E. Sharif, N. Rizk, H. Thakur, Tasnim Kurdi, Mariam Alwakeel
{"title":"Association between Genetic Variants of GC Gene at 4q13.3 and Vitamin D Concentrations in Adult Females","authors":"E. Sharif, N. Rizk, H. Thakur, Tasnim Kurdi, Mariam Alwakeel","doi":"10.35248/2167-0420.19.8.477","DOIUrl":"https://doi.org/10.35248/2167-0420.19.8.477","url":null,"abstract":"Background: Vitamin D binding protein, encoded by the GC gene (on 4q13.3), plays an important role in transporting vitamin D. Several Genome-Wide Association Studies (GWASs) have established a significant association between variants of GC gene and circulating vitamin D. Objective: This study aims to determine the association of GC gene polymorphisms with vitamin D concentrations in young healthy Arab females. Methodology: 214 female subjects from Qatar University were enrolled in this cross-sectional study. The cut-off value for optimal vitamin D levels was set at 30 ng/mL. The serum vitamin D was measured using ELISA, the genotyping of SNPs (rs2298850, rs3755967, rs2282679, rs7041, rs1155563, and rs17467825) of GC gene was performed by TaqMan assay, and the data was analyzed using SPSS software. Results: The mean age of 214 participants was found to be 21.97 years. Of these, only 182 subjects were included in this study. The data showed that 14.8% were found to have optimal vitamin D levels and 85.2% with suboptimal levels. All studied SNPs were in HWE except SNPs rs7041 and rs1155563. Using the dominant model for rs2298850, the odds ratio to have low vitamin D is 1.48 (p=0.419). Similarly, rs3755967 has a risk of 1.62 (p=0.294); rs2282679 has an odds ratio of 1.32 (p=0.549); and rs17467825 with a risk of 1.48 (p=0.40). The genotypes for vitamin D levels had no significant difference (p>0.05) for all study subjects. Conclusion: The current data showed no significant association between risk alleles of SNPs (rs2298850, rs3755967, rs2282679, rs7041, rs1155563, and rs17467825) with vitamin D levels.","PeriodicalId":93471,"journal":{"name":"Journal of women's health care and management","volume":"1 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76479512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Kebede, Fira Abamecha, Chali Endalew, Mamusha Aman, Abraham Tamirat
{"title":"User's Satisfaction with Maternity Waiting Home Services in Jimma Zone, Oromia, Ethiopia: Implications for Maternal and Neonatal Health Improvement","authors":"Y. Kebede, Fira Abamecha, Chali Endalew, Mamusha Aman, Abraham Tamirat","doi":"10.35248/2167-0420.19.8.464","DOIUrl":"https://doi.org/10.35248/2167-0420.19.8.464","url":null,"abstract":"Background: Maternity waiting home (MWH) is a temporary residence where pregnant women who rarely access basic obstetric cares stay. Objective: The study was aimed to assess women’s MWH satisfaction. Methods: A cross-sectional study was conducted in three randomly selected districts of Jimma zone, Oromia, Ethiopia. A sample of 362 women who ever used MWH was recruited in the study. The sample size was proportionally allocated to each district. A simple random sampling was used. Data were collected using a pretested questionnaire-developed mainly based on MWH guideline. MWH standard of construction and utensils, services, social support and interpersonal communication (IPC) etc. were the major components of the tools. Data were analyzed using Statistical package for social sciences (SPSS) version 21.0 statistical software. Reliability analysis was conducted for specific and overall satisfaction domains. Multiple linear regressions (β) were performed to identify predictors of satisfaction with MWH, p<0.05. Result: A total of 362 mothers were participated in the study (response rate=98%). The overall mothers ’ satisfaction with MWH was 68.8%. Higher mothers’ satisfaction was from social support aspects: one to five women network (89.5%), cleaner/servant in MWH (88.9%) and husband (87.3%). And, lower satisfaction was from ambulance (24%), recreational (38.5%) and food (49.4%) services and utensils in MWH (56.2%). Nearly 2/5th users claim they do not come again and recommend MWH for others. Women’s overall satisfaction with MWH was predicted by: length of stay in MWH (≤ 14 days), utensils in MWH, services (prenatal, food, sanitation, recreational), social supports (family, women’s 1-5 networks, and servants) and IPC with Health Care Workers (HCWs). Conclusion: Women ’ s overall satisfaction with MWH was moderate (68.8%). However, most services (ambulance, recreational, food, sanitation) and MWH standard (construction and utensils) were lower extreme of satisfaction dimensions. Most services and length of stay in MWH predicted overall satisfaction; indicating MWH recommended services were also valuable for users. These low satisfaction and predictor variables will be barriers to women who never used and stopping return use. The health system should avail services recommended by the guideline while strengthening social support, and shorter stay in MWH so that users advocate the innovation.","PeriodicalId":93471,"journal":{"name":"Journal of women's health care and management","volume":"48 32 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79548048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical case report: Conservative treatment of nodular adenomyosis","authors":"Zakharenko Nf, Kovalenko Nv, Manoliak Ip","doi":"10.18370/2309-4117.2018.40.44-48","DOIUrl":"https://doi.org/10.18370/2309-4117.2018.40.44-48","url":null,"abstract":"The article describes the clinical case of the nodular form of adenomyosis, first detected in a patient at the age of 16 years after another appeal to a gynecologist in connection with pronounced prolonged dysmenorrhea with ultrasound of a small pelvis. After the diagnosis of “Nodular form of adenomyosis”, the patient received 6 injections of triptorelin acetate 3.62 mg, resulting in an adenomyosis node decreased in size from 72 x 68 mm to 31 x 29 mm. Taking into account the developed side effects (aches in bones, hot flushes, weakness, tachycardia), therapy with triptorelin was discontinued. Clinical efficacy persisted for 6 months, after which painful menstruation resumed. Two years later, the patient was urgently transferred to the gynecological department of the Kyiv City Clinical Hospital No. 9 with severe manifestations of dysmenorrhea. With ultrasound of the pelvic organs, an endometrioid node in the uterus measuring 50 x 46 mm was found. The patient was recommended receiving Visanne (dienogest) in a dose of 2 mg, which she took 1 year and 10 months, being under constant supervision of the clinic’s specialists. The unauthorized break in treatment, which the patient explained with good health, provoked the resumption of painful symptoms. Visanne was continued for 2 years, as a result of which the endometrioid node decreased to 21.0 x 16.7 mm. In April 2017, in connection with the patient’s marriage and the desire to become pregnant, the reception of the dienogest was canceled. It is proposed to take a plant complex of antiproliferative action containing indole-3-carbinol 200 mg and green tea extract 82 mg. After 8 months, the patient was diagnosed with a pregnancy at 4 weeks, against which the adenomyosis node decreased to 18.1 x 11.1 mm. The results of the first two ultrasound screenings of the fetus in the gestation period of 13 and 18 weeks are described. There were no deviations in fetal development, and the endometriosis focus in the uterus was not clearly visualized at the first screening. The importance of the problem of secondary dysmenorrhea on the background of endometriosis, the establishment of a timely diagnosis and the choice of the right treatment tactics on which the future reproductive health of a teenage girl directly depends.","PeriodicalId":93471,"journal":{"name":"Journal of women's health care and management","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81436721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Soares, Carla Duarte, P. Oliveira, A. Andrade, J. M. Furtado
{"title":"The Influence of Gestational Diabetes Mellitus Diagnosis Trimester on Maternal-Fetal Outcomes","authors":"A. Soares, Carla Duarte, P. Oliveira, A. Andrade, J. M. Furtado","doi":"10.35248/2167-0420.19.8.460","DOIUrl":"https://doi.org/10.35248/2167-0420.19.8.460","url":null,"abstract":"Gestational Diabetes Mellitus (GDM) is defined as a carbohydrate intolerance that results in hyperglycemia of varying severity with onset or first recognition during pregnancy. It is known that this intolerance, which can appear from the early stage to the end of pregnancy, can cause several maternal-fetal complications during pregnancy, delivery and postpartum. Our objective was to compare maternal-fetal outcomes according to whether the diagnosis of gestational diabetes mellitus was made in the first or second trimester of pregnancy. For this purpose, a retrospective study was conducted with a consecutive sample of 194 pregnant women followed in the gestational diabetes mellitus appointment at Hospital da Senhora da Oliveira -Guimaraes. This analysis showed that there are statistically significant associations between gestational diabetes mellitus diagnosis trimester and the variables obesity and maternal comorbidities. On the other hand, no differences with statistical meaning were found regarding maternal age or used therapy when comparing cases of diagnosis made in the first and second trimesters. Regarding maternal-fetal outcomes, there are no significant associations between the different variables (preeclampsia, onset of labor, oxytocic acceleration, type of delivery, labor instrumentation, prematurity, newborn hospitalization time, macrosomia, hyperbilirubinemia, hypoglycemia and the postpartum reclassification of glycemic status) with the diagnosis trimester. We conclude that the trimester in which gestational diabetes mellitus is diagnosed is not a preponderant factor for maternal-fetal outcomes. This study also showed that a BMI<30 kg per m2 appears to be an independent factor, protective against the diagnosis in the first trimester. Other studies addressing this issue will be necessary to validate these results.","PeriodicalId":93471,"journal":{"name":"Journal of women's health care and management","volume":"46 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78975442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Saleh, A. Elsayad, E. Mahfouz, Walid A. Abdelsalam
{"title":"Low Doses of Vaginal Misoprostol versus Dinoprostone for Induction of Labor in Uncomplicated Term Pregnancy","authors":"H. Saleh, A. Elsayad, E. Mahfouz, Walid A. Abdelsalam","doi":"10.4172/2167-0420.1000457","DOIUrl":"https://doi.org/10.4172/2167-0420.1000457","url":null,"abstract":"Background: Prospective cohort observational study to compare the efficacy low doses (25 micrograms misoprostol) tablet with dinoprostone gel (1 mg) introduced vaginally in term pregnancy for induction of labor as regard maternal and fetal outcome. Methods: Three hundred pregnant women in full term (40-41 weeks) pregnancy were assigned for induction of labor either intravaginal misoprostol tablet or dinoprostone gel. They were divided into 2 groups (A, B). Group A (150 ladies) obtained tablet misoprostol 25 micrograms vaginally 4 hourly and Group B (150 ladies) received dinoprostone gel 1 mg vaginally every 6 hourly, both medications were not to be repeated more than 3 doses. Outcomes were: expression of time interval of induction of labor, augmentation requirement, operative and instrumental rate, expenditure efficiency and neonatal outcome. Results: The demographic criteria as regard the age, body mass index, gestational age, initial Bishop’s score and final Bishop’s score were analogous in both group (the misoprostol and dinoprostone groups), respectively with no significant differences but about parity there was significant difference between them with p value 0.4. No significant differences between both group as regard occurrence of non-reassuring FHR, uterine hyper stimulation and meconium stained amniotic fluid but there was significant differences in spontaneous rupture of the membranes and uterine tachysystole with p value 0.02 and 0.01, respectively. Time of labor induction was shorter in the misoprostol group with p<0.001. The need of more doses was fewer in G1 than G2 with p value 0.03. Also the need to oxytocin for augmentation was lesser in G1 than G2 with p value 0.02. In misoprostol group more deliveries within 24 hour, p<0.04. The vaginal deliveries were more in misoprostol group with lesser percentage of CS but with no significant difference. The fetal outcome in both group was similar according to birth weight, Apgar score and at 5, the requirement for neonatal resuscitation and neonatal intensive care unit admission. Conclusions: The time interval for induction of labor by misoprostol tablet vaginally was shorter than dinoprostone gel, associated with fewer requirements to augmentation of labor with oxytocin and more deliveries in the first 24 hours of induction.","PeriodicalId":93471,"journal":{"name":"Journal of women's health care and management","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89917075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On the cusp of life and death, choose life","authors":"S. Wellington","doi":"10.4172/2572-4983-c3-007","DOIUrl":"https://doi.org/10.4172/2572-4983-c3-007","url":null,"abstract":"","PeriodicalId":93471,"journal":{"name":"Journal of women's health care and management","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91313855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Health Care Provider Support for Physical Activity in Women, Aged 20-44 Years, in Georgia: A Qualitative Study","authors":"D. Nazaruk, S. Tedders, A. Hansen","doi":"10.4172/2167-0420.1000447","DOIUrl":"https://doi.org/10.4172/2167-0420.1000447","url":null,"abstract":"Background: Despite the benefits of physical activity, only 12.1% of women in rural Georgia aged 20-44 years, fully adhere to the recommended amount of physical activity. According to previous research studies, health care provider support is an important factor in promoting physical activity among patients. Methods: The purpose of this qualitative study was to understand the presence and importance of the health care provider support for physical activity in women aged 20-44 years. A semi-structured question guide directed by a Critical Theory of Medical Discourse was utilized for twenty in-depth interviews. To answer qualitative questions of the study, an intensity sampling was used to identify excellent examples of the phenomenon of interest. The participants were interviewed until theoretical saturation was reached. Results: The majority of the participants felt more comfortable having a woman as their primary health care provider, Most participants utilized the Obstetrician-Gynecologist (OBGYN) for the primary care, physical activity information was provided mostly to patients who were overweight, provided physical activity information wasn’t sufficient nor tailored to each patient. Conclusion: Primary care setting could be a powerful outlet for the promotion of physical activity. However, health care providers might need to expend the range of expertise and collaborate with other community members to increase the physical activity level among women aged 20-44 years.","PeriodicalId":93471,"journal":{"name":"Journal of women's health care and management","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78075815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Awareness and Experiences of Pregnant Women towards Antenatal Weight Management at a Maternity Hospital in Najran City, KSA","authors":"Nasser Saeed Al-Qahtani","doi":"10.4172/2167-0420.1000417","DOIUrl":"https://doi.org/10.4172/2167-0420.1000417","url":null,"abstract":"Background: One of health priorities for women during pregnancy is the attainment of healthy weight both in the antenatal and postpartum periods. This study is aiming to evaluate pregnant women awareness and experiences towards the management of obesity and weight gain during pregnancy. Method: This was a cross-sectional study (n=416) conducted over 3 months in 2017 of pregnant women attending antenatal clinics at a maternity hospital, Najran city, KSA. An interviewer administered, questionnaire was used. Findings: Results were shown 58.7% of participants (n=244) had low awareness for management of obesity and weight gain during pregnancy, with the highest level of awareness regarding management objectives and strategies (77.2%), while the lowest level of awareness folic acid (44%). In addition, 90.4% (n=376) showed poor experience in counselling about obesity management in pregnancy. Four risk factors were shown to be important indicators of awareness and experience of participants with largest being an occupation (Adjusted OR=2.7, p=0.001), nationality (Adjusted OR=2.4, p=0.015), regular follow up (Adjusted OR=1.7, p=0.049) and education level (Adjusted OR=1.3, p=0.009). Conclusion: Study findings are consistent with earlier findings indicating that low level of awareness for management of bodyweight during pregnancy in addition to bad experience in counselling about recommended guidelines for that may explain up to some extent why women are not being served appropriately regarding bodyweight and its health risks in the antenatal care.","PeriodicalId":93471,"journal":{"name":"Journal of women's health care and management","volume":"6 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2018-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88543861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anxiolytic Benefits of Exercise Classes for Mothers","authors":"J. Currie","doi":"10.4172/2167-0420.1000442","DOIUrl":"https://doi.org/10.4172/2167-0420.1000442","url":null,"abstract":"Objective: The importance of women accessing physical activity has been shown in the literature as being even more critical for wellbeing following birth of a child. As there is scant research available specifically purporting the mental health benefits of exercise classes, this paper examines the anxiolytic or anxiety-reducing benefits gained from involvement in a 3-month, twice-weekly group low-impact exercise class program for a group of mothers (n=21). Method: Quantitative data were obtained by measuring acute pre and post-changes (or pre and post-60 minutes interval for the exercise group and a non-exercising control) in the level of state anxiety (i.e. how you feel ‘right now’), through the Spielberger et al. State Anxiety Inventory (STAI). Results: The mean state anxiety levels experienced pre and post-activity showed a significant change (decrease) in exercising mothers as compared to non–exercising mothers at both Week 1 (Measurement A) and at 12–weeks (Measurement B) (p<0.05). Conclusion: Mothers are able to experience a decrease in acute anxiety following participation in exercise classes. Further strategies that allow for enhanced access and the continuation of care of children or relatives by others while the mother takes time out for health promoting exercise for leisure will need to be developed.","PeriodicalId":93471,"journal":{"name":"Journal of women's health care and management","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75575807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Menopausal transition and its association with the quality of life of women aged 40-55 of varying ethnicity in county St. Patrick West, Trinidad: A community based survey","authors":"Lesley Kuliukas","doi":"10.4172/2167-0420-C1-007","DOIUrl":"https://doi.org/10.4172/2167-0420-C1-007","url":null,"abstract":"","PeriodicalId":93471,"journal":{"name":"Journal of women's health care and management","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84419477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}