{"title":"Idiopathic lymphocytic-eosinophilic pleural effusion with clinical response to corticosteroids: a case report.","authors":"Justin Jin Hao Jang, Chia Meng Teoh, Pyng Lee","doi":"10.4103/singaporemedj.SMJ-2025-004","DOIUrl":"https://doi.org/10.4103/singaporemedj.SMJ-2025-004","url":null,"abstract":"","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mei Ling Tan, Elliot Eu, Sylvia Teo, John Wah Lim, Shiu Hong Wong
{"title":"Re-employment medical examinations: assessing fitness to work in ageing healthcare workers.","authors":"Mei Ling Tan, Elliot Eu, Sylvia Teo, John Wah Lim, Shiu Hong Wong","doi":"10.4103/singaporemedj.SMJ-2024-192","DOIUrl":"https://doi.org/10.4103/singaporemedj.SMJ-2024-192","url":null,"abstract":"","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring adherence to antidiabetic medications in Singapore primary care: a comparison of four models of proportion of days covered.","authors":"Hui Rei Yap, Wern Ee Tang","doi":"10.4103/singaporemedj.SMJ-2024-072","DOIUrl":"https://doi.org/10.4103/singaporemedj.SMJ-2024-072","url":null,"abstract":"<p><strong>Introduction: </strong>There is currently no standardised approach to calculate and report proportion of days covered (PDC), a medication adherence measure. We aimed to assess adherence to antidiabetic medications by applying four PDC models to a primary care database and examine the factors associated with medication adherence.</p><p><strong>Methods: </strong>Four models were used to calculate PDC for 789 patients with diabetes mellitus (DM) using the average PDC method. Models P1 and P2 incorporated prescribed and dispensed data, whereas models D1 and D2 used dispensed data only. Models P1 and D1 used an interval-based method, whereas models P2 and D2 used a prescription-based method. Gender, age at recruitment, race, number of chronic diseases, years of DM, glycated haemoglobin (HbA1c) levels and number of antidiabetic medication classes were tested in a univariate analysis. Stepwise selection method was used in the multivariate logistic regression model.</p><p><strong>Results: </strong>The proportion of adherent patients (PDC ≥80%) was 64.1% for model P1, 73.9% for P2, 66.5% for D1, and 87.3% for D2. Patients with PDC <80% were more likely to have HbA1c ≥9% (odds ratios 2.54 [P1], 2.69 [P2], 2.48 [D1], and 3.33 [D2]). Additionally, PDC <80% was associated with Malay or Indian ethnicity and having four or more chronic diseases.</p><p><strong>Conclusion: </strong>The PDC models that incorporate prescribed data and use interval-based methods may result in more patients being classified as having poor adherence. Compared to the other models, we postulate that model P2 may provide the most accurate estimate of adherence, as it takes into account the prescribers' intent by including prescribed data and changes in medication regimens by using prescription-based method.</p>","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lydia Wan Zhen Lim, Kai Yee Toh, Alex Richard Cook, Jonathan Wei Jie Lee, Jeremy Fung Yen Lim
{"title":"Public knowledge, awareness and perception of gut microbiome and faecal microbiota transplantation in Singapore: a survey study.","authors":"Lydia Wan Zhen Lim, Kai Yee Toh, Alex Richard Cook, Jonathan Wei Jie Lee, Jeremy Fung Yen Lim","doi":"10.4103/singaporemedj.SMJ-2024-076","DOIUrl":"10.4103/singaporemedj.SMJ-2024-076","url":null,"abstract":"<p><strong>Introduction: </strong>Despite the exponential increase in microbiome research, knowledge and beliefs about the gut microbiome and faecal microbiota transplantation (FMT) remain unclear. The aim of this study was to identify the extent of knowledge, awareness and perception among the general public regarding the gut microbiome and FMT.</p><p><strong>Methods: </strong>An online questionnaire on knowledge and beliefs about the gut microbiome and FMT was administered to 1831 participants. Data analysis software was used to generate descriptive statistics and explore associations between knowledge and sociodemographic variables.</p><p><strong>Results: </strong>Even though only 33% of participants had heard of the gut microbiome, more than 92% had consumed probiotic drinks or supplements. While 85% had not heard of the FMT procedure, 72% of respondents would consider having FMT to treat Clostridioides difficile infection (CDI). Willingness to receive FMT depended mainly on recommendation from healthcare providers (77%). Knowledge and awareness regarding the gut microbiome and FMT were relatively low, despite most participants having prior gut health-related behaviours.</p><p><strong>Conclusion: </strong>This study identified the public's perceptions of FMT and the potential barriers to its uptake. Insights from the study highlight the need for health education to enhance acceptance of FMT and the importance of using information supported by medical professionals to immunise the public against poorly validated science.</p>","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Singapore medical journalPub Date : 2025-06-01Epub Date: 2025-06-13DOI: 10.4103/singaporemedj.SMJ-2025-117
Silin Kuang, See Meng Khoo
{"title":"Response to Comments on: obstructive sleep apnoea and nocturnal atrial fibrillation in patients with ischaemic heart disease.","authors":"Silin Kuang, See Meng Khoo","doi":"10.4103/singaporemedj.SMJ-2025-117","DOIUrl":"https://doi.org/10.4103/singaporemedj.SMJ-2025-117","url":null,"abstract":"","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":"66 6","pages":"351"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Singapore medical journalPub Date : 2025-06-01Epub Date: 2025-06-13DOI: 10.4103/singaporemedj.SMJ-2022-110
Wen Hann Chow, Kai Xiang Zhang, Wei Keong Daniel Chan
{"title":"Approach to premature thelarche in children.","authors":"Wen Hann Chow, Kai Xiang Zhang, Wei Keong Daniel Chan","doi":"10.4103/singaporemedj.SMJ-2022-110","DOIUrl":"https://doi.org/10.4103/singaporemedj.SMJ-2022-110","url":null,"abstract":"","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":"66 6","pages":"338-342"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Singapore medical journalPub Date : 2025-06-01Epub Date: 2025-06-13DOI: 10.4103/singaporemedj.SMJ-2025-110
Amir Reza Akbari, Benyamin Alam
{"title":"Comments on: obstructive sleep apnoea and nocturnal atrial fibrillation in patients with ischaemic heart disease.","authors":"Amir Reza Akbari, Benyamin Alam","doi":"10.4103/singaporemedj.SMJ-2025-110","DOIUrl":"https://doi.org/10.4103/singaporemedj.SMJ-2025-110","url":null,"abstract":"","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":"66 6","pages":"350"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Singapore medical journalPub Date : 2025-06-01Epub Date: 2024-01-12DOI: 10.4103/singaporemedj.SMJ-2023-068
Han-Kwee Ho, Eileen Yi-Ling Koh, Adina Abdullah, Ngiap-Chuan Tan
{"title":"Health literacy and self-care among patients with chronic kidney disease in a primary care setting.","authors":"Han-Kwee Ho, Eileen Yi-Ling Koh, Adina Abdullah, Ngiap-Chuan Tan","doi":"10.4103/singaporemedj.SMJ-2023-068","DOIUrl":"10.4103/singaporemedj.SMJ-2023-068","url":null,"abstract":"<p><strong>Introduction: </strong>The study objective was to determine the levels of self-care and health literacy (HL) and their associations among patients with chronic kidney disease (CKD).</p><p><strong>Methods: </strong>This was a cross-sectional, questionnaire-based study conducted in a public primary care setting in Singapore. A total of 289 participants aged 21-80 years with hypertension were recruited. Self-care profiles were measured using the Hypertension Self-Care Profile (HTN-SCP; range 0-240, domain range 0-80). Health literacy was measured using the Short-Form Health Literacy Scale (HLS-SF12; range 0-50, limited literacy ≤33).</p><p><strong>Results: </strong>The mean self-care score was 182.7 (standard deviation [SD] 23.2). The median HL score was 34.7 (interquartile range [IQR] 31.9-40.3), and 31.1% of participants had limited HL. Self-care was not associated with age, CKD status, household income and education, but was associated with gender and HL score. In the final regression model, lower HL scores (adjusted β = 1.03, 95% confidence interval [CI] 0.7 to 1.36, P < 0.001) and male gender (adjusted β = -5.29, 95% CI -10.56 to -0.03, P = 0.049) were associated with lower self-care scores. The HL scores were associated with self-care domains of self-efficacy (HL: β = 0.30, 95% CI 0.17 to 0.42, P < 0.001), motivation (HL: β = 0.40, 95% CI 0.26 to 0.53, P < 0.001) and behaviour (HL: β = 0.38, 95% CI 0.26 to 0.50, P < 0.001).</p><p><strong>Conclusion: </strong>Thirty-one percent of the participants had limited HL. Self-care was not associated with age, race, CKD status, household income or education. Male gender and limited HL were associated with lower self-care. Self-care was associated with self-efficacy, motivation and behaviour. Future research could focus on more targeted approaches to improve self-care and HL among patients with CKD.</p>","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":" ","pages":"307-313"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139428219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Singapore medical journalPub Date : 2025-06-01Epub Date: 2025-06-13DOI: 10.4103/singaporemedj.SMJ-2023-248
Wai Keat Lau, Natalie Li Xuan Lim, Ivandito Kuntjoro, Lynette Li San Teo
{"title":"Clinics in diagnostic imaging (223).","authors":"Wai Keat Lau, Natalie Li Xuan Lim, Ivandito Kuntjoro, Lynette Li San Teo","doi":"10.4103/singaporemedj.SMJ-2023-248","DOIUrl":"https://doi.org/10.4103/singaporemedj.SMJ-2023-248","url":null,"abstract":"","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":"66 6","pages":"343-347"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}