Reumatologia clinica最新文献

{"title":"Cutaneous and serological profiles of idiopathic inflammatory myopathies in a hispanic population","authors":"Selene Maribel Delgado-Ayala ,&nbsp;Sonia Chávez-Álvarez ,&nbsp;Jorge Ocampo-Candiani ,&nbsp;Miguel Ángel Villarreal-Alarcón ,&nbsp;Dionicio Ángel Galarza-Delgado ,&nbsp;Lourdes Gil-Flores ,&nbsp;David Vega-Morales","doi":"10.1016/j.reumae.2026.502100","DOIUrl":"10.1016/j.reumae.2026.502100","url":null,"abstract":"<div><h3>Introduction</h3><div>In the diagnosis and management of idiopathic inflammatory myopathies, cutaneous manifestations are particularly significant. Clinical signs are often associated with specific autoantibodies and play a role in the classification, treatment, and prognosis of IIM.</div></div><div><h3>Objective</h3><div>Describe the cutaneous clinical presentation, phototype, and autoantibody profiles among Hispanic patients with IIM.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted from January 2015 to November 2022, including 64 patients diagnosed with IIM. Rheumatological and dermatological evaluations were performed, assessing Fitzpatrick phototype and Cutaneous Dermatomyositis Activity and Severity Index (CDASI) scores. Autoantibodies were analyzed using immunoblotting.</div></div><div><h3>Results</h3><div>Dermatomyositis (DM) was the most common subtype (73.4%). Fitzpatrick phototypes IV (59.4%) and III (37.5%) predominated. CDASI scores indicated mild dermatological activity in 60.9% of cases. Cluster analysis identified four patient groups with distinct clinical and serological profiles.</div></div><div><h3>Conclusion</h3><div>IIM have a complex disease expression. Recognizing its heterogeneities can enhance personalized treatment approaches.</div></div>","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"22 3","pages":"Article 502100"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147617293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minor salivary gland biopsy: A less invasive technique and applications","authors":"Mónica Fernández-Castro ,&nbsp;Carolina Merino ,&nbsp;Natalia de la Torre ,&nbsp;Pablo Navarro ,&nbsp;María Machattou ,&nbsp;María Concepción Sánchez-Fernández ,&nbsp;Andrea Liso ,&nbsp;Martín Luz Martín-Fragueiro ,&nbsp;José Luis Rodríguez Carrillo ,&nbsp;Jose Luis Andreu ,&nbsp;Jesús Sanz","doi":"10.1016/j.reumae.2026.502077","DOIUrl":"10.1016/j.reumae.2026.502077","url":null,"abstract":"<div><div>Minor salivary gland biopsy (MSGB) plays a pivotal role in the classification and diagnosis of Sjögren’s disease, one of the most prevalent systemic autoimmune disorders within the spectrum of rheumatic diseases. Furthermore, it provides valuable phenotypic information about the patient, contributes to the assessment of disease prognosis, and serves as a reliable tool for monitoring therapeutic response. MSGB is also useful in the diagnosis of amyloidosis, sarcoidosis, IgG4 disease, or lymphoma. In recent years, less invasive techniques have become increasingly widespread and have been proposed as highly accessible procedures for rheumatologists—straightforward to perform and associated with minimal or no complications. Consequently, MSGB has become a key diagnostic and follow-up tool in the comprehensive management of the disease.</div></div>","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"22 3","pages":"Article 502077"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147489080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of comorbidities and medication use in progressive systemic sclerosis in northeast Mexico","authors":"Jorge Armando Hermosillo-Villafranca ,&nbsp;Maria Joselin Rodarte-Gallegos","doi":"10.1016/j.reumae.2026.502078","DOIUrl":"10.1016/j.reumae.2026.502078","url":null,"abstract":"<div><h3>Background</h3><div>Systemic sclerosis (SSc) is characterized by exuberant fibrosis, caused by severe vasculopathy and vasospasm. Despite the impact of the disease on survival, epidemiological and comorbidity data on SSc are currently limited in Mexico.</div></div><div><h3>Methods</h3><div>Observational, cross-sectional, and descriptive clinical study. Patients with SSc according to the 2013 ACR/EULAR criteria from 2 public healthcare centres in northeastern Mexico from the IMSS were included. Sociodemographic, clinical, and laboratory variables were collected. The prevalence of comorbidities reported by the patients was investigated. Serology, transthoracic ultrasound, and high-resolution chest computed tomography were performed.</div></div><div><h3>Results</h3><div>68 patients with SSc were included: 65 (95.3%) women, with a mean age of 51.5 ± 9.86 years, with the following distribution: 50 (73.5%) limited, 7 (10.3%) diffuse, 11 overlap (16.2%), 22 (32.3%) with systemic arterial hypertension, 14 (20.5%) with obesity.</div></div><div><h3>Conclusions</h3><div>The detection of systemic arterial hypertension, the most frequent comorbidities in multiple populations, could prevent cardiovascular complications.</div></div>","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"22 3","pages":"Article 502078"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147489110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a scale for the assessment of Sexual Dysfunction in Men with Autoimmune Diseases (DS-HAI)","authors":"Pedro Arbey Quevedo Mayorga ,&nbsp;Diana Isabel Muñoz ,&nbsp;Bibiana Andrea Castro ,&nbsp;Daniel Fernández Ávila ,&nbsp;Andrea Gómez ,&nbsp;Mariano Rivero ,&nbsp;Andrés González ,&nbsp;Carlos Yepes ,&nbsp;Laura Kattah Martinez ,&nbsp;Christian Buitrago-Carrascal ,&nbsp;Andrea Criollo Gómez","doi":"10.1016/j.reumae.2026.502073","DOIUrl":"10.1016/j.reumae.2026.502073","url":null,"abstract":"<div><h3>Introduction</h3><div>Men with autoimmune diseases present specific pathophysiological factors such as chronic inflammation, pain, fatigue, endocrine alterations, and the effects of immunosuppressive therapy that may affect sexual function differently than in other populations. Our objective was to develop and validate a scale to measure sexual dysfunction in men with autoimmune diseases.</div></div><div><h3>Methods</h3><div>A quantitative, cross-sectional validation study was conducted. The study encompassed the theoretical construction of the instrument through its application in the target population, in order to evaluate its psychometric properties. Male patients over 18 years of age with a prior diagnosis of an autoimmune disease were included, while those with concomitant psychiatric conditions were excluded. The instrument was developed through three Delphi rounds. Internal reliability was assessed using Cronbach’s alpha coefficient, as well as McDonald’s total omega (ω total) and hierarchical omega (ωh). An exploratory factor analysis was also performed.</div></div><div><h3>Results</h3><div>A final version of the instrument comprising 14 items distributed across two factors was obtained. Cronbach’s alpha coefficient was 0.93, indicating excellent reliability. To confirm and complement this estimate, McDonald’s omega coefficients were calculated. The total omega (ω = 0.95) confirmed high internal consistency, while the hierarchical omega (ωh = 0.77) indicated that a substantial proportion of the total variance was attributable to the general factor, supporting the validity of the identified bifactorial model.</div></div><div><h3>Conclusion</h3><div>The DS-HAI instrument demonstrated adequate psychometric properties for identifying sexual dysfunction in men, revealing a two-dimensional factorial structure.</div></div>","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"22 3","pages":"Article 502073"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147476818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast cancer in the first person in Latin America: A reflection on the role of the rheumatologist in the patient’s integral health","authors":"Deshiré Alpízar-Rodríguez,&nbsp;on behalf of the PANLAR-MUJER","doi":"10.1016/j.reumae.2026.502051","DOIUrl":"10.1016/j.reumae.2026.502051","url":null,"abstract":"","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"22 3","pages":"Article 502051"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147476840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Application of the DETECT algorithm in a cohort of patients with systemic sclerosis”","authors":"Bhumesh Tyagi ,&nbsp;Leelabati Toppo ,&nbsp;Aishwarya Biradar","doi":"10.1016/j.reumae.2026.502075","DOIUrl":"10.1016/j.reumae.2026.502075","url":null,"abstract":"","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"22 3","pages":"Article 502075"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147617302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“DISH-phagia”: Unusual upper cervical involvement of diffuse idiopathic skeletal hyperostosis presenting with long-standing dysphagia","authors":"Inês Santos ,&nbsp;Nádia Martins ,&nbsp;Paulo Monteiro ,&nbsp;Filipe Rodrigues","doi":"10.1016/j.reumae.2026.502072","DOIUrl":"10.1016/j.reumae.2026.502072","url":null,"abstract":"","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"22 3","pages":"Article 502072"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147617288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher artificial intelligence literacy among patients with fibromyalgia syndrome: Results from a cross-sectional survey study","authors":"Gülseren Demir Karakılıç ,&nbsp;Özlem Balbaloğlu ,&nbsp;Şemsinnur Göçer","doi":"10.1016/j.reumae.2026.502098","DOIUrl":"10.1016/j.reumae.2026.502098","url":null,"abstract":"<div><h3>Introduction</h3><div>Health literacy in fibromyalgia syndrome (FMS) has been previously investigated; however, digital and artificial intelligence (AI) literacy remain underexplored in this population. This study aimed to evaluate both e-health and AI literacy in individuals with FMS and to explore factors influencing these competencies, with particular emphasis on AI literacy. Given the central role of digital and AI-related competencies, the study primarily focused on outcomes derived from the E-Health Literacy Scale (eHLS), and Artificial Intelligence Literacy Scale (AILS) scale.</div></div><div><h3>Material and methods</h3><div>This cross-sectional study, conducted between December 2024 and May 2025, included 106 FMS patients and 106 age- and sex-matched healthy controls. Participants completed the Revised Fibromyalgia Impact Questionnaire (rFIQ), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), eHLS, and -AILS. Adequate cognitive function was confirmed through clinical interview, absence of cognitive complaints, and the ability to complete questionnaires independently. Between-group comparisons and correlation analyses were performed.</div></div><div><h3>Results</h3><div>Although eHLS scores were slightly higher in the FMS group, the difference was not statistically significant (<em>p</em> <!-->=<!--> <!-->0.074). AILS scores were significantly greater among FMS patients compared to controls (<em>p</em> <!-->&lt;<!--> <!-->0.001). No correlation was observed between eHLS or AILS and symptom severity. However, both measures demonstrated a shared digital competency profile, as reflected by their strong mutual correlation. However, a strong positive correlation was found between eHLS and AILS (<em>r</em> <!-->=<!--> <!-->0.736, <em>p</em> <!-->&lt;<!--> <!-->0.001).</div></div><div><h3>Conclusions</h3><div>This is the first study to assess AI literacy in FMS using a validated scale. The observed link between digital and AI literacy highlights their intertwined roles in chronic disease management. These results underscore the need for future interventions focused on enhancing digital competencies among individuals with FMS. Future research should also incorporate broader patient-centered outcomes, including quality of life, treatment adherence, disease burden, and disease severity, to determine the real-world impact of AI literacy on fibromyalgia management.</div></div><div><h3>Trial registration</h3><div>ClinicalTrials.gov Identifier: <span><span>NCT07020845</span><svg><path></path></svg></span>, Registration date: December 16, 2024.</div></div>","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"22 3","pages":"Article 502098"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147617309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rheumatic diseases in childhood: Clinical and immunological characteristics of a pediatric cohort at a tertiary hospital","authors":"Yedra Usón-Rodríguez ,&nbsp;Giuliano Boselli-Oporto ,&nbsp;Ignacio Ruiz del Olmo-Izuzquiza ,&nbsp;Julia Ulier-Bellmunt ,&nbsp;Marta Medrano-San Ildelfonso","doi":"10.1016/j.reumae.2026.502076","DOIUrl":"10.1016/j.reumae.2026.502076","url":null,"abstract":"<div><h3>Objective</h3><div>To describe the clinical, immunological, and healthcare characteristics of patients attended in a Pediatric Rheumatology unit of a tertiary Spanish hospital over ten years.</div></div><div><h3>Methods</h3><div>Retrospective observational study including all patients under 18 years evaluated between 2014 and 2024. Demographic data, diagnoses, immunological profile, presence of uveitis, treatments, and final healthcare status were collected.</div></div><div><h3>Results</h3><div>A total of 925 patients were evaluated; 59.8% were female. The most prevalent disease in the clinic was JIA (29.4%), with oligoarticular JIA being the most frequent subtype (49.2%), of whom 71.5% were positive for ANA and 17.7% had uveitis. Autoinflammatory diseases accounted for 10.2% and connective tissue diseases for 7.4%. At the time of analysis, 45.3% were still followed in paediatric care, and 9% were in transition to adult consultations.</div></div><div><h3>Conclusions</h3><div>Our case series is similar to that described in other Pediatric Rheumatology units in our region, highlighting the higher frequency of oligoarticular JIA and its association with positive ANA.</div></div>","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"22 3","pages":"Article 502076"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147489090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the SER/SEPAR criteria for the screening of interstitial lung disease in a large cohort of patients with rheumatoid arthritis","authors":"Javier Bachiller-Corral,&nbsp;Jesus Loarce-Martos,&nbsp;Verónica García-García,&nbsp;Sonia Jiménez Barrios,&nbsp;Alonso Gonzales Montes,&nbsp;Mauro Ferre-Sanfrancisco,&nbsp;María Auxiliadora Martin-Martínez,&nbsp;Mónica Vázquez-Díaz","doi":"10.1016/j.reumae.2026.502049","DOIUrl":"10.1016/j.reumae.2026.502049","url":null,"abstract":"<div><h3>Objective</h3><div>To validate, in routine clinical practice, the SER/SEPAR criteria for the screening of rheumatoid arthritis (RA)-associated interstitial lung disease (ILD).</div></div><div><h3>Methods</h3><div>A retrospective study was conducted in patients with RA who had undergone high-resolution computed tomography (HRCT) of the lungs within the past 5 years. Clinical and radiological variables were collected, and the proposed screening criteria were applied. Sensitivity and specificity of the overall algorithm, as well as of its individual components, were calculated.</div></div><div><h3>Results</h3><div>A total of 270 patients were included (71% women), with a mean age of 64.3 years and a mean disease duration of 10.8 years. Among them, 58 patients (21.5%) had ILD on HRCT. Application of the SER/SEPAR criteria yielded a sensitivity of 96.5% and a specificity of 25%, recommending screening tests in 90% of patients and HRCT in 75% of them. The individual sensitivity of chest radiography and pulmonary function tests (PFTs) for the detection of ILD was low (≤50%) in both symptomatic and asymptomatic patients. The presence of lung crackles on lung auscultation was the finding with the highest specificity (92.9%).</div></div><div><h3>Conclusion</h3><div>The SER/SEPAR screening criteria show excellent sensitivity but low specificity, leading to the recommendation of diagnostic testing in the majority of patients. In our cohort, chest X-ray and PFTs demonstrated limited utility for ILD screening in patients with RA.</div></div>","PeriodicalId":94193,"journal":{"name":"Reumatologia clinica","volume":"22 2","pages":"Article 502049"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}