激光治疗关节软骨软化症病变

A. Lychagin, S. Ivannikov, V. Yusupov, L. Semenova, E. Startseva, V. Surin, I. O. Tinkova, A. I. Naimann, T. A. Zharova, P. A. Przhevalsky, Y. Yan
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引用次数: 0

摘要

目的:选择关节镜下双波近红外激光照射治疗关节软骨软化灶的最佳参数。材料和方法。采用不同参数的激光对牛关节软骨进行治疗。在全膝关节置换术中取下的有软骨软化灶的人关节软骨也用激光治疗,激光由激光传送,具有不同的参数。处理后的软骨标本进行了宏观和组织学检查。观察激光照射后骨突软骨的结构变化[1]。结果。用两波激光(λ = 0.97 μm / 30 W和λ = 1.55 μm / 15 W)照射2秒后,病变边缘迅速“熔化”,但未出现宏观可见的碳化现象,并在照射区域形成较宽的热影响区。组织学上,两波激光(波长分别为λ = 1.55 μm / 5 W和λ = 0.97 μm / 3 W)照射2秒后,软骨组织结构发生轻微变化,软骨细胞无热破坏。在盐水环境下,激光照射软骨组织的最佳组合是波长为λ = 0.97 μm,功率为3w和λ = 1.55 μm,功率为5w的两波激光,照射距离为1 ~ 2mm,照射时间为2秒。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Laser treatment of chondromalacia lesions in the articular cartilage
Objective: to select optimal parameters of two-wave near-infrared laser irradiation for the arthroscopic treatment of chondromalacia foci  in the articular cartilage.  Material and methods. Bull articular cartilages were treated with laser light delivered by a fifi ber and having various parameters. Human articular  cartilages with chondromalacia foci taken during the total knee replacement were also treated with laser light delivered by a fifi ber and having  various parameters. The processed cartilage samples were examined macroscopically and then histologically. Changes in the structure of ar[1] ticular cartilage after laser irradiation were assessed.  Results. A two-second irradiation with two-wave laser light (λ = 0.97 μm / 30 W and λ = 1.55 μm / 15 W) causes a rapid “melting” of lesion margins  without macroscopically visible carbonization with a wide thermally affected zone in the irradiated area. Histologically, cartilage preparations  irradiated with two-wave laser light (wavelengths λ = 1.55 μm / 5 W and λ = 0.97 μm / 3 W) for 2 sec demonstrated slight changes in the cartilage  structure without thermal destruction of chondrocytes.Conclusion. The optimal combination for laser irradiation of the cartilage tissue in the saline solution environment which restores articular cartilage  shape is two-wave laser light λ = 0.97 μm at power of 3 W and λ = 1.55 μm at power of 5 W from the distance of 1–2 mm under 2 sec exposure.   
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期刊介绍: The main columns of "Chinese Journal of Laser Medicine & Surgery" include treatises, which report the latest research results in basic research and clinical trials in the field of laser medicine; comprehensive reviews of the latest research progress in laser medicine at home and abroad. In addition, there are short reports and excerpts from foreign journals, conference news and other columns. The journal has published a large number of papers on basic research on laser medicine and applied research in various clinical subjects, aiming to play a positive role in promoting the application of laser in medicine and improving the level of laser medicine research.
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