Cancer Epidemiology, Biomarkers & Prevention最新文献

{"title":"Selected Articles from This Issue","authors":"","doi":"10.1158/1055-9965.epi-32-11-hi","DOIUrl":"https://doi.org/10.1158/1055-9965.epi-32-11-hi","url":null,"abstract":"Highlights| November 01 2023 Selected Articles from This Issue Author & Article Information Online ISSN: 1538-7755 Print ISSN: 1055-9965 ©2023 American Association for Cancer Research2023American Association for Cancer Research Cancer Epidemiol Biomarkers Prev (2023) 32 (11): 1475. https://doi.org/10.1158/1055-9965.EPI-32-11-HI Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Article Versions Icon Versions Version of Record November 1 2023 Citation Selected Articles from This Issue. Cancer Epidemiol Biomarkers Prev 1 November 2023; 32 (11): 1475. https://doi.org/10.1158/1055-9965.EPI-32-11-HI Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search Advanced Search This study by Forjaz and colleagues is the first comprehensive analysis of long-term incidence and survival trends for several cancer sites by stage. The authors created a new variable, Long-Term Site-Specific Summary Stage, and applied it to 25 cancer sites to allow analyses of long-term cancer incidence and survival trends by stage from as early as 1975. They report remarkable improvements in cancer survival since 1975, namely for cancers that have traditionally had a poor prognosis and no organized screening programs, which likely reflect advances in managing and treating these cancers. This study will be particularly useful for understanding the population-level impact of new treatments and identifying emerging trends in health disparities research. Risk prediction models may improve effective and efficient use of supplemental surveillance imaging for individuals with a personal history of breast cancer. However, using risk models to guide supplemental imaging recommendations may contribute to disparities. Using simulation... You do not currently have access to this content.","PeriodicalId":9488,"journal":{"name":"Cancer Epidemiology, Biomarkers & Prevention","volume":"285 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135273643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selected Articles from This Issue","authors":"","doi":"10.1158/1055-9965.epi-32-10-hi","DOIUrl":"https://doi.org/10.1158/1055-9965.epi-32-10-hi","url":null,"abstract":"Highlights| October 02 2023 Selected Articles from This Issue Author & Article Information Online ISSN: 1538-7755 Print ISSN: 1055-9965 ©2023 American Association for Cancer Research2023American Association for Cancer Research Cancer Epidemiol Biomarkers Prev (2023) 32 (10): 1273. https://doi.org/10.1158/1055-9965.EPI-32-10-HI Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Article Versions Icon Versions Version of Record October 2 2023 Citation Selected Articles from This Issue. Cancer Epidemiol Biomarkers Prev 1 October 2023; 32 (10): 1273. https://doi.org/10.1158/1055-9965.EPI-32-10-HI Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search Advanced Search Although esophageal cancer mortality is high in China, evidence suggests that mortality varies considerably by region. Using nationwide survey and cancer registry data from 782 counties in China, Ran and colleagues examined how geographic disparities in esophageal cancer mortality changed over time and investigated possible associations with socioeconomic status. Between 1973–1975 and 2015–2017, 577 (74%) counties experienced decreasing esophageal cancer mortality. Intercounty differences in mortality substantially narrowed, but geographic clusters of elevated rates persisted. Notably, elevated mortality rates were observed in counties with low socioeconomic status. These findings highlight the importance of continued efforts to address geographic and socioeconomic inequalities. Inequalities in high-quality breast cancer treatment are well established, however, the diagnostic procedures and clinical workups necessary to determine the optimal course of cancer-directed treatment are rarely considered. Herbach and colleagues provide a detailed depiction of disparities along the breast cancer continuum of care using SEER-Medicare data to examine racial–ethnic... You do not currently have access to this content.","PeriodicalId":9488,"journal":{"name":"Cancer Epidemiology, Biomarkers & Prevention","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135835434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selected Articles from This Issue","authors":"","doi":"10.1158/1055-9965.epi-32-9-hi","DOIUrl":"https://doi.org/10.1158/1055-9965.epi-32-9-hi","url":null,"abstract":"Highlights| September 01 2023 Selected Articles from This Issue Author & Article Information Online ISSN: 1538-7755 Print ISSN: 1055-9965 ©2023 American Association for Cancer Research2023American Association for Cancer Research Cancer Epidemiol Biomarkers Prev (2023) 32 (9): 1125. https://doi.org/10.1158/1055-9965.EPI-32-9-HI Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Article Versions Icon Versions Version of Record September 1 2023 Citation Selected Articles from This Issue. Cancer Epidemiol Biomarkers Prev 1 September 2023; 32 (9): 1125. https://doi.org/10.1158/1055-9965.EPI-32-9-HI Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search Advanced Search The risk for colorectal cancer and colon polyps, the precursors to colorectal cancer, varies between people for largely unclear reasons, one of which is field cancerization. The evidence for field cancerization in the colon has been modest to date. In this study, Yu and colleagues carried out studies using methylated EVL as a marker for field cancerization in the colon and a possible risk biomarker for colon polyps. The authors found mEVL associated with a 3X increased risk for colon polyps. Results provide more support for colon field cancerization and suggest mEVL may be a novel risk marker for colorectal cancer and therapeutic target for colorectal cancer chemoprevention. Human papillomavirus (HPV) cell entry through host cell surface receptors could correlate with infectivity and may play a role in cervical precancer progression. It has been shown that heparan sulfate proteoglycans (HSPG), specifically the syndecan and glypican gene families are... You do not currently have access to this content.","PeriodicalId":9488,"journal":{"name":"Cancer Epidemiology, Biomarkers & Prevention","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135048897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selected Articles from This Issue","authors":"","doi":"10.1158/1055-9965.epi-32-8-hi","DOIUrl":"https://doi.org/10.1158/1055-9965.epi-32-8-hi","url":null,"abstract":"Highlights| August 01 2023 Selected Articles from This Issue Author & Article Information Online ISSN: 1538-7755 Print ISSN: 1055-9965 ©2023 American Association for Cancer Research2023American Association for Cancer Research Cancer Epidemiol Biomarkers Prev (2023) 32 (8): 995. https://doi.org/10.1158/1055-9965.EPI-32-8-HI Related Content This is a commentary to: Prediagnostic 25-Hydroxyvitamin D in Association with Cancer-specific and All-cause Mortality among Low-income, Non-Hispanic Black Americans with Colorectal Cancer This is a commentary to: Incidence and Mortality Rates for Childhood Acute Lymphoblastic Leukemia in Puerto Rican Hispanics, 2012–2016 This is a commentary to: Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium View more This is a commentary to: Field Synopsis of Environmental and Genetic Risk Factors of Sporadic Early-Onset Colorectal Cancer and Advanced Adenoma View less Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Article Versions Icon Versions Version of Record August 1 2023 Citation Selected Articles from This Issue. Cancer Epidemiol Biomarkers Prev 1 August 2023; 32 (8): 995. https://doi.org/10.1158/1055-9965.EPI-32-8-HI Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search Advanced Search Acute lymphoblastic leukemia (ALL) accounts for 80% of all leukemias diagnosed in children. Although ALL age patterns are consistent across racial/ethnic groups, their incidence and mortality rates are highly variable. Montes-Rodríguez and colleagues assessed the age-standardized ALL incidence and mortality rates of Puerto Rican Hispanic (PRH) children and compared them with those of US mainland Hispanics, non-Hispanic whites, non-Hispanic blacks and Non-Hispanic Asian or Pacific Islanders. PRH children were found to have disparities in ALL incidence and mortality rates compared to other racial/ethnic groups in the US. Additional research is warranted to identify the genetic and environmental risk factors that may be associated with the disparities observed. This study by Zhang and colleagues synthesized available epidemiological evidence on the associations of environmental and genetic factors with the risk of sporadic early-onset colorectal cancer (EOCRC) and early-onset advanced colorectal adenoma (EOCRA). A total of 61 studies were included, reporting 120 environmental... You do not currently have access to this content.","PeriodicalId":9488,"journal":{"name":"Cancer Epidemiology, Biomarkers & Prevention","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135970598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstract 40: Global Cancer Surgery in Low-Resource Settings: A Strengths, Weaknesses, Opportunities, and Threats Analysis","authors":"Samantha Sadler, Erick Torio, Alexandra Golby","doi":"10.1158/1538-7755.asgcr23-abstract-40","DOIUrl":"https://doi.org/10.1158/1538-7755.asgcr23-abstract-40","url":null,"abstract":"Abstract Background: Cancer surgery is a resource-intensive yet essential component of cancer care. In the face of projected increase in cancer burden, the present gap in cancer surgery care in low-resource settings with stressed healthcare and surgical infrastructure risks further exacerbation. Understanding the current state of global cancer surgery is essential to determining the best way forward. Purpose: The objectives of this report are to (1) describe the landscape of global cancer surgery literature and (2) characterize these findings through a Strengths, Weaknesses, Opportunities, and Threats (SWOT) analysis. Methods: A literature review was performed of global cancer surgery studies involving low-resource settings published since the landmark 2015 Lancet Commission on Global Surgery and Global Cancer Surgery. Studies were summarized and evaluated for themes, which were further grouped into SWOT categories for analysis. Results: The online literature search yielded 123 articles, of which 46 articles met inclusion criteria for analysis. The majority of included studies were open access (n=34) and published between 2021 and 2022 (n=26). Conclusion: The body of published global cancer surgery literature is growing, perhaps reflecting increased research attention and valuation. From the reviewed literature, Strengths of the global cancer surgery field include a body of studies investigating important aspects of cancer surgery in low-resource settings: local cancer epidemiology, local surgical and technological innovation, quality-of-life as a key surgical outcome metric, and advancements in cancer surgery through interdisciplinary work. Weaknesses include systems-level limitations (i.e. resources, perioperative services, broader health system gaps) and a paucity of detailed economic analyses. Opportunities include diverse local cancer management strategies, successful inter-setting collaborations supporting research, education, and surgical skills training, and thoughtful research expansion for an inclusive future. Threats include large-scale stresses on local healthcare infrastructure (i.e. COVID-19) and the risk of widening disparities posed by unchecked technological. Conclusion: This SWOT analysis may inform local intervention strategies and action plans to help LMIC stakeholders achieve cancer surgery goals. Similar analyses are needed locally to help elucidate best practices that might be applied or tailored to similar settings globally. Citation Format: Samantha Sadler, Erick Torio, Alexandra Golby. Global Cancer Surgery in Low-Resource Settings: A Strengths, Weaknesses, Opportunities, and Threats Analysis [abstract]. In: Proceedings of the 11th Annual Symposium on Global Cancer Research; Closing the Research-to-Implementation Gap; 2023 Apr 4-6. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(6_Suppl):Abstract nr 40.","PeriodicalId":9488,"journal":{"name":"Cancer Epidemiology, Biomarkers & Prevention","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135727421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selected Articles from This Issue","authors":"","doi":"10.1158/1055-9965.epi-32-6-hi","DOIUrl":"https://doi.org/10.1158/1055-9965.epi-32-6-hi","url":null,"abstract":"Highlights| June 01 2023 Selected Articles from This Issue Author & Article Information Online ISSN: 1538-7755 Print ISSN: 1055-9965 ©2023 American Association for Cancer Research2023American Association for Cancer Research Cancer Epidemiol Biomarkers Prev (2023) 32 (6): 739. https://doi.org/10.1158/1055-9965.EPI-32-6-HI Related Content A commentary has been published: Trend in Cervical Cancer Incidence and Mortality Rates in China, 2006–2030: A Bayesian Age-Period-Cohort Modeling Study A commentary has been published: Efficacy of the Outsmart HPV Intervention: A Randomized Controlled Trial to Increase HPV Vaccination among Young Gay, Bisexual, and Other Men Who Have Sex with Men A commentary has been published: Survival of Middle Eastern and North African Individuals Diagnosed with Colorectal Cancer: A Population-Based Study in California View more A commentary has been published: Somatic Mosaic Chromosomal Alterations and Death of Cardiovascular Disease Causes among Cancer Survivors View less Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Article Versions Icon Versions Version of Record June 1 2023 Citation Selected Articles from This Issue. Cancer Epidemiol Biomarkers Prev 1 June 2023; 32 (6): 739. https://doi.org/10.1158/1055-9965.EPI-32-6-HI Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search Advanced Search Routine human papillomavirus (HPV) vaccination is recommended for young adults, yet many young gay, bisexual, and other men who have sex with men (YGBMSM) remain unvaccinated. Reiter and colleagues report the efficacy of Outsmart HPV, a web-based HPV vaccination intervention for YGBMSM. Results showed that Outsmart HPV increased HPV vaccination among participants and that participants reported higher levels of satisfaction with the intervention. These data suggest that Outsmart HPV is an efficacious intervention and a promising tool for increasing HPV vaccination among YGBMSM. Cardiovascular disease is a major cause of illness and death in cancer patients. Sun and colleagues analyzed data from the UK Biobank to investigate the link between mosaic chromosomal alterations (mCAs), a type of clonal hematopoiesis, and cardiovascular outcomes in cancer patients. The authors found that patients with mCAs had a significantly higher risk of death from coronary artery disease compared to those without mCAs. These findings... You do not currently have access to this content.","PeriodicalId":9488,"journal":{"name":"Cancer Epidemiology, Biomarkers & Prevention","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135727240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstract 58: Leaving Cancer Patients Behind for Greener Pastures: The Clinical Oncology Workforce in Nigeria","authors":"Runcie C.W. Chidebe, Tochukwu C. Orjikor, Onyinye Balogun, Adedayo Joseph, Samantha Toland, Alison Simons","doi":"10.1158/1538-7755.asgcr23-abstract-58","DOIUrl":"https://doi.org/10.1158/1538-7755.asgcr23-abstract-58","url":null,"abstract":"Abstract Purpose: For a population of over 201 million, Nigeria has only 4 doctors per 10,000 patients and 16.1 nurses, midwives per 10,000 patients, and less than 100 clinical oncologists for over 100,000 cancer patients. While Nigeria has one of the worst disease burdens in the world and a workforce shortage; 9 in 10 Nigerian physicians are seeking opportunities to leave for the USA, UK, and Canada. To improve oncology care in Nigeria, it may be important to understand the push and pull factors contributing to the migration of the clinical oncology (CO) workforce. Mathew (2018), Vanderpuye, et al., (2019), Balogun, et al., (2017), and Adebayo, (2016) have done research on CO; however, their studies were vastly focused on the African continent and not country-specific nor focused on the CO workforce in Nigeria.The aim of this study is to explore the push and pull factors to stay or leave the clinical oncology workforce in Nigeria. Methods: Using a mixed-method research approach, 80 participants completed the questionnaire and 9 participants responded to semi-structured interviews. Multiple linear regression and Grounded theory were used for the data analysis. Results: The results show that CO workload and satisfaction were significantly related to turnover intention. The qualitative results showed that CO as a new area of specialization, mentorship, career growth, and attractiveness of radiation science are the pull factors. While, high CO workload, poor healthcare system, poor remuneration, corruption in the public sector, and a few other themes are push factors. Empathy for patients, patriotism and a sense of fulfillment unexpectedly emerged as retention factors in the study. Conclusion: Nigeria can improve patient treatment outcomes by the reduction of CO workload through the employment of more CO. More CO can be available for employment when they are attracted, and their training is optimized. Those employed can be retained by improving working conditions and introducing work benefits. Our recommendations are that health leaders should create more CO training and awareness of CO in Nigeria. Citation Format: Runcie C.W. Chidebe, Tochukwu C. Orjikor, Onyinye Balogun, Adedayo Joseph, Samantha Toland, Alison Simons. Leaving Cancer Patients Behind for Greener Pastures: The Clinical Oncology Workforce in Nigeria [abstract]. In: Proceedings of the 11th Annual Symposium on Global Cancer Research; Closing the Research-to-Implementation Gap; 2023 Apr 4-6. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(6_Suppl):Abstract nr 58.","PeriodicalId":9488,"journal":{"name":"Cancer Epidemiology, Biomarkers & Prevention","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135728373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstract 36: Examining Policies and Guidelines to Improve the Cervical Cancer Prevention and Treatment Pathway for Patients and Health Providers in Tanzania: A Qualitative Study","authors":"Melinda Chelva, Sanchit Kaushal, Nicola West, Erica Erwin, Prisca Dominic Marandu, Safina Yuma, Donna Shelley, Karen Yeates","doi":"10.1158/1538-7755.asgcr23-abstract-36","DOIUrl":"https://doi.org/10.1158/1538-7755.asgcr23-abstract-36","url":null,"abstract":"Abstract Purpose: Cervical cancer is the fourth most common cancer in women around the globe. It has been identified as the most common cancer in Tanzania, resulting in about 9772 new cases and 6695 deaths each year. Several research studies have identified the importance of adequate and timely policies and guidelines to optimize the cervical cancer prevention and treatment pathway in the nation. However, there is scant literature on the perspectives of all stakeholders (e.g., patients, key informants, healthcare providers, and non-healthcare providers). Our study aims to better understand the recommendations from important stakeholders to inform current and upcoming policies and guidelines, and overall, improve the cervical cancer screening and treatment cascade in rural Tanzania and other African countries. Methods: We leveraged a framework for conducting a health systems assessment to identify healthcare providers’ perspectives on effective cervical cancer screening, prevention and control in Tanzania. We adapted interview topic guides for cervical cancer screening using the health systems assessment framework conceptualized by Risso-Gill and colleagues designed initially for evaluating hypertension control. Study participants (71) were interviewed between 2014-2018. This included key stakeholders, patients, healthcare providers and non-healthcare providers. Results: Through the interviews and focus group discussions that were conducted, three major themes emerged: 1) policies and guidelines, 2) burden of disease in relation to policies, and 3) treatment and follow-up. Sub-themes relating to policies and guidelines included health policies, governmental influence, data collection, and revision of HPV vaccination guidelines. Sub-themes for burden of disease included the rise in overall cases of cervical cancer. Subthemes for treatment and follow-up included quality of care, dissatisfaction with care, and patient safety and well-being. Conclusion: It is evident that significant changes must be made to existing policies and guidelines to improve many aspects of the cervical cancer screening and treatment pathway, to benefit healthcare providers and patients alike in rural Tanzania. There is also a critical need to implement new initiatives and programs to increase uptake and allow for informed-decision making among women. Citation Format: Melinda Chelva, Sanchit Kaushal, Nicola West, Erica Erwin, Prisca Dominic Marandu, Safina Yuma, Donna Shelley, Karen Yeates. Examining Policies and Guidelines to Improve the Cervical Cancer Prevention and Treatment Pathway for Patients and Health Providers in Tanzania: A Qualitative Study [abstract]. In: Proceedings of the 11th Annual Symposium on Global Cancer Research; Closing the Research-to-Implementation Gap; 2023 Apr 4-6. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(6_Suppl):Abstract nr 36.","PeriodicalId":9488,"journal":{"name":"Cancer Epidemiology, Biomarkers & Prevention","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135728171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstract 39: Factors Associated With Receiving Results and Attending Colposcopy in Patients With Positive HPV Screens in Mexico City","authors":"Leith León-Maldonado, Raul U. Hernández-Ramírez, Leticia Torres-Ibarra, Donna Spiegelman, Sangini S Sheth, Eduardo Lazcano-Ponce, José Damián Cadena-Fiscal, Jorge Salmerón","doi":"10.1158/1538-7755.asgcr23-abstract-39","DOIUrl":"https://doi.org/10.1158/1538-7755.asgcr23-abstract-39","url":null,"abstract":"Abstract Purpose: Unlike in high-income countries, where cervical cancer (CC) screening programs have resulted in a dramatic decrease in incidence and mortality of this nearly fully preventable disease, in low- and middle-income countries, the impact of these programs has been limited. Poor follow-up to abnormal cancer screening tests lessens the benefit of CC screening. We sought to identify multilevel factors at the level of patient, provider, and healthcare system related to receipt of screening results and attendance to colposcopy among patients with positive screening results in a CC screening program in Mexico. Methods: We studied 1,351 patients who were scheduled for colposcopy after testing positive for high-risk human papillomavirus in two screening demonstration studies conducted in Mexico City’s Tlalpan District (2017-2018). Multilevel factors associated with receipt of screening results and with adherence to a colposcopy appointment were identified using multivariable logistic regression. Results: Participants had a median age of 40 years, 58% had less than high school education, and 74% had a Pap screening recently (i.e., in the last 5 years). Fifty-five percent of participants retrieved their screening results at the healthcare facility before being reminded to do so. Greater adherence to obtaining screening test results was associated with providing an email address as contact information (Odds Ratio 1.35 [95% Confidence Interval 1.03-1.77]), attending a facility with family medicine (1.54 [1.07-2.21]), and receiving care from experienced nurses (1.85 [1.30-2.70]). Fifty-seven percent of participants attended their first scheduled colposcopy appointment. Providing a phone number as contact information was linked to improved adherence to colposcopy (1.27 [1.01-1.59]), whereas longer travel time between the healthcare facility and the colposcopy clinic was associated with a decrease in colposcopy adherence (0.68 [0.49-0.94]). Having a Pap recently was positively associated with better compliance with both outcomes (1.36 [0.96-1.94] for receiving results; 1.59 [1.10-2.29] for colposcopy adherence). Conclusion: We identified multilevel factors associated with abnormal test follow-up in patients in Mexico City. Additional research is necessary to design and test components for a multilevel intervention to address these factors and enable successful implementation of the follow-up process for abnormal screens from screening to diagnosis and treatment. Citation Format: Leith León-Maldonado, Raul U. Hernández-Ramírez, Leticia Torres-Ibarra, Donna Spiegelman, Sangini S Sheth, Eduardo Lazcano-Ponce, José Damián Cadena-Fiscal, Jorge Salmerón. Factors Associated With Receiving Results and Attending Colposcopy in Patients With Positive HPV Screens in Mexico City [abstract]. In: Proceedings of the 11th Annual Symposium on Global Cancer Research; Closing the Research-to-Implementation Gap; 2023 Apr 4-6. Philadelphia (PA): AACR; Cancer Epidemiol B","PeriodicalId":9488,"journal":{"name":"Cancer Epidemiology, Biomarkers & Prevention","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135727417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selected Articles from This Issue","authors":"","doi":"10.1158/1055-9965.epi-32-5-hi","DOIUrl":"https://doi.org/10.1158/1055-9965.epi-32-5-hi","url":null,"abstract":"Highlights| May 01 2023 Selected Articles from This Issue Author & Article Information Online ISSN: 1538-7755 Print ISSN: 1055-9965 ©2023 American Association for Cancer Research2023American Association for Cancer Research Cancer Epidemiol Biomarkers Prev (2023) 32 (5): 583. https://doi.org/10.1158/1055-9965.EPI-32-5-HI Related Content A commentary has been published: Changes in Breast Cancer Risk and Risk Factor Profiles among U.S.-Born and Immigrant Asian American Women Residing in the San Francisco Bay Area A commentary has been published: Risk and Protective Factors for Cancer Mortality among United States Service Members and Veterans (2001–2018) A commentary has been published: Risk Factors and Trends for HPV-Associated Subsequent Malignant Neoplasms among Adolescent and Young Adult Cancer Survivors View more A commentary has been published: Rural, Large Town, and Urban Differences in Optimal Subspecialty Follow-up and Survivorship Care Plan Documentation among Childhood Cancer Survivors View less Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Article Versions Icon Versions Version of Record May 1 2023 Citation Selected Articles from This Issue. Cancer Epidemiol Biomarkers Prev 1 May 2023; 32 (5): 583. https://doi.org/10.1158/1055-9965.EPI-32-5-HI Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search Advanced Search This longitudinal study analyzed data from the Millennium Cohort Study (2001–2018) to examine risk and protective factors for cancer mortality among service members and veterans. Findings revealed that non-deployers were more likely to die from cancer compared with deployers who did not experience combat, consistent with the healthy deployer effect. The study by Sharifian and colleagues also found that enlisted personnel were more likely to die from lung cancer than officers. This research is timely given current mandates to examine whether military-related exposures affect cancer risk among service members and veterans, including President Biden's Cancer Moonshot Program and the newly enacted VA PACT Act. Using Surveillance, Epidemiology, and End Results (SEER) program data from 1976 to 2015, Ou and colleagues used multiple methods to address unexamined questions about risk factors for Human-papillomavirus (HPV) associated second malignant neoplasms (SMN) among adolescent and young adult (AYA). The authors found that the burden... You do not currently have access to this content.","PeriodicalId":9488,"journal":{"name":"Cancer Epidemiology, Biomarkers & Prevention","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136095624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}