Journal of gynecology, clinical obstetrics and reproductive medicine最新文献

{"title":"Drug Susceptibility Pattern and Associated Factors of Bacteria Isolated from Urinary Tract Infection among Pregnant Women Attending Antenatal Care in Teaching Referral Hospital, Southeast Ethiopia","authors":"","doi":"10.33140/jgrm.05.02.10","DOIUrl":"https://doi.org/10.33140/jgrm.05.02.10","url":null,"abstract":"Background: Urinary tract infection (UTI) is caused by bacteria from the digestive tract which climbs the opening of the urethra and begins to multiply to cause infection. UTI in pregnancy is associated with significant morbidity for both mother and baby. In most developing countries including Ethiopia, screening for UTI in pregnancy is not considered an essential part of Antenatal Care. This study aimed to assess the bacterial profile and antibiotic susceptibility pattern and associated risk factors among pregnant women in Madda Walabu University Goba Referral Hospital, Southeast Ethiopia. Methods: An institution-based cross-sectional study was conducted from June-August, 2020 . A total of 234 pregnant women were enrolled; data were collected using a structured questionnaire by a trained interviewer. Urine samples were collected from all pregnant women and culture on cysteine lysine electrolytes deficiency medium. Data were analyzed using SPSS 20.0. Descriptive statistics were used to explain the study participants with relevant variables. Logistic regression was used for data comparison. P-value <0.05 was accepted as statistically significant. Results: The overall prevalence of UTI was 23.9% among both asymptomatic and symptomatic groups. Of this screened midstream urine samples showed that 16% and 32.2%, had significant bacteriuria in the asymptomatic and symptomatic groups respectively. The prevalence of UTI was significantly associated with previous history of catheterization and urinary tract infection (p<0.05). E. coli was the most frequently isolated organism (42.9%) followed by coagulase-negative Staphylococcus (26.8%), and S. aureus (12.5%). Gram-negative and Gram-positive bacteria accounted for (59%) and (41%) respectively. Gram-negative isolates showed resistance to ampicillin, naldixic acid and trimethoprim/sulfamethoxazole. Also, all Gram-negative bacterial isolates revealed a high level of resistance against trimethoprim/sulfamethoxazole. Conclusion: Significant bacteriuria has been observed from both symptomatic and asymptomatic pregnant women. The majority of the isolates were resistant to commonly prescribed antibiotics. This calls for an early screening of all pregnant women for UTI and those found to be infected need treatment with an appropriate drug to avoid complications.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87076617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Uterine Rupture Of Healthy Uterus : About A Case And Literature Review","authors":"","doi":"10.33140/jgrm.05.02.09","DOIUrl":"https://doi.org/10.33140/jgrm.05.02.09","url":null,"abstract":"Uterine rupture in a healthy uterus remains a rare complication of labour. However, given its seriousness in putting the life of the mother and the fetus at risk, it is important to think about it in the presence of any metrorrhagia during labour, even in a healthy uterus. It is more frequent in the case of a scarred uterus. We present a rare case of spontaneous uterine rupture in a healthy uterus in a 28 year old patient with no previous history of pathological history, diagnosed after six hours of delivery due to postpartum haemorrhage. Through this case and the review of the literature, we discuss the extreme caution that must be maintained even in the case of a non-scarring uterus, as well as the clinical signs of appeal, the risk factors, the diagnostic methodology and the therapeutic management of this rare but potentially serious entity.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76059748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous and Successful Pregnancies After Premature Ovarian Insufficiency: Case Series","authors":"","doi":"10.33140/jgrm.05.01.13","DOIUrl":"https://doi.org/10.33140/jgrm.05.01.13","url":null,"abstract":"Premature ovarian insufficiency (POI) formerly referred to as premature menopause, premature ovarian failure or primary ovarian failure (POF) implies quantitative and qualitative alterations in the functional integrity of the ovarian follicles leading to irregularity of menses, clinical manifestations of signs and symptoms of menopause and impaired fertility performance. This phenomenon tends to occur in about 1% of the women population in their reproductive years and arbitrarily below the age of 40 years. We hereby present case series of seven subjects who were specifically complaining of infertility or low fertility from a total of 242 women with presumed diagnosis of premature ovarian insufficiency. These were extracted from a pool of 10,090 clients that were documented over a year’s period i.e. from January 1, 2020 up to December 31, 2020. Our patients achieved spontaneous pregnancies and underwent a normal course of the pregnancies that culminated in uneventful childbirths. The deliveries invariably took place in private setups. We maintained a close contact telemetrically and physically; and followed them up during their course of the delivery and the postpartum period since they were denoted as very high risk pregnancy. To the best of our knowledge, there is no isolated similar case report or publication in the Ethiopian setting. The objective of the case series presentation is linked with the intention of adding to the world literature highlighting its relevance, desire to create more awareness and establish the basis for further inspiration to develop future undertakings in the understanding of diminished ovarian reserve vis-a-vis premature ovarian insufficiency and spontaneous pregnancy.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76298068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Choosy Corona: Females are at an Advantage","authors":"","doi":"10.33140/jgrm.05.003","DOIUrl":"https://doi.org/10.33140/jgrm.05.003","url":null,"abstract":"Tiny Corona has no brain but still it is very choosy, it does not infect equally to all the human population. It infects more men than women more older population than younger one. There are reasons for that. Men are on the priority list because of certain reasons; if they are bald more venerable. However, the subjects who are carrying blood group ‘O’ they can be spared. Bald man with blood group ’A’ is worst hit. It is not yet certain but data show that sex steroid hormones and X chromosome products are able to keep this virus away besides immunity, life style, environment and genetic reasons. Strong immunity can certainly fight with this virus as it does for all infections.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81317829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Placenta-A Temporary, Multifunctional Organ Does Wonders for The Embryo","authors":"","doi":"10.33140/jgrm.05.01.09","DOIUrl":"https://doi.org/10.33140/jgrm.05.01.09","url":null,"abstract":"Placenta is all in all for the growing foetus; more so it also helps pregnant mothers during pregnancy in many ways, however, the most poorly researched organ. Generally, placentas are discarded after the deliveries but recent findings have shown that even it is useful after deliveries too. Histologically, it has very simple structure, its trophoblast is in a sense unique with response to osmotic shock and thermal stress. Mutation in DNA of mitochondrial trophoblasts can even change the metabolism of newborns. The time line of the placenta is too short (about 40 weeks) but performs and serves as many organs. Recent researches posed unexplainable results for antibody transport. Emerging evidence put placenta as a window to the developing brain.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80007655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary Tract Infection, Drug Resistance Profile And Fetal Outcomes Among Pregnant Women In Selected Health Facilites Of Addis Ababa, Ethiopia: A CrossSectional Study Design","authors":"","doi":"10.33140/jgrm.05.01.11","DOIUrl":"https://doi.org/10.33140/jgrm.05.01.11","url":null,"abstract":"Background: Urinary tract infection (UTI) is a commonly encountered health problem among pregnant women. Untreated UTI may result in fetal complications like preterm birth, low birth weight, intra uterine growth retardation and intrauterine fetal death. One of the major problems with bacterial pathogens is their ability to develop drug resistance. Determining drug susceptibility pattern of bacteria from urinary tract helps to identify effective drugs and minimize further adverse perinatal outcomes. The purpose of this study was to describe the magnitude and drug resistance profile of pregnant women and related fetal outcomes. Methods:A cross-sectional study was conducted from March to June 2019. Socio-demographic data of the study participants was collected by administering structured questionnaire after obtaining full consent of the participants. Clean catch mid-stream urine was collected from the study participants and the samples were transported to the laboratory with screw-capped container. Blood and MacConkey agar were used to cultivate bacteria from urine sample. Bacterial colonies were isolated and identified using standard biochemical properties. Antibacterial susceptibility test was done on Muller-Hinton agar using antibiotic discs. At the time of delivery, infant’s birth weight and gestational age was recorded on the log book as part of the daily work. Fetal outcome data were recorded from the log book and entered to EPI data management software then transferred to SPSS for analysis. Results:Out of 424 urine samples processed, 63 (14.9%) yielded significant bacteriuria. Fifty-nine out of 63 (93.7%) cases of UTIs were recorded among age group of 15-34 years. Escherichia coli, Klebsiellapneumoniae, and Staphylococcus aureus were the three dominant bacterial isolates. Most of the gram negative bacterial isolates were resistant to ampicillin and ceftazidime (43.2% each) while gram positive was resistant for tetracycline (36.8%). The result of this study showed that UTI had statistical association with the occurrence of Intrauterine Fetal Death (IUFD) and Prerupture of Membrane (PROM) (P<.05). Conclusion: Adverse fetal outcomes are significantly linked with the presence of UTI during pregnancy. The condition can be managed if early diagnosis and treatments are made for the mother","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74526658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Comorbidity and Impact On Survival in Women with Lung, Breast and Cervical Cancer","authors":"","doi":"10.33140/jgrm.05.01.12","DOIUrl":"https://doi.org/10.33140/jgrm.05.01.12","url":null,"abstract":"Background: The relationship between cancer incidence and mortality, and the resulting comorbidities of the elderly reflects current demographics trends Objective: The study aimed to investigate the prevalence of comorbidities and their impact on survival of women diagnosed with: NSCLC, breast and cervical cancer, at the National Institute of Oncology and Radiobiology in Havana, Cuba. Methods: Data were collected retrospectively from patients' clinical charts. The study involved 138 NSCLC, 1 598 breast cancer and 631 cervical cancer registered during 2007-2011. Comorbidity was classified according to the ICD-10 diagnosis code and was measured using Charlson Comorbidity Index. Associations between comorbidities and mortality by all causes were analyzed in Cox regression models. Results: The highest prevalence of comorbidities was in NSCLC (68.8%). The 3-year OS for NSCLC were 44.5% (95%CI: 29.3–59.7) and 23.3% (95%CI: 13.2–33.4) in patients without and with comorbidity, respectively (p=.01). The 5-year OS for breast cancer in the no comorbidity group was 91.4% (95%CI: 89.6–91.6) compared with 37.2% (95%CI: 32.7-59.9) in the comorbodity group (p=.00). The 5-year OS for cervical cancer in patients without diseases was (55.8% [95%CI: 50.7 – 59.9]), in women with comorbidity (27.7% [95%CI: 15.9–29.5]) (p =.00). Comorbidity was an independent predictor for overall survival: NSCL (HR Adjusted: 2.28 [95%CI: 1.43 - 3.65], p=.000), breast cancer (HR Adjusted: 3.16 [95%CI: 2.69–3.71], p=.000), cervical cancer (HR Adjusted: 1.38 [95%CI: 1.10–1.86], p=.032) Conclusions: Comorbidity is an important prognostic factor for women diagnosed with lung, breast and cervical cancer","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77498705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 and Preeclampsia","authors":"","doi":"10.33140/jgrm.05.004","DOIUrl":"https://doi.org/10.33140/jgrm.05.004","url":null,"abstract":"COVID-19 is RNA virus with many systemic effects, including hypertension. Preeclampsia leads to maternal and fetal morbidity and mortality. In addition, Preeclampsia and COVID -19 aggravate the risk of ICU admission and maternal death.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73509270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Removal of Dermoid Cyst Increase Expression of AMH?","authors":"L. Shingshetty, C. Fitzgerald","doi":"10.33140/jgrm.05.01.10","DOIUrl":"https://doi.org/10.33140/jgrm.05.01.10","url":null,"abstract":"Dermoid cysts are the most common form of all the ovarian teratomas and are usually benign in nature. They are also known as mature cystic teratoma.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89446129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report","authors":"N. Tounsi, I. Zemni, Fatma Saadalah, M. Slimane, N. Boujelbéne, M. Ayadi, Chargui Rhiad, R. Khaled","doi":"10.21613/GORM.2021.1191","DOIUrl":"https://doi.org/10.21613/GORM.2021.1191","url":null,"abstract":"Patients with advanced endometrial cancer had generally a poor prognostic with a median survival often less than one year. Isolated bone metastases as the first sign of the disease of endometrial cancer was a very exceptional situation rarely described in the literature. The goal of this report is to describe the management of this rare site of metastases and to reviewed Clinic pathological features and prognosis of isolated bone metastases. We present a case of a 56-year-old woman treated for endometrial cancer with isolated ribs bone metastases. She was complaining about progressive right rib pain as a first sign of the disease of endometrial cancer. She had a biopsy of the lesion in the last right thoracic rib. This has proved a metastatic adenocarcinoma compatible with an endometrial primary cancer. An endometrial biopsy showed moderately differentiated endometrioid adenocarcinoma. Imagery did not reveal any other sites of metastatic disease. The patient underwent bilateral salpingo-oophorectomy and hysterectomy, peritoneal washing, omentectomy, bilateral pelvic and par aortic lymphadenectomy. In addition, a right thoracotomy was carried out and complete surgical excision of the rib mass was successfully performed. Adjuvant chemotherapy was administrated. The patient is clinically free of disease 10 months following diagnosis. Single-bone extrauterine metastatic site and local disease limited to the uterus had better survival outcomes than Stage IVb endometrial cancer with multiple metastatic sites. Therefore, the patient treated with surgery with a clear margin continued to behave as early-stage endometrial cancer.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75635171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}