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Dipropionato de beclometasona oral de liberación modificada y prednisona para el tratamiento de la colitis ulcerosa activa: resultados de un estudio doble ciego, aleatorizado y de grupos paralelos 双丙酸缓释倍氯米松口服强的松治疗活动性溃疡性结肠炎:双盲、随机、平行组研究结果
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2016-01-01 DOI: 10.1016/j.eii.2016.02.001
I. Rodríguez-Lago, J.L. Cabriada
{"title":"Dipropionato de beclometasona oral de liberación modificada y prednisona para el tratamiento de la colitis ulcerosa activa: resultados de un estudio doble ciego, aleatorizado y de grupos paralelos","authors":"I. Rodríguez-Lago, J.L. Cabriada","doi":"10.1016/j.eii.2016.02.001","DOIUrl":"10.1016/j.eii.2016.02.001","url":null,"abstract":"","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"15 1","pages":"Pages 31-33"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2016.02.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83601535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ileocolitis de Crohn refractaria secundaria a colitis amebiana: un caso clínico 阿米巴结肠炎继发的难治性克罗恩回肠结肠炎:一个临床病例
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2016-01-01 DOI: 10.1016/j.eii.2016.01.002
M.D. Martín Arranz , L. Guerra Pastrian
{"title":"Ileocolitis de Crohn refractaria secundaria a colitis amebiana: un caso clínico","authors":"M.D. Martín Arranz ,&nbsp;L. Guerra Pastrian","doi":"10.1016/j.eii.2016.01.002","DOIUrl":"10.1016/j.eii.2016.01.002","url":null,"abstract":"<div><p>Up to 30% of patients with Crohn's disease are refractory to corticoesteroids. Currently, these patients are treated with inmunosupressive or biologic therapies or surgery. A proper differential diagnosis must be established knowing that many infections can mimic inflamatory bowel disease, and the diagnosis is not always easy. A case of an ileocolonic Crohn's disease refractory to corticosteroid because an Entamoeba histolytica infection in a patient without epidemiologic risk factors is presented.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"15 1","pages":"Pages 15-18"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2016.01.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88232605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inmunogenicidad cruzada: anticuerpos para infliximab en pacientes con enfermedad inflamatoria intestinal tratados con Remicade reconocen similarmente al biosimilar Remsima 交叉免疫原性:在使用Remicade治疗的炎症性肠病患者中，英夫利昔单抗抗体识别的生物类似物Remsima相似
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2016-01-01 DOI: 10.1016/j.eii.2015.12.002
J.R. Márquez Velásquez
{"title":"Inmunogenicidad cruzada: anticuerpos para infliximab en pacientes con enfermedad inflamatoria intestinal tratados con Remicade reconocen similarmente al biosimilar Remsima","authors":"J.R. Márquez Velásquez","doi":"10.1016/j.eii.2015.12.002","DOIUrl":"10.1016/j.eii.2015.12.002","url":null,"abstract":"","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"15 1","pages":"Pages 19-21"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.12.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83818600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Fiebre persistente en paciente con enfermedad de Crohn: enfermedad de Still del adulto 克罗恩病患者持续发热:成人斯蒂尔氏病
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-09-01 DOI: 10.1016/j.eii.2015.09.002
L. Carrión-Martín , G. Pérez-Rial , A.I. Hernando-Alonso , L. Menchén-Viso , J. Pajares-Díaz , F.J. López-Longo , M. Valerio , M.J. Penalva-Moreno , I. Marín-Jimenez
{"title":"Fiebre persistente en paciente con enfermedad de Crohn: enfermedad de Still del adulto","authors":"L. Carrión-Martín ,&nbsp;G. Pérez-Rial ,&nbsp;A.I. Hernando-Alonso ,&nbsp;L. Menchén-Viso ,&nbsp;J. Pajares-Díaz ,&nbsp;F.J. López-Longo ,&nbsp;M. Valerio ,&nbsp;M.J. Penalva-Moreno ,&nbsp;I. Marín-Jimenez","doi":"10.1016/j.eii.2015.09.002","DOIUrl":"10.1016/j.eii.2015.09.002","url":null,"abstract":"<div><p>Extra-intestinal manifestations are frequent in Crohn's disease (CD). Adult onset Still's disease is a rare disease presenting with arthritis and arthralgia, high (<!--> <!-->&gt;<!--> <!-->39<!--> <!-->°C) and persistent fever, rash, sore throat, lymphadenopathies and hepatosplenomegaly. There are only 3 cases in literature of adult onset Still's disease presenting in CD patients. We describe a new case of adult onset Still's disease associated to connective tissue disease. Although infrequent, it is important to become aware of this disease for the differential diagnosis of arthralgia and high fever in CD patients.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"14 3","pages":"Pages 105-108"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.09.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90874609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colitis microscópica y exposición a fármacos: una revisión crítica 显微结肠炎与药物暴露:综述
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-09-01 DOI: 10.1016/j.eii.2015.08.004
A.J. Lucendo , F. Fernández-Bañares
{"title":"Colitis microscópica y exposición a fármacos: una revisión crítica","authors":"A.J. Lucendo ,&nbsp;F. Fernández-Bañares","doi":"10.1016/j.eii.2015.08.004","DOIUrl":"10.1016/j.eii.2015.08.004","url":null,"abstract":"<div><p>Microscopic colitis (MC) comprises 2 fundamental entities (lymphocytic colitis and collagenous colitis) defined by chronic or recurrent watery diarrhea, normal colonoscopy and characteristic histopathological features. The exposure of the colonic mucosa at different luminal antigens, including different drugs, has been involved in the still poor understood pathophysiology of MC. Thus, the relationship between the development of MC after drug exposure has been the subject of research for more than 2 decades, mainly based on observational studies, including case reports and case series, case-control studies, and data on drug prescriptions. Among others, proton-pump inhibitors, nonsteroidal antiinflammatory drugs, selective inhibitors of serotonin reuptake, beta-blockers and statins, have been linked to the onset of MC, but all these drugs are also recognized as a frequent cause of drug-associated diarrhea.</p><p>At present we have no universally accepted criteria for establishing cause-effect relationships in adverse drug reactions, although several methods have provide us with different levels of likelihood. Thus, the existence of a high probability of MC occurrence as an adverse effect to a specific drug has been shown only in individual cases by using chronological (exposure, effect of withdrawal and relapse with re-exposure) and semiological criteria. Although case-control studies have repeatedly shown significant associations between drug exposure and MC, variability in their designs, including reference populations used and the criteria considered in defining drug exposure, requires a detailed analysis. This article critically examines the complex relationship between drugs, diarrhea and MC, to conclude that a likely cause-effect relationship has only been described for few drugs and in individual cases of MC.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"14 3","pages":"Pages 94-104"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.08.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84316711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Manejo perioperatorio de la enfermedad inflamatoria intestinal 炎症性肠病的围手术期管理
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-09-01 DOI: 10.1016/j.eii.2015.08.003
J. de Oca , F. Rodríguez-Moranta , E. de Lama , J. Guardiola
{"title":"Manejo perioperatorio de la enfermedad inflamatoria intestinal","authors":"J. de Oca ,&nbsp;F. Rodríguez-Moranta ,&nbsp;E. de Lama ,&nbsp;J. Guardiola","doi":"10.1016/j.eii.2015.08.003","DOIUrl":"10.1016/j.eii.2015.08.003","url":null,"abstract":"<div><h3>Introduction</h3><p>An important percentage of patients with inflammatory bowel disease will require surgical treatment at some point. Despite technological progress in the surgical and anaesthetic fields, figures for postoperative morbidity are still high. This alone requires a comprehensive review of perioperative protocols that will allow better surgical results.</p></div><div><h3>Objective</h3><p>To update all organisational and therapeutic measures that have proven to be effective when it comes to optimising the perioperative period.</p></div><div><h3>Methods</h3><p>Review of literature related to postoperative morbidity, immunosupression, radiology, nutrition, multidisciplinary teams and multimodal rehabilitation protocols.</p></div><div><h3>Results</h3><p>Management of inflammatory bowel disease, especially during the perioperative period, requires the coordinated action of a multidisciplinary team with a specific dedication to this condition. The surgical decision must be agreed upon clinical criteria and reinforced by means of modern imaging techniques. Sepsis, malnutrition and prolonged corticoid therapy have shown to be the principal determining factors for morbimortality after surgery. The presence of an abscess requires percutaneous drainage followed by surgery. Malnutrition states require aggressive nutritional therapy before the surgery and, whenever possible, the corticoid dosage should be reduced. Compliance with the current ERAS multimodal rehabilitation protocols can help shorten the admission period after surgery and offer an efficient and viable alternative for improving the postoperative period and the quality of life for patients.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"14 3","pages":"Pages 87-93"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.08.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79450767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Manifestaciones tromboembólicas en enfermedad inflamatoria intestinal 炎症性肠病的血栓栓塞表现
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-09-01 DOI: 10.1016/j.eii.2015.08.002
A. Campos Ruiz , P. Ramirez de la Piscina Urraca , I. Ganchegui Aguirre , L. Urtasun Arlegui , A. Sanchez Patón , K. Spicakova , I.M. Duca Duca , S. Estrada Oncins , E. Delgado Fontaneda , M. Salvador Perez , B. Rodriguez Vigil
{"title":"Manifestaciones tromboembólicas en enfermedad inflamatoria intestinal","authors":"A. Campos Ruiz ,&nbsp;P. Ramirez de la Piscina Urraca ,&nbsp;I. Ganchegui Aguirre ,&nbsp;L. Urtasun Arlegui ,&nbsp;A. Sanchez Patón ,&nbsp;K. Spicakova ,&nbsp;I.M. Duca Duca ,&nbsp;S. Estrada Oncins ,&nbsp;E. Delgado Fontaneda ,&nbsp;M. Salvador Perez ,&nbsp;B. Rodriguez Vigil","doi":"10.1016/j.eii.2015.08.002","DOIUrl":"10.1016/j.eii.2015.08.002","url":null,"abstract":"<div><p>Inflammatory bowel disease (IBD) is a systemic chronic disease, which in some cases is associated with thromboembolic events. Although these events are uncommon, they are increased in patients with IBD and increase morbidity and mortality.While IBD is active there are modifications in the coagulation system, thus inducing a hypercoagulable state and a risk of developing thrombotic events which are not present in patients with inactive IBD.It is essential to identify which patients have a higher risk of developing a thrombotic event and establish appropriate prophylaxis as early as possible.We present some cases of patients diagnosed with IBD who developed vascular complications in the course of their disease and we review the existing literature.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"14 3","pages":"Pages 81-86"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.08.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78192477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cómo los estudios traslacionales asociados a ensayos clínicos pueden mejorar nuestro conocimiento de las enfermedades inflamatorias 与临床试验相关的转化研究如何提高我们对炎症疾病的认识
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-09-01 DOI: 10.1016/j.eii.2015.08.001
J. Panés
{"title":"Cómo los estudios traslacionales asociados a ensayos clínicos pueden mejorar nuestro conocimiento de las enfermedades inflamatorias","authors":"J. Panés","doi":"10.1016/j.eii.2015.08.001","DOIUrl":"10.1016/j.eii.2015.08.001","url":null,"abstract":"","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"14 3","pages":"Pages 79-80"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76435682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comentarios sobre estudios multicéntricos aleatorizados para colitis ulcerosa en fase IIa IIa期溃疡性结肠炎随机多中心研究综述
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-05-01 DOI: 10.1016/j.eii.2015.05.001
A. Gutiérrez Casbas
{"title":"Comentarios sobre estudios multicéntricos aleatorizados para colitis ulcerosa en fase IIa","authors":"A. Gutiérrez Casbas","doi":"10.1016/j.eii.2015.05.001","DOIUrl":"10.1016/j.eii.2015.05.001","url":null,"abstract":"","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"14 2","pages":"Pages 76-78"},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.05.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91489775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recomendaciones sobre el uso e indicaciones del tratamiento tópico en pacientes con colitis ulcerosa 溃疡性结肠炎患者局部治疗的使用建议和适应症
Enfermedad Inflamatoria Intestinal al Día Pub Date : 2015-05-01 DOI: 10.1016/j.eii.2015.06.002
D. Ginard , I. Marín-Jiménez , M. Barreiro de Acosta , E. Ricart , E. Domènech , J.P. Gisbert , M. Esteve , M. Mínguez , en representación de GETECCU
{"title":"Recomendaciones sobre el uso e indicaciones del tratamiento tópico en pacientes con colitis ulcerosa","authors":"D. Ginard ,&nbsp;I. Marín-Jiménez ,&nbsp;M. Barreiro de Acosta ,&nbsp;E. Ricart ,&nbsp;E. Domènech ,&nbsp;J.P. Gisbert ,&nbsp;M. Esteve ,&nbsp;M. Mínguez ,&nbsp;en representación de GETECCU","doi":"10.1016/j.eii.2015.06.002","DOIUrl":"https://doi.org/10.1016/j.eii.2015.06.002","url":null,"abstract":"<div><p>Although most patients with ulcerative colitis should be treated with topical treatment, different studies have shown that they are underused. The purpose of this article is to answer 10 specific questions about which drugs are available for topical use in the treatment of ulcerative colitis, and their characteristics in terms of formulation, dosage, presentation, application and proximal distribution of rectal-administered drugs. The efficacy of the available topical drugs and the benefits of combining different formulations and routes of administration, and their usefulness during disease remission is evaluated. Finally, some recommendations are given to better inform patients about the proper implementation and administration of topical treatment.</p></div>","PeriodicalId":100473,"journal":{"name":"Enfermedad Inflamatoria Intestinal al Día","volume":"14 2","pages":"Pages 41-47"},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eii.2015.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137161896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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