EAU Update Series最新文献_第4页

Neuromodulation—Sacral, Peripheral and Central: Current Status, Indications, Results and New Developments 神经调节-骶、外周和中枢:现状、适应症、结果和新进展

EAU Update Series Pub Date : 2004-12-01 Epub Date: 2004-11-02 DOI: 10.1016/j.euus.2004.09.005

Peter Martin Braun, Christoph Seif, Christof van der Horst, Klaus-Peter Jünemann

{"title":"Neuromodulation—Sacral, Peripheral and Central: Current Status, Indications, Results and New Developments","authors":"Peter Martin Braun, Christoph Seif, Christof van der Horst, Klaus-Peter Jünemann","doi":"10.1016/j.euus.2004.09.005","DOIUrl":"10.1016/j.euus.2004.09.005","url":null,"abstract":"<div><p>This article provides basic information on the current status in sacral, peripheral and central neuromodulation techniques.</p><p>Sacral neuromodulation has been a well-established method for treatment of urinary dysfunction for over 15 years. While it has proved itself to be a long-term successful method of treatment for patients with neurogenic or non-neurogenic overactive bladder (OAB) or chronic retention, many patients are excluded from this beneficial therapy form, as the peripheral nerve evaluation (PNE) test carried out prior to implantation of a permanent neuromodulator still produces non-responder rates of 50% or more. The new two-stage approach developed by Spinelli et al. gives rise to the hope that some problems connected to the PNE test can be overcome through use of the final electrodes during the test. The bion technique, moreover, a brand new technological development for peripheral neuromodulation, may produce new and interesting results in the future. Finally, research is under way for a third neuromodulation approach of direct stimulation in the pontine micturition center, as investigations in Parkinson patients have shown that the incontinence situation can be improved significantly by activation of the deep brain stimulator.</p></div>","PeriodicalId":100385,"journal":{"name":"EAU Update Series","volume":"2 4","pages":"Pages 187-194"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.euus.2004.09.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73172379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Comparison of Peripherally Acting Substance for Treatment of Detrusor Overactivity: What is New; What is in the Pipeline? 外周作用物质治疗逼尿肌过度活动的比较:新进展正在进行的工作是什么?

EAU Update Series Pub Date : 2004-12-01 Epub Date: 2004-10-19 DOI: 10.1016/j.euus.2004.09.001

Andrea Tubaro, Cosimo De Nunzio

{"title":"Comparison of Peripherally Acting Substance for Treatment of Detrusor Overactivity: What is New; What is in the Pipeline?","authors":"Andrea Tubaro, Cosimo De Nunzio","doi":"10.1016/j.euus.2004.09.001","DOIUrl":"10.1016/j.euus.2004.09.001","url":null,"abstract":"<div><h3>Objective:</h3><p>Overactive bladder is an highly prevalent syndrome involving up to 17% of the population in both western Europe and US and is often associated with detrusor overactivity. Significant improvement in the management of this condition has recently occurred cause the availability of new drugs.</p></div><div><h3>Methods:</h3><p>The Medline database has been extensively searched. Research has also involved industrial and private databases available online and specialised in the development of new drugs.</p></div><div><h3>Results:</h3><p>Antimuscarinics remain the gold standard in the management of detrusor overactivity although the condition mostly goes undiagnosed in non neurogenic patients suffering from overactive bladder syndrome. A number of receptors other than muscarinics have been investigated as possible new targets although no novel effective drugs have been yet developed.</p></div><div><h3>Conclusion:</h3><p>Antimuscarinic drugs dominate medical treatment of symptoms and signs associated with detrusor overactivity although new drugs will hopefully be available in the future based on alternative pathophysiological mechanism.</p></div>","PeriodicalId":100385,"journal":{"name":"EAU Update Series","volume":"2 4","pages":"Pages 161-169"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.euus.2004.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80888603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Botox in Urology: A New Treatment Modality without Limitations? 肉毒杆菌毒素在泌尿外科:一种没有限制的新治疗方式?

EAU Update Series Pub Date : 2004-12-01 Epub Date: 2004-10-19 DOI: 10.1016/j.euus.2004.09.004

Brigitte Schurch, André Reitz

引用次数: 17

New Understanding of Central and Peripheral Interaction between Bladder and Sphincter Function 膀胱和括约肌功能中枢和外周相互作用的新认识

EAU Update Series Pub Date : 2004-12-01 Epub Date: 2004-10-28 DOI: 10.1016/j.euus.2004.09.003

André Reitz , Björn Wefer , Brigitte Schurch

引用次数: 3

Neurourology 神经泌尿学

EAU Update Series Pub Date : 2004-12-01 Epub Date: 2004-11-20 DOI: 10.1016/j.euus.2004.10.001

Klaus-Peter Jünemann

引用次数: 0

Pelvic Pain and Interstitial Cystitis: Therapeutic Strategies, Results and Limitations 盆腔疼痛和间质性膀胱炎:治疗策略、结果和局限性

EAU Update Series Pub Date : 2004-12-01 Epub Date: 2004-10-19 DOI: 10.1016/j.euus.2004.09.002

Jørgen Nordling

{"title":"Pelvic Pain and Interstitial Cystitis: Therapeutic Strategies, Results and Limitations","authors":"Jørgen Nordling","doi":"10.1016/j.euus.2004.09.002","DOIUrl":"10.1016/j.euus.2004.09.002","url":null,"abstract":"<div><p>Interstitial cystitis is a chronic disease characterized by bladder pain, frequency and urgency. Because of lack of definition and specific diagnostic criteria terminology today changes towards Painful Bladder Syndrome (PBS) reserving the diagnosis Interstitial Cystitis (IC) for a disease with typical cystoscopic and histological features yet to be defined.</p></div><div><h3>Diagnosis and evaluation.</h3><p>Patients with bladder pain, frequency and urgency must have other pathologies like bacterial, radiation or chemical cystitis, pelvic tumors, infravesical obstruction or urethral diverticula excluded by examination of the urine, endoscopy or other relevant investigations. Evaluation by cystoscopy in general anaesthesia with bladder distension and bladder biopsy gives information on presence of Hunner's ulcer, glomerulations, bladder capacity and bladder wall inflammation, which have influence on treatment strategy and prognosis.</p></div><div><h3>Treatment.</h3><p>An abundance of treatments have been suggested, but very few have been subjected to proper controlled trials. Patient counseling and instructions in self care and dietary initiatives are important. Physical therapy for primary or secondary myofascial tensions in the pelvis might be helpful. Oral treatment with antihistamines and pentosanpolysulphate is well established, while leucotriene receptor antagonists, cyclosporine and many others are still investigational. Bladder irrigation with DMSO, hyaloronic acid and heparin is widely used, while BCG, lidocain, capsaicin and RTX have been reported. Pain treatment spans from mild analgesics over tricyclic antidepressants (amitryptylin) and antiepileptics (gabapentin) to opioids. Surgical intervention includes bladder distension, resection of Hunner's ulcer, bladder augmentation, urinary diversion and cystectomy depending on disease severity and symptomatology.</p></div>","PeriodicalId":100385,"journal":{"name":"EAU Update Series","volume":"2 4","pages":"Pages 179-186"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.euus.2004.09.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73849729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Bacteriuria and Prophylaxis 细菌尿和预防

EAU Update Series Pub Date : 2004-09-01 Epub Date: 2004-09-11 DOI: 10.1016/j.euus.2004.08.002

Truls E. Bjerklund Johansen

引用次数: 1

Uncomplicated Urinary Tract Infection 无并发症尿路感染

EAU Update Series Pub Date : 2004-09-01 Epub Date: 2004-09-15 DOI: 10.1016/j.euus.2004.08.003

M.C. Bishop

引用次数: 9

Antibiotics and Resistance of Uropathogens 抗生素与尿路病原菌耐药性

EAU Update Series Pub Date : 2004-09-01 Epub Date: 2004-07-29 DOI: 10.1016/j.euus.2004.06.003

F.M.E. Wagenlehner, K.G. Naber

引用次数: 21

Application of Laboratory Research in UTI 实验室研究在尿路感染中的应用

EAU Update Series Pub Date : 2004-09-01 Epub Date: 2004-08-04 DOI: 10.1016/j.euus.2004.06.004

Björn Wullt , Göran Bergsten , Hans Fischer

引用次数: 9