Journal of dental applications最新文献

Periodontal Treatment Reduces Circulating Pro-Inflammatory Cytokine and Chemokine Levels in African American HIV+ Individuals with Virological Suppression. 牙周治疗可降低病毒抑制的非裔美国艾滋病病毒感染者的循环促炎细胞因子和趋化因子水平。

Journal of dental applications Pub Date : 2022-01-01 Epub Date: 2022-08-10

C Sampath, E P Harris, V Berthaud, M A Tabatabai, D M Wilus, M A Crayton, K Moss, J Webster-Cyriaque, J H Southerland, J R Koethe, P R Gangula

{"title":"Periodontal Treatment Reduces Circulating Pro-Inflammatory Cytokine and Chemokine Levels in African American HIV+ Individuals with Virological Suppression.","authors":"C Sampath, E P Harris, V Berthaud, M A Tabatabai, D M Wilus, M A Crayton, K Moss, J Webster-Cyriaque, J H Southerland, J R Koethe, P R Gangula","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Periodontal Disease (PD), a chronic inflammatory disease, is highly prevalent among Persons Living With HIV (PLWH) and is characterized by microbial symbiosis and oxidative stress. Our hypothesis stipulates that periodontal therapy attenuates systemic inflammatory and bacterial burden while improving periodontal status in PLWH.Methods: Sixteen African Americans (AA) with suppressed HIV viremia on long-term Antiretroviral Therapy (ART) were recruited to this study. Participants were placed into two groups, based on their dental care status: group 1 (In-Care, IC) and group 2 (Out of Care, OC). Periodontal health was investigated at baseline, 3 months, 6 months, and 12 months. Cytokine/chemokines, microbial phyla, and Asymmetric Dimethylarginine (ADMA, a marker for endothelial cell dysfunction) levels were assessed in the serum. Statistical comparisons between groups and at different visits were performed using multiple comparison tests.Results: Across longitudinal visits, periodontal treatment significantly reduced the levels of several cytokines and chemokines. At baseline, the out of care group had significantly higher blood levels of ADMA and actinobacteria than the IC group. Periodontal treatment significantly altered the abundance of circulating genomic bacterial DNA for various phyla in out of care group.Conclusions: Periodontal treatment interventions effectively attenuated circulating pro-inflammatory cytokines and altered microbial translocation, both critical drivers of systemic inflammation in PLWH.","PeriodicalId":93776,"journal":{"name":"Journal of dental applications","volume":"8 1","pages":"477-487"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583701/pdf/nihms-1833397.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40653474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Ultrasonic Instrumentation on Finish Line Integrity 超声波仪器对终点线完整性的影响

Journal of dental applications Pub Date : 2021-10-29 DOI: 10.26420/jdentapp.2021.1114

S. I., Sharon E, Hendler A, B. G, Beytha N

{"title":"The Effect of Ultrasonic Instrumentation on Finish Line Integrity","authors":"S. I., Sharon E, Hendler A, B. G, Beytha N","doi":"10.26420/jdentapp.2021.1114","DOIUrl":"https://doi.org/10.26420/jdentapp.2021.1114","url":null,"abstract":"Purpose: Ultrasonic scaler is frequently used for temporary cement remnants removal from abutment teeth. A major concern is the alteration of the structural integrity of the abutment finishing line by the ultrasonic scaler. The current study evaluates the influence of ultrasonic scaling on the integrity of the finish line. The effect of finish line design (chamfer or feather edge), and its location (dentin or enamel) was also evaluated. Methods: Intact 22 human extracted molars were divided into 2 groups: finish line was prepared on enamel (n=11) and dentin (n=11), and further subdivided to finish line configuration groups (chamfer or knife-edge). Preparation of finish line was preformed following a standard repetitive procedure. 3D scans of the same tooth before and after ultrasonic instrumentation were performed. Pre and post scaling images were superimposed. The finish line alterations were evaluated and measured. The significance of the differences was evaluated using Students’ t-test. Results: The average alteration at the finish line area following ultrasonic scaling was 71.5 ± 24.6 μm. Higher alterations were found for enamel and for chamfer finish lines compared to dentin and knife edge, 134.4 ± 61.4 μm and 30.3 ±11.7 μm respectively. The highest change (228.6μm) was found for chamfer finish line located on enamel. The differences between groups were statistically significant (p<0.05). Conclusion: Ultrasonic scaling alters the topography of the finish line area of abutment teeth and thus may compromise marginal fit and integrity of the final restoration.","PeriodicalId":93776,"journal":{"name":"Journal of dental applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46028922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guided Periodontal Surgery: Digital Workflow for Correction of a Gingival Smile 引导牙周手术:矫正牙龈微笑的数字化工作流程

Journal of dental applications Pub Date : 2021-07-13 DOI: 10.26420/jdentapp.2021.1113

J. Mezzadri, Faculty Herrero Álvaro Andrade Curitiba Paraná Brazil Graduation Program, K. Silva, Moraes Gf, Manfron Apt

引用次数: 0

Importance of In Vitro Microenvironment on Differentiation and Translational Applications of Dental Pulp Stem Cells 体外微环境对牙髓干细胞分化及转化应用的重要性

Journal of dental applications Pub Date : 2021-06-26 DOI: 10.26420/jdentapp.2021.1112

Li Q

引用次数: 0

Two-Dimensional Intra-Oral Radiographs Compared to Three-Dimensional CBCT at Six-Month Post-Operative Evaluation of Secondary Bone-Grafting in Patients with Cleft Lip and Palate 二维口内x线片与三维CBCT在唇腭裂患者二次植骨术后6个月的比较

Journal of dental applications Pub Date : 2021-05-29 DOI: 10.26420/jdentapp.2021.1111

P WiedelA, H. Svensson, K. Hellén-Halme, H. Ghaffari, M. Becker, Oral

{"title":"Two-Dimensional Intra-Oral Radiographs Compared to Three-Dimensional CBCT at Six-Month Post-Operative Evaluation of Secondary Bone-Grafting in Patients with Cleft Lip and Palate","authors":"P WiedelA, H. Svensson, K. Hellén-Halme, H. Ghaffari, M. Becker, Oral","doi":"10.26420/jdentapp.2021.1111","DOIUrl":"https://doi.org/10.26420/jdentapp.2021.1111","url":null,"abstract":"Background: The aim of this study was to investigate whether a complementary Cone-Beam Computed Tomography (CBCT) in patients with Cleft Lip and Palate (CLP) after alveolar bone-grafting to clefts gave substantial additional information, and particularly whether such new information had any implications for the further care of the patients. Methods: Seventeen children, with complete CLP, 10 unilateral and seven bilateral clefts, in all 24 clefts, were evaluated six months after secondary alveolar bone-grafting with two-dimensional intra-oral radiographs complemented with CBCT. The mean age at bone-grafting was 8.8 years. Three different examiners evaluated the radiographic documentation. Results: The mean pre-operative cleft width was 5.8mm. In 15 of the 24 clefts the same interpretation was made on both two-dimensional radiographs and CBCT. In the remaining nine clefts, CBCT added important information to the treatment decision. Conclusions: For the evaluation six months post-operatively of the success of alveolar bone-grafting to clefts, the two-dimensional radiograph should be complemented with CBCT unless the two-dimensional radiograph without doubt reveals open residual cleft and clinical findings indicate graft failure.","PeriodicalId":93776,"journal":{"name":"Journal of dental applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45218363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Body Composition of Women Undergoing ART, and Its Relationship with Sex Hormones and Biochemical Indicators 接受抗逆转录病毒治疗的女性身体组成及其与性激素和生化指标的关系

Journal of dental applications Pub Date : 1900-01-01 DOI: 10.26420/jdentapp.2021.1110

S. Z, J. X, C. L

{"title":"The Body Composition of Women Undergoing ART, and Its Relationship with Sex Hormones and Biochemical Indicators","authors":"S. Z, J. X, C. L","doi":"10.26420/jdentapp.2021.1110","DOIUrl":"https://doi.org/10.26420/jdentapp.2021.1110","url":null,"abstract":"This study displays a retrospective cohort analysis in the Reproductive and Genetic Health Center of Peking University First Hospital. Data were collected from 411 women receiving ART. The body composition, sex hormones and biochemical indicators were assessed by Bioelectrical Impedance Analysis (BIA). Subjects were grouped by Body Mass Index (BMI) and Body Fat Percentage (BFP), and differences of body composition among groups were analyzed. Multiple linear regression analysis was used to evaluate the relationship between sex hormones, biochemical indicators and body composition. Compared with the non-overweight group (BMI <24kg/m²), the lean body mass and fat mass of the overweight group (BMI ≥24kg/m²) increased significantly (P <0.001). Notably, 43.7% of non-overweight subjects have increased body fat as distinguished by PBF. The visceral adipose tissue increased by 50.9% in subjects with more fat. Fasting Blood Glucose (FBG), triglyceride, Low Density Lipoprotein Cholesterol (LDL-C) and testosterone were positively correlated with trunk fat, while High Density Lipoprotein Cholesterol (HDL-C) and estradiol were negatively correlated with trunk fat. Moreover, total cholesterol was positively correlated with Bone Mineral Content (BMC). Therefore, this research demonstrated significant differences in body composition between overweight and non-overweight women receiving ART. Combining PBF with BMI, obesity can be identified more accurately. Biochemical metabolism and sex hormones were related to body composition. Therefore, women receiving ART require detailed measurements of body composition, not BMI. Further studies are needed to confirm the relationship between pregnancy outcomes and body composition in women receiving ART treatment.","PeriodicalId":93776,"journal":{"name":"Journal of dental applications","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69278621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0