{"title":"An evaluation of the use of cisapride in horses with chronic grass sickness (equine dysautonomia)","authors":"E.M. Milne , D.L. Doxey, M.P. Woodman, D. Cuddeford, R.A. Pearson","doi":"10.1016/S0007-1935(96)80006-6","DOIUrl":"10.1016/S0007-1935(96)80006-6","url":null,"abstract":"<div><p>A clinical trial was carried out to determine the effect of cisapride on rateof passage of digesta and clinical parameters in horses with chronic grass sickness. Sixteen horses were given intramuscular cisapride (0.1 mg kg<sup>−1</sup> three times daily) (group I), and 15 received oral cisapride (0.8 mg kg<sup>−1</sup> three times daily) (group O). A liquid-phase marker (cobalt-EDTA) and a solid-phase marker (polystyrene pellets) were given by stomach tube at the beginning of each of three consecutive 7 day periods, i.e., before, during and after cisapride therapy. Seven horses in each group completed the rate of passage trial; the remainder provided clinical data only. The rate of passage was found to be significantly faster after cisapride therapy than before. Comparison with data from 20 normal animals showed a trend towards normal rates of passage after therapy. In cases that died during the trial, the caecum and large colon were the main sites of pellet retention. Dry matter intake was significantly higher after therapy than before in group O and dry matter output was higher after treatment than before in both groups. Gut auscultation score increased in both groups in the periods during and after cisapride administration but heart rate was unaffected. Diarrhoea and colic occurred in each group but its occurrence was not associated with cisapride therapy. The results suggest that by increasing gut motility, cisapride is of benefit in the management of selected cases of chronic grass sickness.</p></div>","PeriodicalId":100203,"journal":{"name":"British Veterinary Journal","volume":"152 5","pages":"Pages 537-549"},"PeriodicalIF":0.0,"publicationDate":"1996-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0007-1935(96)80006-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19850830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Concentrations of steroids and biochemical constituents in follicular fluid of buffalo cows during different stages of the oestrous cycle","authors":"H.M. Eissa","doi":"10.1016/S0007-1935(96)80009-1","DOIUrl":"10.1016/S0007-1935(96)80009-1","url":null,"abstract":"<div><p>One of the factors controlling ovarian physiology in cattle is the alterationthat occurs in the hormonal and biochemical composition of follicular fluid. Because they are ill-defined in buffaloes, the present study was aimed at determining changes in the follicular fluid collected from 197 pairs of buffalo ovaries after slaughter. Total oestrogens, progesterone, calcium, inorganic phosphorus and total protein were found to be higher before oestrus and reached their peak values during oestrus. Glucose concentrations were maximal before oestrus. Testosterone, total corticosteroids and acid phosphatase concentrations increased during metoestrus peaking during dioestrus. Alkaline phosphatase concentration was higher during dioestrus. Ratios and correlations between changes in concentrations of the different follicular steroids were determined.</p></div>","PeriodicalId":100203,"journal":{"name":"British Veterinary Journal","volume":"152 5","pages":"Pages 573-581"},"PeriodicalIF":0.0,"publicationDate":"1996-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0007-1935(96)80009-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19850180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic aids and prognostic indicators forchronic grass sickness: Possibilities for the future","authors":"D. Murphy, S. Love","doi":"10.1016/S0007-1935(96)80003-0","DOIUrl":"10.1016/S0007-1935(96)80003-0","url":null,"abstract":"","PeriodicalId":100203,"journal":{"name":"British Veterinary Journal","volume":"152 5","pages":"Pages 497-499"},"PeriodicalIF":0.0,"publicationDate":"1996-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0007-1935(96)80003-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19850827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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