Gastroenterología y Hepatología (English Edition)最新文献

{"title":"Intraductal oncocytic papillary neoplasm of the pancreas","authors":"Guillermo Castillo-López , Santiago González Vázquez , Beatriz Merchán Gómez , Maite Alonso-Sierra , César Prieto de Frías , Fernando Lapuente Sastre , Fernando Rotellar , Carolina Areán Cuns , Pilar López-Ferrer , José María Riesco López","doi":"10.1016/j.gastre.2025.502278","DOIUrl":"10.1016/j.gastre.2025.502278","url":null,"abstract":"","PeriodicalId":100569,"journal":{"name":"Gastroenterología y Hepatología (English Edition)","volume":"48 4","pages":"Article 502278"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periendoscopic management of antithrombotic drugs: Is cold snare polypectomy the answer?","authors":"Victor Argumánez ,&nbsp;Gema Plumé ,&nbsp;Marco Bustamante-Balén","doi":"10.1016/j.gastre.2025.502286","DOIUrl":"10.1016/j.gastre.2025.502286","url":null,"abstract":"<div><div>Patients undergoing colonoscopy are increasingly taking antithrombotic medication. These patients, who are generally older, also have a higher prevalence of colon polyps. Therefore, it is general practice to modify or discontinue antithrombotic treatment before colonoscopy, to reduce the risk of post-polypectomy bleeding (PPB). However, this modification increases the risk of thrombotic events. Currently, the main clinical guidelines recommend cold-snare resection for polyps smaller than 10<!--> <!-->mm because of its better safety profile, especially in reducing post-polypectomy bleeding. This reduced PPB rate could open the door to maintaining antithrombotic drugs in patients undergoing colonoscopy. This review aims to evaluate the evidence available so far that may support a modification of current guidelines on the management of antithrombotic drugs in the periendoscopic period.</div></div>","PeriodicalId":100569,"journal":{"name":"Gastroenterología y Hepatología (English Edition)","volume":"48 4","pages":"Article 502286"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tips and tricks for writing a manuscript to publish in a biomedical journal","authors":"Javier P. Gisbert ,&nbsp;María Chaparro","doi":"10.1016/j.gastre.2025.502237","DOIUrl":"10.1016/j.gastre.2025.502237","url":null,"abstract":"<div><div>Science barely exists until it is published. It is only then that the information surpasses the limits of the author and can be shared by the scientific community. Although scientific articles must follow a rigidly defined structure, there is still room to tell a fascinating story, one that clearly conveys the science and is, at the same time, enjoyable for the reader. To do this, we must use the attributes that characterize good scientific style, with simple, clear, precise, direct, rigorous, and consistent language. Authorship implies authenticity and authority, and considering a researcher as an author entails rights and responsibilities. Scientific writing is not easy, it requires patience and practice; learning to write well is a lifelong task. With the philosophy that most of the qualities required to proficiently write a scientific article depend on attitude, and can be learned and improved upon, in this manuscript we will share with the reader a series of recommendations (based on our own experiences, both positive and negative), which we consider important for writing and successfully publishing. We will focus on the so-called \"original\" articles (as opposed to review articles, although many of the recommendations presented are applicable to both). Our main purpose is to encourage researchers to take the necessary step and face the challenge of becoming authors of their own scientific articles and successfully publishing their research.</div></div><div>The abstract is like the “identity card” of our manuscript. It is the “showcase” where the most important results are presented. The abstract is an essential section of the manuscript as, after the title, it is probably the part that will attract the most readers. If the title is the gateway to the abstract, the abstract is the doorway to the article. It functions as the cover letter for the study, giving a structured outline that provides an overview of the content. An effective abstract can</div>","PeriodicalId":100569,"journal":{"name":"Gastroenterología y Hepatología (English Edition)","volume":"48 4","pages":"Article 502237"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the sensitivity and specificity of sigmoidoscopy in comparison to colonoscopy regarding the detection of intestinal inflammatory activity in the follow-up of patients with ulcerative colitis","authors":"Paula Calderón ,&nbsp;Paulina Núñez ,&nbsp;Karin Herrera ,&nbsp;Lilian Flores ,&nbsp;Andrea Córdova ,&nbsp;Francisca Carvajal ,&nbsp;Rodrigo Quera","doi":"10.1016/j.gastre.2025.502232","DOIUrl":"10.1016/j.gastre.2025.502232","url":null,"abstract":"<div><h3>Introduction</h3><div>Ulcerative colitis (UC) is a chronic disease characterized by periods of inflammatory activity and remission, which vary from the rectum to the proximal colon. Currently, mucosal healing is a long-term goal in the management of inflammatory bowel disease, with colonoscopy and sigmoidoscopy being the recommended tools for evaluation.</div></div><div><h3>Objective</h3><div>To assess the effectiveness of both examinations in determining the presence of inflammatory activity in the follow-up of patients with UC.</div></div><div><h3>Methods</h3><div>Retrospective observational study analyzing colonoscopies performed as part of the follow-up of UC patients between January 2021 and July 2023 by gastroenterologists from the Inflammatory Bowel Disease Program at the Clínica Universidad de los Andes. The study compared endoscopic and histological activity observed in the rectosigmoid region with that found in the rest of the colon. Sensitivity and specificity were determined using concordance and correlations tests.</div></div><div><h3>Results</h3><div>A very good concordance and correlation were observed regarding endoscopic findings, with a Kappa index of 0.97 and a Spearman coefficient of 0.97. The Positive Predictive Value (PPV) of sigmoidoscopy for endoscopic activity was 1, and the Negative Predictive Value (NPV) was 0.96. In relation to histological activity, the concordance had a Kappa index of 0.93 and a Spearman coefficient of 0.93, with a PPV of sigmoidoscopy for histological activity being 1 and an NPV of 0.91.</div></div><div><h3>Conclusion</h3><div>This cohort suggests that sigmoidoscopy is a cost-effective option for evaluating mucosal healing in UC patients in symptomatic and biomarker remission. However, complete colonoscopy should be considered in cases of discrepancies with the clinical picture or in colorectal cancer surveillance.</div></div>","PeriodicalId":100569,"journal":{"name":"Gastroenterología y Hepatología (English Edition)","volume":"48 3","pages":"Article 502232"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for advanced liver disease incorporating the use of transitional elastography in primary care","authors":"Mar Noguerol Álvarez ,&nbsp;M. Paz Valer López Fando ,&nbsp;Carolina Torrijos Bravo ,&nbsp;M. Carmen Gómez Ortiz ,&nbsp;Belén Piqueras Alcohol ,&nbsp;Antonio Guardiola Arévalo ,&nbsp;Gema De la Poza Gómez ,&nbsp;Zahara Pascual García ,&nbsp;Sandra Rey Rodríguez ,&nbsp;Raquel Iglesias Sigüenza ,&nbsp;Esther Ledesma Estévez ,&nbsp;Susana Parra Román ,&nbsp;María Gómez Suárez ,&nbsp;Angela Pérez San Juan ,&nbsp;Miriam Ruiz Romero ,&nbsp;Laura Martínez Vega ,&nbsp;Beatriz López Uriarte ,&nbsp;Francisco Góngora Maldonado ,&nbsp;Blanca Martín Porras ,&nbsp;Pilar Serrano Gismero ,&nbsp;Fernando Bermejo San José","doi":"10.1016/j.gastre.2025.502242","DOIUrl":"10.1016/j.gastre.2025.502242","url":null,"abstract":"<div><h3>Objectives</h3><div>To describe the proportion of patients with liver fibrosis in at-risk populations in primary care (PC). To know the agreement between FIB-4 and transitional elastography (TE), interobserver agreement between PC and hospital care (HC) in TE, and associated risk Factors (RF).</div></div><div><h3>Methods</h3><div>Observational, descriptive, cross-sectional study in ≥16 years of age with RF for chronic liver disease. Sex and age, RF (alteration of liver tests (LT), metabolic syndrome, diabetes, obesity, alcohol consumption, hepatic steatosis), and FIB-4, controlled attenuation parameter and TE in PC and in HC, were collected. According to a consensus algorithm, vibration-controlled TE was performed in PC in patients with FIB-4 ≥ 1,3, and those with measurement ≥ 8 kPa were referred to HC.</div></div><div><h3>Results</h3><div>326 patients were studied. 71% were not referred to HC, due to liver stiffness&lt;8 kPa. 83 of the 95 derivations did TE in HC. 45(54%) had TE ≥ 8, and 25(30%)≥12. The proportion of patients with stiffness≥8 kPa was 13,8%(45/326) and ≥12 kPa, 7,6%(25/326). The predictive values ​​of the FIB-4 were low. The interobserver correlation coefficient between TE in PC and HC was 0,433. Variables associated with TE ≥ 8 in PC: LT alteration, diabetes and steatosis. With TE≥12: LT alteration, diabetes and obesity. Predictor variables: LT alteration and obesity.</div></div><div><h3>Conclusions</h3><div>The study supports the sequential performance of serum indices and TE as a screening for fibrosis in the at-risk population in PC, which allows a reduction in the percentage of patients referred to AH, and a better stratification of risk patients.</div></div>","PeriodicalId":100569,"journal":{"name":"Gastroenterología y Hepatología (English Edition)","volume":"48 3","pages":"Article 502242"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncommon cause of upper gastrointestinal bleeding: Spontaneous large gastric intramural hematoma","authors":"Tiago Lima Capela ,&nbsp;Tiago Cúrdia Gonçalves ,&nbsp;Joana Magalhães ,&nbsp;José Cotter","doi":"10.1016/j.gastre.2025.502259","DOIUrl":"10.1016/j.gastre.2025.502259","url":null,"abstract":"","PeriodicalId":100569,"journal":{"name":"Gastroenterología y Hepatología (English Edition)","volume":"48 3","pages":"Article 502259"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An innovative steroid application for preventing esophageal stricture in patients undergoing circumferential endoscopic submucosal dissection","authors":"Yonghong Luo ,&nbsp;Tingfa Peng ,&nbsp;Bing Hu ,&nbsp;Liansong Ye","doi":"10.1016/j.gastre.2025.502234","DOIUrl":"10.1016/j.gastre.2025.502234","url":null,"abstract":"","PeriodicalId":100569,"journal":{"name":"Gastroenterología y Hepatología (English Edition)","volume":"48 3","pages":"Article 502234"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Position statement of the Spanish Society of Primary Care Physicians (SEMERGEN) and Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on the management of inflammatory bowel disease in Primary Care","authors":"Daniel Ginard ,&nbsp;Noelia Fontanillas ,&nbsp;Iria Bastón-Rey ,&nbsp;M. Elena Pejenaute ,&nbsp;Marta Piqueras ,&nbsp;Silvia Alcalde ,&nbsp;Pilar Nos ,&nbsp;Mercedes Ricote ,&nbsp;Lucía Expósito ,&nbsp;Míriam Mañosa ,&nbsp;Manuel Barreiro-de Acosta ,&nbsp;Francisco Rodríguez-Moranta ,&nbsp;Yamile Zabana ,&nbsp;José Polo ,&nbsp;Ana Gutiérrez ,&nbsp;on behalf of GETECCU and SEMERGEN","doi":"10.1016/j.gastre.2024.502255","DOIUrl":"10.1016/j.gastre.2024.502255","url":null,"abstract":"<div><div>Primary Care is the first point of contact for most patients after the onset of symptoms of inflammatory bowel disease (IBD). Establishing an initial diagnostic process based on compatible symptoms and agreed criteria and referral pathways, depending on the degree of suspicion and the patient's situation, can reduce diagnostic delays. Once the patient is referred to the Digestive specialist and the diagnosis of IBD is established, a treatment and follow-up plan is structured. The management of the patient must be shared with the participation of the family practitioners in the diagnosis and treatment of concomitant or intercurrent pathologies, the recognition of flare-ups or complications (of IBD or treatments), education tasks or adherence control.</div><div>With the purpose of developing a comprehensive guide on the management of IBD aimed at Primary Care doctors, we have developed this positioning document collaboratively between the Spanish Society of Primary Care Physicians (SEMERGEN) and the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU).</div></div>","PeriodicalId":100569,"journal":{"name":"Gastroenterología y Hepatología (English Edition)","volume":"48 3","pages":"Article 502255"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Venetoclax as a possible chemopreventive agent in adenomatous polyposis: A case report","authors":"Cautar El Maimouni ,&nbsp;Maria Daca-Alvarez ,&nbsp;Julio Delgado ,&nbsp;Maria Pellisé ,&nbsp;Francesc Balaguer","doi":"10.1016/j.gastre.2025.502239","DOIUrl":"10.1016/j.gastre.2025.502239","url":null,"abstract":"","PeriodicalId":100569,"journal":{"name":"Gastroenterología y Hepatología (English Edition)","volume":"48 3","pages":"Article 502239"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small bowel Crohn's disease: Proximal lesions linked to increased inflammation and biologic treatment needs","authors":"João Carlos Gonçalves ,&nbsp;Cátia Arieira ,&nbsp;Sofia Xavier ,&nbsp;Joana Magalhães ,&nbsp;Maria João Moreira ,&nbsp;Bruno Rosa ,&nbsp;José Cotter","doi":"10.1016/j.gastre.2025.502235","DOIUrl":"10.1016/j.gastre.2025.502235","url":null,"abstract":"<div><h3>Objective</h3><div>Crohn's disease (CD) is heterogeneous, and proximal involvement in the small bowel (SB) is associated with worse outcomes. Nonetheless, studies on the impact of duodenal and jejunal lesions in SB CD are limited. This study aimed to investigate the clinical characteristics and outcomes of individuals diagnosed with SB CD, comparing those with and without proximal inflammation.</div></div><div><h3>Methods</h3><div>A cohort of 53 treatment-naive SB CD patients that underwent Capsule Endoscopy at diagnosis were retrospectively selected. The inflammatory activity was quantified using the Lewis Score for each SB tertile.</div></div><div><h3>Results</h3><div>Thirty-seven (69.8%) patients displayed inflammatory activity in the first and/or second tertile together with third tertile involvement (Proximal<!--> <!-->+<!--> <!-->T3 group). Sixteen (30.2%) had inflammation in the third tertile only (T3 group). Individuals in the Proximal<!--> <!-->+<!--> <!-->T3 group had a higher risk for moderate-to-severe inflammation (OR 4.93, 95% CI: 1.3–18.3, <em>p</em> <!-->=<!--> <!-->0.013). A subgroup analysis for those with mild inflammatory activity showed that individuals in the Proximal<!--> <!-->+<!--> <!-->T3 group initiated biologic drugs more often (OR 11, 95% CI: 1.1–109.7, <em>p</em> <!-->=<!--> <!-->0.036).</div></div><div><h3>Conclusion</h3><div>Proximal SB lesions are associated with increased inflammatory activity, necessitating more frequent use of biologics in patients with mild disease. Early detection of proximal SB CD with Capsule Endoscopy may contribute to timely treatment.</div></div>","PeriodicalId":100569,"journal":{"name":"Gastroenterología y Hepatología (English Edition)","volume":"48 3","pages":"Article 502235"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}