Cancer Radiotherapie最新文献

{"title":"Cancer Radiothérapie reviewers in 2025","authors":"","doi":"10.1016/j.canrad.2026.104820","DOIUrl":"10.1016/j.canrad.2026.104820","url":null,"abstract":"","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"30 1","pages":"Article 104820"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147858140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technological innovations in head and neck radiotherapy: What does the future hold?","authors":"Anouchka Modesto ,&nbsp;Pierre Boisselier ,&nbsp;Yoann Pointreau ,&nbsp;Lucie Piram ,&nbsp;Juliette Thariat ,&nbsp;Pierre Blanchard","doi":"10.1016/j.canrad.2026.104807","DOIUrl":"10.1016/j.canrad.2026.104807","url":null,"abstract":"<div><div>Radiotherapy in head and neck oncology is advancing thanks to technologies that improve treatment precision, adaptation, and tolerance. The most promising approaches are discussed in this narrative review. The use of automatic segmentation through artificial intelligence (deep learning) now allows rapid delineation of organs at risk, thus reducing contouring time and the risk of errors. Several tools are already routinely used and are evaluated for replanning process. Imaging, acquired before each session, ensures precise patient repositioning. The benefit of using systematic image-guidance to adapt the radiotherapy plan according to anatomical changes remains to be confirmed. The combination of magnetic resonance imaging (MRI) with a linear accelerator ([MRI]-guided linear accelerator), offers a precise and promising option for adaptative radiotherapy at each session. Personalized radiotherapy is being considered for patients with human papillomavirus-related oropharyngeal cancers, which have a better prognosis, through de-escalation strategies aimed at reducing toxicity and preserving quality of life. This includes the possible reduction of prophylactic volumes and doses, as well as dose modulation based on tumor hypoxia detected by functional positron-emission tomography imaging. These approaches are promising but require validation in randomized trials. Intensity-modulated proton therapy improves dose distribution thanks to the Bragg peak, limiting irradiation of healthy tissues. A recent randomized study highlighted better tolerance compared to intensity-modulated proton therapy, without loss of efficacy in oropharyngeal cancer. However, access remains limited in France. Flash radiotherapy, still experimental, delivers ultrarapid doses with reduced toxicity in preclinical studies, pending clinical confirmation. Finally, telemonitoring optimizes the management of side effects and quality of life, with particular interest in clinical trial settings.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"30 1","pages":"Article 104807"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147710024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"External beam radiotherapy for prostatic cancers: 2025 update","authors":"Igor Latorzeff ,&nbsp;Alizée Camps-Maléa ,&nbsp;Christophe Hennequin ,&nbsp;Olivier Chapet ,&nbsp;David Pasquier ,&nbsp;Gilles Créhange ,&nbsp;Pascal Pommiet ,&nbsp;Renaud de Crevoisier ,&nbsp;Pierre Blanchard ,&nbsp;Ulrike Schicke ,&nbsp;Vincent Marchesi ,&nbsp;Paul Sargos ,&nbsp;Stéphane Supiot","doi":"10.1016/j.canrad.2025.104777","DOIUrl":"10.1016/j.canrad.2025.104777","url":null,"abstract":"<div><div>This article reports on the updated recommendations of the Société française de radiothérapie oncologique on external radiotherapy for prostate cancer. External radiotherapy is aimed for all localized prostate cancers, and more recently at oligometastatic prostate cancers. Irradiation techniques are detailed according to different risk levels. Prostate image-guided intensity-modulated radiotherapy is the recommended technique for these cancers. A total dose of 74 to 80<!--> <!-->Gy is recommended for standard fractionation (delivered in 2<!--> <!-->Gy fractions). Moderate hypofractionation (delivering a total dose of 60<!--> <!-->Gy at a rate of 3<!--> <!-->Gy per fraction over 4<!--> <!-->weeks) in the prostate has become a therapeutic standard. Extreme hypofractionation (delivering 35 to 40<!--> <!-->Gy in five fractions) to treat the prostate without pelvis, using a technique under stereotactic conditions, can be considered a recent standard in favourable and intermediate risk disease. The postoperative irradiation technique, mainly indicated in cases of biochemical recurrence and lymph node involvement, is described in detail. Recommendations concerning contouring and dosimetry are also provided.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104777"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiotherapy for primary lung cancer: 2025 update","authors":"Jonathan Khalifa ,&nbsp;Yasmine El Houat ,&nbsp;Sébastien Thureau ,&nbsp;Julien Darréon ,&nbsp;Delphine Antoni ,&nbsp;Eivind Blais ,&nbsp;Cécile Le Péchoux ,&nbsp;Delphine Lerouge ,&nbsp;Antonin Levy ,&nbsp;François Lucia ,&nbsp;Alexis Marguerit ,&nbsp;Étienne Martin ,&nbsp;Baptiste Pichon ,&nbsp;Nicolas Pourel ,&nbsp;Philippe Giraud ,&nbsp;François-Georges Riet","doi":"10.1016/j.canrad.2025.104779","DOIUrl":"10.1016/j.canrad.2025.104779","url":null,"abstract":"<div><div>Herein are presented the update of the recommendations from the Société française de radiothérapie oncologique (the French society for radiation oncology) regarding the indications and methods of lung cancer radiotherapy. The recommendations for delineation of the target volumes and organs at risk are detailed.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104779"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RadioTransNet: Preclinical research network coordinated by the Société française de radiothérapie oncologique and Société française de physique médicale, 2025 update","authors":"Émilie Bayart ,&nbsp;Marc Benderitter ,&nbsp;François Boussin ,&nbsp;Jacques Balosso ,&nbsp;Éric Deutsch ,&nbsp;Élizabeth Cohen Jonathan-Moyal ,&nbsp;Thomas Lacornerie ,&nbsp;Sophie Pinel ,&nbsp;Yolanda Prezado ,&nbsp;Charlotte Robert ,&nbsp;Stéphane Supiot ,&nbsp;Grégory Delpon ,&nbsp;Céline Bourgier","doi":"10.1016/j.canrad.2025.104764","DOIUrl":"10.1016/j.canrad.2025.104764","url":null,"abstract":"<div><div>The RadioTransNet program, led by the Société française de radiothérapie oncologique (SFRO, the French society for radiation oncology) in association with the Société française de physique médicale (SFPM, the French society of medical physics), certified by the Institut du cancer (INCa, the French national cancer institute), was created at the end of 2018. The aim is to create a coherent, national, and multidisciplinary structure for preclinical and translational research in oncological radiotherapy by identifying research priorities. Its activities are coordinated by a scientific council, composed of radiation oncologists-therapists, medical physicists and academic radiobiologists researchers, and organized around four major axes which are: the definition of target volumes, the interaction of ionizing radiation with tissues, combined treatments and modern approaches to dose calculation. These four major axes are associated with different objectives concerning basic radiobiology, the studies of implementation of new drugs in preclinical settings, the contribution of imaging and new tracers, research in medical physics, by integrating a cross-cutting dimension of medical oncology and cost/effectiveness considerations. The selected themes form the basis for the projects studied and developed, taking into account the complementary skills of all the partner platforms involved in the network. Orientation proposals based on the priorities selected by the scientific council are submitted to INCa for the opening of dedicated calls to finance the human and technical resources necessary to conduct, under the best conditions, preclinical and translational research in radiotherapy.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104764"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145607890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiotherapy for oral cavity cancers: 2025 update","authors":"Yasmine El Houat ,&nbsp;Michel Lapeyre ,&nbsp;Sophie Renard ,&nbsp;Séverine Racadot ,&nbsp;Laure Vieillevigne ,&nbsp;Anouchka Modesto ,&nbsp;Pierre Blanchard ,&nbsp;Yoann Pointreau","doi":"10.1016/j.canrad.2025.104771","DOIUrl":"10.1016/j.canrad.2025.104771","url":null,"abstract":"<div><div>Intensity-modulated conformal radiotherapy and brachytherapy are among the standard techniques for radiation treatments of oral cavity cancers. In this paper, each technique is detailed in terms of indications, treatment planning, volume delineation and selection, dosimetry, and position verification. This document represents an update of the Société française de radiothérapie oncologique (the French society for radiation oncology) guidelines (RecoRad™) for this anatomical site within the upper aerodigestive tract.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104771"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiotherapy for penile cancers: 2025 update","authors":"Geneviève Loos ,&nbsp;Alexandre Escande ,&nbsp;Sabrina Aziez ,&nbsp;Vincent Marchesi ,&nbsp;Paul Sargos ,&nbsp;Mario Terzilli ,&nbsp;Igor Latorzeff ,&nbsp;Stéphane Supiot ,&nbsp;Vérane Achard ,&nbsp;Jennifer Le Guévelou ,&nbsp;Aude Flechon ,&nbsp;Jean-Michel Hannoun-Lévi ,&nbsp;Cyrus Chargari","doi":"10.1016/j.canrad.2025.104761","DOIUrl":"10.1016/j.canrad.2025.104761","url":null,"abstract":"<div><div>This article presents an update of the French national guidelines for the management of penile cancer, with recommendations on dose and volume for radiotherapy and brachytherapy. Multidisciplinary management and centralization in high-level of expertise centres is key for the management of this rare malignancy. For patients at high-risk of having micrometastatic disease (stage T1b or higher), a dynamic sentinel node biopsy should be offered as surgical staging and human papillomavirus status should be obtained. Organ-preservation with brachytherapy should be discussed whenever it is possible (tumours limited to the glans). For locoregionally advanced diseases, chemoradiotherapy as primary treatment could be discussed.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104761"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145462448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of radiotherapy in the management of primary renal cell carcinoma: Recommendations from the Société française de radiothérapie oncologique (SFRO, the French society for radiation oncology)","authors":"Nicolas Benziane-Ouaritini ,&nbsp;Jennifer Le Guevelou ,&nbsp;Stéphane Supiot ,&nbsp;Mario Terlizzi ,&nbsp;Olivier Chapet ,&nbsp;Idir Ouzaid ,&nbsp;David Pasquier ,&nbsp;Vincent Marchesi ,&nbsp;Igor Latorzeff ,&nbsp;Paul Sargos","doi":"10.1016/j.canrad.2025.104713","DOIUrl":"10.1016/j.canrad.2025.104713","url":null,"abstract":"<div><div>Renal cell carcinoma represents the 14th most frequent tumour worldwide, but its incidence is increasing partly due to incidental diagnoses. As a result, these tumours are diagnosed in patients at an increasingly advanced age, often frail and with comorbidities. Most renal cell carcinoma cases are clear cell carcinoma (80 %), with papillary tumours being the second most frequent histological subtype. The standard of care for localized RCC is surgery, with partial nephrectomy or radical nephrectomy being recommended for T1 and T2 tumours, respectively. Thermoablative strategies have been developed over the past decade for patients who are not amenable to surgery and/or with impaired renal function. Active surveillance remains an alternative in the case of small low-grade renal cell carcinoma. Recent research has evaluated stereotactic ablative body radiotherapy as a well-tolerated and effective treatment for small renal tumours essentially for the management of both T1a and T1b tumours. This article aims to report the recommendations of the Société française de radiothérapie oncologique (SFRO, the French society for radiation oncology) on the role of radiotherapy in the management of localized renal cell carcinoma. These guidelines describe both treatment planning modalities, target volumes, and follow-up procedures. They also focus on the impact of radiotherapy on renal function, and the specific dosimetric constraints to be implemented.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104713"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiotherapy of bone metastases: 2025 update","authors":"Nicolas Martz ,&nbsp;Jean Christophe Faivre ,&nbsp;Guillaume Beldjoudi ,&nbsp;Antoine Arnaud ,&nbsp;Jérôme Chamois ,&nbsp;Stéphane Supiot ,&nbsp;Maximilien Rogé ,&nbsp;Sébastien Thureau","doi":"10.1016/j.canrad.2025.104769","DOIUrl":"10.1016/j.canrad.2025.104769","url":null,"abstract":"<div><div>We present the updated recommendations of the Société française de radiothérapie oncologique (the French society for radiation oncology) regarding the indications and technical modalities of radiotherapy for bone metastases. This treatment is commonly used in the management of patients with cancer. In most cases, it involves relatively simple radiotherapy technique with proven efficacy in reducing pain or managing spinal cord compression. More complex treatments using stereotactic conditions can be proposed for patients with painful bone metastases, oligometastatic disease, or in case of reirradiation. In this context, increased vigilance must be given to the risks of spinal cord toxicity.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104769"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of radiotherapy in the treatment of primary vaginal cancer: Recommendations of the Société française de radiothérapie oncologique, 2025 update","authors":"Cyrus Chargari ,&nbsp;Anne Ducassou ,&nbsp;Camille Roukoz ,&nbsp;François Lucia ,&nbsp;Adeline Petit ,&nbsp;Abel Cordoba ,&nbsp;Caroline Lafond ,&nbsp;Sophie Renard ,&nbsp;Alexandre Escande","doi":"10.1016/j.canrad.2025.104725","DOIUrl":"10.1016/j.canrad.2025.104725","url":null,"abstract":"<div><div>Primary vaginal cancers are rare tumours, for which external beam radiotherapy and brachytherapy are major treatment tools. Given the complexity of brachytherapy techniques, the treatment should be performed in specialised centres. We present the 2025 update of recommendations of the Société française de radiothérapie oncologique on the indications and techniques for external beam radiotherapy and brachytherapy for primary vaginal cancer.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104725"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}