La Revue de medecine interne最新文献

[Erdheim-Chester disease associated with Langerhans cell histiocytosis: A case of a mixed form].

La Revue de medecine interne Pub Date : 2025-04-03 DOI: 10.1016/j.revmed.2025.02.012

Houria Sahel, Billel Merrouche, Souad Bellaifa, Nacima Djennane, Zine Charef Amir, Abdelkrim Talbi, Ammar Maireche, Radhia Ait Chalal, Amine Habouchi

{"title":"[Erdheim-Chester disease associated with Langerhans cell histiocytosis: A case of a mixed form].","authors":"Houria Sahel, Billel Merrouche, Souad Bellaifa, Nacima Djennane, Zine Charef Amir, Abdelkrim Talbi, Ammar Maireche, Radhia Ait Chalal, Amine Habouchi","doi":"10.1016/j.revmed.2025.02.012","DOIUrl":"https://doi.org/10.1016/j.revmed.2025.02.012","url":null,"abstract":"Introduction: Langerhans cell histiocytosis and Erdheim-Chester disease are rare inflammatory myeloid neoplasms. They present characteristic clinical, histological and radiological signs. Their association is exceptional. We report a new observation.Observation: A 47-year-old man presented with lesions of seborrheic dermatitis-like, intracranial hypertension, paralysis of the sixth cranial nerve, and central diabetes insipidus. The skin biopsy concluded that there was Langerhans cell histiocytosis. The bone scan showed metaphyseal-diaphyseal osteosclerotic lesions of the femur, tibia and humerus. The thoraco-abdomino-pelvic CT scan showed an aortic sheathing, suggesting Erdheim-Chester disease. The search for the BRAFV600E mutation was negative. The patient was treated with oral corticosteroid therapy then with cladribine which allowed a good evolution.Conclusion: We report an observation of a mixed form of histiocytosis associating Langerhans cell histiocytosis and Erdheim-Chester disease, with a diagnostic delay of ten years, and having responded well to treatment with cladribine.","PeriodicalId":94122,"journal":{"name":"La Revue de medecine interne","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Giant cell arteritis revealed by bilateral internuclear ophthalmoplegia].

La Revue de medecine interne Pub Date : 2025-04-03 DOI: 10.1016/j.revmed.2025.02.013

Robin Deshayes, Jesus Aguilar, Géraldine Mineur, Romain Collot, Olivier Espitia, Christian Agard

引用次数: 0

[Monogenic autoinflammatory uveitis].

La Revue de medecine interne Pub Date : 2025-03-25 DOI: 10.1016/j.revmed.2025.03.001

Hippolyte Lequain, Laurent Kodjikian, Isabelle Meunier, Yvan Jamilloux, Pascal Sève

引用次数: 0

[Atrial fibrillation in 2025: Diagnosis and treatment].

La Revue de medecine interne Pub Date : 2025-03-12 DOI: 10.1016/j.revmed.2025.02.010

Jean-Marc Sellal, Néfissa Hammache, Mathieu Echivard

引用次数: 0

[Neurolymphomatosis].

La Revue de medecine interne Pub Date : 2025-03-10 DOI: 10.1016/j.revmed.2025.02.003

Fanny Urbain, Louise Bicart-See, Clovis Adam, David Adams, Olivier Lambotte, Céline Labeyrie, Nicolas Noel

{"title":"[Neurolymphomatosis].","authors":"Fanny Urbain, Louise Bicart-See, Clovis Adam, David Adams, Olivier Lambotte, Céline Labeyrie, Nicolas Noel","doi":"10.1016/j.revmed.2025.02.003","DOIUrl":"https://doi.org/10.1016/j.revmed.2025.02.003","url":null,"abstract":"Neurolymphomatoses (NL) are defined as the direct infiltration of the peripheral nervous system (PNS) by lymphomatous or leukaemic cells. The diagnosis of this rare disease is complex, typically relying on peripheral nerve histology, an invasive examination with a risk of sequelae. This diagnostic entity should be considered in the presence of a painful neuropathy, sometimes severe, whether or not associated with immunohaematological abnormalities, and in cases of resistance to first-line immunomodulatory treatments. NLs are classified into primary, which are limited to or originate from the peripheral nerve, and secondary NLs resulting from systemic involvement. The epineurium, the perineurium and the endoneurium might be affected. Diffuse large B-cell lymphomas are the most frequent histological entity, followed by marginal zone and lymphoplasmacytic lymphomas. The genesis of these infiltrations and their links with primary central nervous system lymphomas are not clearly established. In the future, the contribution of multimodal imaging techniques (whole-body PET, plexus MRI, nerve ultrasound) and sensitive technologies for detecting lymphoid clones (molecular biology, immunophenotyping) as well as therapeutic sequences will need to be clarified by dedicated multicentre studies.","PeriodicalId":94122,"journal":{"name":"La Revue de medecine interne","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Immuno'logical (the scientific updates you wouldn't dare to read anywhere else): X chromosome, Xist, and female autoimmunity].

La Revue de medecine interne Pub Date : 2025-03-07 DOI: 10.1016/j.revmed.2025.02.009

Valentin Lacombe

引用次数: 0

[Artificial intelligence in healthcare: A survival guide for internists].

La Revue de medecine interne Pub Date : 2025-02-20 DOI: 10.1016/j.revmed.2025.02.002

Thomas Barba, Marie Robert, Arnaud Hot

引用次数: 0

Vulnerability of hospitalized patients during community disease outbreaks: Lessons from the early COVID-19 pandemic.

La Revue de medecine interne Pub Date : 2025-02-07 DOI: 10.1016/j.revmed.2025.01.003

Eliana Wassermann, Claude Bachmeyer, Guillaume Lemaitre, Mélodie Bernaux, Christel Daniel, Judith Leblanc, Olivier Steichen

{"title":"Vulnerability of hospitalized patients during community disease outbreaks: Lessons from the early COVID-19 pandemic.","authors":"Eliana Wassermann, Claude Bachmeyer, Guillaume Lemaitre, Mélodie Bernaux, Christel Daniel, Judith Leblanc, Olivier Steichen","doi":"10.1016/j.revmed.2025.01.003","DOIUrl":"https://doi.org/10.1016/j.revmed.2025.01.003","url":null,"abstract":"Objectives: Hospital-acquired infections (HAIs) during community disease outbreaks threaten vulnerable hospitalized patients. This study compares the outcomes of hospitalized patients who had COVID-19 as either a HAI or a community-acquired infection (CAI).Methods: We conducted a retrospective cohort study involving adult patients hospitalized across 39 greater Paris University hospitals between January 27th, 2020, and April 21st, 2021, who tested positive for SARS-CoV-2 PCR during their stay. Patients were classified as CAI if they tested positive within 72hours of admission and HAI if they tested negative within 72hours but later positive. HAI was subclassified as possible (first positive test between days 4-7), probable (days 8-13), or definite (day 14 onward). Patients with probable or definite HAI were matched 1:3 to CAI patients for age, sex, and comorbidities, to compare intensive care unit (ICU) transfer and in-hospital death between both groups.Results: Of 10,831 patients, 506 (4.7%) were classified as HAI. They were older and had more comorbidities. After matching, the 333 patients with probable or definite HAI were less likely to be transferred to the ICU (hazard ratio [HR] 0.57, 95% CI 0.38-0.85) compared to their 999 CAI controls and had a higher risk for in-hospital death (HR 1.58, 95% CI 1.16-2.14).Conclusion: Patients with COVID-19 as a HAI face a higher risk of death compared to patients hospitalized with COVID-19 acquired in the community and are less likely to be admitted to the ICU. Strict infection control measures are needed during community outbreaks to protect hospitalized patients.","PeriodicalId":94122,"journal":{"name":"La Revue de medecine interne","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143375071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Ridged nails].

La Revue de medecine interne Pub Date : 2025-01-29 DOI: 10.1016/j.revmed.2025.01.005

S Vignes

引用次数: 0

[Screening for sleep disorders in internal medicine as potential comorbidities of systemic autoimmune diseases and improving patients' quality of life]. [筛选内科睡眠障碍作为系统性自身免疫性疾病的潜在合并症和改善患者的生活质量]。

La Revue de medecine interne Pub Date : 2024-11-27 DOI: 10.1016/j.revmed.2024.11.012

É Riviere, V Martin, P Philip, J Coelho, J-A Micoulaud-Franchi

引用次数: 0