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Robotic-assisted sacrocolpopexy (RASC) in a renal transplant patient with Ehlers-Danlos syndrome (EDS), case report and literature review of perioperative considerations 机器人辅助骶colpopexy (RASC)治疗肾移植患者ehers - danlos综合征(EDS),病例报告及围手术期注意事项的文献回顾
IF 0.5
Continence Reports Pub Date : 2025-08-21 DOI: 10.1016/j.contre.2025.100090
Dina El-Hamamsy , Bénedicte Persyn , Steven E. Schraffordt Koops
{"title":"Robotic-assisted sacrocolpopexy (RASC) in a renal transplant patient with Ehlers-Danlos syndrome (EDS), case report and literature review of perioperative considerations","authors":"Dina El-Hamamsy ,&nbsp;Bénedicte Persyn ,&nbsp;Steven E. Schraffordt Koops","doi":"10.1016/j.contre.2025.100090","DOIUrl":"10.1016/j.contre.2025.100090","url":null,"abstract":"<div><div>With aging populations and advances of healthcare, patients with complex medical histories are more likely to present to our Urogynaecological practices. Similarly, with surgical advances, robotic-assisted surgery is currently gaining momentum with a view to improving surgical precision and potentially patient outcomes. Here, we present the first robotic-assisted sacrocolpopexy in a renal transplant patient with Ehlers-Danlos syndrome, and review the literature for perioperative considerations in these patients.</div><div>Our 51 year old patient presented with obstructive micturition due to advanced pelvic organ prolapse (POP). A pre-operative diagnostic laparoscopy was performed to evaluate abdominal accessibility and aid decision regarding surgical approach for prolapse repair. An uncomplicated robotic assisted sacrocolpopexy was performed with uneventful postoperative recovery, no prolapse recurrence and improved quality of life at 1 year follow-up.</div><div>When surgical repair is indicated in patients with POP after renal transplantation, in most cases vaginal approach will be chosen for primary surgery. Patients at high risk of recurrence of POP, such as the case described here, may benefit from abdominal approach. However, there is limited evidence on safety, feasibility and long-term outcomes following minimally-invasive abdominal POP repair in these cases. We conclude that robotic-assisted approach is feasible and could improve patient outcomes. However, more evidence needs to be generated to support such practice in high-risk patients. We call upon specialist societies to utilize surgical databases to support such cause.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"15 ","pages":"Article 100090"},"PeriodicalIF":0.5,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144894870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multidisciplinary conferences to enhance care for pelvic floor dysfunction: A descriptive study at a tertiary center 多学科会议加强对骨盆底功能障碍的护理:三级中心的描述性研究
IF 0.5
Continence Reports Pub Date : 2025-08-15 DOI: 10.1016/j.contre.2025.100089
Nouf Yahya Akeel , Leila Neshatian , Vipul Sheth , Ekene Enemchukwu , Sydni Au Hoy , Brooke H. Gurland , Stanford Pelvic Health Center Workgroup, Diana Atashroo , Yosef Chodakiewitz , Jimmy Dinh , Haddas Elisha , Patricia A. Garcia , Jennifer M. Hah , Ruth Hicks , Negaur Iranpour , Karen Jazmin , Zaineh Khalil , Michelle J. Khan , Natalie N. Kirilcuk , Kavita Mishra , Molly O'Brien-Horn
{"title":"Multidisciplinary conferences to enhance care for pelvic floor dysfunction: A descriptive study at a tertiary center","authors":"Nouf Yahya Akeel ,&nbsp;Leila Neshatian ,&nbsp;Vipul Sheth ,&nbsp;Ekene Enemchukwu ,&nbsp;Sydni Au Hoy ,&nbsp;Brooke H. Gurland ,&nbsp;Stanford Pelvic Health Center Workgroup,&nbsp;Diana Atashroo ,&nbsp;Yosef Chodakiewitz ,&nbsp;Jimmy Dinh ,&nbsp;Haddas Elisha ,&nbsp;Patricia A. Garcia ,&nbsp;Jennifer M. Hah ,&nbsp;Ruth Hicks ,&nbsp;Negaur Iranpour ,&nbsp;Karen Jazmin ,&nbsp;Zaineh Khalil ,&nbsp;Michelle J. Khan ,&nbsp;Natalie N. Kirilcuk ,&nbsp;Kavita Mishra ,&nbsp;Molly O'Brien-Horn","doi":"10.1016/j.contre.2025.100089","DOIUrl":"10.1016/j.contre.2025.100089","url":null,"abstract":"<div><h3>Purpose/background</h3><div>The multidisciplinary approach to pelvic floor disorders has been shown to improve patient care outcomes but remains underutilized. This study aims to assess the utility of multidisciplinary meetings for pelvic floor patients by prospectively evaluating their impact on diagnosis, management, and treatment planning. The specific objectives are to improve diagnostic accuracy, optimize treatment plans, and facilitate efficient resource allocation.</div></div><div><h3>Methods/interventions</h3><div>This is a descriptive study conducted at a tertiary referral academic center. Multidisciplinary conferences were held monthly by a collaborative clinical team. The meetings aimed to: 1. Comprehensively review radiological findings. 2. Develop individualized care plans. 3. Optimize surgical plans and combined surgery. The patients were identified from the pelvic floor multidisciplinary database. \"Utility\" will be measured by metrics including: 1) Rate of amendment to radiology reports, indicating improved diagnostic accuracy; 2) Frequency of recommended further assessment or workup, reflecting enhanced care pathway definition; and 3) Documentation of changes to the initial treatment plan based on multidisciplinary discussion, showing impact on management.</div></div><div><h3>Results/outcomes</h3><div>Nineteen multidisciplinary meetings were conducted between August 2021 and May 2023, discussing 101 cases. The patients were categorized into prolapse (n = 41), functional disorders (n = 38), and miscellaneous (n = 22) groups. The prolapse group was classified into combined rectal and pelvic organ prolapse (n = 22), and isolated rectal prolapse (n = 19). After each case discussion, a comprehensive review note was created and incorporated into the patient's chart, facilitating the initiation of follow-up plans and the coordination of services. Radiology reports were amended in 18 cases (18 %), with the majority of revisions related to rectal prolapse (n = 15, 83 %). Further assessment and workup were recommended in 17 cases (17 %): prolapse (n = 5), miscellaneous (n = 9), and motility (n = 3).</div></div><div><h3>Conclusion/discussion</h3><div>This study suggests that multidisciplinary meetings are beneficial in complex pelvic health conditions. They correlate clinical assessment with radiological findings and inform individualized treatment plans, as evidenced by the rates of amended radiology reports and recommended further assessment/workup. Further research is needed to quantitatively assess the long-term clinical outcomes and cost-effectiveness of this approach.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"16 ","pages":"Article 100089"},"PeriodicalIF":0.5,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145007799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trifecta outcomes in surgical treatment of male stress urinary incontinence 手术治疗男性压力性尿失禁的三合一效果
Continence Reports Pub Date : 2025-07-17 DOI: 10.1016/j.contre.2025.100088
Andrey Tomilov , Bagrat Grigoryan , George Kasyan , Evgeniy Veliev , Dmitry Pushkar
{"title":"Trifecta outcomes in surgical treatment of male stress urinary incontinence","authors":"Andrey Tomilov ,&nbsp;Bagrat Grigoryan ,&nbsp;George Kasyan ,&nbsp;Evgeniy Veliev ,&nbsp;Dmitry Pushkar","doi":"10.1016/j.contre.2025.100088","DOIUrl":"10.1016/j.contre.2025.100088","url":null,"abstract":"<div><h3>Introduction and objective</h3><div>Stress urinary incontinence (SUI) remains a significant challenge in male patients, particularly following prostate surgery. Despite advancements in surgical techniques and technologies, a standardized method for evaluating treatment success remains under discussion. This study aims to propose a conceptual and comprehensive model that incorporates three key outcomes: quality of life, urinary leakage control, and safety, to provide a structured approach to the assessment of surgical interventions for SUI.</div></div><div><h3>Evidence acquisition</h3><div>A literature review was conducted, focusing on clinical guidelines and outcome measures used in studies of SUI treatment. Key parameters were selected based on their relevance to patient satisfaction, clinical practice, and international standards, including the International Continence Society (ICS) and patient-reported outcomes (PROs).</div></div><div><h3>Results</h3><div>The proposed trifecta model includes three essential criteria: (1) Quality of life, assessed by the Visual Numeric Scale (VNS) with scores of 0–2 indicating significant improvement; (2) Urinary leakage control, defined as “social continence” (use of 0–1 pad per day), reflecting practical success; and (3) Safety, evaluated by the absence of complications within 90 days postoperatively, aligning with standard follow-up timelines. This model addresses both objective and subjective outcomes. While it does not encompass long-term results, the trifecta is adaptable for extended evaluations at 1, 5, and 10 years and serves as a conceptual framework requiring future clinical validation.</div></div><div><h3>Conclusion</h3><div>The proposed trifecta model suggests a patient-centered framework to evaluate the outcomes of surgical interventions for SUI. By addressing critical domains, it offers a structured method for clinical and research assessment. However, its clinical applicability requires confirmation through prospective validation in diverse patient cohorts.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"15 ","pages":"Article 100088"},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of intra-vaginal diazepam for pelvic floor hypertonic disorder: A systematic review and meta-analysis 阴道内使用地西泮治疗盆底高渗症的疗效:一项系统回顾和荟萃分析
Continence Reports Pub Date : 2025-07-10 DOI: 10.1016/j.contre.2025.100087
Dana Sawan , Mersal Almanasif , Sarah Alharshan , Rasha Alanazi , Sadeen Fallatah , Wasan Alanazi , Nora Aloufi
{"title":"Efficacy of intra-vaginal diazepam for pelvic floor hypertonic disorder: A systematic review and meta-analysis","authors":"Dana Sawan ,&nbsp;Mersal Almanasif ,&nbsp;Sarah Alharshan ,&nbsp;Rasha Alanazi ,&nbsp;Sadeen Fallatah ,&nbsp;Wasan Alanazi ,&nbsp;Nora Aloufi","doi":"10.1016/j.contre.2025.100087","DOIUrl":"10.1016/j.contre.2025.100087","url":null,"abstract":"<div><h3>Background</h3><div>High-tone pelvic floor dysfunction (HTPFD) is a neuromuscular disorder characterized by involuntary spasms of the levator ani muscles, often resulting in pelvic pain, dyspareunia, and bladder or bowel dysfunction. It is frequently associated with syndromes such as vulvodynia, interstitial cystitis, and pelvic myofascial pain. Current treatment options, including pelvic floor physical therapy and pharmacologic interventions, have limited evidence supporting their efficacy.</div></div><div><h3>Objective</h3><div>To assess the effectiveness of intra-vaginal diazepam suppositories in reducing pelvic floor muscle tone and alleviating associated symptoms in women with HTPFD.</div></div><div><h3>Methods</h3><div>A triple-blinded, randomized, placebo-controlled trial was conducted per PRISMA guidelines and registered in PROSPERO. Women aged ≥18 years with EMG-confirmed HTPFD were randomized to receive either 10 mg of diazepam or placebo vaginal suppositories nightly for 28 days. Primary outcomes included changes in resting pelvic floor electromyography (EMG). Secondary outcomes evaluated sexual function, pain levels, and quality of life via validated questionnaires.</div></div><div><h3>Results</h3><div>Twenty-one women were enrolled; 14 completed the trial (7 per arm). No statistically significant differences were observed between groups in resting EMG readings or subjective symptom scores. Both groups reported minor, non-significant improvements in pain and quality of life.</div></div><div><h3>Conclusion</h3><div>Current evidence is insufficient to determine the efficacy of intra vaginal diazepam for high tone pelvic floor dysfunction. Further large, well powered randomized controlled trials are needed to clarify its therapeutic role.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"15 ","pages":"Article 100087"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parameters which predict detrusor overactivity after adjustable trans obturator male system (ATOMS) implant. 可调节的男性经闭孔系统(ATOMS)植入后预测逼尿肌过度活动的参数。
Continence Reports Pub Date : 2025-05-13 DOI: 10.1016/j.contre.2025.100084
Miguel Vírseda-Chamorrro , Sonia Ruiz-Graña , Jesús Salinas-Casado , Javier Angulo Cuesta
{"title":"Parameters which predict detrusor overactivity after adjustable trans obturator male system (ATOMS) implant.","authors":"Miguel Vírseda-Chamorrro ,&nbsp;Sonia Ruiz-Graña ,&nbsp;Jesús Salinas-Casado ,&nbsp;Javier Angulo Cuesta","doi":"10.1016/j.contre.2025.100084","DOIUrl":"10.1016/j.contre.2025.100084","url":null,"abstract":"<div><h3>Aims:</h3><div>To evaluate which parameters predicted the presence of detrusor overactivity after ATOMS implant in patients who had post prostatectomy urinary incontinence (PPI).</div></div><div><h3>Method:</h3><div>We carried out a prospective study in 56 patients submitted to ATOMS implant for PPI. The study consisted of a clinical and urodynamic record before and after ATOMS implantation. We built a multivariate model to find out which variables independently influenced postoperative DO and a ROC curve to decide the best cut-off value.</div></div><div><h3>Results:</h3><div>We found that the preoperative variables were age, detrusor pressure at maximum flow rate (PQmax) the urethral resistance parameter URA and the bladder contractility index (BCI) and the postoperative variables were, the number of ATOMS adjustments, cystometric bladder capacity, bladder compliance, maximum detrusor pressure, PQmax, bladder outflow obstruction index, URA and the presence of acontractile detrusor. The multivariate model showed that the only independent variables were age (inversely related with the presence of postoperative DO), and URA (directly related). The cut-off point of URA was established at 10. 5 cm H2O.</div></div><div><h3>Conclusions:</h3><div>the degree of postoperative resistance measured by the URA parameter and age were the two factors that independently influenced the presence of postoperative DO. It is possible that these parameters are related to the reaction of detrusor muscle to the increase in postoperative urethral resistance.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"14 ","pages":"Article 100084"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detrusor underactivity is the main reason for persistent symptoms after transurethral resection of the prostate 逼尿肌活动不足是经尿道前列腺切除术后症状持续的主要原因
Continence Reports Pub Date : 2025-05-13 DOI: 10.1016/j.contre.2025.100085
Esther Martinez-Cuenca, Miguel Á. Bonillo, Eduardo Morán, Salvador Arlandis
{"title":"Detrusor underactivity is the main reason for persistent symptoms after transurethral resection of the prostate","authors":"Esther Martinez-Cuenca,&nbsp;Miguel Á. Bonillo,&nbsp;Eduardo Morán,&nbsp;Salvador Arlandis","doi":"10.1016/j.contre.2025.100085","DOIUrl":"10.1016/j.contre.2025.100085","url":null,"abstract":"<div><h3>Introduction:</h3><div>Transurethral resection of the prostate has been considered the gold standard for surgical management of benign prostatic enlargement. Despite its high success rate, a percentage of patients (20%–40%) do not improve afterward. Our purpose is to determine the underlying lower urinary tract dysfunction of patients with persistent symptoms after transurethral resection of the prostate (TURP).</div></div><div><h3>Material and methods:</h3><div>We queried our prospectively maintained database to identify male patients with lack of symptoms improvement after TURP for benign condition. Patients with neurological condition and prostate cancer were excluded.</div><div>Evaluation included symptoms assessment, prostate volume, uroflowmetry, maximum cystometric capacity, bladder compliance, detrusor overactivity and urodynamic stress urinary incontinence. We considered obstruction if <em>Bladder Outlet Obstruction Index</em> (BOOI) <span><math><mo>≥</mo></math></span> 40, no obstruction if BOOI &lt; 20. We considered detrusor underactivity if <em>Bladder Contractility Index</em> (BCI) &lt; 100.</div></div><div><h3>Results:</h3><div>219 patients had complete urodynamic study. Complete data were obtained from 107 patients, the mean (SD) age was 65.6 (8.2) years. Median (IQR) prostatic volume was 40 (31)cc. After surgery, storage symptoms were the most prevalent (73.8% of the patients). Urodynamic findings were: detrusor underactivity in 75 of 107 patients (70.1%), detrusor overactivity in 54 (50.5%), obstruction in 26 (24.3%).</div><div>The only correlation found was between the pre-surgery voided volume in uroflowmetry and detrusor overactivity in the urodynamic study (rho: −0.28, p <span><math><mo>=</mo></math></span> 0.033). No difference regarding Qmax before and after TURP was observed in the detrusor underactivity group (p <span><math><mo>=</mo></math></span> 0.481). Unfavorable outcome after previous prostate surgery might be explained by detrusor underactivity rather than obstruction.</div></div><div><h3>Conclusions:</h3><div>The most common persistent symptoms after TURP are storage, and the most common urodynamic finding is detrusor underactivity. In this scenario urodynamic study is advisable.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"14 ","pages":"Article 100085"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144168704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Glucagon like Peptide-1 agonists on patients with overactive bladder: A pilot study 胰高血糖素样肽-1激动剂对膀胱过动症患者的影响:一项初步研究
Continence Reports Pub Date : 2025-05-13 DOI: 10.1016/j.contre.2025.100083
Max D. Sandler , Adam D. Williams , Alan Wein , Katherine Amin , Raveen Syan
{"title":"Effects of Glucagon like Peptide-1 agonists on patients with overactive bladder: A pilot study","authors":"Max D. Sandler ,&nbsp;Adam D. Williams ,&nbsp;Alan Wein ,&nbsp;Katherine Amin ,&nbsp;Raveen Syan","doi":"10.1016/j.contre.2025.100083","DOIUrl":"10.1016/j.contre.2025.100083","url":null,"abstract":"<div><h3>Purpose:</h3><div>To explore preliminary data on the subjective impact of Glucagon-Like Peptide-1 (GLP-1) agonists, commonly used for diabetes and obesity, on symptoms of overactive bladder (OAB), in order to guide future, larger-scale investigations.</div></div><div><h3>Methods:</h3><div>We distributed an anonymous survey on an online forum. Participants aged 18 or older who had used GLP-1 agonists and experienced OAB symptoms were eligible. We collected data on participants’ OAB symptoms, body weight changes, reasons for GLP-1 prescription, and demographics. Data was analyzed using SAS® software, with significance set at p &lt; 0.05.</div></div><div><h3>Results:</h3><div>Of 33 respondents, 27 identified as female and 6 male. All used semaglutide, primarily for weight loss (96.9%). Four had a urinary condition besides OAB. Eleven (33.3%) reported OAB symptom improvement after starting GLP-1 agonists with mean weight loss of 12.2%, but this was not significantly different from those with no change or worsening symptoms (8.4% and 10% mean weight loss, respectively; p = 0.24). Half of those with OAB episodes at least once daily experienced symptom improvement, compared to 7.7% with less frequent symptoms (p = 0.01). Of participants reporting symptom improvement, 90.91% experienced OAB daily (p = 0.01).</div></div><div><h3>Conclusion:</h3><div>While weight loss can improve OAB symptoms, the impact of GLP-1 agonists remains unclear. Our findings may suggest that those with more frequent OAB symptoms at baseline may derive greater benefit from GLP-1 agonists, offering a potential hypothesis for future investigation. Further studies are needed to explore how these medications impact management of OAB.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"14 ","pages":"Article 100083"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143948731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bladder wall abscess following surgical treatment of complicated diverticulitis: A case report 复杂性憩室炎手术后膀胱壁脓肿1例
Continence Reports Pub Date : 2025-05-12 DOI: 10.1016/j.contre.2025.100086
Narjes Sweis , John Smith , Patrick Bladek , Steven Garzon , Omer Acar , Gerald Gantt
{"title":"Bladder wall abscess following surgical treatment of complicated diverticulitis: A case report","authors":"Narjes Sweis ,&nbsp;John Smith ,&nbsp;Patrick Bladek ,&nbsp;Steven Garzon ,&nbsp;Omer Acar ,&nbsp;Gerald Gantt","doi":"10.1016/j.contre.2025.100086","DOIUrl":"10.1016/j.contre.2025.100086","url":null,"abstract":"<div><div>Bladder wall abscesses, though rare, pose significant diagnostic challenges due to their nonspecific presentation. This case presents a 47-year-old male with a history of complicated diverticulitis, who developed a bladder wall abscess following treatment for a colocutaneous fistula. Initial imaging showed bladder wall thickening, and the patient later presented with recurrent lower urinary tract symptoms and a fluid collection at the bladder dome. Despite negative urine cultures, antibiotic therapy, and no evidence of a colovesical fistula, the abscess recurred. The patient underwent cystoscopy and transurethral resection of the abscess. This minimally invasive approach was effective, and the patient had a full recovery with no further recurrence. This case emphasizes the need for timely evaluation and a broad differential diagnosis in patients with a history of diverticulitis and persistent bladder symptoms. It also adds valuable insights to the limited knowledge on managing rare bladder wall abscesses.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"14 ","pages":"Article 100086"},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144107212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacotherapy of bladder dysfunction — past, present and future 膀胱功能障碍的药物治疗-过去,现在和未来
Continence Reports Pub Date : 2025-04-25 DOI: 10.1016/j.contre.2025.100080
Karl-Erik Andersson
{"title":"Pharmacotherapy of bladder dysfunction — past, present and future","authors":"Karl-Erik Andersson","doi":"10.1016/j.contre.2025.100080","DOIUrl":"10.1016/j.contre.2025.100080","url":null,"abstract":"<div><div>Overactive bladder (OAB) encompasses a variety of conditions that may necessitate different therapeutic strategies. This diversity is evident in the wide range of medications used over the past five decades. Unfortunately, we have too few tools to identify individual conditions and even less information about which condition is best served by which treatment. Many of the drugs have been discontinued primarily due to an unfavorable balance between efficacy and adverse effects. As a result, current treatment guidelines primarily recommend antimuscarinics and <span><math><mi>β</mi></math></span>3-adrenoceptor agonists, with intravesical botulinum toxin injections as a second-line option. While these treatments have documented efficacy, their use is often limited by side effects, adherence challenges, and persistence issues. Personalized treatment approaches may help optimize the use of these medications. However, there is a need for improved therapies, and many promising future therapeutic alternatives can be discussed. However, there seem to be no drugs ready for immediate clinical introduction.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"14 ","pages":"Article 100080"},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy of the P-funnel, an external urinary collection device, for females in a hospital setting p -漏斗,一种体外尿液收集装置,对女性在医院设置的有效性
Continence Reports Pub Date : 2025-04-21 DOI: 10.1016/j.contre.2025.100082
Vania Chang (M.S.) , Joan M. Ching (R.N., D.N.P.) , Randal P. Ching (Ph.D.)
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