中国激光医学杂志最新文献

{"title":"Raman fl uorescence technologies for early detection of infl ammatory and oncological disorders as a part of public health strategy and a tool for improving the quality of medical care: a review","authors":"A. Timurzieva","doi":"10.37895/2071-8004-2021-25-4-42-50","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-4-42-50","url":null,"abstract":"The increasing morbidity and mortality rate in inflammatory and oncological diseases requires determining the public health strategies for early  detection of such disorders and improving the quality of medical care. For this goal, high-tech modalities with high sensitivity, specificity and  accuracy are to be worked out. Rаman fluorescent medical technologies (RFMT) can be successfully applied in the diagnostics of inflammatory  and tumor diseases if to develop a specific algorithm for express analysis of histological, physiological, microbiological and other components  of biological tissues. The given article presents a brief overview on the application of Raman fluorescence spectrometry in the diagnostics  of diseases. This medical technology, which utilizes the phenomenon of tissue autoflorescence and Raman light scattering, is a promising  tool for early diagnostics of different inflammatory and oncological pathologies. The described nоn-invasive method allows to make an express  assessment of metabolic, morphometric and functional tissue parameters in intact and in pathological tissue. The present discussion is aimed  to find out points for the application of Rаman fluorescence spectrometry and its various modifications; to assess its potentials for screening;  to develop a specific algorithm for the diagnostics of inflammatory and tumor pathologies. RFMT is a promising modality for future applications  so as to improve the quality of medical care by early detection of inflammatory and tumor diseases and early prescription of rational therapy.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"34 14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77238903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gelfond Mark Lvovich (02.11.1945 – 05.12.2021)","authors":"A. Editorial","doi":"10.37895/2071-8004-2021-25-4-60","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-4-60","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72379274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syndrome of “adjacent level” in surgery of the lumbar spine. Minimally invasive treatment methods","authors":"A. Gorbunov, V. Potapov, Z. Koshkareva, A. Zhivotenko, S. D. Glotov, S. Larionov, O. Sklyarenko","doi":"10.37895/2071-8004-2021-25-4-29-34","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-4-29-34","url":null,"abstract":"An analysis of the effectiveness of laser vaporization in 67 patients (23 men, 44 women) with the syndrome of the “adjacent level” of the lumbarspine, who had previously undergone decompressive-stabilizing operations, is presented. The mean age of the patients was 48.3 years (from37 to 54 years).The most common cause of pain syndrome recurrence was protrusion of the intervertebral discs (60 people, 90 %). A positive result of laservaporization in the early postoperative period was achieved in 62 patients (92.5 %). Analysis of the results of treatment in 32 patients in the interimperiod revealed excellent results in 5 (15.5 %) patients, good results – in 12 (37.5 %) patients, and satisfactory results – in 15 (47 %) patients.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88070668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photodynamic activity of water dispersion of gold nanoparticles for treating experimental purulent wounds","authors":"T. Shulgina, E. F. Stranadko, O. Nechaeva, E. Glinskaya, K. Zubova, D. A. Schnaider, N. V. Bespalova","doi":"10.37895/2071-8004-2021-25-4-35-41","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-4-35-41","url":null,"abstract":"Introduction. Antimicrobial photodynamic therapy is one of the highly effective techniques for treating infectious lesions of the skin and soft tissues. However, the search for safe photosensitizers remains relevant.Purpose: to study the application of aqueous dispersion of gold nanoparticles as a potential photosensitizer for antimicrobial photodynamic therapy in experimental purulent wounds.Material and methods. Photosensitizing ability of aqueous dispersion of gold nanoparticles stabilized with polyvinyl alcohol was studied on experimental full-thickness purulent wounds in rats. Semiconductor laser (Alcom Medica, St. Petersburg) with wavelength 405 nm was used.Results. It has been found out that pretreatment of wounds with nanostructures followed by photodynamic exposure gives a 1.6-fold reduction of healing process of wound defects in laboratory animals compared to the control group. in experimental animals, an effective cleansing of wounds from purulent contents was observed as well.Conclusion. An aqueous dispersion of gold nanoparticles stabilized with polyvinyl alcohol can be considered as an effective photosensitizer for antimicrobial photodynamic therapy.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90873485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laser treatment of chondromalacia lesions in the articular cartilage","authors":"A. Lychagin, S. Ivannikov, V. Yusupov, L. Semenova, E. Startseva, V. Surin, I. O. Tinkova, A. I. Naimann, T. A. Zharova, P. A. Przhevalsky, Y. Yan","doi":"10.37895/2071-8004-2021-25-4-9-15","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-4-9-15","url":null,"abstract":"Objective: to select optimal parameters of two-wave near-infrared laser irradiation for the arthroscopic treatment of chondromalacia foci  in the articular cartilage.  Material and methods. Bull articular cartilages were treated with laser light delivered by a fifi ber and having various parameters. Human articular  cartilages with chondromalacia foci taken during the total knee replacement were also treated with laser light delivered by a fifi ber and having  various parameters. The processed cartilage samples were examined macroscopically and then histologically. Changes in the structure of ar[1] ticular cartilage after laser irradiation were assessed.  Results. A two-second irradiation with two-wave laser light (λ = 0.97 μm / 30 W and λ = 1.55 μm / 15 W) causes a rapid “melting” of lesion margins  without macroscopically visible carbonization with a wide thermally affected zone in the irradiated area. Histologically, cartilage preparations  irradiated with two-wave laser light (wavelengths λ = 1.55 μm / 5 W and λ = 0.97 μm / 3 W) for 2 sec demonstrated slight changes in the cartilage  structure without thermal destruction of chondrocytes.Conclusion. The optimal combination for laser irradiation of the cartilage tissue in the saline solution environment which restores articular cartilage  shape is two-wave laser light λ = 0.97 μm at power of 3 W and λ = 1.55 μm at power of 5 W from the distance of 1–2 mm under 2 sec exposure.   ","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91182469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-intensity laser photocoagulation and cryodestruction in the treatment of patients with skin scars","authors":"V. Yudin, I. V. Vasin, T. A. Kachanova","doi":"10.37895/2071-8004-2021-25-4-23-34","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-4-23-34","url":null,"abstract":"Purpose: to assess the effects of combined application of high-level laser photocoagulation and simultaneous cryodestruction at pathological scars on the skin.Material and methods. Two groups included patients of both genders aged 18 and older. Patients from the fi rst (main) group (n = 60) had simultaneous high-level laser irradiation and cryodestruction on scar tissue; patients from the second (control) group (n = 30) were treated separately with laser irradiation and cryodestruction. For laser irradiation, laser devise CO2-laser AKHIL with wavelength 10.6 μm, pulsed frequency 10–20 Hz and power 5–15 W was used. For cryodestruction, apparatus “KRIO-RM-01” was used: tip cooling speed of 220 °C/min, the temperature of 180 °C on the tip working part, exposure time – 15–20 sec. The treated patients had hypertrophic and keloid scars. Etiologically, scars were of post-traumatic, postoperative, post-eruptive types. Evaluation criteria were histological examination of biopsy material with eosinhematoxylin, patients’ quality of life, examination of scar zone.Results. The obtained results demonstrate that the combined application of two physical factors (laser + cryo) at scar tissue increases satisfactory outcomes in patients with hypertrophic scars by 75 % and by 53.4 % in the control group. Relapses were seen in both groups: 25 % in the main group and 46 % in the control group. Morphologically, one can see positive changes in degradation of rough fi brous tissue.Conclusion. A combined application of high-intensity laser photocoagulation and simultaneous cryodestruction has been proven to be effective in patients with pathological skin scars.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81604117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The combined effect of low-level laser therapy and dietary supplements at the microcirculation system in athletes","authors":"T. M. Brook, F. Litvin, K. Efremenkov, V. Kozlov","doi":"10.37895/2071-8004-2021-25-4-16-22","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-4-16-22","url":null,"abstract":"The problem of athletes’ body resistance to effects of extreme loadings which lead to decreased adaptive capabilities of the body and over training is particularly relevant in modern sports. In order to improve the physical performance of athletes, there is a constant search for new  tools and methods.  Aim: to study the effect of dietary supplements at the microcirculation system, both in isolated use and in combination with low-level laser therapy.  Material and methods. The study included 28 highly qualififi ed male all-around athletes of the CMC and MS levels. To study the parameters  of skin microcirculation, laser Doppler flfl owmetry (LDF) was used, device “LAKK-02” (NPP “LAZMA”). The following parameter was calculated:  microcirculation index (MI) proportional to the number of red blood cells in the diagnosed volume and their average velocity. The received  signal give the information about endothelial, neurogenic and myogenic active mechanisms of vascular tone regulation and passive mechanisms – respiratory and cardiac flfl uctuations in blood flfl ow; flfl ax index, specififi c oxygen consumption index by tissues, erythrocyte concentration  index in the probed blood volume and the ratio of coenzymes of reduced nicotinamide adenine dinucleotide (NADH) and oxidized flfl avinadenine  dinucleotide (FAD) (NADH/FAD).  Results. After isolated use of dietary supplements, the level of perfusion increases signififi cantly by 48 % (p < 0.05), and the value of the flfl ax  increases by 78 % (p < 0.05). More red blood cells by 22 % (p < 0.05) are released from blood depots into the microcirculatory bed. The tone  of arterioles decreases by 48 % (p < 0.05), of precapillary sphincters – by 59 % (p < 0.05). In mitochondria, ratio of NADH/FAD coenzymes  increases by 55 % (p < 0.05).  Conclusion. Laser radiation in combination with dietary supplements optimizes recovery processes in the body of athletes who are subjected  to heavy physical exertion. Under the combined effect, the intensity of microcirculation increases, oxygen output of erythrocytes by hemoglobin  improves as well as its active diffusion from blood into tissues and participation in the ATP synthesis at the level of cell mitochondrial. It is worth  noting that there is similarity in the isolated use of dietary supplements and in combination with low-energy laser radiation which enhances  the mechanism of action of dietary supplements.  ","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75550024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-level laser light in the rehabilitation of cancer patients","authors":"Y. Y. Gorchak, G. Guens, E. Prazdnikov, M. L. Stakhanov, D. Reshetov, D. Khlanta, V. B. Knyazkov, S. E. Ovcharov","doi":"10.37895/2071-8004-2021-25-3-47-58","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-3-47-58","url":null,"abstract":"Despite of an obvious success in the management of cancer patients and in the quality of medical care for them, however there are still open questions on the effectiveness of prevention and treatment of complications after surgery, chemotherapy, and radiotherapy, as well as on the quality of comprehensive rehabilitation of such patients. One of the possible ways to solve these issues is low-level laser therapy.Laser therapy in Russia has been successfully used in many areas of modern clinical medicine for more than 50 years; it is still developing and improving. Main advantages of laser therapy are simplicity, comfort, and safety for patients, as well as low costs.The widespread use of low-level laser light has experimental and clinical justification. Awareness in principles of dosing, methodological features of laser procedures, justified prescription and strict compliance with indications and contraindications can ensure high effectiveness of the discussed therapy in oncologic patients.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84136657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bispectral photodynamic therapy after the extraction of third molars","authors":"K. A. Prygunov, N. N. Abolmasov, A. R. Yevstigneev","doi":"10.37895/2071-8004-2021-25-3-34-39","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-3-34-39","url":null,"abstract":"Findings obtained after the present trial have confirmed that in patients with extracted third molars reparative processes in wounds are more rapid if wound holes are treated with low-level bispectral laser light.Purpose: to confirm improved reparation, less pain syndrome, and less inflammatory reactions in wounds after the extraction of third molars if laser photodynamic therapy was used in the postoperative period.Material and methods. Given the extraction of eight teeth is a rather traumatic procedure, the authors proposed a technique for treating inflammatory processes in the mucous of maxillofacial area. To implement this technique in the postoperative period, they treated wound surface with photodynamic technique including a photoactive sensitizer. If upper and lower wisdom teeth were removed simultaneously, phototherapy with low-level laser light and bispectral nozzle was applied unilaterally on days 2, 3 and 5, while the other side was not treated at the rehabilitation period. To confirm the effectiveness of the proposed curative technique, scrapes from the wound surface of teeth holes were taken and examined cytologically on days 3, 7 and 12. Staining by Pappenheim and azur-eosin was applied. A randomized simple blind experiment was conducted; a double-blind experiment was a part of morphological examination.Results. Smears from the wound surface were examined on days 3, 7 and 12 to find qualitative and quantitative composition of cytological preparations. A statistically significant difference (p < 0.05) was found indicating that the performed physiotherapeutic care significantly improves reparative processes.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77869952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photodynamic therapy of penile leukoplakia: a case report","authors":"N. Shanazarov, B. G. Kassymov, T. Muratov, S. Zinchenko","doi":"10.37895/2071-8004-2021-25-3-29-33","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-3-29-33","url":null,"abstract":"Purpose: to describe a clinical case of successful application of photodynamic therapy (PDT) in a patient with leukoplakia of the glans penis skin.Material and methods. For PDT, chlorin-type photosensitizer “Photolon” was used. The photosensitizer (lyophilized powder) was diluted in 200.0 ml of 0.9 % sodium chloride solution, administered intravenously at dosage 1.5 mg/kg of body weight. After 2.5 hours, intravenous laser blood irradiation was performed with “Lakhta-Milon” laser device (output power – 100 mW, exposure – 30 minutes). Before PDT, fluorescence diagnostics in ultraviolet light with wavelength 395–405 nm was performed. PDT technique was single-field irradiation with output power 1800 mW (1.8 W), irradiation energy density – 150 J/cm2. Power density of laser light was 200 mW/cm2. Exposure time – 14 min.Results. After treatment, complete regression of the pathological focus and regeneration of healthy tissue were marked (one month).Conclusion. PDT in a patient with leukoplakia of glans penis is an effective and safe curative technique.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83320622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}