{"title":"Methicillin-resistant Staphylococcus aureus: acquisition and risk of death in patients in the intensive care unit","authors":"Maaike M. S. Ibelings, Hajo A. Bruining","doi":"10.1080/110241598750004210","DOIUrl":"10.1080/110241598750004210","url":null,"abstract":"OBJECTIVE\u0000To evaluate the risk of patients in intensive care units (ICU) of becoming infected with methicillin-resistant Staphylococcus aureus (MRSA) and to assess the mortality during a six week follow-up period, compared with patients who developed methicillin-sensitive S. aureus (MSSA) infection.\u0000\u0000\u0000DESIGN\u0000Point prevalence survey.\u0000\u0000\u0000SETTING\u00001417 ICU in 17 Western European countries.\u0000\u0000\u0000SUBJECTS\u000010038 patients in ICU who were part in the EPIC (European Prevalence of Infection in Intensive Care) Study.\u0000\u0000\u0000MAIN OUTCOME MEASURES\u0000Prevalence of MRSA and MSSA ICU-acquired infections, risk factors, and mortality.\u0000\u0000\u0000RESULTS\u0000On the study day 21% of patients had ICU-acquired infections. The most commonly reported pathogen was Staphylococcus aureus (30%). Overall, 60% of strains of S. aureus were resistant to methicillin (with a wide intercountry variation). The most commonly reported MRSA infections were pneumonia and lower respiratory tract infections. The most important risk factor for MRSA was the length of stay in the ICU. MRSA infection reduced the chance of survival, particularly when it was found in lower respiratory tract infections: the risk of mortality was three times higher in patients with MRSA than in those with MSSA.\u0000\u0000\u0000CONCLUSION\u0000Patients in ICU are at high risk of becoming infected with MRSA. The longer they stay, the higher the risk. Patients with MRSA infections are less likely to survive than those with MSSA.","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"164 6","pages":"411-418"},"PeriodicalIF":0.0,"publicationDate":"2003-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/110241598750004210","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20613210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yaron Assaff, Ibrahim Matter, Edmond Sabo, Jorge G. Mogilner, Ernest Nash, Jack Abrahamson, Samuel Eldar
{"title":"Laparoscopic cholecystectomy for acute cholecystitis and the consequences of gallbladder perforation, bile spillage, and “loss” of stones","authors":"Yaron Assaff, Ibrahim Matter, Edmond Sabo, Jorge G. Mogilner, Ernest Nash, Jack Abrahamson, Samuel Eldar","doi":"10.1080/110241598750004238","DOIUrl":"10.1080/110241598750004238","url":null,"abstract":"<div>\u0000 \u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective:</h3>\u0000 \u0000 <p>To study the factors associated with accidental perforation of the gallbladder and spillage of bile and stones and to assess the consequences of these mishaps.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design:</h3>\u0000 \u0000 <p>Prospective study with retrospective bacteriological evaluation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting:</h3>\u0000 \u0000 <p>Teaching hospital, Israel.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Subjects:</h3>\u0000 \u0000 <p>189 Patients who were treated for clinical acute cholecystitis between January 1994 and August 1996.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions:</h3>\u0000 \u0000 <p>Emergency laparoscopic cholecystectomy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main outcome measures:</h3>\u0000 \u0000 <p>Incidence of accidental perforation of gallbladder and spillage of bile and stones and of conversion and complications in relation to preoperative and operative findings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results:</h3>\u0000 \u0000 <p>Bile was spilt in 65 (34%) and gall-stones were “lost” in 27 (14%), 44 (23%) required conversion to an open approach and 36 (19%) developed complications. Preoperative duration of symptoms >96 hours and a palpable gallbladder were associated with accidental perforation of the gallbladder and spillage of bile. A palpable gallbladder, gangrenous cholecystitis, and WBC > 15 × 10<sup>9</sup>/L were associated with stones “lost” in the peritoneum. A history of biliary disease was inversely related to “lost” stones. Conversion of laparoscopic to open cholecystectomy was associated with male sex, age >60 years, a non-palpable gallbladder, WBC > 15 × 10<sup>9</sup>/L, and a gangrenous gallbladder. Complications of surgery were more common among men and associated with fever of >38°C. Neither the conversion nor the complications were associated with perforation of the gallbladder or “lost” stones.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion:</h3>\u0000 \u0000 <p>Perforation of the gallbladder and intraperitoneal spillage of bile or stones during laparoscopic cholecystectomy for acute cholecystitis are not associated with undesirable events, are not indications for conversion, and are not associated with further complications. When patients are given appropriate antibiotics perioperatively and the spilt bile is properly aspirated and the peritoneum irrigated, the operative and postoperative courses are similar to those of pat","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"164 6","pages":"425-431"},"PeriodicalIF":0.0,"publicationDate":"2003-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/110241598750004238","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20613693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editors: Hiatt JR, Phillips EH, Morgenstern L: Surgical disease of the spleen. Springer Verlag, Berlin, 1997 (113 figures, many in colour, and 24 tables. 285 pages). ISBN 3-54061-781-7","authors":"Lars Lundell","doi":"10.1080/110241598750004850","DOIUrl":"https://doi.org/10.1080/110241598750004850","url":null,"abstract":"","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"164 2","pages":"157"},"PeriodicalIF":0.0,"publicationDate":"2003-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/110241598750004850","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109229990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Shearman D. J. C., Finlayson N. D. C. and Camilleri M. (Eds). D. C. Carter (Surgical Ed): Diseases of the gastrointestinal tract and liver, 3rd ed. Edinburgh: Churchill Livingstone, 1997. (1500 pages). ISBN: 044305147X","authors":"Gunnar Järnerot","doi":"10.1080/110241598750004328","DOIUrl":"10.1080/110241598750004328","url":null,"abstract":"","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"164 6","pages":"477"},"PeriodicalIF":0.0,"publicationDate":"2003-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/110241598750004328","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"93392456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}