Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine最新文献

{"title":"Red blood cell exchange in Hemoglobin Evans: A novel therapeutic avenue for a rare hemoglobinopathy.","authors":"Radheshyam Meher","doi":"10.1016/j.tracli.2025.05.005","DOIUrl":"https://doi.org/10.1016/j.tracli.2025.05.005","url":null,"abstract":"","PeriodicalId":94255,"journal":{"name":"Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic plasma exchange in treatment of autoimmune retinopathy.","authors":"Yigit Baykara, Muharrem Yunce","doi":"10.1016/j.tracli.2025.05.003","DOIUrl":"10.1016/j.tracli.2025.05.003","url":null,"abstract":"","PeriodicalId":94255,"journal":{"name":"Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From 'Aww to Wow': emerging role of transfusion medicine in fecal microbiota transplantation.","authors":"Radheshyam Meher","doi":"10.1016/j.tracli.2025.05.004","DOIUrl":"10.1016/j.tracli.2025.05.004","url":null,"abstract":"","PeriodicalId":94255,"journal":{"name":"Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transfusion medicine beyond earth: preparing for human blood management in space missions.","authors":"Yamac Akgun","doi":"10.1016/j.tracli.2025.05.002","DOIUrl":"10.1016/j.tracli.2025.05.002","url":null,"abstract":"","PeriodicalId":94255,"journal":{"name":"Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using SARS-CoV-2 red cell kodecytes to assess vaccine-induced immune response to the conserved 1147-58 region of the spike protein in Indian blood donors: exploring the potential role of blood transfusion services in population surveillance.","authors":"Suvro Sankha Datta, Aniruddha Hazra, Najla Haneefa Basheela, Kaushik Gupta, Pradip Kumar Mondal, Elena Aliper, Nicolai V Bovin, Stephen M Henry","doi":"10.1016/j.tracli.2025.05.001","DOIUrl":"10.1016/j.tracli.2025.05.001","url":null,"abstract":"<p><strong>Background and objectives: </strong>Blood transfusion services are uniquely poised to take part in the population surveillance study by providing snapshots of the SARS-CoV-2 immunity status among vaccinated blood donors. The immunogenic 1147-58 region of the intact SARS-CoV-2 spike protein is partly spatially hidden. These 1147-58-region-specific antibodies have previously been observed in COVID-19 infected patients but have not been documented in vaccinated individuals. In this study, we aimed to determine the immune response to this conserved region of the spike protein using SARS-CoV-2 red cell kodecytes among vaccinated blood donors.</p><p><strong>Material and methods: </strong>Three hundred fifteen voluntary blood donors of Indian ethnicity vaccinated twice against SARS-CoV-2 who, to their knowledge, had not had COVID-19 infection, were screened using quantitative chemiluminescent (CLIA) SARS-CoV-2 immunoassay (detecting total S1 IgG antibodies by measuring the binding antibody units [BAU]), as well as a SARS-CoV-2 red cell kodecytes assay detecting IgG antibodies specific to the 1147-58 region by column agglutination technique.</p><p><strong>Results: </strong>The CLIA assay was antibody-reactive with 100% of the 315 samples from vaccinated individuals (BAU/mL > 20), of which 311 (98.7%) were considered immune (BAU/mL > 58). Of the 315 CLIA-reactive samples, moderate to strong kodecyte serologic grades were observed for 63.2% (n = 199) of the samples, while 24.8% (n = 78) yielded weak serologic responses, and 12.1% (n = 38) were unreactive against kodecytes.</p><p><strong>Conclusions: </strong>These results show that about 12% of vaccinated individuals do not have detectable antibodies to the conserved 1147-58 region of the SARS-CoV-2 spike protein and suggest that future studies should clarify whether this has biological implications regarding long-term immune protection.</p>","PeriodicalId":94255,"journal":{"name":"Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 8-Model framework: a strategic roadmap for patient blood management implementation- A critical commentary.","authors":"Radheshyam Meher","doi":"10.1016/j.tracli.2025.04.006","DOIUrl":"10.1016/j.tracli.2025.04.006","url":null,"abstract":"","PeriodicalId":94255,"journal":{"name":"Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation challenges and opportunities of platelet inventory models in oncology setting based blood banks.","authors":"Naveen Bansal, Rajbir Kaur Cheema","doi":"10.1016/j.tracli.2025.04.001","DOIUrl":"10.1016/j.tracli.2025.04.001","url":null,"abstract":"","PeriodicalId":94255,"journal":{"name":"Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Restrictive RBC transfusion in the ICU: Trends in clinical adherence.","authors":"Merijn C Reuland, Senta J Raasveld, Alexander P J Vlaar, Marcella C A Müller","doi":"10.1016/j.tracli.2025.04.003","DOIUrl":"10.1016/j.tracli.2025.04.003","url":null,"abstract":"<p><strong>Introduction: </strong>The balance between the risks and benefits of red blood cell (RBC) transfusions in critically ill patients is of ongoing debate. Clinical guidelines suggest a restrictive transfusion strategy with a transfusion hemoglobin trigger of 7 g/dL for most critically ill patients. However, recent literature shows many RBC transfusions are given with a prior hemoglobin above 7 g/dL. We aimed to evaluate adherence to our own transfusion protocol and changes in transfusion policy over time for the entire Intensive Care Unit (ICU) and in subgroups.</p><p><strong>Methods: </strong>Retrospective observational cohort study of patients admitted between 2017 and 2024 to the ICU of Amsterdam UMC. Data was extracted from the electronic health record and the Dutch national quality registry (NICE). Subgroup analysis was done based on referring specialty.</p><p><strong>Results: </strong>In total 24 761 ICU stays were analyzed with 12 064 RBC transfusions in 3444 ICU stays. Median hemoglobin value before RBC transfusion decreased from 7.7 g/dL (1st-3rdquartile 7.1-8.4) in 2017 to 6.8 g/dL ((1st-3rdquartile 6.4-7.3) in 2024 (p < 0.001). This decrease was present in all subgroups. The percentage of RBC transfusions with a prior hemoglobin <7 g/dL increased from 18.8% to 64.8% (p < 0.001).</p><p><strong>Conclusion: </strong>We report the long term successful implementation of a comprehensive restrictive RBC transfusion protocol in a tertiary care ICU, independent of the patient's referring specialty. A median hemoglobin level of 6.8 g/dL before RBC transfusion was reached in 2024.</p>","PeriodicalId":94255,"journal":{"name":"Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fragile beginnings enduring legacy: the blood bag story.","authors":"Manish Raturi, Aaditya Shivhare","doi":"10.1016/j.tracli.2025.04.005","DOIUrl":"10.1016/j.tracli.2025.04.005","url":null,"abstract":"","PeriodicalId":94255,"journal":{"name":"Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the pattern of blood utilization in various obstetric scenarios unfolding within the wall of tertiary care centre: A prospective study from western India.","authors":"Nishith Nayan, Shweta Ranjan, Rakesh Kumar, Jitendra Patel, Nilamben Prajapati, Priyatma Kumari","doi":"10.1016/j.tracli.2025.04.002","DOIUrl":"10.1016/j.tracli.2025.04.002","url":null,"abstract":"<p><strong>Background and objectives: </strong>With increasing demand for blood components being unable to meet the supply in developing countries, there is a need to implement strategies for rational use of blood components. Present study aims to evaluate transfusion practices in obstetric emergencies in a hospital-based blood centre.</p><p><strong>Material and methods: </strong>The study was conducted from November 2020 to October 2021, focussing on obstetric in-patients who requested blood transfusions. Requests were processed and cross-matched following the hospital's transfusion guidelines. The data on clinical conditions and blood transfusion details were analysed to evaluate the use of blood and blood components in relation to the patients' diagnosis.</p><p><strong>Results: </strong>Out of 6,753 obstetric cases admitted, 334 patients requested blood components. Blood components were transfused to 271 (81.1%) patients. Total 927 units were used, out of which 57.1% were packed red blood cells. Most common indications were atonic postpartum haemorrhage (36.8%), placental abruption (23.7%) and placenta previa (16.5%). Crossmatch-to-Transfusion Ratio was 1.5, Transfusion Probability was 81.1%, Transfusion Index was 2.8, and Maximum Blood Ordering Schedule was 4.2.</p><p><strong>Conclusion: </strong>Standard Operating Procedure for an efficient blood ordering policy should be developed and strict adherence to established blood transfusion guidelines must be ensured. Over-ordering can lead to unnecessary reservations and subsequent shortages. Emphasis on appropriate use of blood components to ensure their effective management is crucial.</p>","PeriodicalId":94255,"journal":{"name":"Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}