from a mean 42° (Range, 15 to 60) preoperatively to a mean 89° (Range, 50 to 110) post operatively. 29 osteotomies (96.66 %) united in a mean duration of 4.6 months (1.5–8 months). Two patients (6.66 %) had extensor lag with a mean of 10°. Five osteotomies (16.66 %) had proximal migration with a mean of 4 mm (2–6 mm) and two cases (6.66 %) had patella Baja. No wound healing problems, dehiscence or fractures were reported in early and late post-operative period.</div></div><div><h3>Conclusion</h3><div>TTO is an effective, safe and reliable approach for a complex primary or revision TKA. However, good surgical technique and titrated rehabilitation program remain the key to achieve good post-operative function and minimise complications.</div></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 2","pages":"Article 100631"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knee megaprosthesis: Analysis of clinical outcomes, complications, and implant survival across complex indications 膝关节巨型假体:临床结果、并发症和复杂适应症的假体存活分析
Journal of Orthopaedic Reports Pub Date : 2025-03-26 DOI: 10.1016/j.jorep.2025.100632
Yassine Ben Bouzid, Moulay Omar Lamrani
{"title":"Knee megaprosthesis: Analysis of clinical outcomes, complications, and implant survival across complex indications","authors":"Yassine Ben Bouzid,&nbsp;Moulay Omar Lamrani","doi":"10.1016/j.jorep.2025.100632","DOIUrl":"10.1016/j.jorep.2025.100632","url":null,"abstract":"<div><h3>Background</h3><div>Knee megaprosthesis are an essential solution for managing complex pathologies, including peri-prosthetic fractures and tumor resections. However, their application is frequently associated with high rates of mechanical and infectious complications, necessitating thorough evaluation of functional outcomes and implant survival rates.</div></div><div><h3>Materials and methods</h3><div>This retrospective study included 28 patients who underwent knee megaprosthesis for complex fractures, pseudarthrosis or tumor-related indications. Functional outcomes were assessed using the Knee Society Score (KSS) and the Knee Society Functional Score (KSKF). Complications were classified according to Henderson's classification, and implant survival rates were calculated based on a mean follow-up of 3.7 years.</div></div><div><h3>Results</h3><div>The gross survival rate of the implants was 51.5 %, while the adjusted survival rate was 42.9 %. Infectious complications were observed in 17.8 % of cases, and mechanical failures occurred in 7.1 %. Postoperative functional scores demonstrated moderate improvement, although limitations remained common among patients who experienced complications.</div></div><div><h3>Conclusion</h3><div>Knee megaprosthesis provide a viable solution for complex knee pathologies but carry a significant risk of complications. Rigorous patient selection, implant customization strategies, and optimized follow-up protocols are crucial to improving long-term outcomes.</div></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 2","pages":"Article 100632"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143816170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of four types of patellofemoral ONLAY prostheses: Is there superiority of one design over another? 四种类型髌骨ONLAY假体的比较研究:一种设计是否优于另一种?
Journal of Orthopaedic Reports Pub Date : 2025-03-18 DOI: 10.1016/j.jorep.2025.100625
Pablo Ramos Guarderas , Gonzalo Arteaga Guerrero , Medardo Vargas Morante , Pablo Ramos Murrillo , Carlos Peñaherrera Carrillo , Francisco Endara Urresta , David Ramos Murillo , Alejandro Barros Castro , Paul Vaca Perez
{"title":"Comparative study of four types of patellofemoral ONLAY prostheses: Is there superiority of one design over another?","authors":"Pablo Ramos Guarderas ,&nbsp;Gonzalo Arteaga Guerrero ,&nbsp;Medardo Vargas Morante ,&nbsp;Pablo Ramos Murrillo ,&nbsp;Carlos Peñaherrera Carrillo ,&nbsp;Francisco Endara Urresta ,&nbsp;David Ramos Murillo ,&nbsp;Alejandro Barros Castro ,&nbsp;Paul Vaca Perez","doi":"10.1016/j.jorep.2025.100625","DOIUrl":"10.1016/j.jorep.2025.100625","url":null,"abstract":"<div><h3>Introduction</h3><div>Patellofemoral osteoarthritis (PFOA) has been associated with anterior knee pain, stiffness, and functional impairment. The incidence of PFOA ranges from 2 % to 24 % in individuals over 55 years old. The development of PFOA has been linked to abnormal stress on the patellofemoral joint. The treatment of PFOA includes both non-surgical and surgical options. In severe cases that do not respond to conservative management, patellofemoral arthroplasty (PFA) is indicated. PFA has been utilized for approximately 14 years in the studied institution, achieving optimal outcomes in 96.6 % of cases and a conversion rate to total knee arthroplasty of 3.4 % in a cohort of 256 patients. Four different types of prostheses have been used (AVON Stryker, VANGUARD Biomet, JOURNEY Smith &amp; Nephew, and GENDER PF Zimmer–Biomet), prompting this comparative study of different ONLAY-type PFA designs.</div></div><div><h3>Materials and methods</h3><div>A retrospective observational study was conducted involving 256 patients diagnosed with primary Grade IV patellofemoral osteoarthritis. These patients were treated with four different ONLAY PFA designs. The cohort consisted of 77 % females and 23 % males, with a mean age of 52.2 years and a follow-up period of one year. The objective was to evaluate if one design demonstrated superiority over the others.</div></div><div><h3>Results</h3><div>Comparative tables of the different prosthesis models were created, detailing their advantages and disadvantages. These results were contrasted with patient satisfaction indexes measured by the Forgotten Joint Score, and quality-adjusted life years (QALYs) were applied to determine which implant model best suited patients' needs and lifestyles.</div></div><div><h3>Conclusions</h3><div>The results showed high patient satisfaction and improvements in daily and sports activities. The GENDER™ implant was found to be the most recommended based on the combination of the evaluated variables.</div></div><div><h3>Level of evidence</h3><div>IV.</div></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 2","pages":"Article 100625"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical outcomes of the surgical treatment of acetabular fractures 髋臼骨折手术治疗的临床效果
Journal of Orthopaedic Reports Pub Date : 2025-03-17 DOI: 10.1016/j.jorep.2025.100626
Udomsin Singjam, Thananit Sangkomkamhang, Wanjak Pongsmakthai
{"title":"Clinical outcomes of the surgical treatment of acetabular fractures","authors":"Udomsin Singjam,&nbsp;Thananit Sangkomkamhang,&nbsp;Wanjak Pongsmakthai","doi":"10.1016/j.jorep.2025.100626","DOIUrl":"10.1016/j.jorep.2025.100626","url":null,"abstract":"<div><h3>Background</h3><div>This study aimed to evaluate the clinical outcomes of surgical treatment for acetabular fractures and identify predictive factors associated with favorable results.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted on 156 patients who underwent surgical treatment for acetabular fractures at Khon Kaen Hospital between January 2017 and December 2021. Data collected included demographic characteristics, cause of injury, fracture classification (Judet and Letournel system), presence of associated hip dislocation, time to surgery, and quality of reduction (assessed using Matta's criteria). Clinical outcomes were evaluated at 12 months postoperatively using the Merle d'Aubigné Hip score. Univariate and multivariate logistic regression analyses were performed to identify significant predictors of very good clinical outcomes.</div></div><div><h3>Results</h3><div>The cohort comprised 134 males (85.9 %) and 22 females (14.1 %) with a mean age of 42.71 years. The leading cause of injury was traffic accidents (78.85 %), followed by falls from height (21.15 %). Fractures were classified as elementary (47.44 %) or associated (52.56 %), with associated hip dislocation present in 41.03 % of the cases. Very good clinical outcomes were observed in 56.41 % of the patients. Univariate analysis revealed that early surgical intervention (≤14 days) (p = 0.024), absence of associated hip dislocation (p = 0.000), and high-quality reduction (≤3 mm displacement) (p = 0.000) were significantly associated with better outcomes. Multivariate analysis confirmed these factors as independent predictors of favorable results. Age and fracture classification were not significantly associated with clinical outcomes.</div></div><div><h3>Conclusion</h3><div>Timely surgical intervention, high-quality fracture reduction, and the absence of associated hip dislocation are crucial predictors of successful clinical outcomes following acetabular fracture surgery. These findings highlight the significance of early and precise surgical management in optimizing patient recovery.</div></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 2","pages":"Article 100626"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143816172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes and complications of shoulder arthroplasty in patients with celiac disease: A large insurance claims matched cohort analysis 乳糜泻患者肩关节置换术的结果和并发症:一项大型保险索赔匹配队列分析
Journal of Orthopaedic Reports Pub Date : 2025-03-17 DOI: 10.1016/j.jorep.2025.100627
Camden Bohn, Catherine Hand, Chase Gornbein, Harmanjeet Singh, Daanish Khazi-Syed, Josh Chang, Brian Forsythe
{"title":"Outcomes and complications of shoulder arthroplasty in patients with celiac disease: A large insurance claims matched cohort analysis","authors":"Camden Bohn,&nbsp;Catherine Hand,&nbsp;Chase Gornbein,&nbsp;Harmanjeet Singh,&nbsp;Daanish Khazi-Syed,&nbsp;Josh Chang,&nbsp;Brian Forsythe","doi":"10.1016/j.jorep.2025.100627","DOIUrl":"10.1016/j.jorep.2025.100627","url":null,"abstract":"<div><h3>Introduction</h3><div>Celiac disease (CD) is an autoimmune enteropathy with systemic effects, including impaired bone and joint health. While CD has been linked to adverse outcomes in lower extremity arthroplasty, its impact on shoulder arthroplasty remains unexplored. This study aims to characterize postoperative outcomes and complications in CD patients undergoing shoulder arthroplasty, hypothesizing that CD patients will experience higher complication rates compared to matched controls.</div></div><div><h3>Methods</h3><div>A retrospective matched cohort analysis was conducted using the PearlDiver national insurance claims database. Patients who underwent primary anatomic, reverse, or hemiarthroplasty between 2010 and 2020 were identified. CD patients were matched 1:2 to controls based on age, sex, and Elixhauser Comorbidity Index (ECI). Primary outcomes included revision arthroplasty and rotator cuff repair (RCR). Secondary outcomes encompassed 90-day complications, including infections, emergency department (ED) visits, acute kidney injury, pneumonia, pulmonary embolism, and urinary tract infection. Multivariate regression analysis was performed to adjust for confounders.</div></div><div><h3>Results</h3><div>Among 191,178 shoulder arthroplasty patients, 739 (0.4 %) had CD. The final cohorts included 733 CD patients and 1460 matched controls. CD patients had significantly higher odds of 90-day complications, including infection (OR 2.7, <em>p</em> &lt; 0.001), ED visits (OR 2.4, <em>p</em> &lt; 0.001), acute kidney injury (OR 2.1, <em>p</em> = 0.006), pneumonia (OR 2.6, <em>p</em> &lt; 0.001), pulmonary embolism (OR 5.4, <em>p</em> &lt; 0.001), and urinary tract infection (OR 3.8, <em>p</em> &lt; 0.001). However, revision arthroplasty (OR 0.9, <em>p</em> = 0.572) and post-arthroplasty RCR rates (OR 1.1, <em>p</em> = 0.606) were comparable between groups.</div></div><div><h3>Conclusion</h3><div>CD is associated with an increased risk of short-term complications following shoulder arthroplasty but does not appear to influence revision or RCR rates. These findings highlight the need for heightened perioperative vigilance in CD patients undergoing shoulder arthroplasty to mitigate potential complications.</div></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 2","pages":"Article 100627"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of clinical outcomes in acute versus staged open reduction-internal fixation of OTA/AO type 43C tibial pilon fractures OTA/AO型43C胫骨pilon骨折急性与分期切开复位内固定的临床疗效比较
Journal of Orthopaedic Reports Pub Date : 2025-03-17 DOI: 10.1016/j.jorep.2025.100646
Austin C. Stewart , Richard Phan , Thomas Cho , Jiayong Liu , Chris G. Sanford
{"title":"Comparison of clinical outcomes in acute versus staged open reduction-internal fixation of OTA/AO type 43C tibial pilon fractures","authors":"Austin C. Stewart ,&nbsp;Richard Phan ,&nbsp;Thomas Cho ,&nbsp;Jiayong Liu ,&nbsp;Chris G. Sanford","doi":"10.1016/j.jorep.2025.100646","DOIUrl":"10.1016/j.jorep.2025.100646","url":null,"abstract":"<div><h3>Introduction</h3><div>AO/OTA Type 43C tibial pilon fractures are severe high-energy injuries of the distal tibia, marked by complete articular disruption and separation from the tibial diaphysis. These injuries present significant treatment challenges due to extensive soft tissue damage and articular comminution, often resulting in functional impairments and high rates of complications. Traditionally, delayed two-stage Open Reduction-Internal Fixation (sORIF) has been the standard treatment, involving initial external fixation followed by definitive fixation. However, recent studies suggest that acute one-stage ORIF (aORIF) achieves similar outcomes, though direct comparative evidence between these two approaches remains limited. This study quantitatively evaluates post-operative complications and clinical outcomes between aORIF and sORIF for AO/OTA Type 43C fractures, hypothesizing that both strategies yield comparable results.</div></div><div><h3>Methods</h3><div>A systematic review and meta-analysis were conducted comparing aORIF and sORIF for AO/OTA Type 43C fractures. Databases (PubMed, Google Scholar, EndNote) were searched using “open reduction and internal fixation,” “AO/OTA 43C,” and “tibial pilon fracture.” Retrospective studies with a minimum 6-month follow-up were included if they compared aORIF (fixation &lt;48 h) and sORIF (fixation ≥7 days). Primary outcomes included infection (superficial and deep), non-union, delayed union/malunion, wound dehiscence, and post-operative osteoarthritis. Meta-analysis using RStudio calculated risk ratios (RR) with 95 % confidence intervals (CI).</div></div><div><h3>Results</h3><div>Five direct comparison studies involving 679 patients (452 males, 227 females; mean age 43.92 years) were included, with 256 undergoing aORIF and 423 sORIF. Among these, 202 were open fractures and 477 were closed. The meta-analysis indicated that aORIF significantly reduced overall infection risk compared to sORIF (RR 0.65, 95 % CI [0.45, 0.92], p = 0.018). No significant differences were observed for deep infection, superficial infection, wound dehiscence, non-union, delayed union/malunion, or post-operative osteoarthritis.</div></div><div><h3>Conclusions</h3><div>aORIF demonstrates comparable outcomes to sORIF and lower infection rates, suggesting it is a viable option for AO/OTA Type 43C fractures. Adoption of aORIF may reduce treatment duration and recovery time. Future research should consider additional variables, such as Burnwell-Charnley Anatomic Reduction, AOFAS Ankle-Hindfoot Functional Scores, hospital length of stay, operation time, and fracture subtype (i.e., 43C1, 43C2, 43C3) for a more comprehensive evaluation of treatment strategies.</div></div><div><h3>Level of evidence</h3><div>III.</div></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 2","pages":"Article 100646"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of advanced demineralized bone fiber graft forms in rabbit posterolateral spine fusion: A feasibility study 兔脊柱后外侧融合术中高级脱矿物质骨纤维移植形式的评估:可行性研究
Journal of Orthopaedic Reports Pub Date : 2025-03-17 DOI: 10.1016/j.jorep.2025.100634
Nelson Scarborough , Hania Shahzad , Brian Barnes , Safdar N. Khan
{"title":"Assessment of advanced demineralized bone fiber graft forms in rabbit posterolateral spine fusion: A feasibility study","authors":"Nelson Scarborough ,&nbsp;Hania Shahzad ,&nbsp;Brian Barnes ,&nbsp;Safdar N. Khan","doi":"10.1016/j.jorep.2025.100634","DOIUrl":"10.1016/j.jorep.2025.100634","url":null,"abstract":"<div><h3>Background</h3><div>Fibrant Fibers (FF) are a new type of demineralized bone fibers (DBF) that enable the production of novel graft forms such as the cylindrical graft Pak. The objective of this study was to evaluate the fusion rates of combinations of FF and Pak with autograft iliac crest bone graft (ICBG) and bone marrow aspirate (BMA) in a challenging posterolateral rabbit fusion model.<sup>1</sup> These grafts are designed to create a continuous matrix across the fusion site, and easily incorporate autograft and BMA, acting as autograft extenders or substitutes when used with BMA.</div></div><div><h3>Methods</h3><div>This feasibility study was conducted, recruiting eleven healthy, skeletally mature female white New Zealand rabbits who were randomly assigned to three groups: Group 1 received ICBG and FF, Group 2 received ICBG placed inside Pak, and Group 3 received FF rehydrated with BMA and placed inside FB. For each animal, grafts were implanted bilaterally along the transverse processes (TP). Primary outcomes were fusion rates assessed by manual palpation, radiographs, and 3D uCT images at 8 weeks.</div></div><div><h3>Results</h3><div>All 11 animals successfully recovered from surgery. Fusion rates were found to be 91 % using manual palpation, with 100 % fusion observed in Group 1 and Group 3. Radiological evaluation showed fusion rates of 100 % for Group 1, 100 % for Group 3, and 90 % for Group 2. Micro CT evaluation revealed fusion rates of 100 % for all three groups. The quality of fusion was found to be robust across all three groups based on histological evaluation.</div></div><div><h3>Conclusions</h3><div>The results of this feasibility study demonstrate the potential of DBF forms of FF, particularly when combined with BMA, shows promise as an effective alternative or adjunct to traditional autografts. The findings suggest that these graft forms could be highly beneficial in clinical settings, providing surgeons with more versatile and potentially more effective options for spinal fusion procedures.</div></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 2","pages":"Article 100634"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathological fractures in primary bone sarcomas: A review article 原发性骨肉瘤的病理性骨折:一篇综述文章
Journal of Orthopaedic Reports Pub Date : 2025-03-17 DOI: 10.1016/j.jorep.2025.100628
Philani Ntombela, Wofhatwa Ndou
{"title":"Pathological fractures in primary bone sarcomas: A review article","authors":"Philani Ntombela,&nbsp;Wofhatwa Ndou","doi":"10.1016/j.jorep.2025.100628","DOIUrl":"10.1016/j.jorep.2025.100628","url":null,"abstract":"<div><h3>Introduction</h3><div>The treatment of pathological fractures in malignant primary bone sarcomas remains a question open for debate. They constitute 5 %–10 % of patients diagnosed with malignant primary bone sarcomas. This article reviews the latest available literature on the management of pathological fractures in patients with bone sarcomas.</div></div><div><h3>Discussion</h3><div>The options for temporary fracture treatment during chemotherapy include closed immobilization (skin traction, plaster cast, orthosis), internal fixation and external fixation and none of the options show increased risk of local recurrence. The widely accepted chemotherapy guidelines are those described by the National Comprehensive Cancer Network and the European Society for Medical Oncology, European Reference Network for Paediatric Cancers, and European Network for Rare Adult Solid Cancer. Definitive surgery must be cognizant of 4 factors: i) the objective of the surgery as guided by the overall treatment principle i.e. curative or palliative; ii) the available resources and facilities; iii) patient values and physiologic status; iv) surgeon's expertise.</div></div><div><h3>Conclusion</h3><div>Limb salvage is a safe and viable option for pathological fractures however, patients with pathological fractures have a worse overall survival rate.</div></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 2","pages":"Article 100628"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A specific dual-mobility prosthesis design in trapeziometacarpal joint osteoarthritis 一种特殊的双活动假体设计用于治疗斜跖骨关节炎
Journal of Orthopaedic Reports Pub Date : 2025-03-15 DOI: 10.1016/j.jorep.2025.100630
Giuseppe Rovere , Francesco Bosco , Alessio Cioffi , Fortunato Giustra , Francesco Liuzza , Lawrence Camarda
{"title":"A specific dual-mobility prosthesis design in trapeziometacarpal joint osteoarthritis","authors":"Giuseppe Rovere ,&nbsp;Francesco Bosco ,&nbsp;Alessio Cioffi ,&nbsp;Fortunato Giustra ,&nbsp;Francesco Liuzza ,&nbsp;Lawrence Camarda","doi":"10.1016/j.jorep.2025.100630","DOIUrl":"10.1016/j.jorep.2025.100630","url":null,"abstract":"<div><h3>Purpose</h3><div>Many prosthetic designs have been developed for treated trapeziometacarpal joint (TMJ) osteoarthritis (OA). The aim of the study was to analyze the clinical, functional, and radiological outcomes and complications of a specific dual-mobility prosthesis for TMJ OA to support the correct hand surgeon decision.</div></div><div><h3>Methods</h3><div>Between January 2019 and January 2022, a retrospective study was conducted on a consecutive series of 14 patients affected by TMJ OA and treated with the implantation of TOUCH® dual mobility TMJ prosthesis (KeriMedical Switzerland-HQ, Geneve, Switzerland). The follow-up period was 12–36 months. Evaluation criteria included the trapeziometacarpal axis, the Visual Analogue Scale (VAS), the pulp-to-pulp modified pinch test, the Kapandji score, and the Michigan Hand Outcomes Questionnaire (MHQ).</div></div><div><h3>Results</h3><div>Clinical, functional, and radiological improvements were found in all outcomes analyzed. The postoperative values of VAS and pulp-to-pulp modified pinch test were statistically significant (p &lt; 0.05). A non-statistically significant postoperative improvement was found in the Kapandji score (p &lt; 0.05). Regarding complications, only one EPL injury was found, but no infection or prosthetic dislocation.</div></div><div><h3>Conclusions</h3><div>The use of a TOUCH® dual-mobility prosthesis for treating TMJ OA improved postoperative clinical, functional, and radiological outcomes with a lower rate of complications in a short-term follow-up.</div></div><div><h3>Level of evidence</h3><div>IV.</div></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 2","pages":"Article 100630"},"PeriodicalIF":0.0,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143816161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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