Applied materials today最新文献

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Self-biomineralized in situ injectable CaSO4 nanorods-enriched collagen-hyaluronic acid composite hydrogels for biomimetic bone reconstruction in a minimally invasive manner 自生物矿化原位注射富含CaSO4纳米棒的胶原-透明质酸复合水凝胶用于微创方式的仿生骨重建
Applied materials today Pub Date : 2023-02-01 DOI: 10.1016/j.apmt.2022.101693
Xingzhu Liu, Yajie Zhang, Zahid Hussain, Penghui Zheng, Mingsheng Xu, Hongbo Zhao, Yuanshan Liu, Yi Cao, Ismat Ullah, Akiyoshi Osaka, Renjun Pei
{"title":"Self-biomineralized in situ injectable CaSO4 nanorods-enriched collagen-hyaluronic acid composite hydrogels for biomimetic bone reconstruction in a minimally invasive manner","authors":"Xingzhu Liu, Yajie Zhang, Zahid Hussain, Penghui Zheng, Mingsheng Xu, Hongbo Zhao, Yuanshan Liu, Yi Cao, Ismat Ullah, Akiyoshi Osaka, Renjun Pei","doi":"10.1016/j.apmt.2022.101693","DOIUrl":"https://doi.org/10.1016/j.apmt.2022.101693","url":null,"abstract":"In situ injectable natural polymer-based hydrogels can be utilized to fill irregular defects and promote tissue regeneration. However, most hydrogels showed limited ability for self-biomineralization and can not guide the formation of new bone. Herein, according to the challenges encountered in advancing materials to clinical research, an injectable collagen-hyaluronic acid (Col-HA) hydrogel embedded with calcium sulfate nanorods (CSN) was developed via a bio-orthogonal reaction between norbornene (Nb) and tetrazine (Tz). The formulated [email protected] composite hydrogels not only have the potential to enhance cell adhesion and proliferation, but also serve as the system to control Ca2+ release. This composite hydrogel displayed impressive injectability, allowing straightforward in situ injection and subsequent adaption of composite hydrogels to irregularly shaped bone defects. CSN-incorporated composite hydrogels facilitate self-biomineralization, thereby fast-forming bone-like hydroxyapatite (HAp) within the hydrogel. Furthermore, Ca2+ released in a steady and sustained way from the composite hydrogels stimulated the differentiation of preosteoblasts, and promoted in situ bone growth. Our findings suggested that [email protected] composite hydrogels can successfully mediate the optimized CSN degradation, effectively accelerate HAp formation, and boost in situ bone development via the minimally invasive application.","PeriodicalId":94299,"journal":{"name":"Applied materials today","volume":"204 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136097246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polyphenol-Coordinated Supramolecular Hydrogel as a Promising “One-Stop-Shop” Strategy for Acute Infected Wound Treatment 多酚配位超分子水凝胶作为急性感染伤口治疗的“一站式”策略
Applied materials today Pub Date : 2022-07-28 DOI: 10.1016/j.apmt.2022.101586
Jie Hu, Rui Chen, Zhenglin Li, Fenzan Wu, Yanhong Yang, Yanhong Yang, Yu Yang, Yu Yang, Xiaokun Li, Jian Xiao
{"title":"Polyphenol-Coordinated Supramolecular Hydrogel as a Promising “One-Stop-Shop” Strategy for Acute Infected Wound Treatment","authors":"Jie Hu, Rui Chen, Zhenglin Li, Fenzan Wu, Yanhong Yang, Yanhong Yang, Yu Yang, Yu Yang, Xiaokun Li, Jian Xiao","doi":"10.1016/j.apmt.2022.101586","DOIUrl":"https://doi.org/10.1016/j.apmt.2022.101586","url":null,"abstract":"","PeriodicalId":94299,"journal":{"name":"Applied materials today","volume":"29 1","pages":"101586-101586"},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147922300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Intestinal delivery of ROS-scavenging carbonized polymer dots for full-course treatment of acute and chronic radiation enteritis 清除活性氧的碳化聚合物微粒在急性和慢性放射性肠炎全程治疗中的应用
Applied materials today Pub Date : 2022-06-08 DOI: 10.1016/j.apmt.2022.101544
Jiaxin Zhang, Mingxi Yang, Xiaoduo Tang, Shuang Li, Junhu Zhang, Laijin Lu, Quan Wang, Yang Bai
{"title":"Intestinal delivery of ROS-scavenging carbonized polymer dots for full-course treatment of acute and chronic radiation enteritis","authors":"Jiaxin Zhang, Mingxi Yang, Xiaoduo Tang, Shuang Li, Junhu Zhang, Laijin Lu, Quan Wang, Yang Bai","doi":"10.1016/j.apmt.2022.101544","DOIUrl":"https://doi.org/10.1016/j.apmt.2022.101544","url":null,"abstract":"","PeriodicalId":94299,"journal":{"name":"Applied materials today","volume":"28 1","pages":"101544-101544"},"PeriodicalIF":0.0,"publicationDate":"2022-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147896364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Mechanochemical synthesis of enzyme@covalent organic network nanobiohybrids enzyme@covalent有机网状纳米生物杂化物的机械化学合成
Applied materials today Pub Date : 2022-01-18 DOI: 10.1016/j.apmt.2022.101381
Yushuai Jiao, Nan Yan, Zhenhua Wu, Xueying Wang, Jiaxu Zhang, Boyu Zhang, Shouying Huang, Jiafu Shi
{"title":"Mechanochemical synthesis of enzyme@covalent organic network nanobiohybrids","authors":"Yushuai Jiao, Nan Yan, Zhenhua Wu, Xueying Wang, Jiaxu Zhang, Boyu Zhang, Shouying Huang, Jiafu Shi","doi":"10.1016/j.apmt.2022.101381","DOIUrl":"https://doi.org/10.1016/j.apmt.2022.101381","url":null,"abstract":"","PeriodicalId":94299,"journal":{"name":"Applied materials today","volume":"26 1","pages":"101381-101381"},"PeriodicalIF":0.0,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147906719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Engineered nanogels simultaneously implement HDAC inhibition and chemotherapy to boost antitumor immunity via pyroptosis 工程纳米凝胶同时实施HDAC抑制和化疗,通过焦亡来增强抗肿瘤免疫
Applied materials today Pub Date : 2022-01-11 DOI: 10.1016/j.apmt.2022.101363
De‐Run Chen, Yuan Gao, Yao Xiao, Shu‐Cheng Wan, Zhi‐Zhong Wu, Shuo Wang, Xianbin Ma, Zhigang Xu, Zhi‐Jun Sun
{"title":"Engineered nanogels simultaneously implement HDAC inhibition and chemotherapy to boost antitumor immunity via pyroptosis","authors":"De‐Run Chen, Yuan Gao, Yao Xiao, Shu‐Cheng Wan, Zhi‐Zhong Wu, Shuo Wang, Xianbin Ma, Zhigang Xu, Zhi‐Jun Sun","doi":"10.1016/j.apmt.2022.101363","DOIUrl":"https://doi.org/10.1016/j.apmt.2022.101363","url":null,"abstract":"","PeriodicalId":94299,"journal":{"name":"Applied materials today","volume":"26 1","pages":"101363-101363"},"PeriodicalIF":0.0,"publicationDate":"2022-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147893570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Targeted delivery of Fenton reaction packages and drugs for cancer theranostics 靶向递送芬顿反应包和癌症治疗药物
Applied materials today Pub Date : 2022-01-06 DOI: 10.1016/j.apmt.2021.101353
Xiao Fu, Yulin Zhang, Gaorui Zhang, Xingang Li, Shilei Ni, Jiwei Cui
{"title":"Targeted delivery of Fenton reaction packages and drugs for cancer theranostics","authors":"Xiao Fu, Yulin Zhang, Gaorui Zhang, Xingang Li, Shilei Ni, Jiwei Cui","doi":"10.1016/j.apmt.2021.101353","DOIUrl":"https://doi.org/10.1016/j.apmt.2021.101353","url":null,"abstract":"","PeriodicalId":94299,"journal":{"name":"Applied materials today","volume":"26 1","pages":"101353-101353"},"PeriodicalIF":0.0,"publicationDate":"2022-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147906187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Crystal phase-driven copolymerization of CO2 and cyclohexene oxide in Prussian blue analogue nanosheets 普鲁士蓝模拟纳米片中CO2和环氧环己烯的晶体相驱动共聚
Applied materials today Pub Date : 2022-01-06 DOI: 10.1016/j.apmt.2021.101352
Weibin Zhang, Touwen Fan, Zhen Yang, Ruipeng Yu, Xinjuan Zeng, Yonghang Xu, Min Zhang, Huawen Hu, Jian Zhen Ou, Lirong Zheng
{"title":"Crystal phase-driven copolymerization of CO2 and cyclohexene oxide in Prussian blue analogue nanosheets","authors":"Weibin Zhang, Touwen Fan, Zhen Yang, Ruipeng Yu, Xinjuan Zeng, Yonghang Xu, Min Zhang, Huawen Hu, Jian Zhen Ou, Lirong Zheng","doi":"10.1016/j.apmt.2021.101352","DOIUrl":"https://doi.org/10.1016/j.apmt.2021.101352","url":null,"abstract":"","PeriodicalId":94299,"journal":{"name":"Applied materials today","volume":"26 1","pages":"101352-101352"},"PeriodicalIF":0.0,"publicationDate":"2022-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147891599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Bioinspired, injectable, tissue-adhesive and antibacterial hydrogel for multiple tissue regeneration by minimally invasive therapy 生物启发,可注射,组织粘连和抗菌水凝胶,用于多种组织再生的微创治疗
Applied materials today Pub Date : 2021-12-03 DOI: 10.1016/j.apmt.2021.101290
Feifei Zhou, Yuan Yang, Wenjing Zhang, Shuyu Liu, Atik Badshah Shaikh, Lei Yang, Yuxiao Lai, Hongwei Ouyang, Weimin Zhu
{"title":"Bioinspired, injectable, tissue-adhesive and antibacterial hydrogel for multiple tissue regeneration by minimally invasive therapy","authors":"Feifei Zhou, Yuan Yang, Wenjing Zhang, Shuyu Liu, Atik Badshah Shaikh, Lei Yang, Yuxiao Lai, Hongwei Ouyang, Weimin Zhu","doi":"10.1016/j.apmt.2021.101290","DOIUrl":"https://doi.org/10.1016/j.apmt.2021.101290","url":null,"abstract":"","PeriodicalId":94299,"journal":{"name":"Applied materials today","volume":"26 1","pages":"101290-101290"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147881820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 54
Nitrogen and Boron Dual-Doped Graphene Quantum Dots for Near-Infrared Second Window Imaging and Photothermal Therapy. 用于近红外第二窗口成像和光热治疗的氮和硼双掺杂石墨烯量子点。
Applied materials today Pub Date : 2019-03-01 Epub Date: 2018-12-06 DOI: 10.1016/j.apmt.2018.11.011
Hui Wang, Qingxin Mu, Kui Wang, Richard A Revia, Charles Yen, Xinyu Gu, Bowei Tian, Jun Liu, Miqin Zhang
{"title":"Nitrogen and Boron Dual-Doped Graphene Quantum Dots for Near-Infrared Second Window Imaging and Photothermal Therapy.","authors":"Hui Wang, Qingxin Mu, Kui Wang, Richard A Revia, Charles Yen, Xinyu Gu, Bowei Tian, Jun Liu, Miqin Zhang","doi":"10.1016/j.apmt.2018.11.011","DOIUrl":"10.1016/j.apmt.2018.11.011","url":null,"abstract":"<p><p>Fluorescence imaging of biological systems in the second near-infrared window (NIR-II) has recently drawn much attention because of its negligible background noise of autofluorescence and low tissue scattering. Here we present a new NIR-II fluorescent agent, graphene quantum dots dual-doped with both nitrogen and boron (N-B-GQDs). N-B-GQDs have an ultra-small size (~ 5 nm), are highly stable in serum, and demonstrate a peak fluorescent emission at 1000 nm and high photostability. In addition to the NIR-II imaging capability, N-B-GQDs efficiently absorb and convert NIR light into heat when irradiated by an external NIR source, demonstrating a photothermal therapeutic effect that kills cancer cells in vitro and completely suppresses tumor growth in a glioma xenograft mouse model. N-B-GQDs demonstrate a safe profile, prolonged blood half-life, and rapid excretion in mice, which are the characteristics favorable for in vivo biomedical applications.</p>","PeriodicalId":94299,"journal":{"name":"Applied materials today","volume":"14 ","pages":"108-117"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752708/pdf/nihms-1516204.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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