International Medical Review on Down Syndrome最新文献_第7页

XXX Anniversary of the LISMI LISMI成立三十周年

International Medical Review on Down Syndrome Pub Date : 2012-05-01 DOI: 10.1016/S2171-9748(12)70020-X

K. Trias Trueta

引用次数: 0

Francesc Abel and bioethics 弗朗西斯·阿贝尔与生物伦理学

International Medical Review on Down Syndrome Pub Date : 2012-05-01 DOI: 10.1016/S2171-9748(12)70023-5

J.C. González Casanova

引用次数: 0

Body mass index changes and lipid peroxidation in adults with Down's syndrome 唐氏综合征成人体重指数变化与脂质过氧化

International Medical Review on Down Syndrome Pub Date : 2012-05-01 DOI: 10.1016/S2171-9748(12)70021-1

C.J. Chávez , P. Ortega , A. D’Escrivan , L.E. Miranda , J.Y. Leal M , C. Delgado

{"title":"Body mass index changes and lipid peroxidation in adults with Down's syndrome","authors":"C.J. Chávez , P. Ortega , A. D’Escrivan , L.E. Miranda , J.Y. Leal M , C. Delgado","doi":"10.1016/S2171-9748(12)70021-1","DOIUrl":"https://doi.org/10.1016/S2171-9748(12)70021-1","url":null,"abstract":"<div><h3>Introduction and objective</h3><p>Trisomy 21 or Down's syndrome (DS) is the most common cause of mental retardation of chromosomal origin, in which obesity is a public health problem. Obesity is a pro-oxidant state associated with lipid peroxidation and alterations of antioxidant mechanisms. The effect of gene dosage has been linked to oxidative stress in DS. The objective of this study was to determine the status of lipid peroxidation and changes in body mass index (BMI) in adults with DS.</p></div><div><h3>Patients and method</h3><p>A prospective and cross-sectional study was conducted on 50 adult subjects (31.0±6.3 years) with normal karyotype (NK) and 29 adults with DS (28.0±8.7 years), randomly selected.The serum levels of malondialdehyde (MDA) were analysed by thiobarbituric acid derivatives. The BMI was determined in adults with DS. The data were analysed using the SPSS 15 statistical program, using a 95% CI, <em>p</em><.05.</p></div><div><h3>Results</h3><p>Adults with DS showed high concentrations of MDA (0.9±0.7 nmol / ml, <em>p</em><.009) compared to adult NK group (0.5±0.4 nmol / ml). Abnormality was observed in 72.4% of BMI (n=21) of adults with DS. Elevated concentrations of MDA (1.3±1.0 nmol / ml) were seen in adults with DS and overweight (BMI=27.5±1.3), showing no significant decrease in obese adults with DS.</p></div><div><h3>Conclusion</h3><p>Although a reduction of antioxidant enzymes in severely obese adults without DS has been reported, the effect of gene dosage may be a contributing factor in reducing lipid peroxidation in obese adults with DS, without being a protective factor of its pathological consequences.</p></div>","PeriodicalId":100720,"journal":{"name":"International Medical Review on Down Syndrome","volume":"16 2","pages":"Pages 19-25"},"PeriodicalIF":0.0,"publicationDate":"2012-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2171-9748(12)70021-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72282012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Extreme malnutrition in an infant of Ethiopian origin with Down's syndrome 患有唐氏综合症的埃塞俄比亚裔婴儿极度营养不良

International Medical Review on Down Syndrome Pub Date : 2012-05-01 DOI: 10.1016/S2171-9748(12)70022-3

A. Parri , H. Segurola , M. Villatoro , A. Goday , J. Parri

引用次数: 0

Body mass index changes and lipid peroxidation in adults with Down's syndrome 唐氏综合征成人体重指数变化与脂质过氧化

International Medical Review on Down Syndrome Pub Date : 2012-05-01 DOI: 10.1016/S2171-9748(12)70021-1

C. Chávez, P. Ortega, A. D’Escrivan, L. E. Miranda, C. Delgado

引用次数: 2

Specific aspects of ageing in Down's syndrome 唐氏综合症中衰老的具体方面

International Medical Review on Down Syndrome Pub Date : 2012-01-01 DOI: 10.1016/S2171-9748(12)70018-1

C. Farriols Danés

引用次数: 11

Clinical research and level of excellence in health care 临床研究和医疗保健的卓越水平

International Medical Review on Down Syndrome Pub Date : 2012-01-01 DOI: 10.1016/S2171-9748(12)70017-X

S. Videla

引用次数: 0

Nursing intervention protocol to help establish affective ties between the newborn infant with Down's syndrome and his/her family 帮助唐氏综合征新生儿与其家庭建立情感联系的护理干预方案

International Medical Review on Down Syndrome Pub Date : 2012-01-01 DOI: 10.1016/S2171-9748(12)70019-3

E. González Jiménez , M.J. Aguilar Cordero , J. Álvarez Ferre , C.A. Padilla López , M.C. González Jiménez

{"title":"Nursing intervention protocol to help establish affective ties between the newborn infant with Down's syndrome and his/her family","authors":"E. González Jiménez , M.J. Aguilar Cordero , J. Álvarez Ferre , C.A. Padilla López , M.C. González Jiménez","doi":"10.1016/S2171-9748(12)70019-3","DOIUrl":"10.1016/S2171-9748(12)70019-3","url":null,"abstract":"<div><p>The establishment of affective ties between mother and child is a universal phenomenon in all cultures. However, this process can be disrupted by contextual factors of the mother and her newborn child. The arrival of a baby is generally a joyful event in all families. Nevertheless, this situation can change when the newborn baby is not regarded as normal. This can sometimes cause a breach in the affective ties within the family, mainly between the parents and their child. Situations of this type are intensified when parents refuse to accept their Down's syndrome baby from the very beginning. Nursing professionals prepare strategies help in the emotional bonding from the time of diagnosis, and in the period immediately after childbirth. In this respect, nurses have a crucial role as information providers for the family. More specifically, they give parents emotional support and tell them about the importance of skin to skin contact, as well as the advantages of breastfeeding. The emotional process that the family is going through must be respected, especially the parents since they are responsible for the integration of the baby into the family unit. The objective of this research was to establish a standard nursing intervention protocol that helps to establish affective ties and bonding between the Down's syndrome baby and the family.</p></div>","PeriodicalId":100720,"journal":{"name":"International Medical Review on Down Syndrome","volume":"16 1","pages":"Pages 11-16"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2171-9748(12)70019-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90865223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Alopecia areata and Down's syndrome 斑秃和唐氏综合症

International Medical Review on Down Syndrome Pub Date : 2011-11-01 DOI: 10.1016/S2171-9748(11)70012-5

R. Alves , J. Ferrando

引用次数: 8

Postural analysis: prevention from physical therapy 体位分析:预防物理治疗

International Medical Review on Down Syndrome Pub Date : 2011-11-01 DOI: 10.1016/S2171-9748(11)70014-9

J.A. Caballero Blanco, A. Moreno Cabezas, M.V. Ortiz Garrido, C. Marín Padilla

{"title":"Postural analysis: prevention from physical therapy","authors":"J.A. Caballero Blanco, A. Moreno Cabezas, M.V. Ortiz Garrido, C. Marín Padilla","doi":"10.1016/S2171-9748(11)70014-9","DOIUrl":"10.1016/S2171-9748(11)70014-9","url":null,"abstract":"<div><h3>Introduction</h3><p>The physiotherapist is one of the first professionals who work with girls and boys with Down syndrome (DS) from birth. Due to the inherent characteristics of DS, should perform a preventative role from physiotherapy.</p></div><div><h3>Material and methods</h3><p>There has been studied a population of 14 persons with DS, 6 were girls and 8 were boys, with an average of age between 10 and 11 years. All of them have received as minimum 4 years of treatment physical therapy during his step along the early attention in Granadown. The postural analysis was observations and was realized in three planes of the space.</p></div><div><h3>Results</h3><p>10 (71.42%) had a lateral tilt of the head, 11 (78.57%) elevation of one of the two shoulders, 8 (57.14%) alterations of the pelvic girdle , 13 (92.85%) suffering from calcaneal valgus, 4 (28.57%) had chest abnormalities, 8 (57.14%) knee valgus, 2 (14.28%) had hallux valgus, 11 (78.57%) antepulsion head, 10 (71.42%) antepulsion right shoulder, 10 (71.42%) cervical kyphosis, 6 (42.85%) dorsal kyphosis, 3 (21.42%) back plane, 11 (78.57%) lumbar lordosis, 9 (64.28%) were hypotonic abdominal muscles and 8 (57.14%) shortening of the hamstrings.</p></div><div><h3>Conclusions</h3><p>We see the need to conduct longitudinal studies where it is evident from the long-term effectiveness of physiotherapy treatments in early attention. We should conduct periodic reviews in order to prevent alterations of the spine and to counsel families about the type of exercises and activities to be undertaken to prevent future children orthopedic deformities.</p></div>","PeriodicalId":100720,"journal":{"name":"International Medical Review on Down Syndrome","volume":"15 3","pages":"Pages 41-44"},"PeriodicalIF":0.0,"publicationDate":"2011-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2171-9748(11)70014-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78825838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4