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Challenges and Advances in Chemical Science Vol. 6最新文献

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Investigating the Influence of pH on Drug Release from Zidovudine Matrices Containing Different Grades of Hydroxypropyl Methyl Cellulose 研究pH对含不同等级羟丙基甲基纤维素的齐多夫定基质药物释放的影响
Challenges and Advances in Chemical Science Vol. 6 Pub Date : 2021-10-23 DOI: 10.9734/bpi/cacs/v6/1927c
M. Khan
{"title":"Investigating the Influence of pH on Drug Release from Zidovudine Matrices Containing Different Grades of Hydroxypropyl Methyl Cellulose","authors":"M. Khan","doi":"10.9734/bpi/cacs/v6/1927c","DOIUrl":"https://doi.org/10.9734/bpi/cacs/v6/1927c","url":null,"abstract":"The present study examines the effect of multimedia dissolution profile on the drug release of sustained release hydrophilic matrices of zidovudine containing combination of different grades of hydroxypropyl methylcellulose. Zidovudine the first anti-HIV compound approved for clinical use is widely used for the treatment of AIDS either alone or in combination with other antiviral agents. Matrices were prepared using combination of different grades of HPMC viz, HPMCK4M and HPMCK15M to sustain the release of the drug. Multimedia dissolution studies were performed to mimic the in-vivo condition by doing in-vitro test. The pH/buffer selection is based on the exposure of drug from stomach to intestine/colon. The study ensures the impact of pH changes on dissolution and release of drug substance for absorption. Matrices also provide quite regulated release of the drug zidovudine over an extended period of time.","PeriodicalId":9701,"journal":{"name":"Challenges and Advances in Chemical Science Vol. 6","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89265807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determining the Synthesis of Pyrazoles via Multi-Component Reaction and Cyclization Cascade of Hydrazono Ugi Adducts 多组份反应及水合脲加合物环化级联合成吡唑的研究
Challenges and Advances in Chemical Science Vol. 6 Pub Date : 2021-10-23 DOI: 10.9734/bpi/cacs/v6/1988c
F. Allouche
{"title":"Determining the Synthesis of Pyrazoles via Multi-Component Reaction and Cyclization Cascade of Hydrazono Ugi Adducts","authors":"F. Allouche","doi":"10.9734/bpi/cacs/v6/1988c","DOIUrl":"https://doi.org/10.9734/bpi/cacs/v6/1988c","url":null,"abstract":"","PeriodicalId":9701,"journal":{"name":"Challenges and Advances in Chemical Science Vol. 6","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86120635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Water has the Capability of Reducing the Alcohol-Stimulative Taste of Spirits 水有降低烈酒的酒精刺激味道的能力
Challenges and Advances in Chemical Science Vol. 6 Pub Date : 2021-10-23 DOI: 10.9734/bpi/cacs/v6/4285f
Akira Nose
{"title":"Water has the Capability of Reducing the Alcohol-Stimulative Taste of Spirits","authors":"Akira Nose","doi":"10.9734/bpi/cacs/v6/4285f","DOIUrl":"https://doi.org/10.9734/bpi/cacs/v6/4285f","url":null,"abstract":"","PeriodicalId":9701,"journal":{"name":"Challenges and Advances in Chemical Science Vol. 6","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88455964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of Chemically Desposited ZnO Thin Films for Possible Device Applications 化学沉积ZnO薄膜在器件应用中的测定
Challenges and Advances in Chemical Science Vol. 6 Pub Date : 2021-10-23 DOI: 10.9734/bpi/cacs/v6/4925f
J. I. Onwuemeka, F. Eze, I. Ndukwe
{"title":"Determination of Chemically Desposited ZnO Thin Films for Possible Device Applications","authors":"J. I. Onwuemeka, F. Eze, I. Ndukwe","doi":"10.9734/bpi/cacs/v6/4925f","DOIUrl":"https://doi.org/10.9734/bpi/cacs/v6/4925f","url":null,"abstract":"","PeriodicalId":9701,"journal":{"name":"Challenges and Advances in Chemical Science Vol. 6","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79219011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determining the Properties of Phenobarbital an Antiepileptic Drug Using Chemcalise Software 用Chemcalise软件测定抗癫痫药物苯巴比妥的性质
Challenges and Advances in Chemical Science Vol. 6 Pub Date : 2021-10-23 DOI: 10.9734/bpi/cacs/v6/5051f
K. Laxmi
{"title":"Determining the Properties of Phenobarbital an Antiepileptic Drug Using Chemcalise Software","authors":"K. Laxmi","doi":"10.9734/bpi/cacs/v6/5051f","DOIUrl":"https://doi.org/10.9734/bpi/cacs/v6/5051f","url":null,"abstract":"","PeriodicalId":9701,"journal":{"name":"Challenges and Advances in Chemical Science Vol. 6","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87160648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-thermal Plasma for Coke Elimination in an Aged Hydrotreating Catalyst: Comparison with a Coked Zeolite 老化加氢处理催化剂中的非热等离子体除焦:与焦化沸石的比较
Challenges and Advances in Chemical Science Vol. 6 Pub Date : 2021-10-23 DOI: 10.9734/bpi/cacs/v6/14554d
L. Pinard, C. Batiot-Dupeyrat
{"title":"Non-thermal Plasma for Coke Elimination in an Aged Hydrotreating Catalyst: Comparison with a Coked Zeolite","authors":"L. Pinard, C. Batiot-Dupeyrat","doi":"10.9734/bpi/cacs/v6/14554d","DOIUrl":"https://doi.org/10.9734/bpi/cacs/v6/14554d","url":null,"abstract":"","PeriodicalId":9701,"journal":{"name":"Challenges and Advances in Chemical Science Vol. 6","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86927156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on Modeling with Multilayer Perceptron for Detection of Fuel Adulteration Using Python Programming 基于Python编程的多层感知器燃料掺假检测建模研究
Challenges and Advances in Chemical Science Vol. 6 Pub Date : 2021-10-23 DOI: 10.9734/bpi/cacs/v6/4828f
U. V. Babu, M. Ramakrishan, M. Nagamani
{"title":"Study on Modeling with Multilayer Perceptron for Detection of Fuel Adulteration Using Python Programming","authors":"U. V. Babu, M. Ramakrishan, M. Nagamani","doi":"10.9734/bpi/cacs/v6/4828f","DOIUrl":"https://doi.org/10.9734/bpi/cacs/v6/4828f","url":null,"abstract":"","PeriodicalId":9701,"journal":{"name":"Challenges and Advances in Chemical Science Vol. 6","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80028929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of Anti-bacterial Effect, Anti- odour Effect, uv- protection Factor and XRD on Formic Acid Treated Modal and Cotton Fabric 甲酸处理莫代尔和棉织物的抗菌、防臭、防紫外线系数和XRD测定
Challenges and Advances in Chemical Science Vol. 6 Pub Date : 2021-10-23 DOI: 10.9734/bpi/cacs/v6/5306f
K. Priya, J. Moses, T. Sasikala
{"title":"Determination of Anti-bacterial Effect, Anti- odour Effect, uv- protection Factor and XRD on Formic Acid Treated Modal and Cotton Fabric","authors":"K. Priya, J. Moses, T. Sasikala","doi":"10.9734/bpi/cacs/v6/5306f","DOIUrl":"https://doi.org/10.9734/bpi/cacs/v6/5306f","url":null,"abstract":"","PeriodicalId":9701,"journal":{"name":"Challenges and Advances in Chemical Science Vol. 6","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82018011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determining the Practical Synthesis and Purification of cis-11-Octadecenoic Acid: A Component of Inhibition of Endotoxin Response 确定顺式-11-十八烯酸的实际合成和纯化:抑制内毒素反应的成分
Challenges and Advances in Chemical Science Vol. 6 Pub Date : 2021-10-23 DOI: 10.9734/bpi/cacs/v6/5300f
Y. Yuasa
{"title":"Determining the Practical Synthesis and Purification of cis-11-Octadecenoic Acid: A Component of Inhibition of Endotoxin Response","authors":"Y. Yuasa","doi":"10.9734/bpi/cacs/v6/5300f","DOIUrl":"https://doi.org/10.9734/bpi/cacs/v6/5300f","url":null,"abstract":"","PeriodicalId":9701,"journal":{"name":"Challenges and Advances in Chemical Science Vol. 6","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75207402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural and Biocidal Studies of Monobutyltin (IV) Derivatives of 1-Hydroxy-2-Naphthoic Acid 1-羟基-2-萘酸单丁基锡衍生物的结构与杀菌研究
Challenges and Advances in Chemical Science Vol. 6 Pub Date : 2021-10-23 DOI: 10.9734/bpi/cacs/v6/5052f
P. Mittal, Manoj Kumar Pachouri
{"title":"Structural and Biocidal Studies of Monobutyltin (IV) Derivatives of 1-Hydroxy-2-Naphthoic Acid","authors":"P. Mittal, Manoj Kumar Pachouri","doi":"10.9734/bpi/cacs/v6/5052f","DOIUrl":"https://doi.org/10.9734/bpi/cacs/v6/5052f","url":null,"abstract":"","PeriodicalId":9701,"journal":{"name":"Challenges and Advances in Chemical Science Vol. 6","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74054558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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