Agriculture Communications最新文献

{"title":"Unlocking nature's potential: Novel isomagnolone analogues as broad-spectrum antimicrobial agents for plant disease control","authors":"Xiaoting Yan ,&nbsp;Xueyu Li ,&nbsp;Meijuan Huang ,&nbsp;Hang Liu ,&nbsp;Linfang Wang ,&nbsp;Huijuan Li ,&nbsp;Lei Wang ,&nbsp;Lin Shen ,&nbsp;Ruige Yang ,&nbsp;Yong Guo","doi":"10.1016/j.agrcom.2024.100030","DOIUrl":"https://doi.org/10.1016/j.agrcom.2024.100030","url":null,"abstract":"<div><p>In an effort to develop novel, less toxic, and effective controls for plant diseases, we aimed to identify derivatives of the natural product isomagnolone with antimicrobial activity. We established a facile method for the synthesis of isomagnolone and its isomer <strong>Ⅱ</strong>, and prepared a series of novel isomagnolone analogues bearing <em>N</em>-(1,3-thiazol-2-yl)amides <strong>Ⅲ1</strong>–<strong>30</strong>. The structures of <strong>Ⅲ1</strong>–<strong>30</strong> were determined by IR, ¹H NMR, ¹³C NMR, and ESI-MS. Among them, compounds <strong>Ⅲ24</strong> and <strong>Ⅲ26</strong> exhibited potent antifungal activity against four fungi with EC₅₀ values substantially lower than that of the positive control, hymexazol. Additionally, the antibacterial results showed that <strong>Ⅲ20</strong> and <strong>Ⅲ22</strong> displayed more potent antibacterial activity against <em>Xanthomonas oryzae</em> pv. <em>oryzae</em> (<em>Xoo</em>) with EC₅₀ values of 12.6 and 10.3 ​μg/mL, respectively, approximately 2-fold lower than that of the positive control, thiodiazole copper (EC₅₀: 24.0 ​μg/mL). Structure-activity relationships suggested that the antifungal activity of title isomagnolone analogues was favored when the substituent (R) was pyridyl or the 2-chloro-3-pyridyl group. Mechanism of action studies revealed that <strong>Ⅲ22</strong> could disrupt bacterial membranes, thus resulting in cell death. Furthermore, the potent compounds <strong>Ⅲ20</strong>, <strong>Ⅲ22</strong>, <strong>Ⅲ24</strong>, and <strong>Ⅲ26</strong> showed low toxicity against the human hepatocyte cell line (LO2). Given these results, these isomagnolone analogues bearing <em>N</em>-(1,3-thiazol-2-yl)amides are promising antimicrobials against phytopathogenic fungi and bacteria for controlling plant diseases.</p></div>","PeriodicalId":100065,"journal":{"name":"Agriculture Communications","volume":"2 1","pages":"Article 100030"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949798124000061/pdfft?md5=e0916c84a2a2aef3740aac9d4167aeb7&pid=1-s2.0-S2949798124000061-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140123325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-situ straw return, combined with plastic film use, influences soil properties and tomato quality and yield in greenhouse conditions","authors":"Ying Han ,&nbsp;Lu Lu ,&nbsp;Lei Wang ,&nbsp;Zitong Liu ,&nbsp;Pengfei Huang ,&nbsp;Shuangchen Chen ,&nbsp;Yansu Li ,&nbsp;Mintao Sun ,&nbsp;Chaoxing He ,&nbsp;Jun Wang ,&nbsp;Yan Yan","doi":"10.1016/j.agrcom.2024.100028","DOIUrl":"10.1016/j.agrcom.2024.100028","url":null,"abstract":"<div><p>To address the challenge of disposing vegetable waste in greenhouses while mitigating white pollution associated with the use of conventional polyethylene film, we compared polyethylene (PE) film with two types of fully biodegradable film in both straw-return and no-straw-return treatments. We systematically investigated the effects of mulching on soil properties, film degradation, and tomato quality and yield. The results showed that the humic acid biodegradable film with straw-return (FZS-SR) increased the contents of lycopene, vitamin C (Vc), and soluble sugars in tomato fruit by 20.77%, 16.68%, and 25.89%, respectively, and decreased the total acid content by 8.46% compared to polyethylene film with no-straw-return (PE-NR). Additionally, FZS-SR enhanced the relative abundance of soil bacteria and fungi in Chloroflexi and Basidiomycota, while reducing the relative abundance of pathogenic fungal groups. Moreover, the biodegradable film degraded 15 days earlier in the straw-return treatment, with significantly higher characteristic peaks in Fourier transform infrared spectral analysis compared to no straw-return treatment. In a greenhouse, the straw-return model accelerated the degradation rate of biodegradable film. In summary, our results indicate that using humic acid biodegradable film with straw-return is an effective and sustainable cultivation method, improving tomato quality and yield. This approach offers insights for addressing residual plant and film pollution in vegetable production.</p></div>","PeriodicalId":100065,"journal":{"name":"Agriculture Communications","volume":"2 1","pages":"Article 100028"},"PeriodicalIF":0.0,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949798124000048/pdfft?md5=c8eb541311ded978fd04f039121f7685&pid=1-s2.0-S2949798124000048-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139889754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic resistant bacteria in food systems: Current status, resistance mechanisms, and mitigation strategies","authors":"Samuel Ariyo Okaiyeto ,&nbsp;Parag Prakash Sutar ,&nbsp;Chang Chen ,&nbsp;Jia-Bao Ni ,&nbsp;Jun Wang ,&nbsp;Arun S. Mujumdar ,&nbsp;Jing-Shou Zhang ,&nbsp;Ming-Qiang Xu ,&nbsp;Xiao-Ming Fang ,&nbsp;Chunjiang Zhang ,&nbsp;Hong-Wei Xiao","doi":"10.1016/j.agrcom.2024.100027","DOIUrl":"10.1016/j.agrcom.2024.100027","url":null,"abstract":"<div><p>The pervasive use of antibiotics in agriculture and animal husbandry has raised a significant concern—residual antibiotic contamination in food, which contributes to the natural evolution of antibiotic resistance in pathogenic microbial strains. The emergence of antibiotic resistance in microbial communities poses a global threat to food safety and security. Recently, the situation has been exacerbated by the discovery of novel strains of antibiotic resistant bacteria (ARB) in plant- and animal-derived foods. These microbes can enter the human body through direct contact with affected animals or through consumption of contaminated foods. In this review, we explore the prevalence of antibiotic contaminants in food at various locations around the world, delve into the molecular mechanisms behind acquisition of antimicrobial resistance, examine the current strategies employed to mitigate the evolution and spread of antibiotic resistant pathogens, and discuss emerging technologies aimed at halting the trend that projects 10 million annual deaths by 2050 as a result of ARB contamination in agriculture. Genetic processes, including mutations, efflux pump activity, and horizontal gene transfer, play crucial roles in the evolution and widespread distribution of ARB in the microbial community. Effectively addressing this global threat requires development of methodologies to rapidly detect ARB in the food supply chain. Therefore, we examine several established rapid diagnostic techniques such as the Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) methodology, aptasensors, and fluorescence-based Metal Organic Frameworks. Additionally, we explore innovative strategies to fight ARB such as nano-antibiotics, natural antibiotics, synthetic biology, bacteriophages, and predator bacteria. Here, we propose emerging technologies such as omics technologies and biochar use as potential tools for combating ARB. We anticipate that this review article will serve as a valuable resource for future research, particularly in the development of strategies designed not only to suppress the activities of antibiotic resistance genes but also to potentially reverse resistance mechanisms that are already widespread in microbial communities.</p></div>","PeriodicalId":100065,"journal":{"name":"Agriculture Communications","volume":"2 1","pages":"Article 100027"},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949798124000036/pdfft?md5=6b6e9fe7078b03f61886753775524178&pid=1-s2.0-S2949798124000036-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139822757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic Resistant Bacteria in Food Systems: Current Status, Resistance Mechanisms, and Mitigation Strategies","authors":"S. A. Okaiyeto, P. P. Sutar, Chang Chen, Jia Ni, Jun Wang, Arun S. Mujumdar, Jing-Shou Zhang, Ming-Qiang Xu, Xiao-Ming Fang, Chunjiang Zhang, Hong-Wei Xiao","doi":"10.1016/j.agrcom.2024.100027","DOIUrl":"https://doi.org/10.1016/j.agrcom.2024.100027","url":null,"abstract":"","PeriodicalId":100065,"journal":{"name":"Agriculture Communications","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139882715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-situ Straw Return, Combined with Plastic Film use, Influences Soil Properties and Tomato Quality and Yield in Greenhouse Conditions","authors":"Ying Han, Lu Lu, Lei Wang, Zitong Liu, Pengfei Huang, Shuangchen Chen, Yansu Li, Mintao Sun, Chaoxing He, Jun Wang, Yanhong Yan","doi":"10.1016/j.agrcom.2024.100028","DOIUrl":"https://doi.org/10.1016/j.agrcom.2024.100028","url":null,"abstract":"","PeriodicalId":100065,"journal":{"name":"Agriculture Communications","volume":"46 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139829694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-cell transcriptional profiling of porcine muscle satellite cells and myoblasts during myogenesis","authors":"Xu-dong Yi,&nbsp;He Yu,&nbsp;Rui Li,&nbsp;Tian-tian Zhao,&nbsp;Zhao-zhao He,&nbsp;Wei-jun Pang","doi":"10.1016/j.agrcom.2024.100026","DOIUrl":"10.1016/j.agrcom.2024.100026","url":null,"abstract":"<div><p>Here, we unravel the transcriptional mechanisms that govern porcine muscle myogenesis, a crucial aspect of pork production. Through single cell RNA-sequencing of <em>longissimus dorsi</em> (LD) muscle from 3-day-old piglets, we delineated 5 major cell types from 14,002 cells—muscle cells, fibro-adipogenic progenitors, mural cells, endothelial cells, and immune cells. Within the muscle cell clusters, we specifically identified muscle satellite cells and myoblasts, with 5,388 differentially expressed genes distinguishing the cell populations. Furthermore, our investigation led to the identification of novel cell surface markers for porcine muscle satellite cells, namely <em>ITGA7</em>, <em>SDC2</em>, and <em>SDC4</em>. In addition, we found 55 transcription factors, including <em>AHCTF1</em>, <em>CEBPD</em>, and <em>MAX</em>, which contribute to the regulation of muscle development. Through predictive receptor–ligand analysis, we uncovered 16 secretory factors with associated cellular communication channels influencing porcine skeletal muscle development. Notably, we identified the secretory factor ANGPTL4 as an inhibitor of porcine muscle satellite cell proliferation and differentiation, and confirmed its function through the <em>in vitro</em> treatment of cell lines. We propose that ANGTPL4 is a potential target for the treatment of myopathy. Taken together, our findings contribute to the identification and characterization of myogenic genes and regulatory networks, which enhances our understanding of porcine muscle satellite cell myogenesis and offers potential avenues for optimizing pork production.</p></div>","PeriodicalId":100065,"journal":{"name":"Agriculture Communications","volume":"2 1","pages":"Article 100026"},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949798124000024/pdfft?md5=e021a94984b15e595b9ddba783417dd8&pid=1-s2.0-S2949798124000024-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139638099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and identification of Rhizopus arrhizus causing postharvest bulb rot in Lilium davidii var. unicolor and its biocontrol using the endophytic bacterium Bacillus siamensis B55","authors":"Junlian Gao ,&nbsp;Mingfang Zhang ,&nbsp;Jiahui Liang ,&nbsp;Deli Wen ,&nbsp;Ting Liu ,&nbsp;Yuchen Sun ,&nbsp;Xiuhai Zhang ,&nbsp;Yunpeng Du","doi":"10.1016/j.agrcom.2024.100025","DOIUrl":"10.1016/j.agrcom.2024.100025","url":null,"abstract":"<div><p>Postharvest diseases in lily plants are prevalent during storage and transportation, leading to potentially catastrophic economic losses for the lily industry. Specifically, bulb rot has been observed in Lanzhou lily (<em>Lilium davidii</em> var. <em>unicolor</em>) during cold storage in Beijing, China. In this study, fungal isolates were obtained from decayed bulbs using a conventional fungal separation method, and these isolates were confirmed to be the causative agent of lily bulb rot, according to Koch postulates. A representative isolate, LZ-3-10, was selected for further identification. Based on morphological features and internal transcribed spacer sequencing results, the LZ-3-10 isolate was identified as <em>Rhizopus arrhizus</em>. Subsequently, an endophytic bacterial strain exhibiting robust antagonistic ability, <em>Bacillus siamensis</em> B55, was screened from the roots of lily plants. Evaluation of its biocontrol ability revealed that strain B55 could effectively protect <em>L. davidii</em> var. <em>unicolor</em> bulbs from infection by LZ-3-10, demonstrating a biocontrol efficacy of 51.2 ​% and significantly reducing the severity of lily <em>Rhizopus</em> rot. In summary, this study identifies <em>R. arrhizus</em> as the cause of postharvest bulb rot in <em>L. davidii</em> var. <em>unicolor</em> and, for the first time, showcases the biocontrol activity of the endophytic bacterial strain <em>B. siamensis</em> B55 against the isolated pathogenic fungus. These findings not only provide insights into lily bulb rot but also highlight the potential of <em>B. siamensis</em> B55 as a biocontrol agent for managing this disease during postharvest storage.</p></div>","PeriodicalId":100065,"journal":{"name":"Agriculture Communications","volume":"2 1","pages":"Article 100025"},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949798124000012/pdfft?md5=19b78f9d9698de14cb31e33797888589&pid=1-s2.0-S2949798124000012-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139540476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fostering sustainable banana cultivation: Maximizing red soil performance with lignin-based humic acid liquid fertilizer","authors":"Jiamin Liang ,&nbsp;Pengju Huo ,&nbsp;Xiao Mo ,&nbsp;Lidan Zhang ,&nbsp;Xiaolin Fan ,&nbsp;Shaolong Sun","doi":"10.1016/j.agrcom.2023.100018","DOIUrl":"https://doi.org/10.1016/j.agrcom.2023.100018","url":null,"abstract":"<div><p>A novel lignin-based humic acid liquid fertilizer (LHF) was prepared by supplementing traditional humic acid fertilizer with lignin. The impact of LHF treatments in two distinct red soils was assessed through examination of soil nutrient content, enzyme activity, microbial abundance, and banana biomass. Compared to the conventional composite liquid fertilizer (CF) treatment, LHF treatment improved soil nutrients, including ammonium nitrogen, nitrate nitrogen, available nitrogen, available phosphorus, and organic matter. These improvements correlated with shifts in enzymatic activities and increases in microbial populations. The LHF treatments significantly promoted nutrient uptake in banana seedlings, and consequently, accelerated growth. This system allowed for precise determination of correlations between soil physicochemical properties and soil microorganisms, increasing our fundamental understanding of the impact of soil fertilization on microbial communities. The integration of lignin into liquid fertilizers represents a step forward in the research and development of high-efficiency fertilizers. Through the improvement of soil fertility and nutrient uptake, lignin application has the potential to significantly contribute to the advancement of sustainable agriculture.</p></div>","PeriodicalId":100065,"journal":{"name":"Agriculture Communications","volume":"1 2","pages":"Article 100018"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949798123000182/pdfft?md5=8ff021180311d7b1b56319d19967fc20&pid=1-s2.0-S2949798123000182-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138467411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro gastrointestinal digestibility and peptidomic analysis of frankfurters as influenced by different forms of κ-carrageenan","authors":"Xin Li ,&nbsp;Yining Xu ,&nbsp;Baohua Kong ,&nbsp;Fangda Sun ,&nbsp;Haotian Liu ,&nbsp;Hongwei Zhang ,&nbsp;Qian Liu ,&nbsp;Chuanai Cao","doi":"10.1016/j.agrcom.2023.100017","DOIUrl":"https://doi.org/10.1016/j.agrcom.2023.100017","url":null,"abstract":"<div><p>We used peptide profiling to investigate the effects of different forms of <em>κ</em>-carrageenan (a typical hydrocolloid) on the <em>in vitro</em> gastrointestinal digestibility of frankfurters. All incorporated forms of <em>κ</em>-carrageenan were found to decrease the digestibility of meat proteins in the frankfurters, although the effects varied for some peptide fragments. Particle size analysis and super-resolution microscopy revealed that addition of <em>κ</em>-carrageenan in a water suspension resulted in the lowest protein digestibility for frankfurters, followed by <em>κ</em>-carrageenan in a powder form and in a brine suspension. Peptide profiling identified 63 peptides common to all frankfurters after gastrointestinal digestion. In addition, 9 new peptide fragments related to myofibrillar proteins and sarcoplasmic proteins were observed in digestion products from frankfurters that contained <em>κ</em>-carrageenan. Addition of the <em>κ</em>-carrageenan water suspension resulted in a unique pattern of peptide abundance after gastrointestinal digestion of the frankfurters. This pattern was not observed with the powder or brine suspension, both of which contained higher abundances of myosin peptides. However, it is still unclear how different forms of <em>κ</em>-carrageenan caused changes in specific digestion sites, and further investigation is needed to understand this phenomenon. These findings provide novel insights into the effects of various forms of <em>κ</em>-carrageenan on the digestibility of meat proteins in emulsified meat products.</p></div>","PeriodicalId":100065,"journal":{"name":"Agriculture Communications","volume":"1 2","pages":"Article 100017"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949798123000170/pdfft?md5=9a46bf17e63c2a8fee2946838fdb4aca&pid=1-s2.0-S2949798123000170-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138467435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic linkage between swimming performance and disease resistance enables multitrait breeding strategies in large yellow croaker","authors":"Junjia Zeng ,&nbsp;Ji Zhao ,&nbsp;Jiaying Wang ,&nbsp;Yuling Bai ,&nbsp;Feng Long ,&nbsp;Yacheng Deng ,&nbsp;Pengxin Jiang ,&nbsp;Junzhu Xiao ,&nbsp;Ang Qu ,&nbsp;Baichuan Tong ,&nbsp;Mei Wang ,&nbsp;Wei Liu ,&nbsp;Fei Pu ,&nbsp;Yaxian Li ,&nbsp;Peng Xu","doi":"10.1016/j.agrcom.2023.100019","DOIUrl":"https://doi.org/10.1016/j.agrcom.2023.100019","url":null,"abstract":"<div><p>Improving the robustness of fish stock has become a key issue in the advancement of aquaculture, as diseases and harsh aquatic conditions impact industry sustainability and yield. In this study, we identify several genetic loci that link swimming performance to disease resistance in large yellow croaker, and apply genomic selection (GS) for swimming performance to generate offspring with both enhanced swimming performance and disease resistance. First, we classified our reference population as superior swimmers (SS) or inferior swimmers (IS) by swimming tests and assessed inherent disease resistance. Consistent with previous research, SS displayed enhanced resistance to the parasite <em>Cryptocaryon irritans</em>. Through genotyping of parental reference and candidate populations, we generated a single nucleotide polymorphism (SNP) database, containing 45832 high-quality SNPs in total. We applied multitrait genome-wide association study analysis of swimming performance and disease resistance to this dataset and identified three linked SNPs, which were associated with 48 potential candidate genes, including <em>pp3r1b</em>, <em>mapk12b</em>, <em>mapk11</em>, and <em>tnfrsf11a</em>. Next, we generated a GS model using the BayesB method and calculated the candidate population's genetic estimated breeding value (GEBV). Individuals with GEBV's in the top 12 ​% were selected as broodstocks for breeding selective lines (SL), and the remaining individuals were used as the control group (CG). We found that SL exhibited both increased swimming performance and resistance to <em>C. irritans</em> compared to CG. Our study reveals the genetic basis related to swimming performance and disease resistance. This work has implications for designing multitrait breeding strategies and improving whole-fish fitness, both of which are critical in aquaculture.</p></div>","PeriodicalId":100065,"journal":{"name":"Agriculture Communications","volume":"1 2","pages":"Article 100019"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949798123000194/pdfft?md5=856bf60d1227eea748bda6a99cd3af3a&pid=1-s2.0-S2949798123000194-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138467436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}