Anesthesiology and Perioperative Science最新文献

{"title":"The innovative approach of continuous lateral parasacral ischial plane block: supine position","authors":"Peng Ye, Cansheng Gong, Jing Zhuang, Hanliang Fan, Xuan Pan, Xiaochun Zheng, Ting Zheng","doi":"10.1007/s44254-025-00101-w","DOIUrl":"10.1007/s44254-025-00101-w","url":null,"abstract":"","PeriodicalId":100082,"journal":{"name":"Anesthesiology and Perioperative Science","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44254-025-00101-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving perioperative normothermia: insights from clinical practice","authors":"Jingyuan Chen, Yaqing Zhan, Xu Zhao, Wenqi Huang","doi":"10.1007/s44254-025-00098-2","DOIUrl":"10.1007/s44254-025-00098-2","url":null,"abstract":"","PeriodicalId":100082,"journal":{"name":"Anesthesiology and Perioperative Science","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44254-025-00098-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in the application of platelet-rich plasma in peripheral nerve injuries","authors":"Xiao-Yu Dou,&nbsp;Min An","doi":"10.1007/s44254-025-00100-x","DOIUrl":"10.1007/s44254-025-00100-x","url":null,"abstract":"<div><p>Peripheral nerve injury (PNI) can occur after various types of trauma; these are common clinical injuries. These injuries often result in chronic conditions such as neuropathic pain and permanent disabilities, severely affecting quality of life and work. Achieving optimal repair of injured peripheral nerves remains a focal point of clinical research. In recent years, platelet-rich plasma (PRP) has been increasingly applied in clinical settings due to associated high concentration of various growth factors that promote tissue repair. Here we review advances in PNI repair and the prospect of using autologous PRP as a treatment paradigm.</p></div>","PeriodicalId":100082,"journal":{"name":"Anesthesiology and Perioperative Science","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44254-025-00100-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143845602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: “Impact of opioids on hospital stay and mortality in patients undergoing abdominal surgeries”","authors":"Han-bing Xu,&nbsp;Chong Fu,&nbsp;Zihan Yan,&nbsp;Hua-yue Liu,&nbsp;Fu-hai Ji","doi":"10.1007/s44254-025-00102-9","DOIUrl":"10.1007/s44254-025-00102-9","url":null,"abstract":"","PeriodicalId":100082,"journal":{"name":"Anesthesiology and Perioperative Science","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44254-025-00102-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143840345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-omics analysis and machine learning in the study of intestinal ischemia/reperfusion injury","authors":"Xiao-dong Chen,&nbsp;Ke-xuan Liu","doi":"10.1007/s44254-025-00097-3","DOIUrl":"10.1007/s44254-025-00097-3","url":null,"abstract":"","PeriodicalId":100082,"journal":{"name":"Anesthesiology and Perioperative Science","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44254-025-00097-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the association of erythrocytic NO-ferroheme, a surrogate marker of endothelial function with perioperative cardiovascular events in low/intermediate risk patients undergoing elective non-cardiac surgery","authors":"Hasnae Boughaleb,&nbsp;Jerome Linden,&nbsp;Arvind Soni,&nbsp;Nathalie Fabian,&nbsp;Irina Lobysheva,&nbsp;Virginie Montiel,&nbsp;Mona Momeni,&nbsp;Marie-Agnès Docquier,&nbsp;Annie Robert,&nbsp;Nancy Van Overstraeten,&nbsp;Jean-Luc Balligand","doi":"10.1007/s44254-025-00096-4","DOIUrl":"10.1007/s44254-025-00096-4","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;p&gt;Pre-operative assessment of cardiovascular risk currently relies on scores, such as the American Society of Anesthesiologists (ASA) score, biased towards high-risk, but neglecting middle/lower risk patients. Endothelial dysfunction is a precursor to cardiovascular events (CVEs), due to impaired nitric oxide (NO) bioavailability. We previously showed that the erythrocytic NO-ferroheme including the 5-coordinated NO-heme-α-hemoglobin (HbNO), a complex between NO and deoxyhemoglobin correlates with endothelial function assessed by digital tonometry. The aim of this study was to evaluate if HbNO is associated with the different cardiovascular risk factors and to explore its association with CVE in patients undergoing elective non-cardiac surgery.&lt;/p&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;We conducted a prospective, monocentric study in adult patients scheduled for elective non-cardiac surgery. At preoperative visit, blood samples were collected, and erythrocytes isolated to measure baseline HbNO levels, along with other biomarkers routinely used to evaluate pre-operative risk factors. NO-ferroheme signals were quantified using electron paramagnetic resonance spectroscopy. Follow-up visits and data analysis using electronic health records were conducted at 1-, 3-, 6- and 12- months postoperatively. The primary endpoint was the occurrence of a composite of CVE, including arrhythmias, chest pain/unstable angina, myocardial infarction/ischemia, pulmonary edema, pulmonary embolism, stroke, deep venous thrombosis, cardiac failure and death of any cause.&lt;/p&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;Between November 2019 and June 2022, 2,500 patients were screened and 1,066 patients underwent an elective non-cardiac surgery. Among the 1,066 patients kept for the final analysis, 23 subjects developed a peri-operative CVE up to 30 days after surgery (&lt;i&gt;p-&lt;/i&gt;30d CVE). Linear regression analysis revealed several independent factors significantly correlated with HbNO levels, including hemoglobin, anticoagulant usage, and smoking status. Patients who developed &lt;i&gt;p-&lt;/i&gt;30d CVE exhibited lower mean HbNO levels (124.2 ± 96.6 nM) compared to those who did not (154.8 ± 104.1 nM; &lt;i&gt;p = &lt;/i&gt;0.028). Using a threshold of 124 nM for HbNO, levels below this cutoff (HbNO &lt; 124 nM) were associated with an increased risk of &lt;i&gt;p-&lt;/i&gt;30d CVE (OR [95% CI] = 4.21 [1.55–11.41]), as did classification in ASA III or higher (OR [95% CI] = 3.23 [1.38–7.59]). However, after excluding patients at high risk of CVE a priori, HbNO &lt; 124 nM remained associated to &lt;i&gt;p-&lt;/i&gt;30d CVE (OR [95% CI] = 5.52 [1.57–19.33]) while the association to ASA-score was no longer significant (OR [95% CI] = 0.89 [0.20–3.97]).&lt;/p&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;p&gt;In patients scheduled for non-cardiac surgery, known cardiovascular risk factors, such as active smoking independently and negatively correlates with erythrocytic NO-ferroheme including HbNO. In patients without severe comorbidities, despite the limited number of CVEs obser","PeriodicalId":100082,"journal":{"name":"Anesthesiology and Perioperative Science","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44254-025-00096-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topical sevoflurane in the treatment of complex wounds: new application perspectives","authors":"Wei Xu,&nbsp;Hailong Bing,&nbsp;Wangli Tian,&nbsp;Linhan Wang,&nbsp;Zhengyuan Xia,&nbsp;Qinjun Chu","doi":"10.1007/s44254-025-00099-1","DOIUrl":"10.1007/s44254-025-00099-1","url":null,"abstract":"","PeriodicalId":100082,"journal":{"name":"Anesthesiology and Perioperative Science","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44254-025-00099-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143786581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic prediction model for chronic postsurgical pain among adult patients: a systematic review and meta-analysis","authors":"Yanjie Dong,&nbsp;Huolin Zeng,&nbsp;Lei Yang,&nbsp;Huan Song,&nbsp;Qian Li","doi":"10.1007/s44254-025-00093-7","DOIUrl":"10.1007/s44254-025-00093-7","url":null,"abstract":"<div><h3>Purpose</h3><p>Chronic postsurgical pain (CPSP) presents a significant impact in the postoperative recovery, affecting patients’ outcomes and quality of life. Numerous prognostic prediction models have been developed to predict the risk of CPSP, however, the clinical utility remains variable. This systematic review and meta-analysis aimed to critically assessed and synthesize the existing CPSP prognostic prediction models in adult patients.</p><h3>Methods</h3><p>A comprehensive literature search was conducted in PubMed, Embase, and the Cochrane library up to August 2024. A total of 22 models were included in the systematic review, with 19 models subsequently integrated into the meta-analysis.</p><h3>Results</h3><p>The overall pooled C-index of the models was 0.79 (95% confidence interval [CI]: 0.75, 0.83; I² = 88.6%). For studies evaluating CPSP at 3 months postoperatively, the pooled C-index was 0.80 (95% CI: 0.73, 0.87; I² = 82.1%). At 4 months, the pooled C-index was 0.75 (95% CI: 0.62, 0.87; I² = 82.8%), while studies considered CPSP at 6 months showed a pooled C-index of 0.81 (95% CI: 0.73, 0.89; I² = 93.8%). For 12 months post-surgery, the C-index was 0.77 (95% CI: 0.74, 0.79; I² = 0%). Among models with external validation, the C-index was 0.76 (95% CI: 0.70, 0.82; I² = 68.2%). For orthopedic surgery, the C-index was 0.82 (95% CI: 0.74, 0.91; I² = 92.7%). For breast surgery, the C-index was 0.78 (95% CI: 0.75, 0.81; I² = 0%). For studies reported C-index, the C-index was 0.70 (95% CI: 0.66, 0.73; I² = 0%) while the C-index was 0.81 (95% CI: 0.77, 0.85; I² = 88%) for studies reported area under receiver operating characteristic curve.</p><h3>Conclusions</h3><p>While prognostic prediction models demonstrated promising discriminative performance, the high overall risk of bias raises concerns about their quality and generalizability. These findings underscore the urgent need for rigorously designed and externally validated models to improve CPSP risk prediction in clinical practice.</p></div>","PeriodicalId":100082,"journal":{"name":"Anesthesiology and Perioperative Science","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44254-025-00093-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143769708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of liposomal bupivacaine administration in the pediatric population: a scoping review of the literature","authors":"Tarika D. Patel,&nbsp;Matthew Dusza,&nbsp;Cheng-Ting Lee","doi":"10.1007/s44254-025-00095-5","DOIUrl":"10.1007/s44254-025-00095-5","url":null,"abstract":"<div><p>Liposomal bupivacaine (LB; Exparel) is a slow-release formulation of bupivacaine used for postoperative pain control that allows for steady and sustained release of bupivacaine over an extended period of time. Although it has been thoroughly investigated in adults since initial approval in 2011, the efficacy and safety of LB use in pediatric patients have still not been fully explored since its more recent approval for pediatrics in March 2021. To assess the current state of the literature regarding the safety and efficacy of LB use in pediatric patients, we queried three online electronic databases. Overall, 26 articles encompassing 1,496 LB patients were selected for review. Outcome data on adverse events, postoperative opioid use, postoperative pain, length of hospital stay, and total hospital costs were extracted. Two published randomized controlled trials were identified, in addition to 15 retrospective cohort studies and 9 case series/case reports. The most commonly reported measures were postoperative opioid use and pain scores, followed by adverse events, length of hospital stay, and lastly, hospital costs. There were no reported instances of local anesthetic systemic toxicity, and no trends were found between surgery type or administration method (nerve block versus intramuscular injection) and surgical outcomes. While the existing literature suggests that LB may reduce pain scores, hospital costs, length of hospital stay, and opioid use, these findings are significantly limited by potential conflicts of interest, gaps in study design, and inconsistent outcome measures. Overall, there is a scarcity of high-quality studies comparing LB to more commonly used local anesthetics, and further investigation through high-quality studies, such as randomized controlled trials, is warranted to determine if LB should be included as part of a multimodal regimen for postoperative pain management in pediatric patients.</p></div>","PeriodicalId":100082,"journal":{"name":"Anesthesiology and Perioperative Science","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44254-025-00095-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative strokes: uncovering risks, sequelae, and a therapeutic future","authors":"Aravind Ganesh","doi":"10.1007/s44254-025-00089-3","DOIUrl":"10.1007/s44254-025-00089-3","url":null,"abstract":"<div><p>This article provides an overview of perioperative strokes—a pressing concern given the rising number of surgical or interventional procedures performed worldwide. Mechanisms underlying perioperative stroke include atherosclerotic plaque instability, induction of a pro-inflammatory state (aggravated by vascular risk factors), hemodynamic dysfunction through hypotension and blood loss, and disruption of the endothelial glycocalyx. The frequency of perioperative stroke varies considerably depending on the type of procedure, being higher with aortic valve and neurovascular procedures. Covert or silent strokes are commonly seen on post-operative magnetic resonance imaging in as many as one in two patients after procedures like brain aneurysm coiling. Risk factors for perioperative stroke include patient factors such as age, sex, race, and comorbidities, as well as operator and procedural factors such as operator experience, institutional procedural volume, use of certain devices, and vascular access site. Overt periprocedural stroke is associated with higher mortality, longer hospital stays, and higher long-term disability. The long-term sequelae of covert strokes are still being characterized, but recent studies have indicated that a higher burden of such infarcts is associated with worse functional and cognitive outcomes. Key considerations to prevent perioperative strokes include screening plus risk factor control, pre-medication, and procedural considerations including anesthetic choice. The management of perioperative ischemic stroke has been aided by advancements in reperfusion therapies and stroke systems of care that allow rapid treatment of major stroke. Ongoing work seeks to address the enduring need for evidence-based therapeutic strategies to prevent these strokes and mitigate their adverse impact.</p></div>","PeriodicalId":100082,"journal":{"name":"Anesthesiology and Perioperative Science","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44254-025-00089-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143553943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}