Cochrane Evidence Synthesis and Methods最新文献

{"title":"Single-arm interventional versus observational studies for assessing efficacy: A meta-epidemiological study","authors":"Mary Chappell,&nbsp;Deborah Watkins,&nbsp;Alice Sanderson,&nbsp;Lavinia Ferrante di Ruffano,&nbsp;Paul Miller,&nbsp;Hariet Fewster,&nbsp;Anita Fitzgerald,&nbsp;Mary Edwards,&nbsp;Rachael McCool","doi":"10.1002/cesm.70016","DOIUrl":"https://doi.org/10.1002/cesm.70016","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Interventional single-arm trials (SATs) are increasingly being used as evidence, despite a lack of agreement on their validity and where they should sit in the hierarchy of evidence. We conducted a meta-epidemiological study to investigate whether there are systematic differences in outcomes and levels of between-study heterogeneity for SATs compared with their observational counterpart, single-arm cohort studies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We identified systematic reviews (SRs) of pharmacological interventions, published in 2023, that included both interventional and observational single-arm studies. For each SR, subgroup meta-analysis of dichotomous outcomes was conducted for included SATs and single-arm cohort studies to assess effect sizes, levels of heterogeneity and between group differences. In a sensitivity analysis, clinically heterogeneous primary studies were removed and analyses re-run.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>66 SRs contained single-arm studies, of which 13 reported meta-analyses of dichotomous efficacy outcomes. There was no overall risk difference for SATs compared with single-arm cohort studies (risk difference: −0.020, 95% CI: −0.092 to 0.052, <i>p</i> = 0.59). In the sensitivity analysis, there was a tendency to higher effect for single-arm cohort studies, but no significant difference (risk difference: −0.071, 95% CI: −0.161, 0.019, <i>p</i> = 0.12). There were high levels of between-study heterogeneity within both SATs (median; range <i>I</i>²: 54.8; 11.3–91.0) and single-arm cohorts (median; range <i>I</i>²: 77.2; 0–94.7) and heterogeneity remained high in the sensitivity analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>There do not appear to be systematic differences in outcome between SATs and single-arm cohort studies, but further research is recommended to confirm this finding. Levels of heterogeneity are high within both designs, even after attempts to reduce clinical heterogeneity. Because clinical heterogeneity had potentially been removed, remaining statistical heterogeneity may have been due to bias related to study conduct. Future work should utilize larger samples and additional methods to further clarify the relative validity of single-arm designs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100286,"journal":{"name":"Cochrane Evidence Synthesis and Methods","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cesm.70016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143115215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can using the Cochrane RCT classifier in EPPI-Reviewer help speed up study selection in qualitative evidence syntheses? A retrospective evaluation","authors":"Heather Melanie R. Ames,&nbsp;Christine Hillestad Hestevik,&nbsp;Patricia Sofia Jacobsen Jardim,&nbsp;Martin Smådal Larsen,&nbsp;Lars Jørun Langøien,&nbsp;Hans Bugge Bergsund,&nbsp;Tiril Cecilie Borge","doi":"10.1002/cesm.70012","DOIUrl":"https://doi.org/10.1002/cesm.70012","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Using machine learning functions, such as study design classifiers, to automatically identify studies that do not meet the inclusion criteria, is one way to speed up the systematic review screening process. As a qualitative study design classifier is yet to be developed, using the Cochrane randomized controlled trial (RCT) classifier in reverse is one possible way to speed up the identification of primary qualitative studies during screening. The objective of this study was to evaluate whether the Cochrane RCT classifier can be used to speed up the study selection process for qualitative evidence synthesis (QES).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We performed a retrospective evaluation where we first identified QES. We then extracted the bibliographic information of the included primary qualitative studies in each QES, and uploaded the references into our data management tool, EPPI-Reviewer. We then ran the Cochrane RCT classifier on each group of included studies for each QES.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Eighty-two QES with 2828 unique primary studies were included in the analysis. 56% of the primary studies were classified as unlikely to be an RCT and 40% as being 0–9% likely to be an RCT. 4% were classified as being 10% or more likely to be an RCT. Of these, only 1.7% were classified as being 50% or more likely to be an RCT.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The Cochrane RCT classifier could be a useful tool to identify primary studies with qualitative study designs to speed up study selection in a QES. However, it is possible that mixed methods studies or qualitative studies conducted as part of a clinical trial may be missed. Further evaluations using the Cochrane RCT classifier on all the references retrieved from the complete literature search is needed to investigate time- and resource savings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100286,"journal":{"name":"Cochrane Evidence Synthesis and Methods","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cesm.70012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143114777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inclusion, characteristics and methodological limitations of systematic reviews in doctoral theses: A cross-sectional study of all universities in Sweden","authors":"M. Ringsten,&nbsp;K. Färnqvist,&nbsp;M. Bruschettini,&nbsp;M. Johansson","doi":"10.1002/cesm.70015","DOIUrl":"https://doi.org/10.1002/cesm.70015","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Intro</h3>\u0000 \u0000 <p>A systematic review (SR) attempts to find, assess and summarize all the empirical evidence to answer a specific research question. We aim to explore to what extent reviews are included in doctoral theses from all universities with a medical faculty in Sweden, and to describe the type, topic and assess the methodological quality of the reviews.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Duplicate assessors independently searched local and national repositories for doctoral theses published in 2021 within all seven medical faculties in Sweden, and categorized identified reviews based on review type, topic, and methodological quality using AMSTAR-2.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>5.4% (45/852) of all doctoral theses included a review, and 1.3% (45/3461) of all included studies were reviews. Of these, two thirds (31) were SRs and the rest (14) were broader ‘big picture’ reviews. The most common topics were interventions (42%) and exposure/etiology (32%), with no reviews of diagnostic tests. The majority of the SRs had very low (71%) or low (19%) quality, and few reached a high (7%) or moderate (3%) quality. The most common issues were limitations with protocols, limited search strategies, and failure to account for risk of bias in drawn conclusions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Few doctoral students included SRs in their theses, and the few SRs included in doctoral theses generally had a low quality. There is no consensus on the appropriate proportion of doctoral thesis including a SR. We argue that conducting a SR within a doctoral thesis can reduce redundant, harmful and unethical research, identify knowledge gaps, and help the doctoral student obtain important skills to conduct and use research.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100286,"journal":{"name":"Cochrane Evidence Synthesis and Methods","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cesm.70015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143113480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using visual methods to further enhance qualitative evidence synthesis","authors":"Mayara Silveira Bianchim,&nbsp;Emma F. France,&nbsp;Jane Noyes","doi":"10.1002/cesm.70009","DOIUrl":"10.1002/cesm.70009","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The use of visual methods in qualitative evidence synthesis (QES) adds a valuable dimension to the synthesis process by enhancing understanding and knowledge generation. Visual methods are currently underused and underreported in QES.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This is the first study to describe accessible visual methods that support various stages of QES and to show the application of visual methods to a Cochrane QES of 43 studies using meta-ethnography and systematic review methods. This study also addresses the involvement of stakeholders including the public, practical considerations of equity, diversity, inclusion, and reflexivity in the selection and application of visual methods.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In a novel approach, the review authors utilized a combination of remote and in-person visual methods to initiate and develop their synthesis, involving stakeholders throughout the process. The review authors used methods including paper labels, cartoons, infographics, virtual whiteboards, and diagrams. The rigorous use of visual methods in the QES facilitated data visualization, remote analysis meetings, interpretation of extensive data, and meaningful patient and public involvement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>QES authors are encouraged to consider the use of visual methods, particularly when involving the public in the synthesis process. When selecting visual methods, authors should consider how they align with the study's objectives, suit the stage of synthesis, might enhance analysis, their available resources, and the team's technical skills.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100286,"journal":{"name":"Cochrane Evidence Synthesis and Methods","volume":"2 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142934240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Cochrane systematic reviews: A comprehensive study of impact and influence from 1998 to 2024","authors":"Amin Sharifan","doi":"10.1002/cesm.70010","DOIUrl":"https://doi.org/10.1002/cesm.70010","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Evidence from Cochrane systematic reviews has significantly impacted clinical practices across diverse disciplines and is widely integrated into international guidelines. To date, there are no bibliometric analyses of Cochrane's publications.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The search encompassed the Scopus database from inception to May 2024, with results limited to studies published by the Cochrane Database of Systematic Reviews. The analysis examined annual trends and publication volumes, citation patterns, contributing countries, authors, institutions, funding sources, and common keywords. Scopus' built-in analytical tools, the bibliometrix package in RStudio, and VOSviewer software facilitated the analysis of the results.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 12,150 systematic reviews were eligible. There was a fluctuating pattern in publication and citation trends within Cochrane reviews, with a decline in both metrics since 2016. Contributions mainly came from high-income countries, their institutions, and authors residing there, with significant government funding supporting publications in these regions. The United Kingdom (27%), Australia (10%), and the United States (9%) had the greatest contributions among other countries, respectively. Furthermore, the demographic emphasis in Cochrane reviews was concerned with female and male participants as well as children and adult populations, hinting at the potential underrepresentation of minor gender identities and older adults in the synthesis of evidence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Cochrane should actively involve researchers and experts from low- and middle-income countries in evidence synthesis, ensure underrepresented and low-resource regions are included in its emerging Evidence Synthesis Units and Thematic Groups, and prioritize the inclusion of geriatric populations and sexual and gender minorities in its evidence to enhance inclusivity and global representation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100286,"journal":{"name":"Cochrane Evidence Synthesis and Methods","volume":"2 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cesm.70010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodological and reporting quality of systematic and rapid reviews on human mpox and their utility during a public health emergency","authors":"Kusala Pussegoda,&nbsp;Izza Israr,&nbsp;Austyn Baumeister,&nbsp;Tricia Corrin,&nbsp;Melanie Sterian,&nbsp;Mavra Qamar,&nbsp;Anmol Samra,&nbsp;Lisa Waddell","doi":"10.1002/cesm.70005","DOIUrl":"https://doi.org/10.1002/cesm.70005","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Evidence syntheses were rapidly produced during the 2022 mpox outbreak despite a lack of studies. The aim of this methodological study was to assess the quality and utility of the evidence syntheses produced during the first 6 months of the outbreak compared to those published before it.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Human mpox evidence syntheses available before December 31, 2022 were retrieved from PubMed, Scopus, EuropePMC, SSRN, and arXiv. Study characteristics, utility, methodological, and reporting quality (AMSTAR-2 and PRISMA) were contrasted between syntheses produced before the 2022 outbreak (historical) and during the first 6 months (new). Results were synthesized narratively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-six evidence syntheses were included; two historical systematic reviews (SRs) and 24 new SRs, rapid reviews, scoping reviews, and mislabelled syntheses. Median time from search to publication/preprint post date was 68 and 6 weeks for historical and new syntheses, respectively. Among the new syntheses, 8% (2/24) did not include evidence from the 2022 outbreak, 33% (8/24) included only new evidence and 58% (14/24) included both new and historical evidence. Only 29% of new syntheses contrasted findings between new and historical evidence. Methodological quality was critically low for 100% of historical syntheses and 92% of new syntheses and the remainder (8%) were low. Reporting quality was poor with a median of 10.5 (range 10–11) and 11.5 (range 4–21) of 27 items reported sufficiently by historical and new syntheses, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Evidence syntheses take time to produce and during an emergent outbreak they are often outdated at the time of publication and suffer from poor adherence to methodological and reporting guidelines. Overlapping content and few new studies resulted in minimal added value to the mpox literature. Strategies to reduce duplication and mechanisms to produce and disseminate continuously updated living evidence syntheses need to be explored to support decision-makers responding to an emergency.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100286,"journal":{"name":"Cochrane Evidence Synthesis and Methods","volume":"2 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cesm.70005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Interest-holders”: A new term to replace “stakeholders” in the context of health research and policy","authors":"Elie A. Akl,&nbsp;Joanne Khabsa,&nbsp;Jennifer Petkovic,&nbsp;Olivia Magwood,&nbsp;Lyubov Lytvyn,&nbsp;Ashley Motilall,&nbsp;Pauline Campbell,&nbsp;Alex Todhunter-Brown,&nbsp;Holger J. Schünemann,&nbsp;Vivian Welch,&nbsp;Peter Tugwell,&nbsp;Thomas W. Concannon","doi":"10.1002/cesm.70007","DOIUrl":"https://doi.org/10.1002/cesm.70007","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Given the colonial connotations of the term “stakeholder”, its continued use may be perceived as disrespectful to Indigenous Peoples. While several groups have introduced alternative terms, each has its own limitations. The objective of this article is to introduce “interest-holders” as an alternative term to “stakeholders” and describe the discussions underpinning the adoption of the new term by the MuSE Consortium.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The MuSE Consortium is an international network of over 160 individuals with interest and expertise in different aspects relevant to engagement in research. Members of MuSE explored alternative terms and considered their respective merits and limitations. The deliberations considered the literature on the topic and the results of two consultations with the wider MuSE membership on the alternative terms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We define “interest-holders” as groups with legitimate interests in the health issue under consideration. The interests arise and draw their legitimacy from the fact that people from these groups are responsible for or affected by health-related decisions that can be informed by research evidence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>As groups other than the MuSE Consortium have started to adopt “interest-holders,” we hope its use will reduce confusion related to the multitude of terms used and convey the intended meaning without any negative connotations.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100286,"journal":{"name":"Cochrane Evidence Synthesis and Methods","volume":"2 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cesm.70007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142555419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Empowering the future of evidence-based healthcare: The Cochrane Early Career Professionals Network","authors":"Ana Beatriz Pizarro,&nbsp;Santiago Castiello-de Obeso,&nbsp;Ahmad Sofi-Mahmudi,&nbsp;Robin Vernooij,&nbsp;Elpida Vounzoulaki,&nbsp;Chris Champion","doi":"10.1002/cesm.70006","DOIUrl":"https://doi.org/10.1002/cesm.70006","url":null,"abstract":"&lt;p&gt;The Cochrane Early Career Professionals Network (ECPN) is a diverse global network of emerging volunteer health professionals committed to advancing evidence-based healthcare worldwide [&lt;span&gt;1&lt;/span&gt;]. Established in September 2019 by Robin Vernooij and Chris Champion, the ECPN was inspired by similar early career researcher groups in scientific associations. Cochrane received many inquiries from young researchers eager to engage with the activities, highlighting a growing demand for such a network.&lt;/p&gt;&lt;p&gt;Cochrane's contributors come from varied backgrounds and cultures, including researchers, health sciences students, language translators, and other volunteers, all united in their commitment to supporting global healthcare initiatives [&lt;span&gt;2&lt;/span&gt;]. In line with Cochrane's mission to highlight the contributions of the next generation, Cochrane launched the “30 Under 30” initiative, inviting 30 young researchers with diverse professional backgrounds such as nurses, doctors, dentists, physiotherapists, biologists, psychologists, and journalists to join the series and tell their Cochrane Story. To build on the success of this initiative, Vernooij proposed formalizing this group into a network, which was well received as the idea aligned perfectly with the Cochrane membership strategy. Consequently, all participants in the “30 Under 30” series were invited to become the first members of the ECPN [&lt;span&gt;2&lt;/span&gt;]. The ECPN was due to be launched in Santiago, Chile at the 2019 Cochrane Colloquium, themed “Embracing Diversity,” but due to the cancellation of the event, it was ultimately launched online later in 2019.&lt;/p&gt;&lt;p&gt;The ECPN now plays a crucial role in promoting professional development, international networking, collaboration, and leadership within the Cochrane community, ensuring that the voices of early career professionals (ECP) are heard, and their potential maximized [&lt;span&gt;1&lt;/span&gt;]. The objective of this commentary is to provide a comprehensive overview of the ECPN in Cochrane, with the aim of raising awareness and enhancing the visibility of the network within the Cochrane and scientific community.&lt;/p&gt;&lt;p&gt;The ECPN is focused on expanding our international network and fostering closer collaboration with other groups, such as the Campbell Collaboration, the Joanna Briggs Institute, Sense about Science, and the Cochrane US mentoring program [&lt;span&gt;3&lt;/span&gt;]. We actively explore new ways to involve individuals at the early stages of their careers in research, including students, and young professionals in our research and projects, ensuring their perspectives are integrated into our work. Additionally, we are working on innovative approaches to knowledge translation, aiming to make Cochrane reviews more accessible and impactful. The network consists of a steering group, led by a Chair, that supports the early career professionals' community. We currently have 15 active members, and over the 5 years since the network's founding, a tota","PeriodicalId":100286,"journal":{"name":"Cochrane Evidence Synthesis and Methods","volume":"2 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cesm.70006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142524903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing interactive evidence maps: Visualising service commissioning options alongside research","authors":"Helen Burchett,&nbsp;Claire Stansfield,&nbsp;Wendy Macdowall,&nbsp;Michelle Richardson,&nbsp;Samantha Dick,&nbsp;Kelly Dickson,&nbsp;Preethy D'Souza,&nbsp;Claire Khouja,&nbsp;Irene Kwan,&nbsp;Gary Raine,&nbsp;Amanda Sowden,&nbsp;Katy Sutcliffe,&nbsp;James Thomas","doi":"10.1002/cesm.70003","DOIUrl":"https://doi.org/10.1002/cesm.70003","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Interactive evidence maps typically visualise characteristics of research evidence, and gaps in evidence, in a particular field.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims, Materials &amp; Methods</h3>\u0000 \u0000 <p>Here we present an example of an evidence map on digital drug and alcohol interventions in which the research evidence is supplemented with information about interventions in use (or available for use) in England. We used systematic review methods to identify systematic reviews of intervention effectiveness and an online survey to identify interventions in England.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Eighteen reviews and 40 interventions were included in the online map.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion &amp; Conclusion</h3>\u0000 \u0000 <p>To our knowledge, this is the first map to juxtapose research and practice in this way. By extending evidence maps to include data on service provision, it becomes easier to see whether research and practice are aligned and where gaps in either evidence or practice (or both) exist.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100286,"journal":{"name":"Cochrane Evidence Synthesis and Methods","volume":"2 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cesm.70003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142438895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The new rehabilitation definition for research purposes could improve rehabilitation description in Cochrane Systematic Reviews","authors":"Irene Battel,&nbsp;Chiara Arienti,&nbsp;William Levack,&nbsp;Carlotte Kiekens,&nbsp;Stefano Negrini","doi":"10.1002/cesm.70000","DOIUrl":"https://doi.org/10.1002/cesm.70000","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Introduction&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;In 2022, Cochrane Rehabilitation developed a new definition of rehabilitation for research purposes with 80 global stakeholders, aiming to support and improve the production and reporting of primary and evidence-synthesis rehabilitation studies.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objective&lt;/h3&gt;\u0000 \u0000 &lt;div&gt;\u0000 \u0000 &lt;ul&gt;\u0000 \u0000 &lt;li&gt;&lt;span&gt;1. &lt;/span&gt;\u0000 \u0000 &lt;p&gt;To compare how Cochrane Systematic Review (CSR) authors describe rehabilitation interventions against criteria derived from the new rehabilitation definition.&lt;/p&gt;\u0000 &lt;/li&gt;\u0000 \u0000 &lt;li&gt;&lt;span&gt;2. &lt;/span&gt;\u0000 \u0000 &lt;p&gt;To assess limitations or gaps in the rehabilitation definition.&lt;/p&gt;\u0000 &lt;/li&gt;\u0000 &lt;/ul&gt;\u0000 &lt;/div&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;We analysed a sample of 124 randomly selected CSRs tagged in the Cochrane Rehabilitation database. We converted the Cochrane Rehabilitation definition for research purposes into a set of 13 criteria grouped according to the four PICO elements and searched for the corresponding key elements in each CSR. We verified if and where in the review these elements were present. Two reviewers rated each CSR, resolving disagreements with a third author when needed. We analysed the findings using descriptive statistics.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Eight (6.5%) of 124 CSRs met all rehabilitation definition criteria. These were CSRs that investigated the effects of complex rehabilitation interventions. Three (2.4%) CSRs did not meet any PICO elements. Overall, the “Intervention-General” element and disability criterion had the highest prevalence of absent and unclear reporting, while the “Intervention-Specific” and “Outcome” elements were most frequently reported, albeit not in the “Description of the intervention” section of the review.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Discussion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This study showed that the key elements of the new rehabilitation definition are almost always reported in publications identified as rehabilitation reviews but not always consistently or clearly. The disability criterion was frequently unreported, given that the main aim of rehabilitation is reducing disability. Also, the main elements of rehabilitation were frequently not reported. We did not f","PeriodicalId":100286,"journal":{"name":"Cochrane Evidence Synthesis and Methods","volume":"2 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cesm.70000","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142174276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}