Canadian Journal of Surgery最新文献

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Wellness interventions in surgery: a scoping review. 手术中的健康干预:范围综述。
IF 2 4区 医学
Canadian Journal of Surgery Pub Date : 2025-09-26 Print Date: 2025-09-01 DOI: 10.1503/cjs.009124
Kimberley Yuen, Olivia Ginty, Kaitlyn Rourke, Michael Hendry, Natasha Cohen, Glykeria Martou
{"title":"Wellness interventions in surgery: a scoping review.","authors":"Kimberley Yuen, Olivia Ginty, Kaitlyn Rourke, Michael Hendry, Natasha Cohen, Glykeria Martou","doi":"10.1503/cjs.009124","DOIUrl":"10.1503/cjs.009124","url":null,"abstract":"<p><strong>Background: </strong>Wellness research has expanded in surgery owing to the high prevalence of burnout. In this scoping review, we aim to identify trends of wellness interventions for surgeons and surgical trainees.</p><p><strong>Methods: </strong>We identified studies on wellness interventions across surgical specialties. We categorized interventions based on the targeted wellness domain, including physical, social, emotional, intellectual, and occupational domains.</p><p><strong>Results: </strong>We included 49 studies in the final analysis. Most focused on resident wellness (<i>n</i> = 40) and were categorized as an individual-level intervention (<i>n</i> = 21). General surgery was represented in most studies (<i>n</i> = 24). Interventions focused on ergonomics, mindfulness, stress reduction, work hours, and wellness programs. Since 2015, there has been a shift in the wellness domains addressed from physical and occupational, to mostly emotional.</p><p><strong>Conclusion: </strong>The prevalence of individual-level interventions targeting emotional wellness reflects a belief that surgeons are responsible for their own wellness. Studies to date have largely focused on surgical trainees, with a dearth of research on measures to improve staff surgeon wellness. Methodologically sound intervention studies with objective outcome measures are lacking and needed to facilitate a culture of shared organizational responsibility for surgeon well-being.</p>","PeriodicalId":9573,"journal":{"name":"Canadian Journal of Surgery","volume":"68 5","pages":"E376-E392"},"PeriodicalIF":2.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145173835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The hidden epidemiology of trauma in Nunavik: a call for a dedicated trauma registry. 努那维克隐藏的创伤流行病学:呼吁建立专门的创伤登记处。
IF 2 4区 医学
Canadian Journal of Surgery Pub Date : 2025-09-26 Print Date: 2025-09-01 DOI: 10.1503/cjs.013324
Lilly Groszman, Natasha G Caminsky, Jeremy Grushka, Larry Watt, Nathalie Boulanger, Faiz Ahmad Khan, Tarek Razek, Paola Fata, Kosar Khwaja, Dan Deckelbaum, Atif Jastaniah, Katherine McKendy, Evan G Wong
{"title":"The hidden epidemiology of trauma in Nunavik: a call for a dedicated trauma registry.","authors":"Lilly Groszman, Natasha G Caminsky, Jeremy Grushka, Larry Watt, Nathalie Boulanger, Faiz Ahmad Khan, Tarek Razek, Paola Fata, Kosar Khwaja, Dan Deckelbaum, Atif Jastaniah, Katherine McKendy, Evan G Wong","doi":"10.1503/cjs.013324","DOIUrl":"10.1503/cjs.013324","url":null,"abstract":"<p><strong>Background: </strong>Delivering trauma care in Nunavik is challenging. Despite the benefits of trauma registries, no routine data collection captures data from Nunavik patients in Quebec's provincial database. We sought to compare trauma epidemiology from data collected on site in Nunavik with data from a governmental registry at a tertiary centre, hypothesizing sufficient cohort differences to justify a dedicated registry.</p><p><strong>Methods: </strong>We conducted a retrospective review of 2 cohorts (2015 to 2019). The first cohort included patients at Kuujjuaq's Centre de santé Tulattavik de l'Ungava or Puvirnituq's Centre de santé Inuulitisivik (the Nunavik cohort) and the second cohort included patients admitted to the provincial referral centre for the Nunavimmiut at the Montreal General Hospital (MGH). Nunavik data were collected through chart review, while MGH data were obtained from the McGill University Health Centre Trauma Registry. We analyzed patient demographics, injury mechanisms, transfer characteristics, and modifiable risk factors using descriptive statistics.</p><p><strong>Results: </strong>We identified 776 patients in the Nunavik cohort, of whom 42.0% were transferred to the MGH. Of all 776 trauma patients in Nunavik, only 14.3% were captured in the trauma registry. Among those transferred to the MGH, 33.9% were recorded in the registry, highlighting a gap in data representation. Patients in the Nunavik cohort were significantly younger (30 yr v. 37 yr, <i>p</i> < 0.001) and more often female (51.0% v. 38.8%, <i>p</i> < 0.001). Mechanisms of injury and vital signs also differed significantly (<i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Data from many patients from Nunavik are not captured in the governmental database, with the trauma epidemiology in the region significantly differing from those presenting to the tertiary centre. A dedicated prospective, sustainable registry is needed to improve quality of care and outcomes in Nunavik.</p>","PeriodicalId":9573,"journal":{"name":"Canadian Journal of Surgery","volume":"68 5","pages":"E401-E409"},"PeriodicalIF":2.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145173863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A necessary paradigm shift: recognizing the surgeon-advocate in academic surgery. 一个必要的范式转变:承认外科医生在学术手术中的倡导者。
IF 2.2 4区 医学
Canadian Journal of Surgery Pub Date : 2025-09-11 Print Date: 2025-09-01 DOI: 10.1503/cjs.014224
Adom Bondzi-Simpson, Betel Yibrehu, Amanpreet K Brar, Nour Bakhache, Kennedy Ayoo, Elliott Yee, Chantal Valiquette, Tyee K Fellows, David-Dan Nguyen, Armaan K Malhotra, Najma Ahmed, Savtaj Brar
{"title":"A necessary paradigm shift: recognizing the surgeon-advocate in academic surgery.","authors":"Adom Bondzi-Simpson, Betel Yibrehu, Amanpreet K Brar, Nour Bakhache, Kennedy Ayoo, Elliott Yee, Chantal Valiquette, Tyee K Fellows, David-Dan Nguyen, Armaan K Malhotra, Najma Ahmed, Savtaj Brar","doi":"10.1503/cjs.014224","DOIUrl":"10.1503/cjs.014224","url":null,"abstract":"<p><p>Health equity and the social determinants of health are increasingly prioritized in health care delivery across North America and globally, yet academic medicine remains ill equipped to support equity-focused advocacy. We argue that this stems mainly from a gap in recognizing advocacy as an academic pillar alongside research, education, and administration. Advocacy is undervalued in academic medicine, as reflected in teaching, hiring, and promotion criteria and what is published in academic journals. Health equity is essential for the health of populations, and the current structure of academic medicine should be redesigned to recognize, value, and support equity-based advocacy efforts. Advocacy can be integrated in 2 key areas: medical education and faculty roles and promotion pathways. A new academic role, the surgeon-advocate - whose work focuses on the engagement, knowledge dissemination, and administration of advocacy-based work to affect system change - is vital for a paradigm shift that accepts advocacy into the essential work of academic medicine. The concept of a surgeon-advocate is not new and is vital to our identities as physicians. However, formally embracing advocacy within academic institutions represents the paradigm shift needed to move closer to health equity goals. This analysis proposes a critical revision to academic surgery and, more broadly, academic medicine. We provide practical steps to intentionally weave advocacy and health equity into the fabric of academic medical institutions to improve how we practise and serve our patients.</p>","PeriodicalId":9573,"journal":{"name":"Canadian Journal of Surgery","volume":"68 5","pages":"E346-E352"},"PeriodicalIF":2.2,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic literacy among surgeons who manage patients with cancer: a national survey of knowledge, perceptions, attitudes, and barriers. 治疗癌症患者的外科医生的基因素养:一项关于知识、观念、态度和障碍的全国性调查。
IF 2 4区 医学
Canadian Journal of Surgery Pub Date : 2025-09-11 Print Date: 2025-09-01 DOI: 10.1503/cjs.008424
Linda Y N Fei, Sandra Messiha, Zuhaib M Mir, Rachelle Dinchong, Alison Rusnak, Nicholas Cofie, Nancy Dalgarno, Rona E Cheifetz, Shaila J Merchant
{"title":"Genetic literacy among surgeons who manage patients with cancer: a national survey of knowledge, perceptions, attitudes, and barriers.","authors":"Linda Y N Fei, Sandra Messiha, Zuhaib M Mir, Rachelle Dinchong, Alison Rusnak, Nicholas Cofie, Nancy Dalgarno, Rona E Cheifetz, Shaila J Merchant","doi":"10.1503/cjs.008424","DOIUrl":"10.1503/cjs.008424","url":null,"abstract":"<p><strong>Background: </strong>The rapid evolution of genetic testing and availability of information has necessitated increased surgeon participation in genetics-related tasks. We sought to characterize knowledge, perceptions, attitudes, and barriers pertaining to genetic literacy among Canadian surgeons who manage patients with a hereditary predisposition to or confirmed cancer.</p><p><strong>Methods: </strong>We distributed a Web-based survey to surgeons across Canada from June to December 2023 through relevant surgical societies. We analyzed quantitative and narrative data from the survey descriptively and thematically.</p><p><strong>Results: </strong>We included 57 participants from 8 provinces (response rate 10%). Many surgeons (28/45, 62%) reported performing risk assessment, but 16% (7/45) reported counselling and 29% (13/45) reported ordering genetic testing. Surgeons reported low confidence in ordering testing and in interpreting and discussing implications of testing results. Most surgeons (35/39, 90%) expressed a desire for improvement in their knowledge and in their confidence in hereditary cancer genetics. Approval and funding for testing, referral to a genetic counsellor or medical geneticist, and availability of genetics clinics were reported as extreme barriers to providing care.</p><p><strong>Conclusion: </strong>Practising surgeons in Canada participate in many genetics-related tasks, but they report low confidence and face barriers to genetic literacy. There is a need and desire for interventions targeting genetic literacy among surgeons in Canada.</p>","PeriodicalId":9573,"journal":{"name":"Canadian Journal of Surgery","volume":"68 5","pages":"E337-E345"},"PeriodicalIF":2.0,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
L’introduction des dispositifs médicaux modernes entraîne-t-elle un problème de sécurité? 引进现代医疗设备会带来安全问题吗?
IF 2.2 4区 医学
Canadian Journal of Surgery Pub Date : 2025-08-08 Print Date: 2025-07-01 DOI: 10.1503/cjs.014425
Chad G Ball, Edward J Harvey, Andrew W Kirkpatrick
{"title":"L’introduction des dispositifs médicaux modernes entraîne-t-elle un problème de sécurité?","authors":"Chad G Ball, Edward J Harvey, Andrew W Kirkpatrick","doi":"10.1503/cjs.014425","DOIUrl":"10.1503/cjs.014425","url":null,"abstract":"","PeriodicalId":9573,"journal":{"name":"Canadian Journal of Surgery","volume":"68 4","pages":"E335-E336"},"PeriodicalIF":2.2,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Canadian considerations on updating the age of initiation for colorectal cancer screening in individuals at average risk. 加拿大对平均风险个体更新结直肠癌筛查起始年龄的考虑。
IF 2 4区 医学
Canadian Journal of Surgery Pub Date : 2025-08-08 Print Date: 2025-07-01 DOI: 10.1503/cjs.000825
Samuel Lamarre Skulsky, Eisar Al-Sukhni, Roselyne Villiard, Ting Li, Mo Yu Li, Jerry T Dang
{"title":"Canadian considerations on updating the age of initiation for colorectal cancer screening in individuals at average risk.","authors":"Samuel Lamarre Skulsky, Eisar Al-Sukhni, Roselyne Villiard, Ting Li, Mo Yu Li, Jerry T Dang","doi":"10.1503/cjs.000825","DOIUrl":"10.1503/cjs.000825","url":null,"abstract":"<p><p>The incidence of early-onset colorectal cancer (CRC), defined as CRC occurring in individuals younger than 50 years, is increasing globally. Emerging evidence suggests that the incidence and prevalence of CRC in individuals aged 45-49 years approach those in individuals aged 50-59 years. To address this concerning trend, many health care systems and clinical specialist societies are advocating for lowering the age of initiation for CRC screening in individuals at average risk to 45 years. The present review, provided by the Canadian Association of General Surgeons Clinical Practice Committee, gives an overview of the current CRC screening guidelines in Canada, the rationale for earlier screening, and the challenges and impact of lowering the screening age to 45 years to health care systems in Canada.</p>","PeriodicalId":9573,"journal":{"name":"Canadian Journal of Surgery","volume":"68 4","pages":"E313-E324"},"PeriodicalIF":2.0,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do we have a safety issue with the introduction of modern medical devices? 引进现代医疗设备是否存在安全问题?
IF 2.2 4区 医学
Canadian Journal of Surgery Pub Date : 2025-08-08 Print Date: 2025-07-01 DOI: 10.1503/cjs.013825
Chad G Ball, Edward J Harvey, Andrew W Kirkpatrick
{"title":"Do we have a safety issue with the introduction of modern medical devices?","authors":"Chad G Ball, Edward J Harvey, Andrew W Kirkpatrick","doi":"10.1503/cjs.013825","DOIUrl":"10.1503/cjs.013825","url":null,"abstract":"","PeriodicalId":9573,"journal":{"name":"Canadian Journal of Surgery","volume":"68 4","pages":"E333-E334"},"PeriodicalIF":2.2,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Matching males and females undergoing Shouldice repair using a prospective, longitudinal design. 采用前瞻性纵向设计匹配接受肩部修复的男性和女性。
IF 2 4区 医学
Canadian Journal of Surgery Pub Date : 2025-08-08 Print Date: 2025-07-01 DOI: 10.1503/cjs.012824
Marguerite Mainprize, Anton Svendrovski, Christoph Paasch, Ayse Yilbas, Joel Katz
{"title":"Matching males and females undergoing Shouldice repair using a prospective, longitudinal design.","authors":"Marguerite Mainprize, Anton Svendrovski, Christoph Paasch, Ayse Yilbas, Joel Katz","doi":"10.1503/cjs.012824","DOIUrl":"10.1503/cjs.012824","url":null,"abstract":"<p><strong>Background: </strong>Sex differences in chronic postsurgical pain have been reported, with the main findings indicating that females experience a greater incidence and severity of pain than males; however, it remains unclear to what these sex differences are attributable. We sought to compare pain and related psychological factors between a matched sample of male and female patients 3 months and 1 year after Shouldice repair.</p><p><strong>Methods: </strong>Male and female participants who underwent Shouldice repair were manually matched 1:1 and compared on 10 variables: age, body mass index, smoking status, preoperative depression and anxiety scores, living status (alone or with others), American Society of Anesthesiologists physical status health classification, preoperative chronic pain, preoperative hernia pain, preoperative pain catastrophizing scores, and nerve handling during surgery. Data on pain were collected from questionnaires administered 3 months and 1 year postoperatively, and data on participant clinical characteristics were collected from operative notes and patient charts.</p><p><strong>Results: </strong>There were 28 matched male-female pairs at 3 months and 21 at 1 year. The average age preoperatively was 56.18 ± 12.48 years. At 3 months postoperative, 18 females and 6 males had pain (<i>p</i> = 0.001), with females reporting more frequent (<i>p</i> = 0.004) and longer durations (<i>p</i> = 0.005) of pain. The 3-month postoperative Brief Pain Inventory Numeric Rating Scale scores (0-10) showed that in terms of pain severity, females had higher \"worst pain\" (1.61 ± 1.85 v. 0.32 ± 0.77, <i>p</i> = 0.002), \"average pain\" (0.86 ± 1.08 v. 0.14 ± 0.45, <i>p</i> = 0.002), and \"pain now\" (0.43 ± 1.20 v. 0 ± 0, <i>p</i> = 0.010) scores than males. Significant differences were not found in the incidence, severity, frequency, or duration of pain between females and males at 1 year.</p><p><strong>Conclusion: </strong>After matching on important confounders, sex differences were found in pain frequency, duration, incidence, and severity at 3 months after Shouldice repair. However, by 1 year after surgery the differences were no longer significant.</p><p><strong>Trial registration: </strong>Clinicaltrials.gov # NCT03986060.</p>","PeriodicalId":9573,"journal":{"name":"Canadian Journal of Surgery","volume":"68 4","pages":"E325-E332"},"PeriodicalIF":2.0,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 25-year retrospective of Canadian plastic surgery research and its influence: a bibliometric study. 加拿大整形外科研究25年回顾及其影响:文献计量学研究。
IF 2 4区 医学
Canadian Journal of Surgery Pub Date : 2025-07-15 Print Date: 2025-07-01 DOI: 10.1503/cjs.012024
Daniel Josué Guerra Ordaz, Peter Tai, Antoine Lalonde, Magdalena Cordoba, Éolie Delisle, Sophie Nguyen, Rocío Branes, Maryam Mozafarinia, Carlos Cordoba
{"title":"A 25-year retrospective of Canadian plastic surgery research and its influence: a bibliometric study.","authors":"Daniel Josué Guerra Ordaz, Peter Tai, Antoine Lalonde, Magdalena Cordoba, Éolie Delisle, Sophie Nguyen, Rocío Branes, Maryam Mozafarinia, Carlos Cordoba","doi":"10.1503/cjs.012024","DOIUrl":"10.1503/cjs.012024","url":null,"abstract":"<p><strong>Background: </strong>Bibliometric analysis is a research tool for evaluating and analyzing scholarly output and impact within a specific domain. This study aimed to assess the quantity and quality of plastic surgery research conducted by Canadian-affiliated authors from 1999 to 2023.</p><p><strong>Methods: </strong>We conducted a comprehensive bibliometric analysis using the Web of Science Core Collection to retrieve data from 60 leading plastic surgery journals, focusing on original articles and reviews published between 1999 and 2023. The InCites Benchmarking & Analytics platform evaluated the publications' quantity and quality. Quality assessment employed 2 key metrics:: category-normalized citation impact (CNCI) and the percentage of publications in the top quartile of journals (%Q1) based on impact factors. We used VOSviewer to map collaborative relationships among universities over various periods.</p><p><strong>Results: </strong>Canada ranked as the 11th leading contributor globally, with 4446 publications. Nationally, the University of Toronto accounted for more than 30% of Canadian contributions. In terms of quality, Canada led with a CNCI of 1.09 and 21% of publications in the %Q1. Within Canada, McMaster University had the highest CNCI at 1.33, while Dalhousie University ranked highest in %Q1 at 32.3%. Our VOSviewer map of institutional collaborations revealed increased cooperation between Canadian universities and international institutions over the last 25 years.</p><p><strong>Conclusion: </strong>Over the last 25 years, the trajectory of Canadian plastic surgery literature has been characterized by continuous expansion while maintaining high quality. Efforts should be made to continue to increase the quality and quantity of Canadian research while sustaining international collaborations.</p>","PeriodicalId":9573,"journal":{"name":"Canadian Journal of Surgery","volume":"68 4","pages":"E296-E304"},"PeriodicalIF":2.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between preoperative proton pump inhibitor use and postoperative infectious and renal complications following major elective surgery. 术前使用质子泵抑制剂与重大择期手术后感染和肾脏并发症的关系。
IF 2 4区 医学
Canadian Journal of Surgery Pub Date : 2025-07-15 Print Date: 2025-07-01 DOI: 10.1503/cjs.010224
Luc Dubois, J Andrew McClure, Philip M Jones, Marko Mrkobrada, Suzanne Flier, Blayne Welk, Kelly Vogt
{"title":"Association between preoperative proton pump inhibitor use and postoperative infectious and renal complications following major elective surgery.","authors":"Luc Dubois, J Andrew McClure, Philip M Jones, Marko Mrkobrada, Suzanne Flier, Blayne Welk, Kelly Vogt","doi":"10.1503/cjs.010224","DOIUrl":"10.1503/cjs.010224","url":null,"abstract":"<p><strong>Background: </strong>Use of poton pump inhibitors (PPIs) is associated with increased risk of <i>Clostridioides difficile</i>-associated colitis, pneumonia, and acute kidney injury. Their effect on postoperative complications is unknown. The objective of this study was to investigate the association between PPIs and the risk of <i>C. difficile</i>-associated colitis, pneumonia, and acute kidney injury following elective surgery.</p><p><strong>Methods: </strong>In this population-based, matched cohort study, we identified patients who had filled a PPI prescription within 90 days before major elective surgery (2010-2019). Study outcomes included <i>C. difficile</i>-associated colitis, pneumonia, acute kidney injury, gastrointestinal bleeding, and death within 90 days of surgery. We matched patients 1-to-1 on the basis of age, sex, procedure, date of surgery, and a propensity score predicting PPI exposure. We used logistic regression to evaluate between-group differences.</p><p><strong>Results: </strong>Of 313 163 patients, 89 047 (28.4%) used PPIs; of those, 79 681 were successfully matched to patients who did not use PPIs. The risk of the composite outcome (acute kidney injury, pneumonia, <i>C. difficile</i>-associated colitis, and death) among the patients who used PPIs was slightly higher than among the patients who did not use PPIs (10.6% v. 10.2 4%), and was driven primarily by a higher rate of pneumonia among those who used PPIs (4.0% v. 3.7%). There was a lower rate of gastrointestinal bleeding among the patients who used PPIs (1.6% v. 1.8%). The risk of pneumonia was most pronounced in the subgroup undergoing hip and knee replacement (odds ratio 1.21, 95% confidence interval 1.08-1.36; <i>p</i> = 0.001). There were no significant differences between groups with regard to rates of <i>C. difficile</i>-associated colitis or acute kidney injury.</p><p><strong>Conclusion: </strong>We found that preoperative PPI use was associated with higher rates of pneumonia, particularly among patients undergoing hip and knee replacement surgery, and lower rates of gastrointestinal bleeding. Patients taking a PPI before surgery should be targeted for therapies aimed at reducing pneumonia risk, such as aggressive chest physiotherapy, following their operation.</p>","PeriodicalId":9573,"journal":{"name":"Canadian Journal of Surgery","volume":"68 4","pages":"E305-E312"},"PeriodicalIF":2.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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