Fooyin Journal of Health Sciences最新文献

Great Burdock Extract on Rabbit Corpus Cavernosum 大牛蒡提取物对兔海绵体的作用

Fooyin Journal of Health Sciences Pub Date : 2010-08-01 DOI: 10.1016/S1877-8607(11)60006-4

I-Jen Tseng , Hsin-Hung Tsai , Li-Chen Yen , Rong-Jyh Lin , Tong-Rong Tsai , Chan-Hang Wu , Shin-Chiang Lee , Yi-Ching Lo , Shiu-Ru Lin

{"title":"Great Burdock Extract on Rabbit Corpus Cavernosum","authors":"I-Jen Tseng , Hsin-Hung Tsai , Li-Chen Yen , Rong-Jyh Lin , Tong-Rong Tsai , Chan-Hang Wu , Shin-Chiang Lee , Yi-Ching Lo , Shiu-Ru Lin","doi":"10.1016/S1877-8607(11)60006-4","DOIUrl":"10.1016/S1877-8607(11)60006-4","url":null,"abstract":"<div>Great burdock (Arctium lappa) is an edible vegetable that is also used as herbal medicines in many countries. Traditionally, burdock is used to slow aging, cure male impotence and in beauty care. However, the relevant mechanisms and scientific proof of its actions have not yet been elucidated. The expansion of the corpora cavernosum smooth muscle cells of the penis is the main regulating factor of erection, and the nitric oxide-soluble guanylyl cyclase-cyclic guanine monophosphate (NO-sGC-cGMP) pathway plays an important role in maintaining expansion of the corpora cavernosum. The current study aims are to investigate the effects of burdock extract on a rabbit's corpora cavernosum. The effects of burdock on the protein expression in the cavernosum tissues and smooth muscle cells were investigated, and the changes in cGMP level were determined via enzyme-linked immunosorbent assay kit analysis. Our results showed that burdock extract increased the expression of neuronal nitric oxide synthase, cGMP-dependent kinase, sGCα1 and sGCβ1 in the smooth muscle cells and tissues of the corpora cavernosum, while the expression of phosphodiesterase-5 was inhibited. Additionally, cGMP levels become elevated in the smooth muscles after treatment with burdock extract. In summary, our data suggest that burdock can facilitate in the relaxation of the corpora cavernosum; however, the benefits of burdock in treating erectile dysfunction remain to be resolved.</div>","PeriodicalId":100548,"journal":{"name":"Fooyin Journal of Health Sciences","volume":"2 3","pages":"Pages 98-104"},"PeriodicalIF":0.0,"publicationDate":"2010-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1877-8607(11)60006-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75420113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular Characterization of Cryptosporidium spp. in HIV-infected Persons in Benin City, Edo State, Nigeria 尼日利亚埃多州贝宁市hiv感染者隐孢子虫的分子特征

Fooyin Journal of Health Sciences Pub Date : 2010-08-01 DOI: 10.1016/S1877-8607(11)60003-9

Frederick Olusegun Akinbo , Christopher Ehis Okaka , Richard Omoregie , Theressa Dearen , Eucaris Torres Leon , Lihua Xiao

{"title":"Molecular Characterization of Cryptosporidium spp. in HIV-infected Persons in Benin City, Edo State, Nigeria","authors":"Frederick Olusegun Akinbo , Christopher Ehis Okaka , Richard Omoregie , Theressa Dearen , Eucaris Torres Leon , Lihua Xiao","doi":"10.1016/S1877-8607(11)60003-9","DOIUrl":"10.1016/S1877-8607(11)60003-9","url":null,"abstract":"<div>The use of molecular tools in epidemiological investigations has provided new insights into the transmission of cryptosporidiosis in humans and animals. This study aimed to characterize the transmission of cryptosporidiosis in human immunodeficiency virus (HIV)-infected patients. Stool specimens were collected from 500 HIV-infected patients as part of the routine patient care. Cryptosporidium species in stool specimens were detected and differentiated using a small subunit rRNA-based polymerase chain reaction-restriction fragment length polymorphism technique. C. hominis and C. parvum were found and subtyped by DNA sequence analysis of the 60 kDa glycoprotein (gp60) gene. Cryptosporidium species were detected in 36 HIV patients and none were found among non-HIV patients. A CD4+ count < 200 cells/μL was a significant risk factor for acquiring cryptosporidiosis (odds ratio = 21.214; 95% confidence interval = 9.917, 45.381; p < 0.0001). Cryptosporidium infection was also associated with weight loss and diarrhea. Other risk factors included animal contact, and using stream/river or well water as drinking water. Genotyping of the Cryptosporidium species identified the presence of C. hominis (47.2%), C. parvum (44.4%), C. felis (5.6%) and C. canis (2.8%). The C. hominis specimens subtyped belonged to the Ia, Ib and Ie subtype families, whereas those of C. parvum belonged to the IIc and two new subtype families. Anthroponotic transmission appears to be important in cryptosporidiosis epidemiology in HIV-infected persons in Nigeria despite the high frequency of C. parvum infection and the identification of animal contact as a risk factor.</div>","PeriodicalId":100548,"journal":{"name":"Fooyin Journal of Health Sciences","volume":"2 3","pages":"Pages 85-89"},"PeriodicalIF":0.0,"publicationDate":"2010-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1877-8607(11)60003-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73681546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Urinary Tract Infections Among the Elderly in Benin City, Nigeria 尼日利亚贝宁市老年人尿路感染的研究

Fooyin Journal of Health Sciences Pub Date : 2010-08-01 DOI: 10.1016/S1877-8607(11)60004-0

Richard Omoregie , Isaac Ohiorenuan Igbarumah , Christopher Aye Egbe , Helen Ogefere

{"title":"Urinary Tract Infections Among the Elderly in Benin City, Nigeria","authors":"Richard Omoregie , Isaac Ohiorenuan Igbarumah , Christopher Aye Egbe , Helen Ogefere","doi":"10.1016/S1877-8607(11)60004-0","DOIUrl":"10.1016/S1877-8607(11)60004-0","url":null,"abstract":"<div>The elderly have an increased risk of developing urinary tract infection (UTI). This study aimed to determine the prevalence of UTI among elderly (≥ 60 years) patients in Benin City, Nigeria. Clean-catch midstream urine was collected from 943 (362 males and 581 females) elderly patients with signs and symptoms of UTI. Significant microbial isolates were identified in the urine specimens and an antimicrobial susceptibility test was performed on bacteria isolates using standard techniques. Male sex was a significant risk factor for acquiring UTI in the elderly (odds ratio = 6.584; 95% confidence interval = 4.081, 10.62; p < 0.0001). There was an inverse relationship between age and prevalence of UTI, as the prevalence of UTI significantly declined with increasing age (p = 0.023). Escherichia coli was the most common uropathogen (36.79%) in both sexes of elderly patients. Bacterial isolates were poorly susceptible to antibacterial agents used. An overall prevalence of 11.03% of UTI was observed among the elderly. Male sex showed an approximately 4-11-fold increased risk of acquiring UTI. The prevalence of UTI among the elderly decreases with increasing age. Rational use of antibiotics is advocated to stem the tide of high antibacterial resistance.</div>","PeriodicalId":100548,"journal":{"name":"Fooyin Journal of Health Sciences","volume":"2 3","pages":"Pages 90-93"},"PeriodicalIF":0.0,"publicationDate":"2010-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1877-8607(11)60004-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90743900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

A Successful Intervention to Reduce Cigarillo Use Among Baltimore Youth 巴尔的摩青少年减少小雪茄使用的成功干预

Fooyin Journal of Health Sciences Pub Date : 2010-08-01 DOI: 10.1016/S1877-8607(11)60002-7

Fei-Kai Syu , Ming-Yii Huang , Jon-Jong Huang

引用次数: 6

Effects of Chronic Administration of Efavirenz on the Inferior Colliculus of Adult Wistar Rats 长期服用依非韦伦对成年Wistar大鼠下丘的影响

Fooyin Journal of Health Sciences Pub Date : 2010-08-01 DOI: 10.1016/S1877-8607(11)60007-6

Josiah Obaghwarhievwo Adjene , Patrick Sunday Igbigbi

引用次数: 6

Ethical Issues of Disaster Medicine: Taiwan's Experience of Typhoon Morakot 灾害医学的伦理问题:台湾在莫拉克台风中的经验

Fooyin Journal of Health Sciences Pub Date : 2010-08-01 DOI: 10.1016/S1877-8607(11)60005-2

Joh-Jong Huang , Vincent Shieh , Ming-Yii Huang , Huei-Wen Angela Lo

引用次数: 1

Severe Hemolytic Anemia due to Active Pulmonary Tuberculosis 活动性肺结核所致严重溶血性贫血

Fooyin Journal of Health Sciences Pub Date : 2010-08-01 DOI: 10.1016/S1877-8607(11)60009-X

Hsueh-Chen Chen , la-Tang Huang , Hong-Chung Wang

引用次数: 4

Tibial Hemangiopericytoma Diagnosed by Nuclear Medicine Techniques 胫骨血管外皮细胞瘤的核医学诊断

Fooyin Journal of Health Sciences Pub Date : 2010-08-01 DOI: 10.1016/S1877-8607(11)60008-8

Padma Sundaram, Shanmuga Sundaram Palaniswamy, Shamly George, Vijay Harish, Jay Kumar Rai

引用次数: 0

Liberated Anomie in Generation Next: Hyperindividualism, Extreme Consumerism, and Social Isolationism 新一代的自由失范:超个人主义、极端消费主义和社会孤立主义

Fooyin Journal of Health Sciences Pub Date : 2010-05-01 DOI: 10.1016/S1877-8607(10)60013-6

Joh-Jong Huang , Ming-Yii Huang , Fei-Kai Syu

{"title":"Liberated Anomie in Generation Next: Hyperindividualism, Extreme Consumerism, and Social Isolationism","authors":"Joh-Jong Huang , Ming-Yii Huang , Fei-Kai Syu","doi":"10.1016/S1877-8607(10)60013-6","DOIUrl":"10.1016/S1877-8607(10)60013-6","url":null,"abstract":"<div>Liberated anomie is a defining feature of Generation Next, allowing young adults to hold wide latitudes of acceptance for risk behaviors by disengaging from others and from the negative impact their actions may have on society. This cohort's experiences with hyperindividualism, extreme consumerism, and social isolationism have created hypertolerance for deviant behaviors. The impact of online communications, a child-centric upbringing, and the historical and cultural forces that shaped Generation Next have created unique challenges for developing health messages for young adults. Clarification of cohort-defining values, however, provides a starting point for framing health messages. Key features of successful public health messages will reduce normative fallacy related to risk behaviors among young adults, appeal to the individual and provide opportunities to consume products or services related to the message. Most importantly, public health must be part of the creation of new rituals, both online and offline, so that social consciousness and social control can be developed in concert with the core values of Generation Next.</div>","PeriodicalId":100548,"journal":{"name":"Fooyin Journal of Health Sciences","volume":"2 2","pages":"Pages 41-47"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1877-8607(10)60013-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81080403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Effect of Chronic Consumption of Nutmeg on the Stomach of Adult Wistar Rats 长期食用肉豆蔻对成年Wistar大鼠胃的影响

Fooyin Journal of Health Sciences Pub Date : 2010-05-01 DOI: 10.1016/S1877-8607(10)60017-3

Josiah Obaghwarhievwo Adjene , Patrick Sunday Igbigbi

{"title":"Effect of Chronic Consumption of Nutmeg on the Stomach of Adult Wistar Rats","authors":"Josiah Obaghwarhievwo Adjene , Patrick Sunday Igbigbi","doi":"10.1016/S1877-8607(10)60017-3","DOIUrl":"10.1016/S1877-8607(10)60017-3","url":null,"abstract":"<div>Nutmeg is commonly used as a spice in various dishes; it is a component of teas and soft drinks, and can also be mixed in milk and alcohol. In this study, we investigated the effect of chronic consumption of nutmeg on the stomach of adult Wistar rats. Rats of both sexes (n = 24), with an average weight of 200 g, were randomly assigned into two treatment groups (A and B, n = 8 for each group) and one control group (C, n = 8). The rats in the treatment groups received 1 g of nutmeg in group A and 2 g of nutmeg in group B. The nutmeg was thoroughly mixed with feed and given daily for 32 days. Group C received an equal amount of feed daily without nutmeg for 32 days. The rats had free access to water. On day 33 of the experiment, the rats were sacrificed by cervical dislocation. The stomachs were carefully dissected out and immediately fixed in 10% formal saline for histological study. Hematoxylin and eosin staining showed that rats in groups A and B showed varying degrees of distortion in the epithelial cells of the stomach. Obvious signs of proliferation, hyperplasia, and atrophic changes in the treated stomach sections were more marked in group B than in the other groups. These findings indicate that nutmeg may have some deleterious effects on the microanatomy of the stomach of adult Wistar rats.</div>","PeriodicalId":100548,"journal":{"name":"Fooyin Journal of Health Sciences","volume":"2 2","pages":"Pages 62-65"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1877-8607(10)60017-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72911834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6