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Heightened Revision Risk After Ankle Ligament Repair in Patients With Ehlers-Danlos Syndrome or Hypermobility Spectrum Disorder: A Propensity-Matched National Database Study. ehers - danlos综合征或多动谱系障碍患者踝关节韧带修复后翻修风险增加:一项倾向匹配的国家数据库研究
IF 2.2
Foot & ankle international Pub Date : 2025-09-15 DOI: 10.1177/10711007251363246
Peter V Dinh, Jacob M Johnson, Timothy A Reiad, David Bruni, Alexa Bosco, John Milner, Brett D Owens, Stephen Marcaccio, Alan H Daniels, Raymond Y Hsu
{"title":"Heightened Revision Risk After Ankle Ligament Repair in Patients With Ehlers-Danlos Syndrome or Hypermobility Spectrum Disorder: A Propensity-Matched National Database Study.","authors":"Peter V Dinh, Jacob M Johnson, Timothy A Reiad, David Bruni, Alexa Bosco, John Milner, Brett D Owens, Stephen Marcaccio, Alan H Daniels, Raymond Y Hsu","doi":"10.1177/10711007251363246","DOIUrl":"https://doi.org/10.1177/10711007251363246","url":null,"abstract":"<p><strong>Background: </strong>This study investigates revision surgery rates in patients with Ehlers-Danlos Syndrome (EDS) or hypermobility spectrum disorder (HSD) following ankle surgery for instability compared to matched controls.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted using the PearlDiver Mariner 170 Database. Patients undergoing ankle ligament repair procedures were identified using <i>Current Procedural Terminology</i> (<i>CPT</i>) codes. The experimental cohort included patients with EDS or HSD with at least 2 years of follow-up data, excluding other connective tissue disorders and confounding conditions. Propensity score matching was used to create a matched control group. The primary outcome was the rate of revision ankle ligament repair within 2 and 5 years. The secondary outcome was the effect of patient risk factors associated with revision. Revision rates were compared between cohorts using multivariable logistic regression. Statistical significance was set at <i>P</i> < .05.</p><p><strong>Results: </strong>The 2-year cohort included 805 patients with EDS/HSD and 805 matched controls, whereas the 5-year cohort consisted of 480 patients in each group. Procedures primarily involved modified Brostrom repair, lateral ankle ligament reconstruction, and arthroscopic-assisted repairs. Patients with EDS/HSD had significantly higher revision rates at 2 years (13.8% vs 6.3%) and 5 years (19.4% vs 7.3%) (<i>P</i> < .0001). Multivariate analysis identified EDS/HSD as an independent risk factor for revision surgery, with adjusted odds ratios of 2.41 (95% CI 1.71-3.45; <i>P</i> < .0001) at 2 years and 3.11 (95% CI 2.07-4.77; <i>P</i> < .0001) at 5 years.</p><p><strong>Conclusion: </strong>This study highlights the significant challenges in surgical management of ankle instability in patients with EDS and HSD. The risk of surgical failure increases over time, with a 3.1-fold increase in revision surgery rates at 5 years postoperatively compared with matched controls. These findings emphasize the need for specialized surgical approaches and comprehensive perioperative care to address the unique risks in this population. Future work should compare specific repair techniques and graft choices in this high-risk cohort.</p>","PeriodicalId":94011,"journal":{"name":"Foot & ankle international","volume":" ","pages":"10711007251363246"},"PeriodicalIF":2.2,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Deltoid Ligament Repair in Surgically Treated Weber C Ankle Fractures With Deltoid Injury: A Retrospective Comparative Study. Weber C型踝关节骨折合并三角肌损伤后三角韧带修复的回顾性比较研究。
IF 2.2
Foot & ankle international Pub Date : 2025-09-14 DOI: 10.1177/10711007251361122
Ahmed Khalil Attia, Torben H Urdahl, Carissa C Dock, Rebecca Stone McGaver, Bryan D Den Hartog, J Chris Coetzee, William M Engasser, Paul M Cammack, John C Tanner, Kayla J Seiffert, Jeffrey D Seybold
{"title":"Outcomes of Deltoid Ligament Repair in Surgically Treated Weber C Ankle Fractures With Deltoid Injury: A Retrospective Comparative Study.","authors":"Ahmed Khalil Attia, Torben H Urdahl, Carissa C Dock, Rebecca Stone McGaver, Bryan D Den Hartog, J Chris Coetzee, William M Engasser, Paul M Cammack, John C Tanner, Kayla J Seiffert, Jeffrey D Seybold","doi":"10.1177/10711007251361122","DOIUrl":"https://doi.org/10.1177/10711007251361122","url":null,"abstract":"<p><strong>Background: </strong>The indications for deltoid ligament (DL) repair in ankle fractures with widened medial clear space (MCS) remain controversial. Many authors report no difference in long-term functional outcomes, whereas others report persistent MCS widening and higher malreduction rates without DL repair. This study compares DL repair to no repair exclusively in surgically treated bimalleolar equivalent Weber C fibula fractures.</p><p><strong>Methods: </strong>This was a retrospective chart review of surgically treated Weber C lateral malleolus fractures with syndesmosis stabilization, with associated DL injury (bimalleolar equivalent). Patients with associated posterior or medial malleolus fractures, Weber B or A fractures, fibula fixation constructs other than plate and screws, follow-up less than 12 months, and revisions were excluded. Those meeting the inclusion criteria were split into 2 groups: DL repair vs no repair. Collected data included patient demographics, surgical procedures performed, and outcome measures. Primary outcomes measured postoperative oblique MCS and valgus talar tilt angle (TTA). Secondary outcomes included fracture union, complications, and patient-reported outcome measures (PROMs).</p><p><strong>Results: </strong>Seventy-seven fractures were included; 48 underwent DL repair whereas 29 did not. The mean follow-up was 28.9 months. Most study outcomes within each group had a statistically significant postoperative improvement. The valgus TTA in the repair vs no repair groups was 0.1 ± 0.9 vs 1.3 ± 2.0 degrees, respectively (<i>P</i> < .001). The MCS in the repair vs no repair groups was 3.5 ± 0.6 vs 3.8 ± 1.3 mm, respectively (<i>P</i> = .169). There were statistically significant differences in favor of DL repair in postoperative Veterans RAND-12 Item Health Survey physical subscale (<i>P</i> = .025) and Foot and Ankle Ability Measure activities of daily living subscale (<i>P</i> = .044) scores. There were no complications or revision surgeries directly related to DL repair.</p><p><strong>Conclusion: </strong>The DL repair group had superior functional outcomes and ankle coronal plane alignment in comparison to no repair. There were no complications or revisions related directly to the deltoid repair. These results support consideration of DL repair in bimalleolar equivalent Weber C ankle fractures to improve functional outcomes and coronal plane alignment.</p>","PeriodicalId":94011,"journal":{"name":"Foot & ankle international","volume":" ","pages":"10711007251361122"},"PeriodicalIF":2.2,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allograft Bone-Block Plantarflexion First Tarsometatarsal Arthrodesis: Short-term Outcomes. 同种异体骨块跖屈曲首次跗跖关节融合术:短期结果。
IF 2.2
Foot & ankle international Pub Date : 2025-09-12 DOI: 10.1177/10711007251363926
Nacime Salomao Barbachan Mansur, Aly Fayed, Rogerio Chinelati, Eli Schmidt, Matthieu Lalevee, Cesar de Cesar Netto
{"title":"Allograft Bone-Block Plantarflexion First Tarsometatarsal Arthrodesis: Short-term Outcomes.","authors":"Nacime Salomao Barbachan Mansur, Aly Fayed, Rogerio Chinelati, Eli Schmidt, Matthieu Lalevee, Cesar de Cesar Netto","doi":"10.1177/10711007251363926","DOIUrl":"https://doi.org/10.1177/10711007251363926","url":null,"abstract":"<p><strong>Background: </strong>Patients with progressive collapsing foot deformity (PCFD), hallux valgus (HV), and midfoot arthritis (MA) could benefit from a bone-block tarsometatarsal (TMT) arthrodesis. The allograft wedge, producing distraction and plantarflexion, provides a stable medial column while correcting the deformity, but with increased risk of pseudoarthrosis. The objective of this study was to report the clinical nonunion and results of the bone-block first-TMT arthrodesis in collapsed feet.</p><p><strong>Methods: </strong>In this short-term prospective cohort (mean follow-up 17 months) we evaluated patients with PCFD, HV, and MA who underwent allograft bone-block first-TMT fusion between August 2020 and November 2022. Patients were kept nonweightbearing for 6 weeks and followed, having a WBCT at 3 months and subsequent follow-ups. Bone healing was determined by at least 50% of bone trabeculae crossing both graft interfaces. Complications were documented. Forefoot arch angle (FAA), Meary angle, talonavicular coverage angle (TNCA), middle facet subluxation (MFS), and foot and ankle offset (FAO) were obtained, as well as PROs.</p><p><strong>Results: </strong>Sixty-four patients (67 feet) were included, mean age 54.0 (18-77), body mass index 31.6 (29.6-33.6), 17.3 months (6-33) follow-up. Median allograft size was 8 mm (5-19 mm). Clinical nonunion rate was 11.9%, minor complications 2.9%, and major complications 5.9%. Tomographic healing at 3 months occurred in 86.4% and 66.7% at the most recent WBCT (mean: 10.1 months; 6-29). Improvement (<i>P</i> < .001) in FAA of 6.9 degrees (5.8-7.9), MFS of 22.6% (19.8-25.4), TNCA of 13.5 (12.1-14.3), Meary angle of 8.1 degrees (6.7-9.5), and FAO of 3.8% (3.1-4.6) were found. PROs improved for VAS, PROMIS-PH, PROMIS-PI, Pain Catastrophic Scale, and EFAS (<i>P</i> < .001).</p><p><strong>Conclusion: </strong>Although the first-TMT bone-block arthrodesis restored many markers associated with foot collapse and alignment, the clinical nonunion rate was 11.9%, which is in the top range of the literature for TMT fusions. The use of allograft wedges can explain our findings. Tomographic healing, initially 86.4% at 3 months, decreased to 66.7% at the most recent follow-up.</p>","PeriodicalId":94011,"journal":{"name":"Foot & ankle international","volume":" ","pages":"10711007251363926"},"PeriodicalIF":2.2,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally Invasive vs Open Distal Metatarsal Osteotomy for Hallux Valgus: A Randomized Controlled Trial of Short-term Wound Healing and 1-Year Outcomes. 微创与开放式跖远端截骨治疗拇外翻:一项短期伤口愈合和1年预后的随机对照试验。
IF 2.2
Foot & ankle international Pub Date : 2025-09-11 DOI: 10.1177/10711007251361121
Mario I Escudero, Francisco Escobar, Carlos F Albarrán, Andrés Medina, Manuel J Pellegrini
{"title":"Minimally Invasive vs Open Distal Metatarsal Osteotomy for Hallux Valgus: A Randomized Controlled Trial of Short-term Wound Healing and 1-Year Outcomes.","authors":"Mario I Escudero, Francisco Escobar, Carlos F Albarrán, Andrés Medina, Manuel J Pellegrini","doi":"10.1177/10711007251361121","DOIUrl":"https://doi.org/10.1177/10711007251361121","url":null,"abstract":"<p><strong>Background: </strong>Hallux valgus (HV) often requires surgical intervention following the failure of conservative treatment. This study compared the minimally invasive transverse distal metatarsal osteotomy and percutaneous Akin (MITO) technique with open chevron Akin (OC) surgery over 1 year in patients with mild to moderate HV.</p><p><strong>Methods: </strong>In this prospective randomized controlled trial, 40 patients (40 feet) were randomized to receive MITO (20 feet) or OC (20 feet) between January 2019 and 2022. Follow-up was conducted at 6 weeks, 3 months, 6 months, and 1 year postsurgery, with evaluations including assessment of wound healing using the PWAT and ASEPSIS scores, patient-reported outcome measures (PROMs), AOFAS scale, and radiologic measures.</p><p><strong>Results: </strong>There were no notable differences in surgical time, PROMs, AOFAS scale, or radiologic results at the 1-year follow-up. The only significant difference observed was the PWAT score at the 6-week mark, favoring the MITO group. Overall, the complication rate stood at 15% for both groups, with no reports of significant complications.</p><p><strong>Conclusion: </strong>At the 6-week mark, the MITO technique demonstrated beneficial progress in postoperative soft tissue evolution. At the 1-year follow-up, both groups improved regarding radiologic outcomes. This study supports the short-term benefit of percutaneous techniques on early wound healing, while confirming similar 1-year functional and radiographic outcomes compared to open techniques.</p>","PeriodicalId":94011,"journal":{"name":"Foot & ankle international","volume":" ","pages":"10711007251361121"},"PeriodicalIF":2.2,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative GLP-1 Receptor Agonist Use and Postoperative Outcomes Following Operative Ankle Fracture Repair in Patients With Type 2 Diabetes: A National Database Study. 术前GLP-1受体激动剂的使用和2型糖尿病患者手术踝关节骨折修复术后的预后:一项国家数据库研究
IF 2.2
Foot & ankle international Pub Date : 2025-09-09 DOI: 10.1177/10711007251364187
Carter J K White, Ankit Choudhury, Harshavardhan Bollepalli, Jacob D Kodra, Alex T Burton, Jonathan C Kraus
{"title":"Preoperative GLP-1 Receptor Agonist Use and Postoperative Outcomes Following Operative Ankle Fracture Repair in Patients With Type 2 Diabetes: A National Database Study.","authors":"Carter J K White, Ankit Choudhury, Harshavardhan Bollepalli, Jacob D Kodra, Alex T Burton, Jonathan C Kraus","doi":"10.1177/10711007251364187","DOIUrl":"https://doi.org/10.1177/10711007251364187","url":null,"abstract":"<p><strong>Background: </strong>Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are increasingly used in management of type 2 diabetes mellitus (T2DM) and obesity. Beyond glycemic control, these agents may influence orthopaedic outcomes. This study aimed to assess the relationship between preoperative GLP-1 RA use and postoperative complications in T2DM patients undergoing operative ankle fracture repair.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted using the TriNetX database, identifying adult patients with T2DM who underwent operative ankle fracture repair from 2005 to 2024. Patients were stratified based on preoperative GLP-1 RA exposure within 180 days of surgery. Propensity score matching (1:1) was performed on demographics, medications, comorbidities, and laboratory values. Postoperative outcomes were analyzed in 3 domains: (1) medical complications within 90 days, (2) operative and implant-related complications from 90 to 180 days, and (3) health care utilization at 30, 90, and 180 days.</p><p><strong>Results: </strong>A total of 1,107 patients were analyzed in each group after matching. After false discovery rate correction, GLP‑1 RA use was associated only with lower all‑cause mortality (odds ratio [OR] 0.33, 95% CI 0.16-0.67, adjusted <i>P</i> = .011; number needed to treat = 56) and higher fall‑related injuries (OR 1.32, 95% CI 1.12-1.57, adjusted <i>P</i> = .011; number needed to harm = 15). No significant differences were observed in infection, posttraumatic arthritis, persistent opioid use, and wound healing complications.</p><p><strong>Conclusion: </strong>Preoperative GLP-1 RA use in T2DM patients undergoing operative ankle fracture repair may reduce postoperative all-cause mortality but increase fall-related injuries. These findings underscore a complex risk-benefit profile of GLP-1 RA therapy in orthopaedic care.</p>","PeriodicalId":94011,"journal":{"name":"Foot & ankle international","volume":" ","pages":"10711007251364187"},"PeriodicalIF":2.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Retrospective Cohort Study From 2 Academic Medical Centers: Oral vs Intravenous Antibiotics for Diabetic Osteomyelitis. 来自2个学术医学中心的回顾性队列研究:口服与静脉注射抗生素治疗糖尿病性骨髓炎。
IF 2.2
Foot & ankle international Pub Date : 2025-09-08 DOI: 10.1177/10711007251344583
Jennifer A Kipp, Lindsay K LeSavage, Joni K Evans, Julia C Tolin, Julianne Vesce, Travis Denmeade, Ricardo Arbulu, Jeffrey Manway, Cody D Blazek
{"title":"A Retrospective Cohort Study From 2 Academic Medical Centers: Oral vs Intravenous Antibiotics for Diabetic Osteomyelitis.","authors":"Jennifer A Kipp, Lindsay K LeSavage, Joni K Evans, Julia C Tolin, Julianne Vesce, Travis Denmeade, Ricardo Arbulu, Jeffrey Manway, Cody D Blazek","doi":"10.1177/10711007251344583","DOIUrl":"https://doi.org/10.1177/10711007251344583","url":null,"abstract":"<p><strong>Background: </strong>The Infectious Diseases Society of America guidelines recommend a prolonged course of antibiotics in the setting of residual osteomyelitis. More recently published literature suggests that oral antibiotics may offer comparable outcomes to intravenously administered antibiotics when treating orthopaedic infections. In a prior study, we investigated the outcomes of both routes of antibiotic administration in patients with diabetic foot infections at a single academic medical institution.</p><p><strong>Methods: </strong>The goal of this study is to retrospectively evaluate the therapeutic success in 196 patients receiving oral or intravenous antibiotics for treatment of residual infection following amputation at 2 academic medical centers. Treatment was considered successful if patients who completed a minimum of 4 weeks of antibiotic therapy had complete wound healing and did not require additional debridement or amputation within 1 year of their initial surgery.</p><p><strong>Results: </strong>After performing a retrospective chart review, no difference was determined in treatment success between patients who underwent oral or intravenous antibiotics at either WFBMC (<i>P</i> = .34) or UPMC (<i>P</i> = .99). No difference in success was found when combining institutional data (<i>P</i> = .52). The median time to healing for oral antibiotics was 3.21 months compared with 3.85 months for intravenous (<i>P</i> = .16). Reoperation rates did not differ among treatment types (<i>P</i> = .53). Hemoglobin A<sub>1c</sub> values were lower among patients with treatment success (8.6 ± 2.3) versus failure (9.5 ± 2.5) (<i>P</i> = .016).</p><p><strong>Conclusion: </strong>This study supports the consideration of oral antibiotics as a viable option for selected diabetic patients with residual osteomyelitis. No significant differences were observed in treatment success, healing time, or reoperation rates, although the study was not powered to determine equivalence.</p>","PeriodicalId":94011,"journal":{"name":"Foot & ankle international","volume":" ","pages":"10711007251344583"},"PeriodicalIF":2.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term Functional Outcomes After Operatively Treated Unimalleolar, Bimalleolar, and Trimalleolar Ankle Fractures: A 15-22-Year Follow-up Study of 125 Patients. 手术治疗单踝、双踝和三踝踝骨折后的长期功能结果:一项对125例患者15-22年的随访研究。
IF 2.2
Foot & ankle international Pub Date : 2025-09-08 DOI: 10.1177/10711007251361509
Anne Scheuer, Fabian T Spindler, Judith Schrempf, Wolfang Böcker, Hans Polzer, Sebastian F Baumbach
{"title":"Long-term Functional Outcomes After Operatively Treated Unimalleolar, Bimalleolar, and Trimalleolar Ankle Fractures: A 15-22-Year Follow-up Study of 125 Patients.","authors":"Anne Scheuer, Fabian T Spindler, Judith Schrempf, Wolfang Böcker, Hans Polzer, Sebastian F Baumbach","doi":"10.1177/10711007251361509","DOIUrl":"https://doi.org/10.1177/10711007251361509","url":null,"abstract":"<p><strong>Background: </strong>Despite considerable improvements in surgical treatment strategies for unstable ankle fractures, long-term follow-up studies on conventional treatment strategies are missing. The aim of the study was to assess the patient-reported long-term outcome (≥15 years) following surgically treated ankle fractures.</p><p><strong>Methods: </strong>Retrospective, single-center, outcome study with a current follow-up. Identified were all patients treated surgically for an unstable ankle fracture between January 2003 and October 2009. Treatment was performed according to the AO principles. General demographics, injury-, fracture- and treatment details, as well as the current patient-reported outcome (Olerud-Molander Ankle Score [OMAS], the Foot and Ankle Ability Measure [FAAM], the European Foot & Ankle Society Score [EFAS], and the EuroQoL-5 dimensions, 5 levels [EQ-5D-5L]) were assessed.</p><p><strong>Results: </strong>Of 398 eligible patients, 125 patients (31.4%; 54% female, 48% left side) were included. The average age at trauma was 43.1 ± 11.8 years, and the mean follow-up 17.8 ± 2.0 years. Overall, 43%, 22%, and 34% sustained a unimalleolar, bimalleolar, and trimalleolar fracture, respectively. In addition, 53% had a fracture to the posterior malleolus. The overall median outcome for the OMAS, FAAM daily, and EFAS daily were 100 (interquartile range [IQR] 15), 99 (IQR 7), and 96 (IQR 16), respectively. The EQ-5D-5L scored at a median of 1.00 (IQR 0.09). The number of malleoli fractured was the only factor affecting all outcome scores. A moderate or poor outcome was reported for 5% of unimalleolar, 18% of bimalleolar, and 30% of trimalleolar fractures.</p><p><strong>Conclusion: </strong>Although the overall functional outcome was good, about 15% of patients had considerable impairment. The only factor associated with the patient-reported outcomes was the number of malleoli fractured, with 30% of patients with a trimalleolar ankle fracture presenting inferior outcomes.</p>","PeriodicalId":94011,"journal":{"name":"Foot & ankle international","volume":" ","pages":"10711007251361509"},"PeriodicalIF":2.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Liposomal Bupivacaine in Ultrasound-Guided Peripheral Nerve Blocks for Postoperative Pain Management in Foot and Ankle Surgery. 布比卡因脂质体在超声引导下周围神经阻滞治疗足踝术后疼痛的疗效。
IF 2.2
Foot & ankle international Pub Date : 2025-09-08 DOI: 10.1177/10711007251359634
Jonathan McKeeman, Brendan Smith, Ajith Malige, Rebecca Bates, Anna Ng Pellegrino, James Lachman
{"title":"Efficacy of Liposomal Bupivacaine in Ultrasound-Guided Peripheral Nerve Blocks for Postoperative Pain Management in Foot and Ankle Surgery.","authors":"Jonathan McKeeman, Brendan Smith, Ajith Malige, Rebecca Bates, Anna Ng Pellegrino, James Lachman","doi":"10.1177/10711007251359634","DOIUrl":"https://doi.org/10.1177/10711007251359634","url":null,"abstract":"<p><strong>Background: </strong>In response to the opioid epidemic, many surgical specialties have adopted nonopioid pain management strategies. Ultrasound (US)-guided peripheral nerve blocks (PNBs) are effective in reducing pain and opioid consumption postsurgery. Liposomal bupivacaine (LB), shown effective in shoulder surgery, was approved in November 2023 for use in US-guided lower extremity blocks. This study compares the efficacy of LB in US-guided PNBs, surgeon-administered LB field blocks, and a control group using PNB with local anesthetic only.</p><p><strong>Methods: </strong>This prospective, randomized, single-anonymized controlled study enrolled patients undergoing elective foot and ankle surgery from March 2022 to January 2023. Patients were assigned to one of 3 groups: US-guided PNB with local anesthetic only, US-guided PNB with LB or local mix, or surgeon-administered LB or local mix field block. Postoperative opioid use, opioid requirements in oral morphine equivalents, block duration, and Patient-Reported Outcomes Measurement Information System (PROMIS) scores were tracked.</p><p><strong>Results: </strong>A total of 248 patients were included: 70 in the US-guided PNB with local anesthetic-only group, 98 in the US-guided PNB with LB group, and 80 in the surgeon-administered LB field block group. Patients in the US-guided LB group took fewer opioid pills between postoperative day (POD) 0 and POD 4 (median 4.0 pills vs. 6.5 and 5.5 pills in the other groups, <i>P</i> = .025). The US-guided LB group had a significantly longer block duration (<i>P</i> < .001). Postoperative opioid use was lower in the US-guided PNB with LB group, compared with the US-guided PNB with local anesthetic-only group and the surgeon-administered LB field block group (<i>P</i> < .001). One patient experienced temporary foot drop that resolved by POD 10.</p><p><strong>Conclusion: </strong>US-guided peripheral nerve blocks using liposomal bupivacaine were associated with reduced postoperative opioid consumption and prolonged block duration in patients undergoing foot and ankle surgery. Compared with both local anesthetic-only blocks and surgeon-administered field blocks with liposomal bupivacaine, US-guided delivery provided more sustained analgesia. These findings suggest a potential benefit of liposomal bupivacaine in regional anesthesia protocols, though further studies are warranted to assess its generalizability across surgical subtypes and to evaluate long-term safety.</p>","PeriodicalId":94011,"journal":{"name":"Foot & ankle international","volume":" ","pages":"10711007251359634"},"PeriodicalIF":2.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
No Time for Fatalism-Encouraging Long-Term Results After Talar Fracture Fixation. 距骨骨折固定后的远期疗效令人鼓舞。
IF 2.2
Foot & ankle international Pub Date : 2025-09-08 DOI: 10.1177/10711007251363932
Stefan Rammelt
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引用次数: 0
Embracing Change: Oral Antibiotics for Diabetic Foot Osteomyelitis. 拥抱改变:口服抗生素治疗糖尿病足骨髓炎。
IF 2.2
Foot & ankle international Pub Date : 2025-09-08 DOI: 10.1177/10711007251363254
Laura Certain
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引用次数: 0
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