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Enfermedad Inflamatoria Intestinal al Día最新文献

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Mongersen, un SMAD7 «antisense» oligonucleótido y enfermedad de Crohn Mongersen, SMAD7“反义”寡核苷酸和克罗恩病
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-05-01 DOI: 10.1016/j.eii.2015.06.005
J. Profitós , A. Villoria , X. Calvet
{"title":"Mongersen, un SMAD7 «antisense» oligonucleótido y enfermedad de Crohn","authors":"J. Profitós , A. Villoria , X. Calvet","doi":"10.1016/j.eii.2015.06.005","DOIUrl":"10.1016/j.eii.2015.06.005","url":null,"abstract":"","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.06.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90189907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Papel actual de los inmunomoduladores convencionales en la enfermedad inflamatoria intestinal pediátrica 传统免疫调节剂在小儿炎症性肠病中的作用
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-05-01 DOI: 10.1016/j.eii.2015.06.003
G. Pujol Muncunill, J. Martín de Carpi
{"title":"Papel actual de los inmunomoduladores convencionales en la enfermedad inflamatoria intestinal pediátrica","authors":"G. Pujol Muncunill,&nbsp;J. Martín de Carpi","doi":"10.1016/j.eii.2015.06.003","DOIUrl":"https://doi.org/10.1016/j.eii.2015.06.003","url":null,"abstract":"<div><p>Pediatric Inflammatory Bowel Disease (P-IBD) has its own characteristics and early, intensive and sustained treatment is recommended. Immunomodulator treatment is indicated for maintenance of remission in P-CD (Pediatric Crohn's Disesase) treated with exclusive enteral nutrition (EEN) to induce remission and P-UC (Pediatric Ulcerative Colitis) that requires steroids to induce remission. Combo therapy is recommended for patients at high risk of complications; however, individualized treatment and the assessment of adverse events is mandatory. By now, the use of thiopurines is not justified for the prevention of loss of response to anti-TNF and antibody formation. Larger pediatric prospective studies are needed.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.06.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137161895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incontinencia fecal, el síntoma silencioso 大便失禁，无声症状
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-05-01 DOI: 10.1016/j.eii.2015.06.001
M.F. Murciano Gonzalo , M.P. González Gálvez
{"title":"Incontinencia fecal, el síntoma silencioso","authors":"M.F. Murciano Gonzalo ,&nbsp;M.P. González Gálvez","doi":"10.1016/j.eii.2015.06.001","DOIUrl":"10.1016/j.eii.2015.06.001","url":null,"abstract":"<div><h3>Objective</h3><p>To reflect on aspects related to faecal incontinence, the way it modifies the lifestyle of patients with inflammatory bowel disease (IBD) and the nurse's role in this process.</p></div><div><h3>Method</h3><p>Literature review of faecal incontinence and the relationship between the specialist nurse.</p></div><div><h3>Conclusions</h3><p>It is essential that patients are rest assured that fighting against faecal incontinence is not only their responsibility, but also the nurse plays an active role.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.06.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85331243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Niveles de microARN en plasma en pacientes con enfermedad de Crohn durante el tratamiento de inducción con infliximab 英夫利昔单抗诱导治疗期间克罗恩病患者血浆中microrna的水平
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-05-01 DOI: 10.1016/j.eii.2015.05.002
M. Iborra, B. Beltrán
{"title":"Niveles de microARN en plasma en pacientes con enfermedad de Crohn durante el tratamiento de inducción con infliximab","authors":"M. Iborra,&nbsp;B. Beltrán","doi":"10.1016/j.eii.2015.05.002","DOIUrl":"10.1016/j.eii.2015.05.002","url":null,"abstract":"","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.05.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82906094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Falsa hipersensibilidad a mesalazina como causa de escalamiento terapéutico 美沙拉嗪假过敏是治疗升级的原因
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-05-01 DOI: 10.1016/j.eii.2015.06.004
M. Calafat , N. Depreux , M. Mañosa , E. Cabré , L. Zacarías , E. Domènech
{"title":"Falsa hipersensibilidad a mesalazina como causa de escalamiento terapéutico","authors":"M. Calafat ,&nbsp;N. Depreux ,&nbsp;M. Mañosa ,&nbsp;E. Cabré ,&nbsp;L. Zacarías ,&nbsp;E. Domènech","doi":"10.1016/j.eii.2015.06.004","DOIUrl":"10.1016/j.eii.2015.06.004","url":null,"abstract":"<div><p>Mesalazine is the drug of choice in patients with mild-moderate forms of ulcerative colitis, both for inducing clinical remission and for maintenance. In fact, half of patients will be controlled with mesalazine only during their progress. It is overall considered a safe drug, with few adverse effects. Still, some cases of hypersensitivity to aminosalicylates of idiosyncratic nature have been described, which could lead to the withdrawal of the drug. This could notably limit the chances of therapeutic management, especially in patients with a mild or moderate activity or in those with exclusively rectal involvement. We present 2 cases of ulcerative proctitis where an allergy to mesalazine was suspected, what led to an inadequate control of the disease. Upon completion of the immunoallergic study the sensitivity was ruled out, the drug was reintroduced and fast and prolonged clinical remission was achieved.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.06.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89088471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Pancreatitis inducida por mesalacina en pacientes con enfermedad inflamatoria intestinal 炎症性肠病患者美沙拉星诱导的胰腺炎
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-01-01 DOI: 10.1016/j.eii.2015.01.001
M. Chaparro, V. Jusué, L. García-Buey, J.P. Gisbert
{"title":"Pancreatitis inducida por mesalacina en pacientes con enfermedad inflamatoria intestinal","authors":"M. Chaparro,&nbsp;V. Jusué,&nbsp;L. García-Buey,&nbsp;J.P. Gisbert","doi":"10.1016/j.eii.2015.01.001","DOIUrl":"10.1016/j.eii.2015.01.001","url":null,"abstract":"<div><p>Aminosalicylates are the drugs of first-choice in the management of patients with mild to moderate ulcerative colitis. In general they are safe and well-tolerated drugs. Nevertheless, cases have been described where a pancreatitis has developed as a possible complication of the treatment with aminosalicylates. It has been suggested that the mechanism these drugs use to induce inflammation on a pancreatic level is idiosyncratic. Conversely, even if cases of mesalazine-induced pancreatitis are usually mild, their recurrence rate is high, even when administered rectally. Therefore, a close monitoring must be carried out in the event that a patient who already suffered mesalazine-induced pancreatitis needs to be provided with the treatment again. We present the case of a patient with ulcerative colitis who developed a pancreatitis secondary to oral treatment with mesalazine; both the rectally administered mesalazine as well as a different formulation or oral mesalazine developed the recurrence of episodes of pancreatitis.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.01.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81379850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enfermedad inflamatoria intestinal: reflexiones 炎症性肠病:反思
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-01-01 DOI: 10.1016/j.eii.2015.04.001
M.À. Gassull
{"title":"Enfermedad inflamatoria intestinal: reflexiones","authors":"M.À. Gassull","doi":"10.1016/j.eii.2015.04.001","DOIUrl":"https://doi.org/10.1016/j.eii.2015.04.001","url":null,"abstract":"","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137254894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Normalización a largo plazo de la calidad de vida de los pacientes con enfermedad de Crohn con terapia de mantenimiento con adalimumab 阿达木单抗维持治疗克罗恩病患者生活质量的长期正常化
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-01-01 DOI: 10.1016/j.eii.2014.12.001
F. Casellas, C. Herrera de Guise, V. Robles, A. Torrejón, E. Navarro, N. Borruel
{"title":"Normalización a largo plazo de la calidad de vida de los pacientes con enfermedad de Crohn con terapia de mantenimiento con adalimumab","authors":"F. Casellas,&nbsp;C. Herrera de Guise,&nbsp;V. Robles,&nbsp;A. Torrejón,&nbsp;E. Navarro,&nbsp;N. Borruel","doi":"10.1016/j.eii.2014.12.001","DOIUrl":"10.1016/j.eii.2014.12.001","url":null,"abstract":"<div><h3>Background</h3><p>Maintenance treatment of Crohn's disease (CD) with adalimumab achieves sustained clinical remission and improves health-related quality of life (HRQOL) of patients. There is, however, no information about its long-term effect on normalization of patient's perceived health.</p></div><div><h3>Objectives</h3><p>To determine the long-term normal perception of health in CD patients in clinical remission with adalimumab.</p></div><div><h3>Methods</h3><p>Retrospective, observational study in CD patients in clinical remission for 36 months follow-up, treated with adalimumab 40<!--> <!-->mg eow. Patients requiring a change of treatment or surgery were not included. HRQOL was assessed with the specific questionnaire IBDQ-36. The normalization of health was defined as an overall score ≥ 209.</p></div><div><h3>Results</h3><p>Twenty eight patients were included in sustained clinical remission for 36 months. Three patients required further escalation and de-escalation of the dose. The IBDQ-36 overall score remained unchanged in patients with inactive stable CD and even tended to increase with time (median overall score of 230 at 6 months and 238 at 3 years). The rate of normalization of health increased with time (68% to 78% at 6 and 36 months respectively).</p></div><div><h3>Conclusions</h3><p>Sustained clinical remission with effective maintenance treatment with adalimumab restores the perception of normal health of most of the patients with CD.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2014.12.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89268849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigación básica 基础研究
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-01-01 DOI: 10.1016/j.eii.2015.02.004
L. Menchén Viso
{"title":"Investigación básica","authors":"L. Menchén Viso","doi":"10.1016/j.eii.2015.02.004","DOIUrl":"https://doi.org/10.1016/j.eii.2015.02.004","url":null,"abstract":"","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.02.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137310900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
El caso de la estandarización de la calprotectina fecal, o cómo evitar que el entusiasmo nos lleve a la confusión 粪便钙保护素标准化的案例，或如何避免热情导致我们困惑
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-01-01 DOI: 10.1016/j.eii.2015.02.005
Y. González-Lama
{"title":"El caso de la estandarización de la calprotectina fecal, o cómo evitar que el entusiasmo nos lleve a la confusión","authors":"Y. González-Lama","doi":"10.1016/j.eii.2015.02.005","DOIUrl":"10.1016/j.eii.2015.02.005","url":null,"abstract":"","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.02.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88438745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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