Ayman A. Mohamed PhD , Yih-Kuen Jan PhD , Neveen Abdel Raoof PhD , Omaima Kattabei PhD , Ibrahim Moustafa PhD , Hanan Hosny MD
{"title":"Effect of Biofeedback Corrective Exercise on Reaction Time and Central Somatosensory Conduction Time in Patients With Forward Head Posture and Radiculopathy: A Randomized Controlled Study","authors":"Ayman A. Mohamed PhD , Yih-Kuen Jan PhD , Neveen Abdel Raoof PhD , Omaima Kattabei PhD , Ibrahim Moustafa PhD , Hanan Hosny MD","doi":"10.1016/j.jcm.2022.01.001","DOIUrl":"10.1016/j.jcm.2022.01.001","url":null,"abstract":"<div><h3>Objective</h3><p><span>The purpose of this study was to examine the effect of 8 weeks of biofeedback on reaction time and central somatosensory conduction time </span>in patients<span><span> with forward head posture and </span>cervical radiculopathy.</span></p></div><div><h3>Methods</h3><p><span>We performed a double-blinded randomized controlled trial<span>. Seventy patients with forward head posture and cervical radiculopathy were randomly distributed into study and control groups. The study group received biofeedback forward head posture corrective exercise for 8 weeks, while the control group did not receive any treatment. The main outcome measures were reaction time and central somatosensory conduction time. The secondary outcome measures were the craniovertebral angles, </span></span>nerve conduction time<span> at N13<span> and N20, referred arm pain, and neck disability index.</span></span></p></div><div><h3>Results</h3><p>After 4 weeks, there were nonsignificant differences between both groups in reaction time and central somatosensory conduction time (<em>P</em> > .05); while there were significant differences between both groups in N13, N20, craniovertebral angle, referred arm pain, and neck disability index scores (<em>P</em> < .05). After 8 weeks, there were significant differences between both groups in all outcome measures (<em>P</em> < .05).</p></div><div><h3>Conclusion</h3><p>In this study, participants receiving biofeedback forward head posture corrective exercise improved both reaction time and central somatosensory conduction time after 8 weeks when compared to a control, nontreatment group.</p></div>","PeriodicalId":94328,"journal":{"name":"Journal of chiropractic medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40393949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Dry Needling and Inhibitory Kinesio Taping in Treatment of Myofascial Pain Syndrome of the Upper Trapezius Muscle: A Randomized Controlled Trial","authors":"Rasool Bagheri PT, PhD , Cyrus Taghizadeh Delkhoush PT, PhD , Majid Mirmohammadkhani MD, PhD , Ziaeddin Safavi Farokhi PT, PhD , Soghra Bakhshi PT, MSc","doi":"10.1016/j.jcm.2022.01.003","DOIUrl":"10.1016/j.jcm.2022.01.003","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this study was to compare the effects of dry needling<span><span><span> and inhibitory Kinesio taping on the pressure pain threshold<span> and muscle thickness in women with </span></span>myofascial pain syndrome in the upper </span>trapezius muscle.</span></p></div><div><h3>Methods</h3><p><span>The present study was a single-blind randomized controlled clinical trial<span>. Seventy-five women with active trigger points in the upper trapezius muscle were included and randomly divided into 3 groups of equal sizes. Groups 1 and 2 were treated in 2 sessions with a 3-day interval by dry needling and inhibitory Kinesio taping, respectively. Group 3 did not receive treatment (ie, the control group). Pressure pain threshold and muscle thickness were measured using a pressure </span></span>algometer and an ultrasound device, respectively, and this was done before, 3 days after, and 10 days after the treatment.</p></div><div><h3>Results</h3><p>Pressure pain threshold increased significantly in groups 1 and 2 (<em>P</em> < .001) after the intervention. Muscle thickness reduced significantly in group 1 (<em>P</em> = .015) and group 2 (<em>P</em> = .010) after the intervention. No significant differences were observed between these 2 intervention groups in terms of these variables. Meanwhile, the changes in the control group in muscle thickness (<em>P</em> = .430) and pressure pain threshold (<em>P</em> = .230) were not significant.</p></div><div><h3>Conclusion</h3><p>Both dry needling and inhibitory Kinesio taping increased pressure pain threshold and reduced muscle thickness in participants with active trigger points in the upper trapezius muscle. These 2 therapeutic techniques appear to cause similar positive changes in pain and muscle function but may do so through different mechanisms.</p></div>","PeriodicalId":94328,"journal":{"name":"Journal of chiropractic medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40393947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason P. Moses PT, OCS, COMT, FAAOMPT , Steve Karas DSc, PT, OCS, CMPT, MA
{"title":"Evaluation and Treatment of Trigeminal Symptoms of Cervical Origin After a Motor-Vehicle Crash: A Case Report With 9-Month Follow-up","authors":"Jason P. Moses PT, OCS, COMT, FAAOMPT , Steve Karas DSc, PT, OCS, CMPT, MA","doi":"10.1016/j.jcm.2022.01.007","DOIUrl":"10.1016/j.jcm.2022.01.007","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this case report is to describe the management of a patient with trigeminal symptoms of cervical origin after a motor-vehicle crash (MVC).</p></div><div><h3>Clinical Features</h3><p>After a head-on MVC, a 65-year-old woman presented with complaints of dizziness<span>, headaches, facial tingling, visual disturbance, tinnitus, loss of cervical motion, and pain in the cervical spine.</span></p></div><div><h3>Intervention and Outcome</h3><p>The intervention applied was manipulation of the left C1-C2 and right C2-C3, with targeted exercise to strengthen the cervical musculature. After 4 weeks of treatment, the patient reported improvement in functional tasks and reduction in overall pain, headaches, facial tingling, tinnitus, and dizziness. At a 9-month follow-up, the patient had no report of facial tingling, tinnitus, loss of motion, or eye pain.</p></div><div><h3>Conclusion</h3><p>This patient with trigeminal symptoms of cervical origin after an MVC responded well to manual therapy to the cervical spine as part of a combination of services.</p></div>","PeriodicalId":94328,"journal":{"name":"Journal of chiropractic medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40393946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jake C. Halverson DC , Stacey M. Cornelson DC , Quintin W. Murray DC , Norman W. Kettner DC
{"title":"Baseball Injury Resulting in Type III Salter-Harris Fracture of the First Proximal Phalangeal Base: A Case Report","authors":"Jake C. Halverson DC , Stacey M. Cornelson DC , Quintin W. Murray DC , Norman W. Kettner DC","doi":"10.1016/j.jcm.2021.12.006","DOIUrl":"10.1016/j.jcm.2021.12.006","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this report is to describe the clinical, radiographic, and diagnostic ultrasound findings in a patient who sustained a type III Salter-Harris fracture of the first proximal phalanx.</p></div><div><h3>Clinical Features</h3><p><span>A 14-year-old male baseball player presented to a chiropractic<span><span> clinic with a 2-day history of proximal thumb pain, which began following a forceful hyperabduction injury while sliding into base. Thenar swelling was evident on clinical examination, and both active and passive thumb motions were painful in all directions. Radiography revealed a type III Salter-Harris fracture of the first proximal phalangeal base. Additionally, diagnostic </span>ultrasonography demonstrated a probable high-grade </span></span>ulnar collateral ligament<span> sprain. No further displacement of the fracture fragment was visualized with radial deviation stress.</span></p></div><div><h3>Intervention and Outcome</h3><p>The patient was referred to a pediatric<span><span> hand orthopedic specialist for consultation and </span>treatment.</span></p></div><div><h3>Conclusion</h3><p><span>Salter-Harris III fractures of the thumb base warrant special attention to various clinical and imaging features, which may affect patient outcomes. Fracture characterization with radiography is essential in determining the proper management. Ultrasonography and magnetic resonance imaging may be useful in the evaluation of concomitant </span>soft tissue injuries, as demonstrated in this case report.</p></div>","PeriodicalId":94328,"journal":{"name":"Journal of chiropractic medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77176890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amr A. Abdel-aziem PhD , Osama R. Abdelraouf PhD , Heba M.Y. El-Basatiny PhD , Amira H. Draz PhD
{"title":"The Effects of Stabilization Exercises Combined With Pelvic Floor Exercise in Women With Nonspecific Low Back Pain: A Randomized Clinical Study","authors":"Amr A. Abdel-aziem PhD , Osama R. Abdelraouf PhD , Heba M.Y. El-Basatiny PhD , Amira H. Draz PhD","doi":"10.1016/j.jcm.2021.12.008","DOIUrl":"10.1016/j.jcm.2021.12.008","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this study was to investigate the effects of stabilization exercises (SEs) combined with pelvic floor muscle (PFM) exercises versus SE alone on pain intensity, functional disability, and static and dynamic endurance of trunk muscles in women with nonspecific low back pain (LBP).</p></div><div><h3>Methods</h3><p>A total of 48 women with nonspecific LBP (26-45 years) participated in the study. They were randomly allocated into 2 groups. Group A received SEs combined with PFM exercises and physical therapy modalities, and group B received the same intervention without PFM exercises for 6 successive weeks (3 times/wk). Pain intensity, functional disability, and static and dynamic trunk muscle endurance were measured before and after treatment program.</p></div><div><h3>Results</h3><p>After treatment, both groups revealed significant improvements in pain intensity and functional disability scores (<em>P</em> ˂ .05), and significant increases in static and dynamic endurance of trunk flexor and extensor muscles (<em>P</em> ˂ .05). Moreover, there was higher significance in group A compared to group B regarding pain intensity, functional disability scores, and static and dynamic endurance of trunk muscles (<em>P</em> ˂ .05).</p></div><div><h3>Conclusion</h3><p>In this study, the addition of PFM exercise to the SE and physical therapy modalities was more effective in reducing pain intensity, improving functional disability, and increasing the static and dynamic trunk muscle endurance in women with nonspecific LBP compared to SE alone.</p></div>","PeriodicalId":94328,"journal":{"name":"Journal of chiropractic medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80226758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher J. Hodgetts MPhysio, Timothy McLeish BSc, BClinChiro, Emily Thomas BSc, Bruce F. Walker DrPH
{"title":"Association Between Chiropractic Students’ Hand-Eye Coordination or General Self-efficacy and Their Performance on a Spinal Manipulative Therapy Examination: A Cross-sectional Study","authors":"Christopher J. Hodgetts MPhysio, Timothy McLeish BSc, BClinChiro, Emily Thomas BSc, Bruce F. Walker DrPH","doi":"10.1016/j.jcm.2021.12.011","DOIUrl":"10.1016/j.jcm.2021.12.011","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this study was to investigate the association between either hand-eye coordination (HEC) or general self-efficacy (GSE) and spinal-manipulative-therapy (SMT) exam scores. We also measured the interrater reliability of the SMT marking criteria used in our study.</p></div><div><h3>Methods</h3><p><span>Third-year chiropractic students were recruited from the chiropractic spinal technique course at Murdoch University. They completed an alternate-hand wall-toss test to assess HEC and a questionnaire to evaluate GSE. </span>Linear regression models were used to assess the relationships between HEC and GSE on manual-therapy exam scores. Two assessors scored the examination, allowing the investigation of interrater reliability for the SMT marking criteria.</p></div><div><h3>Results</h3><p>A total of 33 male and 31 female students, aged 20 to 44 years, completed both the GSE questionnaire and the SMT examination, but only 28 women also completed the HEC test. Male participants had higher scores on both HEC (9.4 additional catches, <em>P</em> < 0.001) and SMT (6.7%, <em>P</em> = .01) compared to female participants. There was no statistically significant relationship between HEC and SMT (<em>P</em> = .932). However, there was a linear relationship between GSE and SMT when adjusted for sex (<em>P</em><span> = .032). Furthermore, the intraclass correlation coefficient for the marking criteria was moderate to good, at 0.77 (95% confidence interval, 0.63-0.86).</span></p></div><div><h3>Conclusion</h3><p>These preliminary results suggest that when adjusted for sex, a student's GSE may be related to their SMT exam scores. The alternate-hand wall-toss test was not correlated with SMT scores, but other HEC metrics may have a relationship.</p></div>","PeriodicalId":94328,"journal":{"name":"Journal of chiropractic medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72739697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exercise, Manipulative Therapy, and Physical Modalities in the Treatment of Notalgia Paresthetica: A Case Report","authors":"Selin Ozen MBBS, BSc, Sacide NurSaracgil Cosar MD, Seyhan Sozay MD","doi":"10.1016/j.jcm.2021.12.010","DOIUrl":"10.1016/j.jcm.2021.12.010","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this case report is to describe the care of a patient with notalgia paresthetica (NP).</p></div><div><h3>Clinical Features</h3><p>A 61-year-old man presented with a 7-year history of upper back pain, concentrated in the right periscapular region. Physical examination revealed a hyperpigmented area in the right dorsal paravertebral and infrascapular region with local paraesthesia. After investigations, a diagnosis of NP was made.</p></div><div><h3>Intervention and Outcome</h3><p>An exercise program including back and shoulder stretching and shoulder strengthening exercises, and transcutaneous electrical nerve stimulation resulting in a reduction of symptoms.</p></div><div><h3>Conclusion</h3><p>In the case described here, the patient's symptoms regressed when treated conservatively with exercise and physical therapy modalities.</p></div>","PeriodicalId":94328,"journal":{"name":"Journal of chiropractic medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73903780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Gevers-Montoro DC, MSc , Kelvin J. Murray DC, PhD , Beatriz Santamaría DC, PT , Gema Dominguez-Vera DPM , Luis Álvarez-Galovich MD, PhD , Dein Vindigni DC , Michael F. Azari DC, PhD , Arantxa Ortega de Mues PhD , Aurora Castro-Mendez DPM, PhD
{"title":"Combined Chiropractic and Podiatric Treatment for Chronic Low Back Pain Concomitant With a Unilateral Pronated Foot: Protocol for a Multicenter Pilot Randomized Controlled Trial","authors":"Carlos Gevers-Montoro DC, MSc , Kelvin J. Murray DC, PhD , Beatriz Santamaría DC, PT , Gema Dominguez-Vera DPM , Luis Álvarez-Galovich MD, PhD , Dein Vindigni DC , Michael F. Azari DC, PhD , Arantxa Ortega de Mues PhD , Aurora Castro-Mendez DPM, PhD","doi":"10.1016/j.jcm.2021.12.012","DOIUrl":"10.1016/j.jcm.2021.12.012","url":null,"abstract":"<div><h3>Objective</h3><p><span>The purpose of this article is to describe a protocol to examine the feasibility of combining podiatric orthotic<span> treatment with multimodal </span></span>chiropractic treatment to treat chronic low back pain (CLBP) in those with a functional short leg on the same side as a unilateral pronated foot.</p></div><div><h3>Methods</h3><p>This is a protocol for a multicenter feasibility 2-arm parallel randomized controlled trial<span>. One hundred and thirty-two adults with CLBP and a functional short leg on the same side as a unilateral pronated foot are to be recruited in Melbourne, Australia, and Madrid and Seville, Spain. Forty-four participants at each site are to be randomized to multimodal chiropractic treatment including spinal manipulation or to multimodal chiropractic treatment also involving spinal manipulation, together with podiatric custom-made orthoses. Chiropractic visits are to comprise 12 treatments over 4 weeks. Outcome measures will be recruitment, compliance, costs, CLBP-related disability, and perceived low back pain.</span></p></div><div><h3>Results</h3><p>Feasibility results will be reported in text format and the clinical data reported using descriptive statistics focusing on any clinically significant results.</p></div><div><h3>Conclusion</h3><p>This protocol describes a feasibility study for assessing the combination of podiatric orthotic treatment with multimodal chiropractic treatment to treat CLBP in those with a functional short leg on the same side as a unilateral pronated foot.</p></div>","PeriodicalId":94328,"journal":{"name":"Journal of chiropractic medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77054271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernanda F. Fuhro MS, Felipe R.C. Fagundes PhD, Ana Carolina T. Manzoni MS, Cristina M.N. Cabral PhD
{"title":"Discriminative and Predictive Analysis of the Brazilian Version of the Örebro Musculoskeletal Pain Screening Questionnaire (ÖMPSQ) Short-Form in Patients With Low Back Pain","authors":"Fernanda F. Fuhro MS, Felipe R.C. Fagundes PhD, Ana Carolina T. Manzoni MS, Cristina M.N. Cabral PhD","doi":"10.1016/j.jcm.2021.12.009","DOIUrl":"10.1016/j.jcm.2021.12.009","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this study was to analyze the discriminative and predictive validity of the Brazilian Portuguese version of the Örebro Musculoskeletal Pain Screening Questionnaire Short-Form (ÖMPSQ-Short).</p></div><div><h3>Methods</h3><p><span>In this prospective longitudinal cohort study, the ÖMPSQ-Short was administered to 150 patients with acute, subacute, and chronic nonspecific low back pain. A 6-month follow-up was also completed to assess the predictive ability of the questionnaire for risk of pain, disability, and absence from work. The Roland-Morris disability questionnaire, </span>pain numerical rating scale, and additional questions related to work and absence from work were also used.</p></div><div><h3>Results</h3><p><span><span>The ÖMPSQ-Short cutoff point was determined by analyzing the receiver operating characteristic curve, sensitivity, and specificity, which yielded a value of 44 points for the Brazilian population. Analysis of the 2 × 2 contingency tables showed that the ÖMPSQ-Short correctly classified high-risk patients with pain. Predictive capacity was assessed by univariate </span>linear regression analysis. The ÖMPSQ-Short was able to predict pain, disability, and absence from work </span>in patients with acute pain and disability in patients with subacute pain, and disability and absence from work in patients with chronic pain, but with a small predictive capacity.</p></div><div><h3>Conclusion</h3><p>The ÖMPSQ-Short cutoff demonstrated the ability to classify patients with low and high risk of involvement of psychosocial factors. However, due to its small predictive capacity, we suggest that the ÖMPSQ-Short should not be used to predict pain, disability, and absence from work over 6 months. However, we recommend using it as a guide to discuss the patient's clinical condition.</p></div>","PeriodicalId":94328,"journal":{"name":"Journal of chiropractic medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84741805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brett R. Martin DC, MSAc, MPH , Joshua Richardson DC
{"title":"An Exploratory Review of Potential Adjunct Therapies for the Treatment of Coronavirus Infections","authors":"Brett R. Martin DC, MSAc, MPH , Joshua Richardson DC","doi":"10.1016/j.jcm.2021.12.005","DOIUrl":"10.1016/j.jcm.2021.12.005","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this exploratory review was to examine vitamin D, zinc, vitamin A, elderberry (<em>Sambucus nigra</em>), garlic (<em>Allium sativum</em>), licorice (<em>Glycyrrhiza glabra</em>), stinging nettle (<em>Urtica dioica</em>), <em>N</em>-acetylcysteine, quercetin, and selenium as potential adjunct therapies for the treatment of coronavirus infections.</p></div><div><h3>Methods</h3><p>A search of PubMed was performed for articles published from 2005 to 2021. Keywords searched were “zinc,” “vitamin A,” “vitamin D,” “<em>Sambucus nigra</em>,” “<em>Allium sativum</em>,” “<em>Glycyrrhiza glabra</em>,” “<em>Urtica dioica</em>,” “<em>N</em>-acetylcysteine,” “quercetin,” “selenium,” and “coronavirus.”</p></div><div><h3>Results</h3><p>There were 47 articles selected for this review. Findings included that vitamin D, zinc, vitamin A, <em>S. nigra, A. sativum, G. glabra, U. dioica, N</em>-acetylcysteine, quercetin, and selenium have been shown to produce antiinflammatory, immunostimulatory, or antiviral effects that may enhance the actions of standard therapeutics for the treatment of coronavirus infections. Specific to effects against COVID-19, we found research articles related to the effects of only vitamin D, zinc, <em>G. glabra</em>, quercetin, and selenium.</p></div><div><h3>Conclusion</h3><p>We identified nonpharmaceutical supplements (vitamin D, zinc, vitamin A, <em>S. nigra, A. sativum, G. glabra</em>, and <em>U. dioica)</em> which may have potential to provide support for those with coronavirus infections. However, rigorous clinical studies need to be performed before any clinical recommendations can be made.</p></div>","PeriodicalId":94328,"journal":{"name":"Journal of chiropractic medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39600198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}