CJC Pediatric and Congenital Heart Disease最新文献

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Considerations in Timing of Surgical Repair in Tetralogy of Fallot 法洛四联症手术修复时机的考虑
CJC Pediatric and Congenital Heart Disease Pub Date : 2023-12-01 DOI: 10.1016/j.cjcpc.2023.10.006
Alqasem Al Mosa MD , Pierre-Luc Bernier MD, MPH, FRCSC , Christo I. Tchervenkov MD, FRCSC
{"title":"Considerations in Timing of Surgical Repair in Tetralogy of Fallot","authors":"Alqasem Al Mosa MD ,&nbsp;Pierre-Luc Bernier MD, MPH, FRCSC ,&nbsp;Christo I. Tchervenkov MD, FRCSC","doi":"10.1016/j.cjcpc.2023.10.006","DOIUrl":"10.1016/j.cjcpc.2023.10.006","url":null,"abstract":"<div><p>Certain aspects of the treatment of tetralogy of Fallot (TOF) repair remain controversial. The optimal timing of the elective repair of asymptomatic patients and the ideal strategy for managing symptomatic neonates and infants with TOF are still debated despite years of experience in TOF treatment. In this article, we discuss why a surgical correction at 3-6 months of age is likely the ideal time frame for the elective repair of TOF. We also elaborate on our strategy for managing symptomatic neonates and infants with TOF and why we prefer an early single-stage primary repair.</p></div>","PeriodicalId":100249,"journal":{"name":"CJC Pediatric and Congenital Heart Disease","volume":"2 6","pages":"Pages 361-367"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772812923001574/pdfft?md5=2d2db1b253e8887a918b62a369049a34&pid=1-s2.0-S2772812923001574-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135809578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Catheter-based Interventions in Tetralogy of Fallot Across the Lifespan 终身法洛四联症的导管干预
CJC Pediatric and Congenital Heart Disease Pub Date : 2023-12-01 DOI: 10.1016/j.cjcpc.2023.09.005
Ningyan Wong MBBS , Michael Shorofsky MD , D. Scott Lim MD
{"title":"Catheter-based Interventions in Tetralogy of Fallot Across the Lifespan","authors":"Ningyan Wong MBBS ,&nbsp;Michael Shorofsky MD ,&nbsp;D. Scott Lim MD","doi":"10.1016/j.cjcpc.2023.09.005","DOIUrl":"10.1016/j.cjcpc.2023.09.005","url":null,"abstract":"<div><p>Surgical treatment of tetralogy of Fallot (TOF) involves surgical relief of right ventricular outflow tract (RVOT) obstruction and closure of ventricular septal defect. However, some patients may require staged palliation before surgical repair. This traditionally was achieved only with surgery but recently evolved to include catheter-based techniques. RVOT dysfunction occurs inevitably after the surgical repair of TOF and, depending on the surgical approach, manifests as either progressive stenosis, regurgitation, or a combination of both. This predisposes the individual to repeated RVOT interventions with the attendant risks of multiple open-heart surgeries. The advent of transcatheter pulmonary valve replacement has reduced the operative burden, and the expansion of transcatheter pulmonary valve replacement device platforms has widened the type and size of RVOT anatomies that can be treated. This review will discuss the transcatheter therapies available throughout the lifespan of the patient with TOF.</p></div>","PeriodicalId":100249,"journal":{"name":"CJC Pediatric and Congenital Heart Disease","volume":"2 6","pages":"Pages 339-351"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772812923001306/pdfft?md5=254ef1a75ec48bb3114971e69d1f7453&pid=1-s2.0-S2772812923001306-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135346683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Physical Activity Promotion Among Individuals With Tetralogy of Fallot 法洛四联症患者的体育活动促进
CJC Pediatric and Congenital Heart Disease Pub Date : 2023-12-01 DOI: 10.1016/j.cjcpc.2023.08.002
Mackenzie Buchanan , Christopher Spence MD , Michelle Keir MD, MSc , Michael Khoury MD
{"title":"Physical Activity Promotion Among Individuals With Tetralogy of Fallot","authors":"Mackenzie Buchanan ,&nbsp;Christopher Spence MD ,&nbsp;Michelle Keir MD, MSc ,&nbsp;Michael Khoury MD","doi":"10.1016/j.cjcpc.2023.08.002","DOIUrl":"10.1016/j.cjcpc.2023.08.002","url":null,"abstract":"<div><p>In the general population, the most cited barriers to physical activity (PA) are time, energy, and motivation. Consequently, despite the significant contribution of PA to health and well-being, many individuals are insufficiently active. Physical inactivity and sedentary lifestyles increase the risk of acquired cardiometabolic disease, a risk that may complicate and is compounded by the anatomic and physiologic features inherent in the patient with repaired tetralogy of Fallot (ToF). Individuals with ToF commonly present with reduced exercise capacity and PA levels. In light of historically PA restrictive management of their heart disease, known reductions in exercise capacity among individuals with ToF are combined with psychosocial barriers to their participation, potentially establishing a cycle of further detraining, inactivity, and disease progression/health decline. To this end, children and young adults with ToF are known to have reduced self-efficacy towards PA, defined as their confidence in their ability to participate. In this review, we apply self-efficacy as an overarching mediator of PA participation and explore trends and determinants of PA participation among individuals with ToF and its subsequent impact on exercise capacity, disease risk, and health-related quality of life. We outline the rationale and strategies aimed at improving PA in children and adults with ToF and highlight current knowledge gaps and future directions in the promotion of PA in the population with ToF.</p></div>","PeriodicalId":100249,"journal":{"name":"CJC Pediatric and Congenital Heart Disease","volume":"2 6","pages":"Pages 322-334"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772812923001215/pdfft?md5=f1ec1a52d32b06e1ab4f2b597017bb95&pid=1-s2.0-S2772812923001215-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86813616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Essentials of Imaging the Repaired Tetralogy of Fallot Patient 修复后法洛四联症的影像学要点
CJC Pediatric and Congenital Heart Disease Pub Date : 2023-12-01 DOI: 10.1016/j.cjcpc.2023.08.007
Andrew M. Crean MRCP, FRCR, MPH
{"title":"Essentials of Imaging the Repaired Tetralogy of Fallot Patient","authors":"Andrew M. Crean MRCP, FRCR, MPH","doi":"10.1016/j.cjcpc.2023.08.007","DOIUrl":"10.1016/j.cjcpc.2023.08.007","url":null,"abstract":"<div><p>Tetralogy of Fallot is one of the commoner forms of congenital heart disease (CHD) with an incidence estimated at around 1 in 3000 live births. Its prevalence is roughly 5%-10% of all forms of CHD. Although it is a cyanotic disorder at presentation, early surgical repair has led to survival to adulthood in the overwhelming majority of cases. However—as with most repaired CHD—such patients are fixed, not cured, and will inevitably come to the attention of the imaging specialist. This article attempts to describe and summarize the main forms of repaired tetralogy that may be encountered in tertiary hospital imaging practice. The anatomy of different forms of tetralogy is reviewed, and relevant pathophysiology is discussed. Reference is made to 22q11 syndrome, which is often missed or not considered by even specialist congenital physicians, and the alerting features of this condition are reviewed. The benefits and challenges of computed tomography and magnetic resonance imaging in the congenital population are covered, and there is discussion regarding the various approaches to imaging available using these techniques.</p></div>","PeriodicalId":100249,"journal":{"name":"CJC Pediatric and Congenital Heart Disease","volume":"2 6","pages":"Pages 368-379"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772812923001331/pdfft?md5=bd54bd0d323e8e57134e41a1161e38f1&pid=1-s2.0-S2772812923001331-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135433164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Information for Readers 读者信息
CJC Pediatric and Congenital Heart Disease Pub Date : 2023-12-01 DOI: 10.1016/S2772-8129(23)00189-6
{"title":"Information for Readers","authors":"","doi":"10.1016/S2772-8129(23)00189-6","DOIUrl":"https://doi.org/10.1016/S2772-8129(23)00189-6","url":null,"abstract":"","PeriodicalId":100249,"journal":{"name":"CJC Pediatric and Congenital Heart Disease","volume":"2 6","pages":"Page A1"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772812923001896/pdfft?md5=0e862fb8b1a8fa3b7809b2ad92ca002b&pid=1-s2.0-S2772812923001896-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138769513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Cardiopulmonary Testing to Risk Stratify Tetralogy of Fallot Patients 心肺测试在法洛四联症患者危险分层中的作用
CJC Pediatric and Congenital Heart Disease Pub Date : 2023-12-01 DOI: 10.1016/j.cjcpc.2023.10.007
Benedetta Leonardi MD , Barbara Cifra MD
{"title":"The Role of Cardiopulmonary Testing to Risk Stratify Tetralogy of Fallot Patients","authors":"Benedetta Leonardi MD ,&nbsp;Barbara Cifra MD","doi":"10.1016/j.cjcpc.2023.10.007","DOIUrl":"10.1016/j.cjcpc.2023.10.007","url":null,"abstract":"<div><p>Neonatal repair has completely changed the clinical history of patients with tetralogy of Fallot (ToF); however, these patients carry a significant risk of severe arrhythmias and sudden cardiac death in the long term. The exact mechanism for late sudden cardiac death is multifactorial and still not well defined, and the risk stratification for primary prophylaxis in these patients remains challenging. Cardiopulmonary exercise testing (CPET) is a well-established and safe method to assess cardiopulmonary function in children and adults with congenital heart disease. Several parameters obtained with CPET have been identified as potential prognostic of major adverse cardiovascular events in congenital heart disease. CPET is routinely used to assess functional capacity also in patients with ToF, and there is some evidence showing its usefulness in predicting the cardiac adverse events in patients with repaired ToF. Current guidelines recognize the importance of CPET in the evaluation and management of patients with ToF, but there is no clear consensus on which the CPET parameter or level of exercise intolerance, as measured by CPET, is truly predictive of an increased risk of arrhythmia and major adverse cardiovascular events in this population. Therefore, the aim of this narrative review is to describe the current evidence on the potential use of CPET in the risk stratification of patients with repaired ToF.</p></div>","PeriodicalId":100249,"journal":{"name":"CJC Pediatric and Congenital Heart Disease","volume":"2 6","pages":"Pages 314-321"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772812923001586/pdfft?md5=fe53ea882319419c1501c436a4b1d4b6&pid=1-s2.0-S2772812923001586-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135849920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Aging Patient With Tetralogy of Fallot: Out of the Blue and Into the Pink 年老的法洛四联症患者:从忧郁到粉红
CJC Pediatric and Congenital Heart Disease Pub Date : 2023-12-01 DOI: 10.1016/j.cjcpc.2023.08.004
Philip Moons PhD , Bo Daelman MSc , Ariane Marelli MD, MPH
{"title":"The Aging Patient With Tetralogy of Fallot: Out of the Blue and Into the Pink","authors":"Philip Moons PhD ,&nbsp;Bo Daelman MSc ,&nbsp;Ariane Marelli MD, MPH","doi":"10.1016/j.cjcpc.2023.08.004","DOIUrl":"10.1016/j.cjcpc.2023.08.004","url":null,"abstract":"","PeriodicalId":100249,"journal":{"name":"CJC Pediatric and Congenital Heart Disease","volume":"2 6","pages":"Pages 335-338"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772812923001239/pdfft?md5=4bfd2f67c8910b0bf16918ab6e605a80&pid=1-s2.0-S2772812923001239-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76258612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global Access to Comprehensive Care for Paediatric and Congenital Heart Disease 全球获得儿科和先天性心脏病综合治疗的机会
CJC Pediatric and Congenital Heart Disease Pub Date : 2023-12-01 DOI: 10.1016/j.cjcpc.2023.10.001
Dominique Vervoort MD, MPH, MBA , Hyerang Jin MSc , Frank Edwin MBChB, DA, FWACS (CTh), FGCS , Raman Krishna Kumar MD, DM, FACC, FAHA , Mahim Malik MD, FACS , Noah Tapaua MBBS, MMed (Cardiothoracic Surgery) , Amy Verstappen MGH , Babar S. Hasan MD
{"title":"Global Access to Comprehensive Care for Paediatric and Congenital Heart Disease","authors":"Dominique Vervoort MD, MPH, MBA ,&nbsp;Hyerang Jin MSc ,&nbsp;Frank Edwin MBChB, DA, FWACS (CTh), FGCS ,&nbsp;Raman Krishna Kumar MD, DM, FACC, FAHA ,&nbsp;Mahim Malik MD, FACS ,&nbsp;Noah Tapaua MBBS, MMed (Cardiothoracic Surgery) ,&nbsp;Amy Verstappen MGH ,&nbsp;Babar S. Hasan MD","doi":"10.1016/j.cjcpc.2023.10.001","DOIUrl":"10.1016/j.cjcpc.2023.10.001","url":null,"abstract":"<div><p>Paediatric and congenital heart disease (PCHD) is common but remains forgotten on the global health agenda. Congenital heart disease is the most frequent major congenital anomaly, affecting approximately 1 in every 100 live births. In high-income countries, most children now live into adulthood, whereas in low- and middle-income countries, over 90% of patients do not get the care they need. Rheumatic heart disease is the most common acquired cardiovascular disease in children and adolescents. While almost completely eradicated in high-income countries, over 30-40 million people live with rheumatic heart disease in low- and middle-income countries. Challenges exist in the care for PCHD and, increasingly, adult congenital heart disease (ACHD) worldwide. In this review, we summarize the current status of PCHD and ACHD care through the health systems lens of workforce, infrastructure, financing, service delivery, information management and technology, and governance. We further highlight gaps in knowledge and opportunities moving forward to improve access to care for all those living with PCHD or ACHD worldwide.</p></div>","PeriodicalId":100249,"journal":{"name":"CJC Pediatric and Congenital Heart Disease","volume":"2 6","pages":"Pages 453-463"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772812923001525/pdfft?md5=64adde3ab5bbaa251f3eb8387d82e762&pid=1-s2.0-S2772812923001525-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135606332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tetralogy of Fallot Across the Lifespan: A Focus on the Right Ventricle 终生法洛四联症:以右心室为中心
CJC Pediatric and Congenital Heart Disease Pub Date : 2023-12-01 DOI: 10.1016/j.cjcpc.2023.10.009
Elie Ganni MD , Siew Yen Ho PhD , Sushma Reddy MD , Judith Therrien MD , Katherine Kearney MBBS , S. Lucy Roche MBChB, MRCPCH, MD , Konstantinos Dimopoulos MD, PhD, MSc , Luc L. Mertens MD , Yuval Bitterman MD , Mark K. Friedberg MD, PhD , Anita Saraf MD, PhD , Ariane Marelli MD, MPH , Rafael Alonso-Gonzalez MD, MSc
{"title":"Tetralogy of Fallot Across the Lifespan: A Focus on the Right Ventricle","authors":"Elie Ganni MD ,&nbsp;Siew Yen Ho PhD ,&nbsp;Sushma Reddy MD ,&nbsp;Judith Therrien MD ,&nbsp;Katherine Kearney MBBS ,&nbsp;S. Lucy Roche MBChB, MRCPCH, MD ,&nbsp;Konstantinos Dimopoulos MD, PhD, MSc ,&nbsp;Luc L. Mertens MD ,&nbsp;Yuval Bitterman MD ,&nbsp;Mark K. Friedberg MD, PhD ,&nbsp;Anita Saraf MD, PhD ,&nbsp;Ariane Marelli MD, MPH ,&nbsp;Rafael Alonso-Gonzalez MD, MSc","doi":"10.1016/j.cjcpc.2023.10.009","DOIUrl":"10.1016/j.cjcpc.2023.10.009","url":null,"abstract":"<div><p>Tetralogy of Fallot is a cyanotic congenital heart disease, for which various surgical techniques allow patients to survive to adulthood. Currently, the natural history of corrected tetralogy of Fallot is underlined by progressive right ventricular (RV) failure due to pulmonic regurgitation and other residual lesions. The underlying cellular mechanisms that lead to RV failure from chronic volume overload are characterized by microvascular and mitochondrial dysfunction through various regulatory molecules. On a clinical level, these cardiac alterations are commonly manifested as exercise intolerance. The degree of exercise intolerance can be objectified and aid in prognostication through cardiopulmonary exercise testing. The timing for reintervention on residual lesions contributing to RV volume overload remains controversial; however, interval assessment of cardiac function and volumes by echocardiography and magnetic resonance imaging may be helpful. In patients who develop clinically important RV failure, clinicians should aim to maintain a euvolemic state through the use of diuretics while paying particular attention to preload and kidney function. In patients who develop signs of cardiogenic shock from right heart failure, stabilization through the use of inotropes and pressor is indicated. In special circumstances, the use of mechanical support may be appropriate. However, cardiologists should pay particular attention to residual lesions that may impact the efficacy of the selected device.</p></div>","PeriodicalId":100249,"journal":{"name":"CJC Pediatric and Congenital Heart Disease","volume":"2 6","pages":"Pages 283-300"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772812923001604/pdfft?md5=37edda3a327b8bcecefd0fd85d0142e2&pid=1-s2.0-S2772812923001604-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135965850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plastic Bronchitis in a Child With Fontan Physiology After COVID-19 Infection COVID-19 感染后一名丰唐生理学患儿的塑料支气管炎
CJC Pediatric and Congenital Heart Disease Pub Date : 2023-12-01 DOI: 10.1016/j.cjcpc.2023.10.004
Helena Rae Woodhouse MD , Olubunmi Ogunsanya MD , Aaron St-Laurent MD , Michael Grattan MD , Marisha McClean MBBS, DM (Peads)
{"title":"Plastic Bronchitis in a Child With Fontan Physiology After COVID-19 Infection","authors":"Helena Rae Woodhouse MD ,&nbsp;Olubunmi Ogunsanya MD ,&nbsp;Aaron St-Laurent MD ,&nbsp;Michael Grattan MD ,&nbsp;Marisha McClean MBBS, DM (Peads)","doi":"10.1016/j.cjcpc.2023.10.004","DOIUrl":"10.1016/j.cjcpc.2023.10.004","url":null,"abstract":"","PeriodicalId":100249,"journal":{"name":"CJC Pediatric and Congenital Heart Disease","volume":"2 6","pages":"Pages 481-483"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772812923001550/pdfft?md5=6d5a38696a70797b922d632b0f117019&pid=1-s2.0-S2772812923001550-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135762520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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