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ESCRT disruption provides evidence against transsynaptic signaling functions for extracellular vesicles. ESCRT中断为突触外泌体的信号功能提供了证据。
Chemical and Petroleum Engineering Pub Date : 2024-05-05 DOI: 10.1101/2023.04.22.537920
Erica C Dresselhaus, Kathryn P Harris, Cassandra R Blanchette, Kate Koles, Steven J Del Signore, Matthew F Pescosolido, Biljana Ermanoska, Mark Rozencwaig, Rebecca C Soslowsky, Michael J Parisi, Bryan A Stewart, Timothy J Mosca, Avital A Rodal
{"title":"ESCRT disruption provides evidence against transsynaptic signaling functions for extracellular vesicles.","authors":"Erica C Dresselhaus, Kathryn P Harris, Cassandra R Blanchette, Kate Koles, Steven J Del Signore, Matthew F Pescosolido, Biljana Ermanoska, Mark Rozencwaig, Rebecca C Soslowsky, Michael J Parisi, Bryan A Stewart, Timothy J Mosca, Avital A Rodal","doi":"10.1101/2023.04.22.537920","DOIUrl":"10.1101/2023.04.22.537920","url":null,"abstract":"<p><p>Extracellular vesicles (EVs) are released by many cell types including neurons, carrying cargoes involved in signaling and disease. It is unclear whether EVs promote intercellular signaling or serve primarily to dispose of unwanted materials. We show that loss of multivesicular endosome-generating ESCRT (endosomal sorting complex required for transport) machinery disrupts release of EV cargoes from <i>Drosophila</i> motor neurons. Surprisingly, ESCRT depletion does not affect the signaling activities of the EV cargo Synaptotagmin-4 (Syt4) and disrupts only some signaling activities of the EV cargo Evenness Interrupted (Evi). Thus, these cargoes may not require intercellular transfer via EVs, and instead may be conventionally secreted or function cell autonomously in the neuron. We find that EVs are phagocytosed by glia and muscles, and that ESCRT disruption causes compensatory autophagy in presynaptic neurons, suggesting that EVs are one of several redundant mechanisms to remove cargoes from synapses. Our results suggest that synaptic EV release serves primarily as a proteostatic mechanism for certain cargoes.</p>","PeriodicalId":9748,"journal":{"name":"Chemical and Petroleum Engineering","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11092503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73196410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-Diodeness Vortex Hydrodiode 高二极管涡旋水二极管
Chemical and Petroleum Engineering Pub Date : 2023-11-14 DOI: 10.1007/s10556-023-01248-8
E. A. Pavlyuchenko, S. Yu. Kaigorodov, V. E. Shcherba
{"title":"High-Diodeness Vortex Hydrodiode","authors":"E. A. Pavlyuchenko, S. Yu. Kaigorodov, V. E. Shcherba","doi":"10.1007/s10556-023-01248-8","DOIUrl":"https://doi.org/10.1007/s10556-023-01248-8","url":null,"abstract":"","PeriodicalId":9748,"journal":{"name":"Chemical and Petroleum Engineering","volume":"21 20","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134991225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive Assessment of Pulsation Phenomena and Dynamic Loads in the Working Elements of a Hydraulic Drive 液压传动工作元件脉动现象及动载荷的综合评估
Chemical and Petroleum Engineering Pub Date : 2023-11-14 DOI: 10.1007/s10556-023-01246-w
A. V. Grigoriev, E. A. Pavlyuchenko, S. Yu. Kaigorodov, K. N. Sokirko
{"title":"Comprehensive Assessment of Pulsation Phenomena and Dynamic Loads in the Working Elements of a Hydraulic Drive","authors":"A. V. Grigoriev, E. A. Pavlyuchenko, S. Yu. Kaigorodov, K. N. Sokirko","doi":"10.1007/s10556-023-01246-w","DOIUrl":"https://doi.org/10.1007/s10556-023-01246-w","url":null,"abstract":"","PeriodicalId":9748,"journal":{"name":"Chemical and Petroleum Engineering","volume":"6 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136228719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting the Service Life of Cylinder-Piston Seals of Reciprocating Compressors 往复式压缩机缸-活塞密封寿命预测
Chemical and Petroleum Engineering Pub Date : 2023-11-13 DOI: 10.1007/s10556-023-01235-z
R. E. Kobylskiy, S. S. Busarov
{"title":"Predicting the Service Life of Cylinder-Piston Seals of Reciprocating Compressors","authors":"R. E. Kobylskiy, S. S. Busarov","doi":"10.1007/s10556-023-01235-z","DOIUrl":"https://doi.org/10.1007/s10556-023-01235-z","url":null,"abstract":"","PeriodicalId":9748,"journal":{"name":"Chemical and Petroleum Engineering","volume":"46 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136346381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Heat-Transfer Energy Efficiency for Direct and Swirl Pipe Flows 直流和旋流管道传热效率的比较
Chemical and Petroleum Engineering Pub Date : 2023-11-13 DOI: 10.1007/s10556-023-01242-0
Yu. Ya. Pechenegov
{"title":"Comparison of Heat-Transfer Energy Efficiency for Direct and Swirl Pipe Flows","authors":"Yu. Ya. Pechenegov","doi":"10.1007/s10556-023-01242-0","DOIUrl":"https://doi.org/10.1007/s10556-023-01242-0","url":null,"abstract":"","PeriodicalId":9748,"journal":{"name":"Chemical and Petroleum Engineering","volume":"48 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136346375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of the Chemical Composition of Steel on the Heat Resistance of a Surface Layer Subjected to Combined Hardening Treatment with Electromechanical Treatment + Surface Plastic Deformation 钢的化学成分对机械硬化+表面塑性变形复合处理表层耐热性的影响
Chemical and Petroleum Engineering Pub Date : 2023-11-13 DOI: 10.1007/s10556-023-01236-y
N. G. Dudkina, I. N. Zakharov, V. V. Barinov
{"title":"Influence of the Chemical Composition of Steel on the Heat Resistance of a Surface Layer Subjected to Combined Hardening Treatment with Electromechanical Treatment + Surface Plastic Deformation","authors":"N. G. Dudkina, I. N. Zakharov, V. V. Barinov","doi":"10.1007/s10556-023-01236-y","DOIUrl":"https://doi.org/10.1007/s10556-023-01236-y","url":null,"abstract":"","PeriodicalId":9748,"journal":{"name":"Chemical and Petroleum Engineering","volume":"49 21","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134992753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Membrane Thickness on Parameters for Producing High-Purity Hydrogen from Hydrocarbon Raw Materials in Membrane-Catalytic Devices 膜厚度对膜催化装置中烃类原料制氢工艺参数的影响
Chemical and Petroleum Engineering Pub Date : 2023-11-13 DOI: 10.1007/s10556-023-01245-x
A. B. Vandyshev, V. A. Kulikov
{"title":"Effect of Membrane Thickness on Parameters for Producing High-Purity Hydrogen from Hydrocarbon Raw Materials in Membrane-Catalytic Devices","authors":"A. B. Vandyshev, V. A. Kulikov","doi":"10.1007/s10556-023-01245-x","DOIUrl":"https://doi.org/10.1007/s10556-023-01245-x","url":null,"abstract":"","PeriodicalId":9748,"journal":{"name":"Chemical and Petroleum Engineering","volume":"53 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136347623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Separating Device for Capturing Fine Particles Formed During Operation of Fluidized Bed Reactors 一种捕获流化床反应器运行过程中形成的细颗粒的分离装置
Chemical and Petroleum Engineering Pub Date : 2023-11-11 DOI: 10.1007/s10556-023-01241-1
V. E. Zinurov, A. V. Dmitriev, A. A. Abdullina, E. I. Salakhova, O. S. Dmitrieva
{"title":"Separating Device for Capturing Fine Particles Formed During Operation of Fluidized Bed Reactors","authors":"V. E. Zinurov, A. V. Dmitriev, A. A. Abdullina, E. I. Salakhova, O. S. Dmitrieva","doi":"10.1007/s10556-023-01241-1","DOIUrl":"https://doi.org/10.1007/s10556-023-01241-1","url":null,"abstract":"","PeriodicalId":9748,"journal":{"name":"Chemical and Petroleum Engineering","volume":"47 22","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135042982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Features of Localization of Sodium Hydroxide Solution Leakage Using Acoustic Emission Method 声发射法定位氢氧化钠溶液泄漏的特点
Chemical and Petroleum Engineering Pub Date : 2023-11-11 DOI: 10.1007/s10556-023-01232-2
I. A. Rastegaev, A. K. Khrustalev, I. I. Rastegaeva, P. N. Zorin
{"title":"Features of Localization of Sodium Hydroxide Solution Leakage Using Acoustic Emission Method","authors":"I. A. Rastegaev, A. K. Khrustalev, I. I. Rastegaeva, P. N. Zorin","doi":"10.1007/s10556-023-01232-2","DOIUrl":"https://doi.org/10.1007/s10556-023-01232-2","url":null,"abstract":"","PeriodicalId":9748,"journal":{"name":"Chemical and Petroleum Engineering","volume":"48 14","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135042969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mathematical Substantiation of the Monitoring of Corrosion Processes in Process Equipment by Radiometric Method 用辐射测量法监测加工设备腐蚀过程的数学证明
Chemical and Petroleum Engineering Pub Date : 2023-11-11 DOI: 10.1007/s10556-023-01233-1
V. P. Zayarnyi, Yu.V. Pastukhov, I. L. Gonik
{"title":"Mathematical Substantiation of the Monitoring of Corrosion Processes in Process Equipment by Radiometric Method","authors":"V. P. Zayarnyi, Yu.V. Pastukhov, I. L. Gonik","doi":"10.1007/s10556-023-01233-1","DOIUrl":"https://doi.org/10.1007/s10556-023-01233-1","url":null,"abstract":"","PeriodicalId":9748,"journal":{"name":"Chemical and Petroleum Engineering","volume":"31 16","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135041789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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