Bulletin of Problems Biology and Medicine最新文献_第6页

NON-SPECIFIC ADAPTIVE REACTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST-SEGMENT ELEVATION (STEMI) AT DIFFERENT BODY WEIGHTS 不同体重急性冠状动脉综合征st段抬高患者的非特异性适应反应

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-2-169-269-277

N. Lutsiv, V. Akimova, O. Labinska, M. P. Halkevich, N. R. Demyanchuk, M. Shchurko, L. P. Kostiuk

{"title":"NON-SPECIFIC ADAPTIVE REACTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST-SEGMENT ELEVATION (STEMI) AT DIFFERENT BODY WEIGHTS","authors":"N. Lutsiv, V. Akimova, O. Labinska, M. P. Halkevich, N. R. Demyanchuk, M. Shchurko, L. P. Kostiuk","doi":"10.29254/2077-4214-2023-2-169-269-277","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-2-169-269-277","url":null,"abstract":"three research groups (79 patients) were analyzed: Group I - 28 patients with STEMI and normal body weight, Group II - 24 patients with STEMI and excess body weight, and Group III - 27 patients with STEMI and obesity of the I-III degrees. The diagnosis (acute coronary syndrome) of ACS was made based on a complex clinical, laboratory and instrumental examination. Blood was taken for the study when patients were admitted to the department. The total number of leukocytes and the leukocyte blood formula were determined by standardized methods; the type of non-specific adaptation reaction - according to the method of L.H. Harkavi; the ratio of the absolute content of neutrophils to the absolute content of lymphocytes (neutrophil to lymphocyte ratio, NLR), and the ratio of the absolute content of neutrophils to the absolute content of platelets (neutrophil to platelet ratio, NPR) was determined. The course of ACS occurs against the background of several non-specific adaptation reactions, where the stress reaction was dominant (42.8% - group I, 50% - group II, and 51.9% - group III), indicating the disease's severity. The highest level of NLR (p<0.05) was found in group III, relative to the NLR indicator in group I and group II, and the highest level of NPR was found in group III precisely in case of a stress reaction, which indicates an unfavourable prognosis for patients of this group. Determining the type of nonspecific adaptation reaction can serve as an additional indicator of the severity of the patient and allows us to assess the effectiveness of therapy in patients with STEMI. The indicators of NLR and NPR were useful and powerful indicators of adverse consequences during the hospitalization of patients with ACS. The type of adaptive response and the indicators of NLR and NPR are determined based on clinical blood analysis indicators, and they are economical biomarkers for predicting the severity of inflammation.","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88387091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

USE OF HEALTH-PRESERVING FEATURES OF LEARNING IN THE CONTEXT OF OPTIMIZATION AND IMPROVEMENT OF PEDAGOGICAL MANAGEMENT IN HIGHER MEDICAL EDUCATION 在优化和改进高等医学教育教学管理的背景下利用学习的养生特色

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2022-4-167-251-254

V. P. Bilash, N. Svintsytska, S. Bilash, O. Pronina, O. Bilanov, Ya. O. Oliinichenko, O. T. Tkachenko

引用次数: 0

STRUCTURAL ORGANIZATION OF THE ADRENAL GLANDS MEDULLA OF RATS IN NORMAL AND AFTER INFLUENCE OF FOOD ADDITIVE COMPLEX 食品添加剂复合物对正常及影响后大鼠肾上腺髓质的结构组织

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-2-169-381-386

S. Donchenko, S. Bilash

引用次数: 1

FEATURES OF THE FUNCTIONAL MORPHOLOGY OF THE PLACENTA IN CASE OF PREMATURE AMNIOTIC FLUID DISCHARGE 羊水过早排出时胎盘功能形态的特征

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-2-169-178-185

A. Hromova, N. Mitiunina, V. M. Shafarchuk, V. B. Martynenko, N. O. Prylutska, T. Liakhovska

引用次数: 0

ПОРІВНЯЛЬНИЙ АНАЛІЗ ПЕРЕБІГУ РЕПАРАТИВНОЇ РЕГЕНЕРАЦІЇ КІСТКОВОЇ ТКАНИНИ РІЗНИХ ДІЛЯНОК НИЖНЬОЇ ЩЕЛЕПИ

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2523-4110-2023-2-169/addition-14

З. З. Масна, І. В. Челпанова, Є. В. Пальтов, О. П. Адамович

引用次数: 0

CRANIOMETRIC CHARACTERISTICS OF THE OPENINGS POSITION OF THE FACIAL SKULL DIVISION DEPENDING ON THE GENDER OF A MATURE PERSON 颅统计学特征的开口位置的面部颅骨划分取决于一个成熟的人的性别

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2022-4-167-307-315

Yulia Onashko

引用次数: 0

PROOXIDANT-ANTIOXIDANT STATUS OF THE HEART OF RATS UNDER THE ACTION OF MONOSODIUM GLUTAMAT AND CORRECTION WITH MELATONIN 谷氨酸钠作用下大鼠心脏的促氧化-抗氧化状态及褪黑素校正

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-1-168-207-211

V. Pshychenko, V. Cherno, L. Chebotar, O. Yulevich, O. I. Petrova

引用次数: 0

ОСНОВНІ ЛАБОРАТОРНІ ПОКАЗНИКИ РИЗИКУ НАСТАННЯ ЛЕТАЛЬНОГО ВИСЛІДУ У ГОСПІТАЛІЗОВАНИХ ПАЦІЄНТІВ ІЗ COVID-19

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2523-4110-2023-2-169/addition-19

А. Ющук, В.С. Пикалюк

引用次数: 0

ANALYSIS OF THE STRESS-STRAIN STATE OF THE TIBIAL MODEL IN CASE OF ITS FRACTURE IN THE MIDDLE THIRD WITH VARIOUS TYPES OF OSTEOSYNTHESIS UNDER CONDITIONS OF INCREASING BENDING LOAD 增加弯曲载荷条件下，胫骨模型中三分之一骨折时不同类型骨融合的应力-应变状态分析

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2022-4-167-223-236

M. Y. Stroev, M. Berezka, V. Grigoruk, M. Karpinsky, A. Yaresko, I. Subbota

{"title":"ANALYSIS OF THE STRESS-STRAIN STATE OF THE TIBIAL MODEL IN CASE OF ITS FRACTURE IN THE MIDDLE THIRD WITH VARIOUS TYPES OF OSTEOSYNTHESIS UNDER CONDITIONS OF INCREASING BENDING LOAD","authors":"M. Y. Stroev, M. Berezka, V. Grigoruk, M. Karpinsky, A. Yaresko, I. Subbota","doi":"10.29254/2077-4214-2022-4-167-223-236","DOIUrl":"https://doi.org/10.29254/2077-4214-2022-4-167-223-236","url":null,"abstract":".9% of disabilities. The goal was to conduct a comparative analysis of the stress-strain state of models of the tibia with its fracture in the middle third with different options of osteosynthesis under the influence of bending load depending on the patient's weight. The model simulated a tibial fracture in the middle third and three types of osteosynthesis using an external fixation device (EFD), a bone plate, and an intramedullary rod. The models were studied at 700 N and 1200 N bending loads. Usually, under a bending load, the maximum stress magnitude is determined in the distal part of the tibia. When using EFD osteosynthesis, the maximum stress level is observed in the distal fragment of the tibia. The maximum stresses are determined in the fracture zone during osteosynthesis with a bone plate. Osteosynthesis with an intramedullary rod provides the lowest stress level in the fracture zone. An increase in the load value to 1200 N leads to a rise in the stress values in all model elements. The worst stress level indicators in the fracture zone and the metal structure were determined using a bone plate. With the help of EFD, osteosynthesis ensures a relatively low stress level in the fracture zone; it is worth noting the lowest stress level on the device itself. The lowest stress indicators in the fracture zone and the proximal fragment of the tibia are determined when using osteosynthesis with an intramedullary rod.","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82301340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE EFFECT OF MONOSODIUM GLUTAMATE CONSUMPTION ON CAROTID SINUS MORPHOLOGY: AN ELECTRON MICROSCOPY EXPERIMENTAL STUDY 谷氨酸钠摄入对颈动脉窦形态影响的电镜实验研究

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2022-4-167-316-321

О. О. Sodomora

引用次数: 0