Frontiers in sensors最新文献

Editorial: Thought leaders in sensor research: volume 1 社论：传感器研究领域的思想领袖：第 1 卷

Frontiers in sensors Pub Date : 2024-07-10 DOI: 10.3389/fsens.2024.1436661

Dermot Diamond

引用次数: 0

Electronic tongue made of gelatin self-supporting films on printed electrodes to detect lactose 用印刷电极上的明胶自支撑薄膜制成的电子舌检测乳糖

Frontiers in sensors Pub Date : 2024-06-04 DOI: 10.3389/fsens.2024.1401077

Ana C. V. Piccinin, Andrey Coatrini-Soares, Giuliana T. Franco, T. J. Bondancia, Juliana Coatrini-Soares, Osvaldo N. Oliveira, L. H. Mattoso

{"title":"Electronic tongue made of gelatin self-supporting films on printed electrodes to detect lactose","authors":"Ana C. V. Piccinin, Andrey Coatrini-Soares, Giuliana T. Franco, T. J. Bondancia, Juliana Coatrini-Soares, Osvaldo N. Oliveira, L. H. Mattoso","doi":"10.3389/fsens.2024.1401077","DOIUrl":"https://doi.org/10.3389/fsens.2024.1401077","url":null,"abstract":"An electronic tongue was developed for the detection of lactose content in commercial foods. This was accomplished by employing optimized detection units comprised of gelatin films and information visualization methods for data analysis. The films incorporating gelatin, tannic acid, and zein, served as the basis for the sensors, whose electrodes were screen printed using carbon black ink. Self-supporting films were produced using various combinations of these materials, some of which had limited solubility in water (from 33% to 36%). They were hydrophobic and yielded reproducible electrical impedance spectra to be used as sensing units. Lactose detection experiments were conducted using various standard concentrations and commercial food samples. Capacitance decreased with lactose concentration at low frequencies, with films lacking a hydrophobic coating showing higher capacitance signals (exceeding 200 nF). Low limits of detection were obtained for the most sensitive films, as low as 2.03 × 10−19 mol/L, comparable to existing biosensors to detect lactose. Combining data from four sensing units in an electronic tongue allowed for the differentiation of lactose concentrations ranging from 1 × 10−20 mol/L to 1 × 10−6 mol/L using the interactive document mapping (IDMAP) projection technique, leading to a silhouette coefficient of 0.716. The discriminatory power of the electronic tongue was validated by distinguishing between lactose-containing and lactose-free food products. These findings highlight the potential of electronic tongues made with sustainable materials for applications in food quality assessment and lactose intolerance management.","PeriodicalId":93754,"journal":{"name":"Frontiers in sensors","volume":"2 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141267941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Learning control for body caudal undulation with soft sensory feedback 利用软感觉反馈学习控制身体尾部起伏

Frontiers in sensors Pub Date : 2024-04-24 DOI: 10.3389/fsens.2024.1367992

Fabian Schwab, Mohamed El Arayshi, Seyedreza Rezaei, Hadrien Sprumont, Federico Allione, Claudio Mucignat, Ivan Lunati, C. M. Verrelli, A. Jusufi

{"title":"Learning control for body caudal undulation with soft sensory feedback","authors":"Fabian Schwab, Mohamed El Arayshi, Seyedreza Rezaei, Hadrien Sprumont, Federico Allione, Claudio Mucignat, Ivan Lunati, C. M. Verrelli, A. Jusufi","doi":"10.3389/fsens.2024.1367992","DOIUrl":"https://doi.org/10.3389/fsens.2024.1367992","url":null,"abstract":"Soft bio-mimetic robotics is a growing field of research that seeks to close the gap with animal robustness and adaptability where conventional robots fall short. The embedding of sensors with the capability to discriminate between different body deformation modes is a key technological challenge in soft robotics to enhance robot control–a difficult task for this type of systems with high degrees of freedom. The recently conceived Linear Repetitive Learning Estimation Scheme (LRLES)–to be included in the traditional Proportional–integral–derivative (PID) control–is proposed here as a way to compensate for uncertain dynamics on a soft swimming robot, which is actuated with soft pneumatic actuators and equipped with soft sensors providing proprioceptive information pertaining to lateral body caudal bending akin to a goniometer. The proposed controller is derived in detail and experimentally validated, with the experiment consisting of tracking a desired trajectory for the bending angle envelope while continuously oscillating with a constant frequency. The results are compared vis a vis those achieved with the traditional PID controller, finding that the PID endowed with the LRLES outperforms the PID controller (though the latter has been separately tuned) and experimentally validating the novel controller’s effectiveness, accuracy, and matching speed.","PeriodicalId":93754,"journal":{"name":"Frontiers in sensors","volume":"5 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140663766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum: AI-boosted CRISPR-Cas13a and total internal reflection fluorescence microscopy system for SARS-CoV-2 detection 勘误：用于检测 SARS-CoV-2 的 AI 增强 CRISPR-Cas13a 和全内反射荧光显微镜系统

Frontiers in sensors Pub Date : 2024-04-04 DOI: 10.3389/fsens.2024.1410989

引用次数: 0

Evaluation of a point-of-use device used for autoantibody analysis and its potential for following microcystin leucine-arginine exposure 评估用于自身抗体分析的使用点装置及其在微囊藻毒素亮氨酸暴露后的应用潜力

Frontiers in sensors Pub Date : 2024-02-09 DOI: 10.3389/fsens.2024.1302520

Hui Ma, Christine Loscher, Anne Parle-McDermott, Jenny Fitzgerald, Julie P. Meneely, Christopher Elliott, Richard Welten, G. Mchau, Edna Makule, Revocatus Lazaro Machunda, Yun Yun Gong, Martin Kimanya, Aoife S Crawley, Ivan Maguire, C. Murphy, Richard O’Kennedy

{"title":"Evaluation of a point-of-use device used for autoantibody analysis and its potential for following microcystin leucine-arginine exposure","authors":"Hui Ma, Christine Loscher, Anne Parle-McDermott, Jenny Fitzgerald, Julie P. Meneely, Christopher Elliott, Richard Welten, G. Mchau, Edna Makule, Revocatus Lazaro Machunda, Yun Yun Gong, Martin Kimanya, Aoife S Crawley, Ivan Maguire, C. Murphy, Richard O’Kennedy","doi":"10.3389/fsens.2024.1302520","DOIUrl":"https://doi.org/10.3389/fsens.2024.1302520","url":null,"abstract":"Introduction: Globally, the need for measuring exposure to algal toxins has become urgent due to ever-increasing reports of contamination in sea and freshwater, in shellfish and fish stocks and in aerosols.Methods: To address this issue, we evaluated the potential of determining autoantibodies to a panel of biomarkers known to be elevated following exposure to the hepatotoxin microcystin leucine-arginine. The presence of autoantibodies, specific to four selected stress-response, metabolomic and chaperone biomarkers, namely, Heat shock protein 1, Triosephosphate isomerase, Peroxiredoxin 1 and Peroxiredoxin 2 was employed in screening 371 serum samples from microcystin-exposed individuals in Tanzania. In addition, the capacity of the LightDeck fluorescence-based detector, a point-of-use device, to monitor these autoantibody responses in comparison to enzyme-linked immunosorbent assay was evaluated.Results: By using the determination of autoantibodies to this novel panel of biomarkers an altered response was observed following microcystin exposure, with levels generally upregulated. The presence of elevated levels of microcystin leucine-arginine in water, as well as in food sources in Tanzania, may potentially have significant health effects on the population.Discussion: This novel biomarker panel may have potential for the detection of microcystin leucine-arginine exposure as well as various microcystin exposure-associated cancers (e.g., hepatocellular cancer and colorectal cancer). In addition, the utilisation of the LightDeck point-of-use device proved successful for the rapid analysis of this biomarker panel.","PeriodicalId":93754,"journal":{"name":"Frontiers in sensors","volume":"120 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139849696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of a point-of-use device used for autoantibody analysis and its potential for following microcystin leucine-arginine exposure 评估用于自身抗体分析的使用点装置及其在微囊藻毒素亮氨酸暴露后的应用潜力

Frontiers in sensors Pub Date : 2024-02-09 DOI: 10.3389/fsens.2024.1302520

Hui Ma, Christine Loscher, Anne Parle-McDermott, Jenny Fitzgerald, Julie P. Meneely, Christopher Elliott, Richard Welten, G. Mchau, Edna Makule, Revocatus Lazaro Machunda, Yun Yun Gong, Martin Kimanya, Aoife S Crawley, Ivan Maguire, C. Murphy, Richard O’Kennedy

{"title":"Evaluation of a point-of-use device used for autoantibody analysis and its potential for following microcystin leucine-arginine exposure","authors":"Hui Ma, Christine Loscher, Anne Parle-McDermott, Jenny Fitzgerald, Julie P. Meneely, Christopher Elliott, Richard Welten, G. Mchau, Edna Makule, Revocatus Lazaro Machunda, Yun Yun Gong, Martin Kimanya, Aoife S Crawley, Ivan Maguire, C. Murphy, Richard O’Kennedy","doi":"10.3389/fsens.2024.1302520","DOIUrl":"https://doi.org/10.3389/fsens.2024.1302520","url":null,"abstract":"Introduction: Globally, the need for measuring exposure to algal toxins has become urgent due to ever-increasing reports of contamination in sea and freshwater, in shellfish and fish stocks and in aerosols.Methods: To address this issue, we evaluated the potential of determining autoantibodies to a panel of biomarkers known to be elevated following exposure to the hepatotoxin microcystin leucine-arginine. The presence of autoantibodies, specific to four selected stress-response, metabolomic and chaperone biomarkers, namely, Heat shock protein 1, Triosephosphate isomerase, Peroxiredoxin 1 and Peroxiredoxin 2 was employed in screening 371 serum samples from microcystin-exposed individuals in Tanzania. In addition, the capacity of the LightDeck fluorescence-based detector, a point-of-use device, to monitor these autoantibody responses in comparison to enzyme-linked immunosorbent assay was evaluated.Results: By using the determination of autoantibodies to this novel panel of biomarkers an altered response was observed following microcystin exposure, with levels generally upregulated. The presence of elevated levels of microcystin leucine-arginine in water, as well as in food sources in Tanzania, may potentially have significant health effects on the population.Discussion: This novel biomarker panel may have potential for the detection of microcystin leucine-arginine exposure as well as various microcystin exposure-associated cancers (e.g., hepatocellular cancer and colorectal cancer). In addition, the utilisation of the LightDeck point-of-use device proved successful for the rapid analysis of this biomarker panel.","PeriodicalId":93754,"journal":{"name":"Frontiers in sensors","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139789978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Talbot-Lau devices: a reappraisal 塔尔博特-劳装置：重新评估

Frontiers in sensors Pub Date : 2024-01-25 DOI: 10.3389/fsens.2023.1328490

C. M. Gómez-Sarabia, Jorge Ojeda-Castañeda

引用次数: 0

Promoting quality in low-cost gas sensor devices for real-world applications 提高实际应用中低成本气体传感器设备的质量

Frontiers in sensors Pub Date : 2023-12-18 DOI: 10.3389/fsens.2023.1317533

W. Reimringer, Christian Bur

{"title":"Promoting quality in low-cost gas sensor devices for real-world applications","authors":"W. Reimringer, Christian Bur","doi":"10.3389/fsens.2023.1317533","DOIUrl":"https://doi.org/10.3389/fsens.2023.1317533","url":null,"abstract":"Recent advancements in metal oxide semiconductor sensors enable system integrators to make sensor devices without the traditional complications of operating barebone sensor components. Anyone, so it seems, can put together multi-sensor-systems by combining an integrated sensor subsystem with a small piece of digital infrastructure, resulting in low-cost sensor systems or sensor networks for all kinds of applications. With low energy consumption, the deployment of close meshed sensor networks is becoming a reality, promising high density data for big data models. However, data quality is not necessarily a feature of such devices, since the device output signals are heavily processed and the insight into the actual operating technique is black-boxed by the respective sensor manufacturer. High volume production of a sensor model requires widely applicable output information, yet this mainstreaming negatively impacts quality control efforts on the system level as well as niche applications that require specialized operation modes. This article exemplarily examines the measurement chain of typical metal oxide semiconductor sensor applications and deduces requirements for a technically sound advancement of the subject for research and commercial purposes. Equivalent considerations can be made for any low-cost sensor principle and their respective challenges. The conclusion urges all stakeholders participating in the development and marketing of sensor devices to advance a scientifically valid state of knowledge and to educate their customers and even the general public accordingly.","PeriodicalId":93754,"journal":{"name":"Frontiers in sensors","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138995090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges and proposed solutions for optical reading on point-of-need testing systems 在需求点测试系统上进行光学读取的挑战和拟议解决方案

Frontiers in sensors Pub Date : 2023-12-15 DOI: 10.3389/fsens.2023.1327240

F. Schaumburg, C. Berli

{"title":"Challenges and proposed solutions for optical reading on point-of-need testing systems","authors":"F. Schaumburg, C. Berli","doi":"10.3389/fsens.2023.1327240","DOIUrl":"https://doi.org/10.3389/fsens.2023.1327240","url":null,"abstract":"A broad spectrum of application fields, including human and animal health, food safety and environmental monitoring, require performing real time, on-field chemical determinations, a concept known as point-of-need testing (PONT). In the case of infectious diseases, it allows for early diagnosis, which usually enables better treatment options for the patient, and permits early outbreak detection and intervention with proper control measures. PONT solutions are usually developed on microfluidic chips, preferably with no extra equipment, as to lower their cost, ease their delivery and portability. However, equipment-free PONT is not always feasible, since off-chip operations (e.g., pumping or heating) might be required and provided by the so-called analyzers. A typical example is the hardware for optical reading, which is the subject of this perspective article. Firstly, the state-of-the-art is briefly analyzed considering the solutions provided by both academy and industry. Special emphasis is made on the smartphone-based approaches that use no additional hardware (add-ons) for optical reading. Smartphones are the straightforward option, since they can replace a number of operations typically done by analyzers. The issues arising from using smartphones without add-ons are classified into variability sources and technical challenges. Finally, a set of methods for dealing with these challenges is proposed and briefly discussed. Simpler systems will be more easily adopted by more users, for a broader range of application cases, and will let PONT be a more powerful tool for improving disease diagnosis and outbreak management.","PeriodicalId":93754,"journal":{"name":"Frontiers in sensors","volume":"244 4‐5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138997049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The future of personalized cardiovascular medicine demands 3D and 4D printing, stem cells, and artificial intelligence 个性化心血管医学的未来需要 3D 和 4D 打印、干细胞和人工智能

Frontiers in sensors Pub Date : 2023-12-05 DOI: 10.3389/fsens.2023.1294721

Monique Bax, Jordan Thorpe, Valentin Romanov

{"title":"The future of personalized cardiovascular medicine demands 3D and 4D printing, stem cells, and artificial intelligence","authors":"Monique Bax, Jordan Thorpe, Valentin Romanov","doi":"10.3389/fsens.2023.1294721","DOIUrl":"https://doi.org/10.3389/fsens.2023.1294721","url":null,"abstract":"Cardiovascular diseases remain the most lethal disorders worldwide. Employing preeminent techniques is paramount for addressing this global challenge. Recent advances in lab-on-a-chip technology have the potential to transform cardiovascular medicine by providing new tools for understanding the biological variability that underlies disease and drug response. Coupling improved fabrication techniques and cardiovascular cellular models with artificial intelligence-based tools for design and analysis primes the field to model and explore cardiovascular biology more accurately than ever before. The fabrication of lab-on-a-chip systems has dramatically evolved with the development of additive manufacturing technologies. Not only can 3D printing be used to fabricate intricate microfluidic networks, but now through the incorporation of smart materials, 4D printing can change the shape and properties of devices based on external stimuli. By leveraging advances in induced pluripotent stem cells, lab-on-a-chip devices open new opportunities within personalized cardiovascular medicine. As customizable systems, devices can be fabricated and populated with donor stem cell-derived cardiovascular cells to mimic the cardiovascular system. These capabilities are only going to improve with the increasingly important role of artificial intelligence in lab-on-a-chip centric design, real-time analysis, data gathering, processing and analysis. Here, we address the potential to personalize cardiovascular medicine through the lens of advances in the fabrication of lab-on-a-chip devices, development of induced pluripotent stem cells derived engineered vasculature and heart tissues, and explore how artificial intelligence continues to shape this field.","PeriodicalId":93754,"journal":{"name":"Frontiers in sensors","volume":"42 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138600490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0