Continence Reports最新文献

{"title":"Pharmacotherapy of bladder dysfunction — past, present and future","authors":"Karl-Erik Andersson","doi":"10.1016/j.contre.2025.100080","DOIUrl":"10.1016/j.contre.2025.100080","url":null,"abstract":"<div><div>Overactive bladder (OAB) encompasses a variety of conditions that may necessitate different therapeutic strategies. This diversity is evident in the wide range of medications used over the past five decades. Unfortunately, we have too few tools to identify individual conditions and even less information about which condition is best served by which treatment. Many of the drugs have been discontinued primarily due to an unfavorable balance between efficacy and adverse effects. As a result, current treatment guidelines primarily recommend antimuscarinics and <span><math><mi>β</mi></math></span>3-adrenoceptor agonists, with intravesical botulinum toxin injections as a second-line option. While these treatments have documented efficacy, their use is often limited by side effects, adherence challenges, and persistence issues. Personalized treatment approaches may help optimize the use of these medications. However, there is a need for improved therapies, and many promising future therapeutic alternatives can be discussed. However, there seem to be no drugs ready for immediate clinical introduction.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"14 ","pages":"Article 100080"},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy of the P-funnel, an external urinary collection device, for females in a hospital setting","authors":"Vania Chang (M.S.) ,&nbsp;Joan M. Ching (R.N., D.N.P.) ,&nbsp;Randal P. Ching (Ph.D.)","doi":"10.1016/j.contre.2025.100082","DOIUrl":"10.1016/j.contre.2025.100082","url":null,"abstract":"<div><div><strong>Objectives</strong>: For females with limited mobility, toileting can be challenging, and effective options that foster independence and continence are few. This study examines the usability and effectiveness of the P-funnel^TM, a new external urinary collection device for females with mobility challenges, and postulates its potential for increasing independence, reducing risks for infection and skin breakdown, and sustaining continence.</div><div><strong>Study Design</strong>: Prospective, single-center, survey study of hospitalized female volunteers.</div><div><strong>Methods</strong>: Fourteen hospitalized female patients who met the eligibility criteria were enrolled in this study. Each participant was trained on the use of the P-funnel, performed at least one supine void, then completed a 5-point Likert questionnaire. The survey questions focused on comfort, ease of use, and functionality.</div><div><strong>Results</strong>: The participant’s average satisfaction rating across the 10 question survey was 4.37 out of 5. For overall comfort, 85.8% of the participants scored the P-funnel as 4 or higher (out of 5). For questions concerning ease of use, 92.9% agreed the device was easy to position, and 85.8% agreed it was not difficult to hold the funnel in place while peeing. While 42.9% of the participants did encounter some leakage during use, 90.9% felt the P-funnel was easier to use than what they were currently using and 100% agreed that they would able to use the device confidently and would recommend it to others.</div><div><strong>Conclusions</strong>: Overall the P-funnel functioned well with generally high satisfaction scores for ease of use and comfort. And, for females with ambulatory difficulty, it has the potential to increase independence and reduce the hazards associated with toileting.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"14 ","pages":"Article 100082"},"PeriodicalIF":0.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary continence outcomes during the transition from laparoscopic to robotic assisted radical prostatectomy: A single surgeon’s Australian regional centre experience","authors":"Basil Razi ,&nbsp;Dane Cole-Clark ,&nbsp;Duncan Self ,&nbsp;Mark Louie-Johnsun","doi":"10.1016/j.contre.2025.100079","DOIUrl":"10.1016/j.contre.2025.100079","url":null,"abstract":"<div><h3>Introduction &amp; Objectives:</h3><div>Robotic assisted laparoscopic radical prostatectomy (RARP) is becoming standard of care for prostate cancer patients requiring surgical intervention. Postoperative continence significantly impacts patients’ quality of life, making functional outcomes a critical focus in the evolution of surgical techniques. Alternative methods, including open and laparoscopic techniques, have been superseded with increased availability of robotic units within Australia. This study aims to review an experienced laparoscopic surgeon’s transition to robotic prostatectomy and the impact on continence.</div></div><div><h3>Methods:</h3><div>Prospective data collection included patient demographics, surgical method, and pad usage at 3 and 12 months postoperatively. The final 100 laparoscopic radical prostatectomy (LRP) cases (May 2019–August 2021) were compared with the first 100 RARP cases (August 2021–February 2023), all performed by the same surgeon. Continence rates were assessed using patient-reported pad usage.</div></div><div><h3>Results:</h3><div>The mean age was similar between LRP (65.3 years) and RARP (65.4 years) groups. Continence rates at 3 and 12 months were 67.0% and 90.4% for LRP patients versus 78% and 94% for RARP patients. Odds ratio analysis indicated LRP patients were 1.75 and 1.66 times more likely to be incontinent at 3 and 12 months, respectively.</div></div><div><h3>Conclusion:</h3><div>RARP demonstrated higher continence rates without evidence of a learning curve during the transition from LRP. These findings underscore the potential for improved patient outcomes with wider adoption of robotic systems in Australia.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"14 ","pages":"Article 100079"},"PeriodicalIF":0.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transvaginal mechanotherapy for stress urinary incontinence: Principles, cellular and neuromuscular mechanisms of action, and comparison to current gold standard treatments","authors":"Alisha Fulker ,&nbsp;Shravya Kovela ,&nbsp;Marcus Mianulli","doi":"10.1016/j.contre.2024.100077","DOIUrl":"10.1016/j.contre.2024.100077","url":null,"abstract":"<div><div>Mechanotransduction is a scientific principle by which cells sense and respond to mechanical stimuli. Mechanotherapy is the clinical application of mechanotransduction for tissue repair in muscle rehabilitation. Pelvic floor muscle training (PFMT) is currently the conservative gold standard of care for treatment of women with stress urinary incontinence (SUI). Mechanotherapy can increase the effectiveness of PFMT, especially when applied intravaginally for a direct transvaginal treatment to the pelvic floor muscles. With an understanding of the benefits of mechanotherapy, its mechanisms of action, and the resulting neuromuscular recruitment leading to the long-term durability of continence results, transvaginal mechanotherapy has the potential to become a complimentary first-line standard of care for women with SUI.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"13 ","pages":"Article 100077"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravesical migration of intrauterine device: Case report and literature review","authors":"Gamal M. Ghoniem ,&nbsp;Tivoli Nguyen","doi":"10.1016/j.contre.2024.100074","DOIUrl":"10.1016/j.contre.2024.100074","url":null,"abstract":"<div><div>Intrauterine devices are a commonly used method of female contraception that has become increasingly popular worldwide because they are highly effective and convenient to use. However, complications, such as migration to nearby viscera or peritoneal cavity, can occur. The bladder is an especially uncommon destination for migration. Here, we report a rare case of IUD intravesical migration in a 30-year-old female patient presenting with lower abdominal pain and menorrhagia who had an IUD placed 8 years prior.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"12 ","pages":"Article 100074"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of videourodynamics, imaging, and cystoscopy in patients with recurrent urinary tract infections: Should we throw in the kitchen sink?","authors":"G. Chan ,&nbsp;F. Davidovic ,&nbsp;J. Gani","doi":"10.1016/j.contre.2024.100073","DOIUrl":"10.1016/j.contre.2024.100073","url":null,"abstract":"<div><h3>Purpose:</h3><div>Recurrent urinary tract infection (rUTI) remains a common outpatient problem with discordance and paucity of evidence for management. This study aims to evaluate the role of videourodynamics (VUD), additional imaging, and cystoscopy in the complete workup of these patients.</div></div><div><h3>Materials and Methods:</h3><div>A retrospective review was performed on 1421 consecutive patients referred for physician performed VUD. After exclusion criteria, 170 patients were included. Ethics approval was obtained, followed by data collection, and analysis of demographics, symptoms, cystoscopy results, imaging, and VUD parameters. Statistical analyses were performed with IBM SPSS Statistics Version 28. Statistical significance was defined by an alpha level of P <span><math><mrow><mo>≤</mo><mn>0</mn><mo>.</mo><mn>05</mn></mrow></math></span>.</div></div><div><h3>Results:</h3><div>Overall, 117/170 (69%) had identifiable causes of rUTI identified on VUD. There was a statistically significant difference (<em>p</em>&lt;0.001) in identifying a cause in those with voiding symptoms (93/114 <span><math><mo>=</mo></math></span> 82%) compared to those without (24/56 <span><math><mo>=</mo></math></span> 43%). Gender was not predictive of an identifiable cause on VUD (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>47</mn></mrow></math></span>). Neither was a neurogenic history (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>11</mn></mrow></math></span>), diabetes (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>97</mn></mrow></math></span>), or age (<span><math><mrow><mi>p</mi><mo>=</mo><mn>0</mn><mo>.</mo><mn>89</mn></mrow></math></span>). Additional imaging was not diagnostic for rUTI cause. No malignancy was identified on imaging or cystoscopy.</div></div><div><h3>Conclusion:</h3><div>In patients with rUTI, VUD may be an important investigative step to find a possible underlying cause, but it is a scarce resource. As VUD has a higher detection rate in patients with voiding symptoms, by first screening for these patients on history, VUD can be used judiciously. Cystoscopy and additional imaging were not as helpful in identifying a target treatment plan for rUTI, when a VUD had already been done.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"12 ","pages":"Article 100073"},"PeriodicalIF":0.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142662507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of artificial urinary sphincter versus male slings in treatment of male urinary incontinence: Systematic review and meta-analysis","authors":"Bagrat Grigoryan ,&nbsp;George Kasyan ,&nbsp;Roman Shapovalenko ,&nbsp;Dmitry Pushkar","doi":"10.1016/j.contre.2024.100070","DOIUrl":"10.1016/j.contre.2024.100070","url":null,"abstract":"<div><h3>Background and objective:</h3><div>Male stress urinary incontinence (UI) remains a serious problem associated with a significant quality of life reduction. The aim of this study is to determine the safety and effectiveness of artificial urinary sphincter (AUS) and male slings (MS) for stress UI in men.</div></div><div><h3>Evidence acquisition:</h3><div>Inclusion criteria: randomized/non-randomized trials evaluating adult men with stress UI. Exclusion criteria: repeated SUI surgery, combined conservative interventions and pharmacological treatment. The electronic databases were searched up to January 2024. The systematic review was conducted according to PICO framework and PRISMA 2020 guidelines and was registered in PROSPERO. The risk of bias was evaluated using the tools recommended by the Cochrane Society.</div></div><div><h3>Evidence synthesis:</h3><div>Thirteen clinical trials were included in the systematic review, and 11 in the meta-analysis. There was no statistically significant difference in the improvement rate between AUS and MS (RR <span><math><mo>=</mo></math></span> 0.93, 95% CI: [0.85, 1.02], p<span><math><mo>=</mo></math></span> 0.13). MS showed statistically significant fewer infectious complication (RR <span><math><mo>=</mo></math></span> 3.26, 95% CI: [1.97, 5.39], p&lt;0.00001), device explantation (RR <span><math><mo>=</mo></math></span> 3.29, 95% CI: [2.46, 4.41], p&lt;0.00001), surgical revision (RR <span><math><mo>=</mo></math></span> 2.27, 95% CI: [1.60, 3.20], p&lt;0.00001), urinary retention (RR <span><math><mo>=</mo></math></span> 0.04, 95% CI: [0.01, 0.07], p <span><math><mo>=</mo></math></span> 0.004) rates and operation time (RR <span><math><mo>=</mo></math></span> 0.93, 95% CI: [0.85, 1.02], p <span><math><mo>=</mo></math></span> 0.13) compared with AUS.</div></div><div><h3>Conclusion:</h3><div>AUS demonstrates a comparable improvement level to MS. The operation time, infectious complication, device explantation, urinary retention, and surgical revision rates were lower in MS. More randomized and prospective studies with long-term follow-up will further increase confidence in the choice between AUS and MS for male UI treatment.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"12 ","pages":"Article 100070"},"PeriodicalIF":0.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142662508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful management of high urogenital sinus in an adult female: Case report","authors":"Gamal Ghoniem ,&nbsp;Nardeen Magdy Samaan ,&nbsp;Mohamed Samir ,&nbsp;Muhammed A. Moukhtar Hammad ,&nbsp;Ashraf G. Fahmy","doi":"10.1016/j.contre.2024.100068","DOIUrl":"10.1016/j.contre.2024.100068","url":null,"abstract":"<div><div>This case report presents the successful management of high urogenital sinus (UGS) in a 21-year-old female using a modified Anterior Sagittal Transrectal Approach (ASTRA). The patient, with a history of painful cyclic hematuria and delayed menarche, was initially misdiagnosed with a transverse vaginal septum. Diagnostic clarity was achieved through cystourethroscopy, revealing a single external meatal opening indicative of UGS. The modified ASTRA technique, including a rectum-sparing approach, was employed to correct the anomaly. Preoperative administration of leuprolide acetate helped reduce the risk of postoperative infections and complications. Postoperative care included serial vaginal dilatations to prevent stenosis, resulting in no complications or need for further surgical interventions at 12-month follow-up. This case highlights the importance of a multidisciplinary approach and the potential of the modified ASTRA technique in managing high UGS in adult patients. Further research to validate these findings in a larger cohort could be difficult because of rarity to miss the diagnosis in adult females.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"12 ","pages":"Article 100068"},"PeriodicalIF":0.0,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"History of urodynamics. Its origins, development and implication for urology as a specialty in Europe and the USA","authors":"Friedrich H. Moll ,&nbsp;Thorsten Halling ,&nbsp;Werner Schäfer","doi":"10.1016/j.contre.2024.100069","DOIUrl":"10.1016/j.contre.2024.100069","url":null,"abstract":"<div><div>The field of urodynamics playes a major role in the development of urology as a specialty. It was the corner stone in functional thinking and a major point in establishing a science of its own, because physiological aspects payed the major role in generating new theories. This was in contrast to surgery. Within this field of medicine it needs up to the 1970th and 1980th establishing a functional view on aspects of treating diseases at all. Up to this time here, knife had the first place.</div><div>A part of this topic regarding aspects of the German speaking countries had just been published Moll F. Halling T Geschichte der Urodynamik in: Schultz-Lampel, D., Goepel, M., Hampel, C. (eds) Urodynamik. Springer, Berlin, Heidelberg. 2022 pp 3-22 <span><span>https://doi.org/10.1007/978-3-662-59066-9_1</span><svg><path></path></svg></span> p 2-22.</div><div>Moll, F. 2001 Historische Anmerkungen zur Entwicklung der Neuro-Urologie in: Nissen G., Badura F. (Hrsg) Schriftenreihe der Deutschen Gesellschaft für Geschichte der Nervenheilkunde, Band 7. Königshausen und Neumann Würzburg 2001.</div></div>","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"12 ","pages":"Article 100069"},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142662558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to: “Can recurrent UTIs in women be cured? Review article” [Cont. Rep. 5 (2023) 100021]","authors":"Valeerat Swatesutipun","doi":"10.1016/j.contre.2024.100067","DOIUrl":"10.1016/j.contre.2024.100067","url":null,"abstract":"","PeriodicalId":100330,"journal":{"name":"Continence Reports","volume":"12 ","pages":"Article 100067"},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}