Journal of Chittagong Medical College Teachers' Association最新文献

{"title":"Association of Insulin Resistance with Dyslipidemia in Gestational Diabetes Mellitus","authors":"Hafsa Hasina, Md. Hafizul Islam, M. Haque, Razaul Karim, Shammi Akter, Ummey Salma","doi":"10.3329/jcmcta.v33i1.67167","DOIUrl":"https://doi.org/10.3329/jcmcta.v33i1.67167","url":null,"abstract":"Background: Gestational Diabetes Mellitus is the most common metabolic condition during pregnancy. Insulin resistance is a known risk factor for development of GDM. Women with Gestational Diabetes Mellitus are at increased risk for developing dyslipidemia. The aim of this study was to evaluate the occurrence of Dyslipidemia among women with GDM.  \u0000Materials and methods: This cross-sectional comparative study was conducted in Obstetrics and Gynecology Department, Chittagong Medical College Hospital. 100 patients were taken by non-probability convenience sampling where 70 women with GDM were taken as cases and 30 normal pregnant women as controls.\u0000Results: GDM cases presented significantly higher mean HOMA-IR values and increased serum TC, TG, LDL-C and decreased HDL than those of controls. So from this point of view GDM cases had both insulin resistance and dyslipidemia. GDM patients with Insulin resistance had significantly higher Triglyceride level and decreased serum HDL-C level when compared to non-insulin resistance state of the same. This study revealed significant association of insulin resistance with dyslipidemia (Increased TG and decreased HDL-C, p<0.01) in GDM.\u0000Conclusion: Insulin resistance was significantly associated with dyslipidemia in GDM. Soestimation of fasting lipid profile and fasting insulin in women with GDM may provide baseline information in course of planning and management of GDM patients.\u0000JCMCTA 2022 ; 33 (1) : 40-45","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88982550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Six Months Analysis of COVID-19 Death : Experience From a Tertiary Hospital, Chattogram","authors":"Rajat Sanker Roy Biswas, J. Nath, Fatema Emrose Nisha, P. Sarker","doi":"10.3329/jcmcta.v33i1.67183","DOIUrl":"https://doi.org/10.3329/jcmcta.v33i1.67183","url":null,"abstract":"Background : COVID 19 pandemic had taken away lots of human life prematurely worldwide and death laid its icy hands also on Bangladesh. So, objectives of this study were to explore the monthly distributions, age, sex, comorbidities, localities and duration of hospital stay among the COVID 19 death cases.   \u0000Materials and methods: In this observational study six months hospital death registries were collected and explored for monthly distributions, age, sex, comorbidities, localities and hospital stay.  RT-PCR positive confirmed 113 COVID deaths were enrolled and suspected COVID deaths were excluded. Ethical clearance from the hospital authority was taken before hand. Data was compiled and analyzed by SPSS-20. \u0000Results: There was a low frequency of death in the months May-2021 and October-2021(7.1% and 2.7% respectively) but more during June -2021 to September 2021 (12.4%, 16.8%, 42.5% and 18.6% respectively). Female deaths were   more than male deaths (53.1% vs 46.9%, p<0.05). Age more than 51 years were the most vulnerable where 26(23%) deaths were at age group 51- 60 years, 39(34.5%) deaths were at 61-70 years and 22(19.4%) deaths were more than 71 years.  Mean age of death was found 60.66 years and mean duration of hospital stay was found 9.45 days.  Maximum duration of hospital stay was 45 days for one patient.  Co-morbidities of death cases revealed 52(46.00%) patients had DM and HTN both, 17(15.0%) patients had HTN, 16(14.1%) had DM, 3(2.6%) had BA and COPD, 4(3.5%) had CKD, 2(1.7%) had cancer, 3(2.6%) had CVD, 19(16.8%) had IHD and 16(14.1%) patients had no co-morbidities. Locality of the death cases revealed 44(38.9%) patients came from rural areas and 69(61.1%) came from urban areas.   \u0000Conclusion: Higher age group and multiple comorbidities specially DM, HTN and IHD were related with COVID deaths mostly found in our study. \u0000JCMCTA 2022 ; 33 (1) : 46-49","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85071195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malnutrition in Children with Uncomplicated Versus Complicated Appendicitis","authors":"Md Tameem Shafayat Chowdhury, Rajib Khastagir, T. A. Chowdhury, Md. Abdullah Al Farooq, Md Khurshid Alam Sarwar, T. Chowdhury","doi":"10.3329/jcmcta.v33i1.67195","DOIUrl":"https://doi.org/10.3329/jcmcta.v33i1.67195","url":null,"abstract":"Background : Acute appendicitis is one of the commonest surgical emergencies in children and malnutrition is prevalent in the country. This study was designed to compare if complicated appendicitis occurs more in malnourished children. \u0000Materials and methods: This cross-sectional study was conducted in Department of Paediatric Surgery, Chittagong Medical College Hospital from March 2017 to December 2019 with 155 children. Anthropometric measurements (Height, weight, Mid Upper Arm Circumference (MUAC) Triceps Skin Fold Thickness (TSFT) were recorded and biochemical assessment (Haemoglobin, albumin and total lymphocyte count) were done before surgery. Patients were grouped into two groups: Group A (Acute uncomplicated appendicitis; n=65) and Group B (Acute complicated appendicitis, n=90). Anthropometric and biochemical indices were compared between these two groups.   \u0000Results: Age ranged from 2 -12 years (Mean 9.2 ±2.5 years) (Male: female- 1.35:1). Among the five anthropometric indices abnormal measurements in Group A vs Group B were respectively. Abnormal TSFT (73.8% vs 80%, p=0.4) wasting (38.5% vs 44.4%, p=0.4) low MUAC for age (13.8% vs 17.8%, p=0.8) low weight for age (30.8% vs 36.7%, p=0.5) and low height for age (21.5% vs 24.4%, p=0.7) low albumin (52.3% vs 83.3%, p<0,001); low haemoglobin (61.5% vs 60.0%, p=0.6)) and low total lymphocyte count (39.5% vs 44.8%, p=0.7). \u0000Conclusions: Malnutrition was widely prevalent in both groups. Although the proportion of malnutrition was more with acute complicated appendicitis, it was not statistically significant. The lower serum albumin level in these patients might be due to the consequence of the disease rather than prevailing malnutrition. \u0000JCMCTA 2022 ; 33 (1) : 66-70","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86140018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factor Evaluation of Non Alcoholic Fatty Liver Disease in Lean Individual","authors":"M. N. Mohsin, Salahuddin Mohammed Ali Haider, F. Akter, E. Ahmed, B. Paul","doi":"10.3329/jcmcta.v33i1.67194","DOIUrl":"https://doi.org/10.3329/jcmcta.v33i1.67194","url":null,"abstract":"Background : Non-Alcoholic Fatty Liver Disease (NAFLD) is epidemic around the world. Bangladesh is also experiencing an increasing trend of NAFLD. Obesity is a common clinical phenotype associated with NAFLD, which is linked to metabolic syndrome and related comorbidities, including type II diabetes, hypertension and dyslipidemia. Clearly, not all obese subjects develop NAFLD and NAFLD also can be found in non-obese patients. This subset of individuals, known to have ‘lean NAFLD’ or ‘non-obese NAFLD’, is growing increasingly prevalent. NAFLD in lean patients appears to be more common among Asians. So it is important to look for risk factors for NAFLD in lean patients for prevention of advanced liver disease. The objective of our study was to find out the risk factors of NAFLD in lean (Nonobese) individual. \u0000Materials and methods: It was prospective observational study done on 100 patients attending in the Gastroenterology Department and OPD of Chittagong Medical College Hospital after approval of Ethical and Review Committee of CMC and grant from DGHS. Total 100 patients having 18 to 65 years of age, were taken as study subjects who met inclusion criteria. Informed written consent was obtained from the patients or attendant after full explanation of the purpose of the study. Fasting Blood Glucose (FBS) Fasting lipid profile, SGPT, SGOT, Ultrasonography of hepatobiliary system and Fibrosan were done. All necessary data was included in the data collection sheet and was analyzed by Microsoft excel and SPSS-23. \u0000Results: 100 patients were included in this study. Mean age of this study with age was in between 18 years to 65 years.Male to female ratio was 3:1 in the studied population.The majority of the lean patient with NAFLD (31%) was in the age group 40-49 years. The majority of the lean patient with NAFLD (83%) was in normal BMI range 18.5-22.99 kg/m2 and 13% had BMI <18.50 kg/m. Out of 100patients diabetes and hypertension were found 22% and 17% of patients respectively. 22% and 17% patients. 65% and 37% patients had raised SGPT and SGOT respectively. Out of 100 subjects, 50% had raised triglyceride level (50%) and 18% had raised LDL cholesterol (18%) level.According to Ultrasonography findings 68% were in Grade I, 11% in Grade II and only 1 patient was in Grade III fatty liver. Fibroscan of 100 subjects, Significant fibrosis ( ³2 F) was observed in 9%,  while advanced fibrosis (F4) was seen in 4% of patients.  As per steatosis score 36% was in S2 and 34% were in S3 grade. Median fibrosis score and steatosis score was significantly higher in patients with high SGPT compared to patients with normal SGPT (p <0.005) whereas median fibrosis score and steatosis score was higher in patients with high SGOT compared to patients with normal SGOT, but only the difference in steatosis score reached statistical significance (p<.042). AUC of SGPT for discriminating fibrosis grade F0-F1 from Grade F2-F4 was 0.565 (95% CI: 0.404-0.726, p=0.519). AUC of SGOT for","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86426889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Serum C-Peptide with the Components of Metabolic Syndrome among Non Diabetic Obese","authors":"Shammi Akter, Md. Hafizul Islam, M. Haque, N. Tasnim, Hafsa Hasina, Mosammat Tanjina Akther","doi":"10.3329/jcmcta.v33i1.67411","DOIUrl":"https://doi.org/10.3329/jcmcta.v33i1.67411","url":null,"abstract":"Background: Obesity is a major health concern and is associated with metabolic syndrome that increases the risk for cardiovascular disease and diabetes mellitus. C-peptide or connecting peptide, is a short polypeptide that connects A-chain of insulin to its B-chain in the proinsulin molecule.  In different studies it was found that C-peptide level are associated with Metabolic Syndrome and its complication. C-peptide is also reported to be more reliable than insulin as a measure of endogenous insulin secretion, insulin resistance and pancreatic beta cell function. The aim of the study is to observe the association of C-peptide levels with the components of metabolic syndrome in non diabetic obese subjects. \u0000Materials and methods: This was a hospital based cross- sectional study comprising hundred non diabetic apparently healthy obese subjects age between 30-70 years. This study was carried out at the Department of Biochemistry and Outpatient Department of endocrinology, Chittagong Medical College Hospital. Samples were collected by non-probability convenient sampling.   \u0000Results: Serum C-peptide was significantly higher in Metabolic Syndrome positive subjects (4.29 ±0.28 ng/ml) than non-Metabolic Syndrome (1.72 ± 0.12ng/ml). There was significant association between Metabolic Syndrome and increased serum C-peptide concentration. Serum Cpeptide levels were significantly associated and positively correlated with serum triglyceride, blood pressure, fasting plasma glucose and negatively correlated with HDL-C in the cases. \u0000Conclusion: However, this study did not find any significant association between WC (Waist Circumference) or HDL and Serum C-peptide concentration. Higher Cpeptide level was associated with the components of Metabolic Syndrome and BMI (obesity) was the most important factor affecting the C-peptide concentration to develop Metabolic Syndrome. \u0000JCMCTA 2022 ; 33 (1) : 148-153","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75744117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Sociodemographic Characteristics, Clinical Profile and Pattern of Pathogens of Meningitis in Children Admitted in A Tertiary Level Medical College Hospital","authors":"K. Nahar, Md. Shah Alam, M. Chowdhury, N. Nahar","doi":"10.3329/jcmcta.v33i1.67225","DOIUrl":"https://doi.org/10.3329/jcmcta.v33i1.67225","url":null,"abstract":"Background: CNS Infection are likely to arouse tremendous anxiety in both the physician and the patients. It is one of the most potentially serious infections occurring in children and important cause of mortality and morbidity in worldwide. Laboratory surveillance of pathogen is crucial in formulating the empirical treatment guidelines. To evaluate sociodemographic characteristics, clinical profile and pattern of pathogens of meningitis in children. \u0000Materials and methods: A descriptive study was carried out in paediatric Inpatient Department of Pediatric CMCH (Chittagong Medical College Hospital) Chattogram during the period of May 2013 to April 2014 where History, clinical examination and CSF sample were obtained from 40 patients of suspected meningitis. Diagnosis was based on the clinical presentation and CSF analysis.   \u0000Results: In this study, out of 40 patient, 25 patients were diagnosed as bacterial meningitis and 15 patient were diagnosed as aseptic meningitis based on clinical features and CSF analysis. 20% Culture positive bacterial menigitis was found, S pneumonae was found the leading pathogen. Overall, mortality rate was 2.5 %. \u0000Conclusion: Bacterial meningitis is a medical emergency. Making an early diagnosis and prompt treatment are lifesaving. For Starting early empirical treatment of meningitis, knowledge about the local pathogen is necessary. \u0000JCMCTA 2022 ; 33 (1) :77-81","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80020164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Value of Urinary Neutrophil Gelatinase-Associated Lipocalin in Detecting Acute Kidney Injury in Asphyxiated Term Neonates","authors":"M. Hossain, S. Biswas, M. Islam, Md. Akram Ullah, N. Sultana, Fuad Md Abdul Hadi, Muhammad Jabed Bin Amin Chowdhury, J. C. Das","doi":"10.3329/jcmcta.v33i1.67419","DOIUrl":"https://doi.org/10.3329/jcmcta.v33i1.67419","url":null,"abstract":"Background: Neonates with Perinatal Asphyxia (PNA) are at higher risk for developing Acute Kidney Injury (AKI). Conventionally, Serum Creatinine (SCr) is used to diagnose AKI but lacks specificity during the first few days of life. Neutrophil Gelatinase-Associated Lipocalin (NGAL) has emerged as a novel biomarker of AKI in such situations, while its value in our setting is yet to be validated. The study aimed to evaluate the role of urinary NGAL (uNGAL) level as a predictive biomarker of AKI in term newborn infants with PNA. \u0000Materials and methods: This prospective observational study included 55 full-term neonates with PNA from the Special Care Neonatal Unit of Chittagong Medical College Hospital.The uNGAL was measured by an enzyme-linked immunosorbent assay. Urinary samples were obtained for uNGAL on postnatal day 1(after 6 hours), and on day 3, blood samples for sCr were obtained on postnatal day1, 3 and 6. \u0000Results: Among 55 neonates with PNA, 20 (36.4%) had AKI. The mean ±SD uNGAL level was 97.77±17.13 ng/ml in neonates with AKI compared to 25.76±2.19 ng/ml in those without AKI in the first postnatal day. An uNGAL cutoff value of 28.86 ng/ml had 90.0% sensitivity and 82.9% specificity in predicting AKI the same day. The mean value of uNGAL was observed at a lower level, 54.53±14.72 ng/ml vs 15.17±2.18 ng/ml in AKI and no AKI neonates on third postnatal days. The cutoff value for detecting AKI was seen to be 26.43 ng/ml with high validity on this day. Significant differences in sCr were observed between AKI and no AKI measuring on days one and three, whereas the difference was not significant on day six. \u0000Conclusion: The study showed that uNGAL might be a valuable biomarker for predicting AKI among neonates with PNA. \u0000JCMCTA 2022 ; 33 (1) : 173-177","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79299352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Etiological Spectrum of Diseases Among the Patients Presenting with per Rectal Bleeding Attending at Surgery Outpatient Department in a Tertiary Level Hospital","authors":"Mayin Uddin Mahmud, M. Hossain, Ajoy Kumer Ghosh, R. Reza","doi":"10.3329/jcmcta.v33i1.66908","DOIUrl":"https://doi.org/10.3329/jcmcta.v33i1.66908","url":null,"abstract":"Background: Per rectal bleeding is a problem that is frequently encountered by doctors. There is marked geographical variation in the frequency of different etiologies. This study was conducted to determine the frequency of various causes of per rectal bleeding in patients attending in a tertiary level hospital in Chittagong, Bangladesh. \u0000Materials and methods : It was a retrospective study, and non-probability purposive sampling was done. All the patients over ten years of age presenting at the Surgery Outpatient Department with the complain of per rectal bleeding were included. A total of 685 patients were included in this study over a period of 2 years. \u0000Results: Mean age of the patients was 36 ± 13 (Mean ± SD) with a range of 10-82 years. Male-female ratio was 1.5:1. Haemorrhoids were the most common cause (34.6%) of per rectal bleeding, followed by chronic anal fissure (26.1%), chronic anal fissure with haemorrhoids (14.9%), colorectal polyps (11.4%) colorectal cancer (8.3%) and Inflammatory Bowel Diseases (IBD) (0.9%). No cause of per rectal bleeding was found in 3.8% of patients. Maximum patients with colorectal cancer presented in their fifth and sixth decades of life.   \u0000Conclusion: Haemorrhoids and fissures in ano are the most common causes of per rectal bleeding in our setting. However, the number of colorectal polyps and colorectal cancers are not negligible. \u0000JCMCTA 2022 ; 33 (1) : 9-14","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88383068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of Frozen Section Biopsy in the Diagnosis of Ovarian Malignancy : An Institutional Experience","authors":"Ismat Sultana, Mohammad Azizul Haque, N. Sultana, Nazmin Sultana, B. Nessa","doi":"10.3329/jcmcta.v33i1.67291","DOIUrl":"https://doi.org/10.3329/jcmcta.v33i1.67291","url":null,"abstract":"Background: Women with early-stage ovarian cancer need surgical staging, which entails taking samples from areas within the abdominal cavity and retroperitoneal lymph nodes for further treatment. The frozen section is an essential and beneficial adjunct in the intraoperative diagnosis of ovarian tumors. The study aimed to evaluate the diagnostic accuracy of frozen section biopsy in malignant lesions among ovarian masses. \u0000Materials and methods: This was a cross sectional study. Thirty cases of ovarian masses from the patients who underwent laparotomy for ovarian massesat the Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from March 2014 to August 2014 were included in the study. Surgical specimens were first processed for frozen section reporting, then processed routinely for final paraffin section histopathology evaluation. Results of frozen and paraffin sections were categorized as benignand malignant, and the accuracy of the frozen section was determined. \u0000Results: The mean age was found to be 35.6±12.4 years, with a range from 14 to 70 years. Frozen section biopsy for evaluation of ovarian masses, true positive was in 6 cases and no false, one false negative and true negative in 23 cases identified by histopathology. Frozen section biopsy has a sensitivity of 85.7%, specificity of 100.0%, accuracy of 96.7%, a positive predictive value of 100.0%, and a negative predictive value of 95.8% in the evaluation of malignant ovarian masses. \u0000Conclusion: The present study confirms that frozen section diagnosis is a reliable method for the surgical management of patients with ovarian masses. \u0000JCMCTA 2022 ; 33 (1) : 144-147","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"140 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75660894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Profile of RT-PCR Positive Paediatric Patients with COVID 19: Overview from Chattogram, Bangladesh","authors":"Zabeen Choudhury, Salina Haque, Aparup Das, S. Choudhury, H. M. Hira","doi":"10.3329/jcmcta.v33i1.67287","DOIUrl":"https://doi.org/10.3329/jcmcta.v33i1.67287","url":null,"abstract":"Background: Coronavirus diseases 2019 (COVID-19) has become global pandemic. During the COVID-19 pandemics, caused by SARS-CoV-2, overall, children younger than 18 years are thought to account for only 1% to 2% of detected cases worldwide. COVID-19 has been found less frequent in children and studies on pediatric COVID-19 have also been less reported, especially from Bangladesh. To evaluate the clinical profile of RT-PCR- positive paediatric patients with COVID 19 in Chattogram region. \u0000Materials and methods: This cross-sectional study was conducted in OPD, Department of Paediatrics, Chittagong Medical Colllege Hospital (CMCH) Chattogram. All postCOVID paediatric patients reported as RT-PCR positive by Microbiology department of CMCH were enrolled in the study. The study was carried out from 1/8/21 to 31/01/22. According to inclusion/exclusion criteria 96 RT-PCR positive COVID-19 paediatric patients were taken as sample by convenient sampling for this study. The diagnosis of COVID 19 infection was confirmed by RTPCR report of nasopharyngeal or oro-pharyngeal swab. Patients, guardians were contacted over telephone to attend paediatric OPD of CMCH for clinical information & laboratory findings.   \u0000Results: Among them 96 children, 68.8% were in >5 years, 18.8% were in 1-5 years, and 12.4% were in the <1 year age group; 55.2% were female and 48.8% were male. About 66 (80%) patients had history of contact with suspected or confirmed COVID-19 patient. Total 21 patients got hospitalized. Mean ± SD of time from symptom onset to hospital admission was 4.76 ± 1.998 days. Duration of hospital stay was ranged from 4-14 days. Mean ± SD duration of hospital stay was 6.1 ± 2.385 days. Maximum (97.9%) patients had fever, 77.1% patients had cough and 29.2% patients had vomiting.  Majority (82.3%) of the patients had no co-morbidities. Mean ± SD Hb% (g/dl) was 12.04 ± 1.817 g/dl with range: 7-16 g/dl; median (IQR) WBC (/Cumm) was 9500 (720016000) (Range: 3200-26000), median (IQR) Neutrophil (%) was 64 (54-71) (range: 14-90), median (IQR) Lymphocyte (%) was 28 (22-36) (range: 6-74) and median (IQR) Platelet count (/Cumm) was 200000 (172500284000) (Range: 40000-418000). Raised CRP, D-Dimer and S. Ferritin level were found among 43 (75.4%), 8 (14.4%) and 38 (66.7%) patients respectively. Available CXR findings of 47 patients showed that, 21 (45%) had patchy opacity, 19 (40%) had no significant abnormality and 6 (13%) had bilateral consolidation. Paracetamol was the most frequently (83.2%) used drug for this infection. Oral antibiotic was used in 64.2% children, bronchodilator and zinc supplementation were given to 48.4% and 43.2% children respectively. Oxygen therapy was needed for 12.6% children. More than half (57.7%) of the patients reported to feel fatigue after COVID-19 infection. About 40.4% patients had shortness of breath, 38.5% patients had history of weight loss. And 25% patients had lost their taste/smell.   \u0000Conclusion: Clinical presentations of COVID-19 ","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72491360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}