Future Dental Journal最新文献

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Retention Loss of Locator Attachment System Different Retention Retention Loss of Locator Attachment System Different Retention Caps for Two Implant Retained Mandibular Overdenture 不同定位器附着体固位损失定位器附着体固位损失不同固位帽对两种种植固位下颌覆盖义齿的影响
Future Dental Journal Pub Date : 2021-12-01 DOI: 10.54623/fdj.7029
Medhat A. Abdelaziz, A. Fawzy, R. Ghaly, Hossam I. Nassar
{"title":"Retention Loss of Locator Attachment System Different Retention Retention Loss of Locator Attachment System Different Retention Caps for Two Implant Retained Mandibular Overdenture","authors":"Medhat A. Abdelaziz, A. Fawzy, R. Ghaly, Hossam I. Nassar","doi":"10.54623/fdj.7029","DOIUrl":"https://doi.org/10.54623/fdj.7029","url":null,"abstract":"Purpose. The objective of this invitro study was to evaluate gradual loss of retention at different time intervals between four different colour coded retentive caps of locator R-TX attachment system through 3000 cycles resembling 3years of attachment usage. Material and Methods. According to prosthetically driven implant placement, two implants were digitally planned and placed by 3D printed surgical stent in an epoxy model. Forty-eight mandibular complete dentures divided into four groups (12 dentures for each group) were constructed to compare Loss of retention between (12 pairs of locator R-TX each retention cap: zero retention, low retention, medium retention and regular retention), each was subjected to insertion and removal cycles resembling 3years of patient usage. Retention values at zero, one, two, three years were recorded using universal testing machine. Results: Locator R-TX medium &low retention showed no statistically significant retention values through three years while locator R-TX regular retention cap showed better retention values at zero, first, second year of use. Conclusion. Locator R-TX attachment systems low, medium, regular retention cap had no statistically significant different retention values at the end of third year of use while there were only statistically significant primary retention values. Clinical Implications. The importance of difference retention caps appears only in the start of over denture treatment until complete patient adaptation to over denture treatment","PeriodicalId":100562,"journal":{"name":"Future Dental Journal","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90749732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The Influence of Three Root Canal Irrigation Methods on PostThe Influence of Three Root Canal Irrigation Methods on PostOperative Pain “Randomized Clinical Trial” 三种根管冲洗方式对术后疼痛的影响三种根管冲洗方式对术后疼痛的影响“随机临床试验”
Future Dental Journal Pub Date : 2021-12-01 DOI: 10.54623/fdj.7021
Nouran ElAfify
{"title":"The Influence of Three Root Canal Irrigation Methods on PostThe Influence of Three Root Canal Irrigation Methods on PostOperative Pain “Randomized Clinical Trial”","authors":"Nouran ElAfify","doi":"10.54623/fdj.7021","DOIUrl":"https://doi.org/10.54623/fdj.7021","url":null,"abstract":"Endodontics Aim: This clinical study was designated to evaluate the influence of three root canal irrigation activation methods on postoperative pain using the Visual Analogue Scale VAS. Material and Methods: 78 patients having symptomatic irreversible pulpitis in mandibular first molar with no periapical involvement. ProTaper Next rotary files were used for root canal preparation, the cases were then divided randomly into three equal groups based on the final irrigation agitation technique, with each group having 26 cases. (n=26 ). Group A: received irrigation with 2.6% sodium hypochlorite with NaviTip (31- gauge 27 mm) with double side port irrigator tip (SVN) without any agitation; Group B: received irrigation with 2.6% sodium hypochlorite with final mechanical agitation of irrigation with ultrasonic device activation (Endo ultra) (PUI) Group C: received irrigation with 2.6% sodium hypochlorite with final mechanical agitation of irrigation with sonic device activation (EDDY). Using a Visual Analogue Scale (VAS), postoperative pain was evaluated at intervals of 6,12,24,72 hours and 7 days. Results: Overall results of study showed ,At the first (6,12,24 hours) there was a significant difference between the groups in pain incidence and intensity where group A showed more pain scores than group B and group C. At (48, 72 hours and 7 days) there were no significant difference between the groups where pain scores declined among the groups till it reaches nearly score (0) at 7 day. Conclusion: group A (SVN) showed highest postoperative pain in the first 24 hours in comparison with the other groups, where the pain level decreased gradually in all groups after 24 hours.","PeriodicalId":100562,"journal":{"name":"Future Dental Journal","volume":"160 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76699129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Influence of Etching Methods on the Shear Bond Strength of a Influence of Etching Methods on the Shear Bond Strength of a Universal Adhesive System to Sound and Artificial Caries-Affected Universal Adhesive System to Sound and Artificial Caries-Affected Dentin 蚀刻方法对剪切结合强度的影响蚀刻方法对通用粘接系统对声音和人工龋齿影响的牙本质剪切结合强度的影响
Future Dental Journal Pub Date : 2021-12-01 DOI: 10.54623/fdj.70210
Omnia M. Sami, E. Naguib, R. Afifi, shaima nagi
{"title":"Influence of Etching Methods on the Shear Bond Strength of a Influence of Etching Methods on the Shear Bond Strength of a Universal Adhesive System to Sound and Artificial Caries-Affected Universal Adhesive System to Sound and Artificial Caries-Affected Dentin","authors":"Omnia M. Sami, E. Naguib, R. Afifi, shaima nagi","doi":"10.54623/fdj.70210","DOIUrl":"https://doi.org/10.54623/fdj.70210","url":null,"abstract":"Purpose:This study tested the bond strength of a universal adhesive system to both caries-affected (CAD) and sound dentin after using different etching techniques. Methods: Forty premolars were wet grinded to expose flat occlusal midcoronal dentin. Specimens were equally divided according to the substrate into sound and (CAD) specimens which were exposed to pH- cycling for 14 days. Single Bond™ universal adhesive was used to bond each dentin substrate either after no etching or etching of dentin, after which, resin composite was used for build-up. These specimens were then tested for shear bond strength (SBS). The results were then analyzed by two-ways ANOVA. Results: Single Bond™ universal bonded to sound dentin had statistically significantly higher SBS mean values compared to CAD. Single Bond™ applied after separate etching step of dentin showed a statistically higher SBS compared to self-etching method when bonded to sound dentin. Conclusion: Separate etching improved bonding to sound dentin and did not influence the bond strength of tested universal adhesive to CAD.","PeriodicalId":100562,"journal":{"name":"Future Dental Journal","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81856183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of Diffusion Weighted Magnetic Resonance Imaging in Accuracy of Diffusion Weighted Magnetic Resonance Imaging in Differentiation between Malignant and Non-malignant Differentiation between Malignant and Non-malignant Maxillofacial Lesions Maxillofacial Lesions 弥散加权磁共振成像在颌面部恶性与非恶性鉴别中的准确性弥散加权磁共振成像在颌面部恶性病变鉴别中的准确性
Future Dental Journal Pub Date : 2021-06-01 DOI: 10.54623/fdj.7015
R. Ashraf, Mostafa S. Ashmawy, Mena E. Y. Ekladious, Gihan Omar, mona aboelfetouh
{"title":"Accuracy of Diffusion Weighted Magnetic Resonance Imaging in Accuracy of Diffusion Weighted Magnetic Resonance Imaging in Differentiation between Malignant and Non-malignant Differentiation between Malignant and Non-malignant Maxillofacial Lesions Maxillofacial Lesions","authors":"R. Ashraf, Mostafa S. Ashmawy, Mena E. Y. Ekladious, Gihan Omar, mona aboelfetouh","doi":"10.54623/fdj.7015","DOIUrl":"https://doi.org/10.54623/fdj.7015","url":null,"abstract":"Objectives: to evaluate the signal characteristics of Diffusion Weighted Magnetic Resonance Imaging (DWMRI) of maxillofacial intraosseous lesions and their corresponding apparent diffusion coefficient (ADC) values and assess their ability to differentiate between malignant and non-malignant lesions. Methods: This study included 17 patients (10 males and 7 females) selected from the outpatients’ clinic of Oral Surgery Department, Faculty of Dentistry, Ain-shams University. They were examined by MRI machine; Philips 1.5 Tesla Achieva, Netherlands using DWMRI, T1 and T2 sequences and ADC values were measured. Results: There was a statistically significant difference between T1 signal distributions among patients with benign and malignant lesions (P-value = 0.027, Effect size = 0.685) benign lesions showed higher prevalence of low signal while malignant lesions showed higher prevalence of intermediate signal. There was a statistically significant difference between T2 signal distributions among patients with benign and malignant lesions (P-value = 0.029, Effect size = 0.609). Benign lesions showed higher prevalence of high signal while malignant lesions showed higher prevalence of intermediate signal. ROC curve analysis showed a cut-off value of (≤ 1 ´10-3 mm2) with diagnostic accuracy of 94.1%, a sensitivity of 100% and specificity of 91.7% indicating that ADC values less than or equal to 1 ´10-3 mm2 indicate malignant lesion and values greater than 1 ´10-3 mm2 indicate benign lesion (P-value <0.001, Effect size = 3.25). Conclusion: DWMRI is highly accurate in the differentiation between benign and malignant intraosseous lesions of the ja","PeriodicalId":100562,"journal":{"name":"Future Dental Journal","volume":"198 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82808043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three-Dimensional Maxillary Alveolar Ridge Augmentation Using Three-Dimensional Maxillary Alveolar Ridge Augmentation Using Modified Cortical Shell Technique and Composite Bone Graft 改良皮质壳技术及复合骨移植的三维上颌牙槽嵴增强术
Future Dental Journal Pub Date : 2021-06-01 DOI: 10.54623/fdj.7012
M. Azab, M. Diaa, A. Ghanem, M. Badr
{"title":"Three-Dimensional Maxillary Alveolar Ridge Augmentation Using Three-Dimensional Maxillary Alveolar Ridge Augmentation Using Modified Cortical Shell Technique and Composite Bone Graft","authors":"M. Azab, M. Diaa, A. Ghanem, M. Badr","doi":"10.54623/fdj.7012","DOIUrl":"https://doi.org/10.54623/fdj.7012","url":null,"abstract":"Objective: The present study was performed to assess the 3D alveolar ridge augmentation using the cortical shell from retromolar region and composite bone particulate regarding the width of the residual alveolar ridge. Methods: Thirteen patients with age range 21-40 years old having atrophic anterior maxillary ridge ≤3mm horizontally were included in the study. All patients were subjected to ridge augmentation using composite bone graft and retromolar cortical shell that was fixed in place by two micro-screws. The alveolar ridges were assessed and compared by cone beam computed tomography (CBCT) in the pre-operative, immediate and 4 months post-operative phases by taking linear measurements at the same points after making fusion. The measurements were taken at the crest of the ridge, midway and more apically. The CBCT images were evaluated for the actual gain in width of the alveolar ridge. Statistical analysis was performed to compare CBCT and clinical findings. Results: At the crest of the ridge, midway and more apically the results showed a statistically significant difference between pre-operative and immediate post-operative results (P0.05). The mean increases in crestal bone width, midway and apically at 4 months postoperatively were 3.66mm, 4.01mm and 3.5mm respectively. Conclusion: 3D reconstruction of anterior maxillae with autogenous retromolar cortical shell is a reliable technique with stable outcomes. Two micro- screws Stabilization provides stability and minimal graft resorption. Moreover, the technique allows for implant placement 4 months post-operatively without further re-grafting.","PeriodicalId":100562,"journal":{"name":"Future Dental Journal","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79664150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Treatment of Implant Labial Soft Tissue Dehiscence with Guided Treatment of Implant Labial Soft Tissue Dehiscence with Guided Bone Regeneration vs Subepithelial Connective Tissue Graft. A Bone Regeneration vs Subepithelial Connective Tissue Graft. A Randomized Clinical Trial 引导下骨再生与上皮下结缔组织移植治疗种植体唇软组织裂的比较。骨再生与上皮下结缔组织移植。一项随机临床试验
Future Dental Journal Pub Date : 2021-06-01 DOI: 10.54623/fdj.7013
Mahmoud M Elrayes, wael esmael, MohamedS.E Atef, L. Abdelaziz.
{"title":"Treatment of Implant Labial Soft Tissue Dehiscence with Guided Treatment of Implant Labial Soft Tissue Dehiscence with Guided Bone Regeneration vs Subepithelial Connective Tissue Graft. A Bone Regeneration vs Subepithelial Connective Tissue Graft. A Randomized Clinical Trial","authors":"Mahmoud M Elrayes, wael esmael, MohamedS.E Atef, L. Abdelaziz.","doi":"10.54623/fdj.7013","DOIUrl":"https://doi.org/10.54623/fdj.7013","url":null,"abstract":"Objective: Background: Implant soft tissue dehiscence is a frequently reported esthetic complication, that more often than not affects the functional integrity of the dental implant with eventual loss of osteointegration. Many treatment modalities with different success rates have been proposed aiming to solve this complication or prolong the survival of the dental implant, of which are guided bone regeneration and soft tissue regeneration around the affected implants. Patients and Methods: This prospective study was carried in the hospital of Future University. 11 Patients (1 Male – 10 Females) with 20 Maxillary implant sites demonstrating soft tissue dehiscence were randomly allocated to either a guided bone regeneration (GBR) group (Control) in which patients received a mixture of autogenous and xenogeneic bone graft substitute covered by a native collagen membrane fixated with titanium tacks over the affected implants or a connective tissue graft and coronal flap advancement (CTG + CAF) group (Intervention) in which patients received a de-epithelialized connective tissue graft harvest from the anterio-lateral hard palate combined with a coronally advanced flap. Recession levels were measured at baseline and at 1,3 and 6 months post operatively, while probing depths and bleeding indices were measured at baseline and 6 months post operatively and patient satisfaction levels were recorded through a visual analogue scale (VAS) questionnaire 6 months post operatively after completion of the follow up period. Results: Out of the 11 patients (1 Male – 10 Females) enrolled in this study, no major post-operative complications were encountered, the most common complication was post-operative swelling and edema that usually peaked 48 hours after surgery, which was more evident in the GBR group. Soft tissue recession levels measured from implant platform to gingival margin was significantly higher at baseline in GBR group compared to CTG+CAF group (P=0.042). While there was no significant difference in soft tissue levels between both groups at 1 month (P=0.362), 3 months (P=0.240) and 6 months (P=0.097). There was no statistically significant difference in VAS mean values between GBR and CTG+CAF groups (P=0.510). Conclusion: Based on the results of our study, we concluded that both treatment modalities provided satisfactory and stable results with major improvements in all clinical outcomes after 6 months compared to baseline measurements, however, GBR provided slightly superior clinical outcomes, compared to CTG + CAF","PeriodicalId":100562,"journal":{"name":"Future Dental Journal","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75436535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Hydrothermal Aging on Translucency of Different Types of Zirconia and Lithium Disilicate at Variable Thicknesses 水热老化对不同厚度氧化锆和二硅酸锂半透明性的影响
Future Dental Journal Pub Date : 2021-06-01 DOI: 10.54623/fdj.70112
T. Morsi, Mennatallah Wahba
{"title":"Effect of Hydrothermal Aging on Translucency of Different Types of Zirconia and Lithium Disilicate at Variable Thicknesses","authors":"T. Morsi, Mennatallah Wahba","doi":"10.54623/fdj.70112","DOIUrl":"https://doi.org/10.54623/fdj.70112","url":null,"abstract":"Objective: The aim of this in vitro study was to investigate the effect of hydrothermal aging on translucency parameter (TP) of different zirconia ceramics in different thicknesses. Material and Methods: This is an in-vitro study in which translucency of six pre-sintered and pre-shaded zirconia materials (In Coris ZI, In Coris TZI, Bruxzir Solid, KATANA HT, KATANA ST, and KATANA UT) was compared to a low-translucency, lithium disilicate glass-ceramic material (IPS e.max CAD LT, Ivoclar Vivadent). The ceramic blocks were cut in the form of plates of dimensions (14x10 mm) and of different thicknesses (0.5, 0.7,1 mm). Thirty specimens of each ceramic material were classified into three groups according to thickness (n=10) such that the total number of specimens is 210. After all zirconia specimens were sintered and lithium disilicate samples were crystallized, TP was determined using dental spectrophotometer VITA Easyshade Compact. Same procedure of translucency measurement was done again after samples were subjected to accelerated autoclave aging. Results: Paired-Samples T- Test showed that aging caused significant reduction in TP in all materials in all thicknesses. Moreover, there was statistical significant difference (P < 0.05) between different ceramic materials where e.max CAD LT showed the highest (TP) and In Coris ZI showed the lowest TP in all thickness groups. Conclusions: TP was both thickness and material dependent. TP was also affected by LTD.","PeriodicalId":100562,"journal":{"name":"Future Dental Journal","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80447477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Interleukin-17 (IL-17) Concentration in Saliva of Patients with The Interleukin-17 (IL-17) Concentration in Saliva of Patients with Oral Lichen Planus 口腔扁平苔藓患者唾液中白细胞介素-17 (IL-17)的含量
Future Dental Journal Pub Date : 2021-06-01 DOI: 10.54623/fdj.7019
mai elgendy, Radwa R Hussein, A. Hassan, O. Shaker
{"title":"The Interleukin-17 (IL-17) Concentration in Saliva of Patients with The Interleukin-17 (IL-17) Concentration in Saliva of Patients with Oral Lichen Planus","authors":"mai elgendy, Radwa R Hussein, A. Hassan, O. Shaker","doi":"10.54623/fdj.7019","DOIUrl":"https://doi.org/10.54623/fdj.7019","url":null,"abstract":"Background: The aim of the present study was to measure the clinical and pain score in these patients and to measure the level of IL-17 in saliva of patients having different forms of Oral lichen planus lesions (OLP). Subjects and methods: According to sample size calculation, the present study was done on a total of 40 subjects divided into 3 groups Group (I) Twenty patients having erosive/atrophic OLP. Group (II) Ten patients having reticular OLP and Group (III) Ten healthy control patients. Salivary samples were collected from the subjects of the three groups to evaluate the levels of IL-17 using enzyme-linked immunosorbent assay (ELISA). Results: The values of the clinical and pain score were statistically significantly higher in the erosive/atrophic group than both the reticular and healthy control subjects. The levels of IL-17 in saliva of patients with erosive/atrophic OLP were statistically significantly higher than in patients with the reticular OLP and healthy control subjects, and there was a high statistically significant difference between the reticular group and the healthy control subjects p<0.001. Conclusions: According to the results, the salivary levels of IL-17 are higher in the erosive/ atrophic type of OLP than the reticular type and both are higher than the healthy control subjects. This suggested that IL- 17 has a great role in the immunepathogenesis of OLP and may be of diagnostic value for the severity of the condition of the erosive/atrophic OLP.","PeriodicalId":100562,"journal":{"name":"Future Dental Journal","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86824356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative Pain After Different Root Canal Irrigant Activation Postoperative Pain After Different Root Canal Irrigant Activation Methods; (Randomized Clinical Trial) Methods; (Randomized Clinical Trial) 不同根管冲洗激活方式对术后疼痛的影响(随机临床试验)方法;(随机临床试验)
Future Dental Journal Pub Date : 2021-06-01 DOI: 10.54623/fdj.7011
Yasmine Abou khalaf, A. Hashem, Wael H. Kamel, M. Badr
{"title":"Postoperative Pain After Different Root Canal Irrigant Activation Postoperative Pain After Different Root Canal Irrigant Activation Methods; (Randomized Clinical Trial) Methods; (Randomized Clinical Trial)","authors":"Yasmine Abou khalaf, A. Hashem, Wael H. Kamel, M. Badr","doi":"10.54623/fdj.7011","DOIUrl":"https://doi.org/10.54623/fdj.7011","url":null,"abstract":"Objective: This study was designated to evaluate postoperative pain in irreversible symptomatic teeth after different irrigation activation methods using visual analogue scale. Materials and Methods:78 Patients having symptomatic irreversible pulpitis in mandibular first molar (vital pulp) with no periapical involvement were involved in the study. Cases were classified into three groups according to the the final irrigation agitation method used, twenty-six patients each group (n=26). Group A: Root canals were irrigated using NaOCl2* 2.6% with NaviTip (31-gauge 27mm) with double side port irrigator tip (SVN). Group B: Root canals were irrigated using 2.6% NaOCl with manual dynamic agitation using master cone for 60 seconds. Group C: Root canals were irrigated using 2.6% NaOCl with mechanical agitation using ultrasonic device ultra-x for 60 seconds. Postoperative pain was evaluated after 6,12,24, 48, and 72 hours and 1 week. Data were explored for normality using Kolmogorov-Smirnov and Shapiro-Wilk tests and showed parametric (normal) distribution. Statistical analysis was performed with IBM® SPSS® Statistics Version 20 for Windows. Results: Severity of postoperative pain was more intense at 6- 12and 24-hour time intervals in group 2 patients than those patients in groups 1and 3 (P < .05). There was no significant difference among the groups at the other time intervals (P > .05). Severity of postoperative pain in all groups decreased over time. Conclusion: After endodontic therapy in lower molars with acute pulpitis manual dynamic agitation caused greater postoperative pain in comparison with the other methods in the first 24 hours.","PeriodicalId":100562,"journal":{"name":"Future Dental Journal","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81245151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The effect of Doxorubicin and Thioridazine on squamous The effect of Doxorubicin and Thioridazine on squamous carcinoma cell line 阿霉素和噻嗪对鳞状细胞的影响阿霉素和噻嗪对鳞状细胞的影响
Future Dental Journal Pub Date : 2021-06-01 DOI: 10.54623/fdj.7016
bassant mostafa, E. Helmy, H. Elkammar, nermine afifi
{"title":"The effect of Doxorubicin and Thioridazine on squamous The effect of Doxorubicin and Thioridazine on squamous carcinoma cell line","authors":"bassant mostafa, E. Helmy, H. Elkammar, nermine afifi","doi":"10.54623/fdj.7016","DOIUrl":"https://doi.org/10.54623/fdj.7016","url":null,"abstract":"Background: Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers occupying the sixth position worldwide. PI3k/Akt signaling pathway plays a significant role in regulating diverse cellular functions. This includes cell growth, proliferation and survival via inhibition of apoptosis, transcription and protein synthesis. One of the most acknowledged and approved chemotherapeutic agents is Doxorubicin (DOX) which is a non- selective class I anthracycline. In spite of DOX being one of the most acknowledged chemotherapeutic agents, its use has been limited by its toxic side effects and the development of chemoresistance. Nowadays, Thioridazine (TZ) which is a newly repurposed drug that was originally used in the treatment of psychosis, schizophrenia and anxiety, has been tested in the treatment of breast, ovarian, gastric cancers and leukemias. Methods: MTT was employed to assess the effect of TZ and DOX on the separately and in combination, with different doses and durations on the HEp2 cell line. The efficacy of both drugs was evaluated separately and in combination with different doses and durations on inhibition of cell migration on the HEp2 cell line. Results: The results of this study revealed that the highest viability was with the control group followed by the TZ group I (low dose), compared to the other groups. While it showed that the lowest mean viability was with the combination group VI (high dose) compared to other groups. Regarding the mean values of cell migration, the lowest mean value was noted in the combination group III, and the highest mean values was noted in the control group, followed by the DOX group I. Conclusion: From the results of this study it can be concluded that combination group of DOX an d TZ is a promising treatment for HEp2 cell line.","PeriodicalId":100562,"journal":{"name":"Future Dental Journal","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76180864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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